αβ T cell receptor-positive cells and interferon-γ, but not inducible nitric oxide synthase, are critical for granuloma necrosis in a mouse model of mycobacteria-induced pulmonary immunopathology

Journal of Experimental Medicine

Volumn 194, Issue 12, 2001, Pages 1847-1859

  Ehlers, Stefan ^a   Benini, Jochen ^a   Held, Heinz Dieter ^a   Roeck, Christiane ^a   Alber, Gottfried ^b   Uhlig, Stefan ^a  

^a RESEARCH CENTER BORSTEL   (Germany)

^b Molecular Pathogenesis   (Germany)

Author keywords

Granuloma; Immunopathology; Koch's phenomenon; Necrosis; Tuberculosis

Indexed keywords

CD4 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12; NITRIC OXIDE; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; T LYMPHOCYTE RECEPTOR DELTA CHAIN; T LYMPHOCYTE RECEPTOR GAMMA CHAIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LYMPHOCYTE ANTIGEN RECEPTOR; NITRIC OXIDE SYNTHASE; RECEPTORS, ANTIGEN, T CELL, ALPHA BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GRANULOMA; HISTOPATHOLOGY; IMMUNOPATHOGENESIS; KNOCKOUT MOUSE; LUNG TUBERCULOSIS; MOUSE; MYCOBACTERIUM AVIUM; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; TISSUE NECROSIS; ANIMAL; CYTOTOXICITY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOLOGY; MOUSE MUTANT; NECROSIS; PATHOLOGY; T LYMPHOCYTE SUBPOPULATION;

ANIMAL; CYTOTOXICITY, IMMUNOLOGIC; GENE EXPRESSION REGULATION; GRANULOMA; HUMAN; INTERFERON TYPE II; MICE; MICE, KNOCKOUT; MYCOBACTERIUM AVIUM; NECROSIS; NITRIC-OXIDE SYNTHASE; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTE SUBSETS; TUBERCULOSIS, PULMONARY;

EID: 0035904851     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.194.12.1847     Document Type: Article

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