Whole-genome association study identifies STK39 as a hypertension susceptibility gene

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 1, 2009, Pages 226-231

  Wang, Ying ^a   O'Connell, Jeffrey R ^a   McArdle, Patrick F ^a   Wade, James B ^a   Dorff, Sarah E ^a   Shah, Sanjiv J ^b   Shi, Xiaolian ^a   Pan, Lin ^b   Rampersaud, Evadnie ^a   Shen, Haiqing ^a   Kim, James D ^c   Subramanya, Arohan R ^a   Steinle, Nanette I ^a   Parsa, Afshin ^a   Ober, Carole C ^b   Welling, Paul A ^a   Chakravarti, Aravinda ^d   Weder, Alan B ^e   Cooper, Richard S ^f   Mitchell, Braxton D ^a   Shuldiner, Alan R ^a   Chang, Yen Pei C ^a   more..

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^f LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

Blood pressure; Essential hypertension; Genome wide association study; SPAK; STK39

Indexed keywords

CATION; CHLORIDE; COTRANSPORTER; ELEMENT; PROTEIN KINASE WNK1; PROTEIN SERINE THREONINE KINASE; SERINE THREONINE KINASE 39; SODIUM; UNCLASSIFIED DRUG; SODIUM CHLORIDE COTRANSPORTER; STK39 PROTEIN, HUMAN;

ADULT; AMISH; ARTICLE; BLOOD PRESSURE REGULATION; CAUCASIAN; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; ESSENTIAL HYPERTENSION; FEMALE; GENE; GENE EXPRESSION; GENE FREQUENCY; GENE MUTATION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MAJOR CLINICAL STUDY; MALE; NEPHRON; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SERINE THREONINE KINASE 39 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; SODIUM URINE LEVEL; SYSTOLIC BLOOD PRESSURE; BLOOD PRESSURE; CHEMISTRY; DIASTOLE; ETHNOLOGY; GENETIC PREDISPOSITION; GENETICS; HYPERTENSION; PROTEIN BINDING; SYSTOLE; URINE;

BLOOD PRESSURE; DIASTOLE; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; HYPERTENSION; NEPHRONS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; SODIUM; SODIUM CHLORIDE SYMPORTERS; SYSTOLE;

EID: 58549108489     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0808358106     Document Type: Article

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