Codelivery of SH -aspirin and curcumin by mPEG -PLGA nanoparticles enhanced antitumor activity by inducing mitochondrial apoptosis

International Journal of Nanomedicine

Volumn 10, Issue , 2015, Pages 5205-5218

  Zhou, Lin ^a,b   Duan, Xingmei ^a,b   Zeng, Shi ^a   Men, Ke ^a   Zhang, Xueyan ^a   Yang, Li ^a   Li, Xiang ^a  

^a SICHUAN UNIVERSITY   (China)

^b Sichuan Food and Drug Safety Monitoring and Review of Certification   (China)

Author keywords

Cancer therapy; Drug delivery; Ovarian cancer; Synergistic effect

Indexed keywords

CURCUMIN; HYDROGEN SULFIDE RELEASING ASPIRIN; MACROGOL; METHOXY POLY(ETHYLENE GLYCOL); NANOPARTICLE; POLYGLACTIN; PRODRUG; UNCLASSIFIED DRUG; WATER OIL CREAM; ACETYLSALICYLIC ACID; ANTINEOPLASTIC AGENT; MACROGOL DERIVATIVE; METHOXYPOLYETHYLENEGLYCOL-POLY(LACTIC-CO-GLYCOLIC ACID); POLYESTER; SOLVENT; WATER;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CARCINOMA CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG MECHANISM; DRUG POTENTIATION; DRUG RELEASE; DRUG STABILITY; DRUG STRUCTURE; DRUG UPTAKE; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; NANOENCAPSULATION; PARTICLE SIZE; CHEMISTRY; DRUG EFFECTS; MITOCHONDRION; OVARY TUMOR; PATHOLOGY; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; ASPIRIN; CELL LINE, TUMOR; CURCUMIN; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; NANOPARTICLES; OVARIAN NEOPLASMS; PARTICLE SIZE; POLYESTERS; POLYETHYLENE GLYCOLS; SOLVENTS; WATER;

EID: 84939623807     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S84326     Document Type: Article

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