Tertiary-Amine-Catalyzed Asymmetric [3+2] Annulations of Morita-Baylis-Hillman Carbonates of Isatins with Nitroolefins to Construct Spirooxindoles

Synthesis (Germany)

Volumn 47, Issue 17, 2015, Pages 2538-2544

  Peng, Jing ^a   Ran, Guang Yao ^a   Du, Wei ^a   Chen, Ying Chun ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

asymmetric 3+2 annulation; cyclopentadiene; Morita Baylis Hillman carbonates; spirooxindole

Indexed keywords

CATALYSIS; ENANTIOSELECTIVITY; OLEFINS;

ASYMMETRIC [3+2] ANNULATION; CYCLOPENTADIENES; ENANTIOSELECTIVE; NITROOLEFINS; SPIROOXINDOLE; TERTIARY AMINE;

CARBONATES;

ALKENE; CARBONIC ACID; CARBONIC ACID DERIVATIVE; ISATIN; METHYL 1' METHYL 2'OXO 5 (M TOYL)SPIRO[CYCLOPENTA[2,4]DIENE1,3' INDOLINE] 2 CARBOXYLATE; METHYL 1' METHYL 2'OXO 5 (P TOYL)SPIRO[CYCLOPENTA[2,4]DIENE1,3' INDOLINE] 2 CARBOXYLATE; METHYL 1' METHYL 2'OXO 5 (THIOPHEN 2 YL)SPIRO[CYCLOPENTA[2,4]DIENE 1,3'INDOLINE] 2 CARBOXYLATE; METHYL 1' METHYL 2'OXO 5 PHENYL 5' (TRIFLUOROCYCLOPENTA[2,4]DIENE 1,3'INDOLINE] 2 CARBOXYLATMETHOXY)SPIRO[; METHYL 1' METHYL 2'OXO 5 PHENYLSPIRO[CYCLOPENTA[2,4]DIENE1,3' INDOLINE] 2 CARBOXYLATE; METHYL 1' METHYL 2'OXO 5 [4 (TRIFLUOROMETHYL)PHENYLSPIRO[2,4]DIENE 1,3'INDOLINE] 5 CARBOXYLATE; METHYL 1',5' DIMETHYL 2'OXO 5 PHENYLSPIRO[CYCLOPENTA[2,4]DIENE1,3' INDOLINE] 2 CARBOXYLATE; METHYL 1',5',7' TRIMETHYL 2'OXO 5 PHENYLSPIRO[CYCLOPENTA[2,4]DIENE1,3' INDOLINE] 2 CARBOXYLATE; METHYL 2' (4 BROMOPHENYL) 1 METHYL 2'OXOSPIRO[CYCLOPENTA[2,4]DIENE1,3' INDOLINE] 2 CARBOXYLATE; METHYL 5' (3 FLUOROPHENYL) 1 METHYL 2'OXOSPIRO[CYCLOPENTA[2,4]DIENE1,3' INDOLINE] 2 CARBOXYLATE; METHYL 5' (4 FLUOROPHENYL) 1 METHYL 2'OXOSPIRO[CYCLOPENTA[2,4]DIENE1,3' INDOLINE] 2 CARBOXYLATE; METHYL 5' (4 METHOXYPHENYL) 1 METHYL 2'OXOSPIRO[CYCLOPENTA[2,4]DIENE1,3' INDOLINE] 2 CARBOXYLATE; METHYL 5' (FURAN 2 YL) 1 METHYL 2'OXOSPIRO[CYCLOPENTA[2,4]DIENE1,3' INDOLINE] 2 CARBOXYLATE; METHYL 5' BROMO 1 METHYL 2'OXO 5 PHENYLSPIRO[CYCLOPENTA[2,4]DIENE1,3' INDOLINE] 2 CARBOXYLATE; METHYL 5' CHLORO 1 METHYL 2'OXO 5 PHENYLSPIRO[CYCLOPENTA[2,4]DIENE1,3' INDOLINE] 2 CARBOXYLATE; METHYL 5' FLUORO 1 METHYL 2'OXO 5 PHENYLSPIRO[CYCLOPENTA[2,4]DIENE1,3' INDOLINE] 2 CARBOXYLATE; METHYL 5' IODO 1 METHYL 2'OXO 5 PHENYLSPIRO[CYCLOPENTA[2,4]DIENE1,3' INDOLINE] 2 CARBOXYLATE; METHYL 5' METHOXY 1 METHYL 2'OXO 5 PHENYLSPIRO[CYCLOPENTA[2,4]DIENE1,3' INDOLINE] 2 CARBOXYLATE; METHYL 7' FLUORO 1 METHYL 2'OXO 5 PHENYLSPIRO[CYCLOPENTA[2,4]DIENE1,3' INDOLINE] 2 CARBOXYLATE; NATURAL PRODUCT; NITROOLEFIN; OXINDOLE; SPIROOXINDOLE; UNCLASSIFIED DRUG;

ANNULATION REACTION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CATALYSIS; CHIRALITY; CONTROLLED STUDY; ENANTIOSELECTIVITY; X RAY CRYSTALLOGRAPHY;

EID: 84939565559     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0034-1378716     Document Type: Article

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