Regulation and role of neuroglobin and cytoglobin under hypoxia

Advances in Experimental Medicine and Biology

Volumn 618, Issue , 2007, Pages 169-180

  Burmester, Thorsten ^a   Gerlach, Frank ^a,b   Hankeln, Thomas ^b  

^a UNIVERSITY OF HAMBURG   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Gene regulation; Globin; Ischemia; Mitochondria; Reactive oxygen species

Indexed keywords

COLLAGEN; CYTOGLOBIN; MYOGLOBIN; NEUROGLOBIN; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE;

CELL CULTURE; CELL POPULATION; CELL PROLIFERATION; CELL TYPE; COLLAGEN SYNTHESIS; CONFERENCE PAPER; ELECTRIC POTENTIAL; FIBROBLAST; HYPOXIA; NERVE CELL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RESPIRATORY CHAIN;

CARASSIUS AURATUS; DANIO RERIO; MAMMALIA; RATTUS; RODENTIA; SPALAX; TESTUDINES; VERTEBRATA;

ANIMALS; ANOXIA; CELL PROLIFERATION; CELL RESPIRATION; GLOBINS; HUMANS; NERVE TISSUE PROTEINS; NITRIC OXIDE; TISSUE DISTRIBUTION;

EID: 58249102180     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-0-387-75434-5_13     Document Type: Conference Paper

References (33)

1. Bentmann A, Schmidt M, Reuss S, Wolfrum U, Hankeln T, and Burmester T. Divergent distribution in vascular and avascular mammalian retinae links neuroglobin to cellular respiration. J Biol Chem 280: 20660-20665, 2005.
2. Brunori M, Giuffre A, Nienhaus K, Nienhaus GU, Scandurra FM, and Vallone B. Neuroglobin, nitric oxide, and oxygen: functional pathways and conformational changes. Proc Natl Acad Sci USA 102: 8483-8488, 2005.
3. Burmester T, Weich B, Reinhardt S, and Hankeln T. A vertebrate globin expressed in the brain. Nature 407: 520-523, 2000.
4. Burmester T, Ebner B, Weich B, and Hankeln T. Cytoglobin: a novel globin type ubiquitously expressed in vertebrate tissues. Mol Biol Evol 19: 416-421, 2002.
5. Fago A, Mathews AJ, Dewilde S, Moens L, and Brittain T. The reactions of neuroglobin with CO: evidence for two forms of the ferrous protein. J Inorg Biochem 100: 1339-1343, 2006.
6. Fordel E, Geuens E, Dewilde S, Rottiers P, Carmeliet P, Grooten J, and Moens L. Cytoglobin expression is upregulated in all tissues upon hypoxia: an in vitro and in vivo study by quantitative real-time PCR. Biochem Biophys Res Commun 319: 342-348, 2004.
7. Fordel E, Thijs L, Martinet W, Lenjou M, Laufs T, Van Bockstaele D, Moens L, and Dewilde S. Neuroglobin and cytoglobin overexpression protects human SH-SY5Y neuroblastoma cells against oxidative stress-induced cell death. Neurosci Lett 410: 146-151, 2006.
8. Fordel E, Thijs L, Moens L, and Dewilde S. Neuroglobin and cytoglobin expression in mice. FEBS J 274: 1312-1317, 2007.
9. Halliwell B. Oxidative stress and neurodegeneration: where are we now? J Neuchem 97: 1634-1658, 2006.
10. Hankeln T, Ebner B, Fuchs C, Gerlach F, Haberkamp M, Laufs TL, Roesner A, Schmidt M, Weich B, Wystub S, Saaler-Reinhardt S, Reuss S, Bolognesi M, De Sanctis D, Marden MC, Kiger L, Moens L, Dewilde S, Nevo E, Avivi A, Weber RE, Fago A, and Burmester T. Neuroglobin and cytoglobin in search of their role in the vertebrate globin family. J Inorg Biochem 99: 110-119, 2005
11. Hundahl C, Stoltenberg M, Fago A, Weber RE, Dewilde S, Fordel E, and Danscher G. Effects of short-term hypoxia on neuroglobin levels and localization in mouse brain tissues. Neuropathol Appl Neurobiol 31: 610-617, 2005.
12. Hundahl C, Kelsen J, Kjaer K, Ronn LC, Weber RE, Geuens E, Hay-Schmidt A, and Nyengaard JR. Does neuroglobin protect neurons from ischemic insult? A quantitative investigation of neuroglobin expression following transient MCAo in spontaneously hypertensive rats. Brain Res 1085: 19-27, 2006.
13. Khan AA, Wang Y, Sun Y, Mao XO, Xie L, Miles E, Graboski J, Chen S, Ellerby LM, Jin K, and Greenberg DA. Neuroglobin-overexpressing transgenic mice are resistant to cerebral and myocardial ischemia. Proc Natl Acad Sci USA 103: 17944-17948, 2006.
14. Li RC, Lee SK, Pouranfar F, Brittian KR, Clair HB, Row BW, Wang Y, and Gozal D. Hypoxia differentially regulates the expression of neuroglobin and cytoglobin in rat brain. Brain Res 1096: 173-179, 2006.
15. Mammen PPA, Shelton JM, Goetsch SC, Williams SC, Richardson, JA Garry MG, and Garry DJ. Neuroglobin, a novel member of the globin family, is expressed in focal regions of the brain. J Histochem Cytochem 50: 1591-1598, 2002.
16. Mammen PP, Shelton JM, Ye Q, Kanatous SB, McGrath AJ, Richardson JA, and Garry DJ. Cytoglobin is a stress-responsive hemoprotein expressed in the developing and adult brain. J Histochem Cytochem 54:1349-1361, 2006.
17. Mendoza V, Klein D, Ichii H, Ribeiro MM, Ricordi C, Hankeln T, Burmester T, Pastori RL. Protection of islets in culture by delivery of oxygen binding neuroglobin via protein transduction. Transplant Proc 37: 237-240, 2005.
18. Milton SL, Nayak G, Lutz PL, and Prentice HM. Gene transcription of neuroglobin is upregulated by hypoxia and anoxia in the brain of the anoxia-tolerant turtle Trachemys scripta. J Biomed Sci 13: 509-514, 2006.
19. Nakatani K, Okuyama H, Shimahara Y, Saeki S, Kim DH, Nakajima Y, Seki S, Kawada N, and Yoshizato K. Cytoglobin/STAP, its unique localization in splanchnic fibroblast-like cells and function in organ fibrogenesis. Lab Invest 84: 91-101, 2004.
20. Rayner BS, Duong TT, Myers SJ, and Witting PK. Protective effect of a synthetic anti-oxidant on neuronal cell apoptosis resulting from experimental hypoxia reoxygenation injury. J Neurochem 97: 211-221, 2006.
21. Reuss S, Saaler-Reinhardt S, Weich B, Wystub S, Reuss M, Burmester T, and Hankeln T. Expression analysis of neuroglobin mRNA in rodent tissues. Neuroscience 115: 645-656, 2002.
22. Roesner A, Hankeln T, and Burmester T. Hypoxia induces a complex response of globin expression in zebrafish (Danio rerio). J Exp Biol 209: 2129-2137, 2006.
23. Schmidt M, Gießl A, Laufs T, Hankeln T, Wolfrum U, and Burmester T. How does the eye breathe? Evidence for neuroglobin-mediated oxygen supply of the mammalian retina. J Biol Chem 278: 1932-1935, 2003.
24. Schmidt M, Gerlach F, Avivi A, Laufs T, Wystub S, Simpson JC, Nevo E, Saaler-Reinhardt S, Reuss S, Hankeln T, and Burmester T. Cytoglobin is a respiratory protein expressed in connective tissue and neurons that is up-regulated by hypoxia. J Biol Chem 279: 8063-8069, 2004.
25. Schmidt M, Laufs T, Reuss S, Hankeln T, and Burmester T. Divergent distribution of cytoglobin and neuroglobin in the murine eye. Neurosci Lett 374: 207-211, 2005.
26. Schmidt-Kastner R, Haberkamp M, Schmitz C, Hankeln T, and Burmester T. Neuroglobin mRNA expression after transient global brain ischemia and prolonged hypoxia in cell culture. Brain Res 1103: 173-180, 2006
27. Shang A, Zhou D, Wang L, Gao Y, Fan M, Wang X, Zhou R, and Zhang C. Increased neuroglobin levels in the cerebral cortex and serum after ischemia-reperfusion insults. Brain Res 1078: 219-226, 2006.
28. Stagner JI, Parthasarathy SN, Wyler K, and Parthasarathy RN. Protection from ischemic cell death by the induction of cytoglobin. Transplant Proc 37: 3452-3453, 2005.
29. Sun Y, Jin K, Mao XO, Zhu Y, and Greenberg DA. Neuroglobin is up-regulated by and protects neurons from hypoxic-ischemic injury. Proc Natl Acad Sci USA 98: 15306-15311, 2001.
30. Sun Y, Jin K, Peel A, Mao XO, Xie L, and Greenberg DA. Neuroglobin protects the brain from experimental stroke in vivo. Proc Natl Acad Sci USA 100: 3497-3500, 2003.
31. Wittenberg JB, and Wittenberg BA. Myoglobin function reassessed. J Exp Biol 206: 2011-2020, 2003.
32. Wystub S, Ebner B, Fuchs C, Weich B, Burmester T, and Hankeln T. Interspecies comparison of neuroglobin, cytoglobin and myoglobin: sequence evolution and candidate regulatory elements. Cytogenet Genome Res 105: 65-78, 2004.
33. Zhu Y, Sun Y, Jin K, and Greenberg DA. Hemin induces neuroglobin expression in neural cells. Blood 100: 2494-2498, 2002.