Lack of the transcription factor hypoxia-inducible factor 1α (HIF- 1α) in macrophages accelerates the necrosis of Mycobacterium avium-induced granulomas

Infection and Immunity

Volumn 83, Issue 9, 2015, Pages 3534-3544

  Cardoso, Marcos S ^a   Silva, Tânia M ^a,b   Resende, Mariana ^a,b,c,d   Appelberg, Rui ^a,b   Borges, Margarida ^a,e  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c UNIVERSITY OF MINHO   (Portugal)

^d UNIVERSITY OF MINHO   (Portugal)

^e UNIVERSITY OF PORTO   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; LYSOZYME; HIF1A PROTEIN, MOUSE;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GROWTH; BACTERIAL LOAD; BACTERIAL STRAIN; BONE MARROW DERIVED MACROPHAGE; COLONY FORMING UNIT; CONTROLLED STUDY; FLOW CYTOMETRY; GRANULOMA; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INFLAMMATORY INFILTRATE; LYMPHOCYTE SUBPOPULATION; MACROPHAGE; MONONUCLEAR CELL; MOUSE; MYCOBACTERIUM AVIUM; NECROSIS; NEUTROPHIL; NONHUMAN; OXYGEN SUPPLY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN CONTENT; SPLEEN CELL; SPLEEN LYMPHOCYTE; TUNEL ASSAY; VASCULARIZATION; ANIMAL; C57BL MOUSE; DISEASE MODEL; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; MYCOBACTERIOSIS; PATHOLOGY;

ANIMALS; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; GRANULOMA; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYCOBACTERIUM AVIUM; MYCOBACTERIUM INFECTIONS; NECROSIS;

EID: 84939546765     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00144-15     Document Type: Article

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