Critical role of the SPAK protein kinase CCT domain in controlling blood pressure

Human Molecular Genetics

Volumn 24, Issue 16, 2015, Pages 4545-4558

  Zhang, Jinwei ^a   Siew, Keith ^b   Macartney, Thomas ^a   O'Shaughnessy, Kevin M ^b   Alessi, Dario R ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; FANCONI ANEMIA GROUP C PROTEIN; MESSENGER RNA; PROTEIN KINASE; PROTEIN KINASE WNK1; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 2; SPAK PROTEIN KINASE; UNCLASSIFIED DRUG; PROTEIN SERINE THREONINE KINASE; SLC12A3 PROTEIN, MOUSE; SODIUM CHLORIDE COTRANSPORTER; STK39 PROTEIN, HUMAN; STK39 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BLOOD PRESSURE REGULATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; FEMALE; GENE MUTATION; GITELMAN SYNDROME; HUMAN; HUMAN CELL; HYPOCALCIURIA; HYPOKALEMIA; HYPOMAGNESEMIA; MALE; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; SALT WASTING; SODIUM RESTRICTION; AMINO ACID SUBSTITUTION; ANIMAL; BIOSYNTHESIS; BLOOD PRESSURE; GENETICS; HEK293 CELL LINE; METABOLISM; MISSENSE MUTATION; MUTANT MOUSE STRAIN; PATHOPHYSIOLOGY; PHOSPHORYLATION; PROTEIN TERTIARY STRUCTURE;

ANIMALIA; MUS;

AMINO ACID SUBSTITUTION; ANIMALS; BLOOD PRESSURE; GITELMAN SYNDROME; HEK293 CELLS; HUMANS; MICE; MICE, MUTANT STRAINS; MUTATION, MISSENSE; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; SOLUTE CARRIER FAMILY 12, MEMBER 3;

EID: 84939548432     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddv185     Document Type: Article

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