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Volumn 24, Issue 16, 2015, Pages 4573-4583

CDK5 phosphorylates DRP1 and drives mitochondrial defects in NMDA-induced neuronal death

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CYCLIN DEPENDENT KINASE 5; CYTOPLASM PROTEIN; DYNAMIN RELATED PROTEIN 1; HISTONE H1; N METHYL DEXTRO ASPARTIC ACID; ROSCOVITINE; UNCLASSIFIED DRUG; CDK5 PROTEIN, MOUSE; DNM1L PROTEIN, MOUSE; DYNAMIN; N METHYLASPARTIC ACID;

EID: 84939515673     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddv188     Document Type: Article
Times cited : (74)

References (40)
  • 1
    • 0027085867 scopus 로고
    • Mechanisms of excitotoxicity in neurologic diseases
    • Beal, M.F. (1992) Mechanisms of excitotoxicity in neurologic diseases. FASEB J., 6, 3338-3344.
    • (1992) FASEB J , vol.6 , pp. 3338-3344
    • Beal, M.F.1
  • 2
    • 46849097142 scopus 로고    scopus 로고
    • NMDA receptors in clinical neurology: excitatory times ahead
    • Kalia, L.V., Kalia, S.K. and Salter, M.W. (2008) NMDA receptors in clinical neurology: excitatory times ahead. Lancet Neurol., 7, 742-755.
    • (2008) Lancet Neurol , vol.7 , pp. 742-755
    • Kalia, L.V.1    Kalia, S.K.2    Salter, M.W.3
  • 3
    • 71849096524 scopus 로고    scopus 로고
    • Mitochondria: joining forces to thwart cell death
    • Jahani-Asl, A., Germain, M. and Slack, R.S. Mitochondria: joining forces to thwart cell death. (2010) Biochim. Biophys. Acta, 1802, 162-166.
    • (2010) Biochim. Biophys. Acta , vol.1802 , pp. 162-166
    • Jahani-Asl, A.1    Germain, M.2    Slack, R.S.3
  • 4
    • 79953019314 scopus 로고    scopus 로고
    • The mitochondrial inner membrane GTPase, optic atrophy 1 (Opa1), restores mitochondrial morphology and promotes neuronal survival following excitotoxicity
    • Jahani-Asl, A., Pilon-Larose, K., Xu, W., MacLaurin, J.G., Park, D.S., McBride, H.M. and Slack, R.S. (2011) The mitochondrial inner membrane GTPase, optic atrophy 1 (Opa1), restores mitochondrial morphology and promotes neuronal survival following excitotoxicity. J. Biol. Chem., 286, 4772-4782.
    • (2011) J. Biol. Chem , vol.286 , pp. 4772-4782
    • Jahani-Asl, A.1    Pilon-Larose, K.2    Xu, W.3    MacLaurin, J.G.4    Park, D.S.5    McBride, H.M.6    Slack, R.S.7
  • 5
    • 71849086878 scopus 로고    scopus 로고
    • The molecular mechanism and cellular functions of mitochondrial division
    • Lackner, L.L. and Nunnari, J.M. (2009) The molecular mechanism and cellular functions of mitochondrial division. Biochim. Biophy. Acta, 1792, 1138-1144.
    • (2009) Biochim. Biophy. Acta , vol.1792 , pp. 1138-1144
    • Lackner, L.L.1    Nunnari, J.M.2
  • 6
    • 56349133547 scopus 로고    scopus 로고
    • Positioning mitochondrial plasticity within cellular signaling cascades
    • Soubannier, V. and McBride, H.M. (2009) Positioning mitochondrial plasticity within cellular signaling cascades. Biochim. Biophy. Acta, 1793, 154-170.
    • (2009) Biochim. Biophy. Acta , vol.1793 , pp. 154-170
    • Soubannier, V.1    McBride, H.M.2
  • 7
    • 1542380494 scopus 로고    scopus 로고
    • Sumo1 conjugates mitochondrial substrates and participates in mitochondrial fission
    • Harder, Z., Zunino, R. and McBride, H. (2004) Sumo1 conjugates mitochondrial substrates and participates in mitochondrial fission. Curr. Biol., 14, 340-345.
    • (2004) Curr. Biol , vol.14 , pp. 340-345
    • Harder, Z.1    Zunino, R.2    McBride, H.3
  • 8
    • 34248182897 scopus 로고    scopus 로고
    • Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death
    • Wasiak, S., Zunino, R. and McBride, H.M. (2007) Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death. J. Cell Biol., 177, 439-450.
    • (2007) J. Cell Biol , vol.177 , pp. 439-450
    • Wasiak, S.1    Zunino, R.2    McBride, H.M.3
  • 9
    • 34248225298 scopus 로고    scopus 로고
    • The SUMO protease SENP5 is required to maintain mitochondrial morphology and function
    • Zunino, R., Schauss, A., Rippstein, P., Andrade-Navarro, M. and McBride, H.M. (2007) The SUMO protease SENP5 is required to maintain mitochondrial morphology and function. J. Cell Sci., 120, 1178-1188.
    • (2007) J. Cell Sci , vol.120 , pp. 1178-1188
    • Zunino, R.1    Schauss, A.2    Rippstein, P.3    Andrade-Navarro, M.4    McBride, H.M.5
  • 11
    • 34547611925 scopus 로고    scopus 로고
    • Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology
    • Chang, C.R. and Blackstone, C. (2007) Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology. J. Biol. Chem., 282, 21583-21587.
    • (2007) J. Biol. Chem , vol.282 , pp. 21583-21587
    • Chang, C.R.1    Blackstone, C.2
  • 12
    • 34848840991 scopus 로고    scopus 로고
    • Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death
    • Cribbs, J.T. and Strack, S. (2007) Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death. EMBO Rep., 8, 939-944.
    • (2007) EMBO Rep , vol.8 , pp. 939-944
    • Cribbs, J.T.1    Strack, S.2
  • 14
    • 34249689057 scopus 로고    scopus 로고
    • Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission
    • Taguchi, N., Ishihara, N., Jofuku, A., Oka, T. and Mihara, K. (2007) Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission. J. Biol. Chem., 282, 11521-11529.
    • (2007) J. Biol. Chem , vol.282 , pp. 11521-11529
    • Taguchi, N.1    Ishihara, N.2    Jofuku, A.3    Oka, T.4    Mihara, K.5
  • 16
    • 84880008164 scopus 로고    scopus 로고
    • Cyclin-dependent kinases regulate splice-specific targeting of dynamin-related protein 1 to microtubules
    • Strack, S., Wilson, T.J. and Cribbs, J.T. (2013) Cyclin-dependent kinases regulate splice-specific targeting of dynamin-related protein 1 to microtubules. J. Cell Biol., 201, 1037-1051.
    • (2013) J. Cell Biol , vol.201 , pp. 1037-1051
    • Strack, S.1    Wilson, T.J.2    Cribbs, J.T.3
  • 17
    • 10944269186 scopus 로고    scopus 로고
    • The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses
    • Li, Z., Okamoto, K., Hayashi, Y. and Sheng, M. (2004) The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. Cell, 119, 873-887.
    • (2004) Cell , vol.119 , pp. 873-887
    • Li, Z.1    Okamoto, K.2    Hayashi, Y.3    Sheng, M.4
  • 20
    • 0030694346 scopus 로고    scopus 로고
    • Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons
    • Park, D.S., Levine, B., Ferrari, G. and Greene, L.A. (1997) Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons. J. Neurosci., 17, 8975-8983.
    • (1997) J. Neurosci , vol.17 , pp. 8975-8983
    • Park, D.S.1    Levine, B.2    Ferrari, G.3    Greene, L.A.4
  • 26
  • 29
    • 56449083735 scopus 로고    scopus 로고
    • Cdk5 and the non-catalytic arrest of the neuronal cell cycle
    • Zhang, J. and Herrup, K. (2008) Cdk5 and the non-catalytic arrest of the neuronal cell cycle. Cell Cycle, 7, 3487-3490.
    • (2008) Cell Cycle , vol.7 , pp. 3487-3490
    • Zhang, J.1    Herrup, K.2
  • 30
    • 77955735085 scopus 로고    scopus 로고
    • Cdk5: Links to DNA damage
    • Huang, E., Qu, D. and Park, D.S. (2010) Cdk5: Links to DNA damage. Cell Cycle, 9, 3142-3143.
    • (2010) Cell Cycle , vol.9 , pp. 3142-3143
    • Huang, E.1    Qu, D.2    Park, D.S.3
  • 31
    • 54349117421 scopus 로고    scopus 로고
    • Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicity
    • Maestre, C., Delgado-Esteban, M., Gomez-Sanchez, J.C., Bolanos, J.P. and Almeida, A. (2008) Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicity. EMBO J., 27, 2736-2745.
    • (2008) EMBO J , vol.27 , pp. 2736-2745
    • Maestre, C.1    Delgado-Esteban, M.2    Gomez-Sanchez, J.C.3    Bolanos, J.P.4    Almeida, A.5
  • 32
    • 32544441845 scopus 로고    scopus 로고
    • Calpain-regulated p35/cdk5 plays a central role in dopaminergic neuron death through modulation of the transcription factor myocyte enhancer factor 2
    • Smith, P.D., Mount, M.P., Shree, R., Callaghan, S., Slack, R.S., Anisman, H., Vincent, I., Wang, X., Mao, Z. and Park, D.S. (2006) Calpain-regulated p35/cdk5 plays a central role in dopaminergic neuron death through modulation of the transcription factor myocyte enhancer factor 2. J. Neurosci., 26, 440-447.
    • (2006) J. Neurosci , vol.26 , pp. 440-447
    • Smith, P.D.1    Mount, M.P.2    Shree, R.3    Callaghan, S.4    Slack, R.S.5    Anisman, H.6    Vincent, I.7    Wang, X.8    Mao, Z.9    Park, D.S.10
  • 40
    • 0030884275 scopus 로고    scopus 로고
    • A dual-specificity phosphatase Cdc25B is an unstable protein and triggers p34(cdc2)/cyclin B activation in hamster BHK21 cells arrested with hydroxyurea
    • Nishijima, H., Nishitani, H., Seki, T. and Nishimoto, T. (1997) A dual-specificity phosphatase Cdc25B is an unstable protein and triggers p34(cdc2)/cyclin B activation in hamster BHK21 cells arrested with hydroxyurea. J. Cell Biol., 138, 1105-1116.
    • (1997) J. Cell Biol , vol.138 , pp. 1105-1116
    • Nishijima, H.1    Nishitani, H.2    Seki, T.3    Nishimoto, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.