Molecular and Morphological Characterization of Inflammatory Infiltrate in Rosacea Reveals Activation of Th1/Th17 Pathways

Journal of Investigative Dermatology

Volumn 135, Issue 9, 2015, Pages 2198-2208

  Buhl, Timo ^a,b,c   Sulk, Mathias ^c,d   Nowak, Pawel ^d   Buddenkotte, Jörg ^d   McDonald, Ian ^b   Aubert, Jérôme ^e   Carlavan, Isabelle ^e   Déret, Sophie ^e   Reiniche, Pascale ^e   Rivier, Michel ^e   Voegel, Johannes J ^e   Steinhoff, Martin ^b,c,f  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF MÜNSTER   (Germany)

^e Galderma R and D   (France)

^f UNIVERSITY OF SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE; CD14 ANTIGEN; CD163 ANTIGEN; CD18 ANTIGEN; CD68 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CXCR4; CXCL1 CHEMOKINE; CXCL11 CHEMOKINE; CXCL13 CHEMOKINE; CXCL2 CHEMOKINE; CXCL9 CHEMOKINE; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE CHEMOTACTIC PROTEIN 2; INTEGRIN; INTEGRIN ALPHA M; INTERLEUKIN 17; INTERLEUKIN 22; INTERLEUKIN 26; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MONOCYTE CHEMOTACTIC PROTEIN 2; RANTES; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 4; TRANSCRIPTOME; UNCLASSIFIED DRUG; CHEMOKINE;

ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; ERYTHEMATOTELANGIECTATIC ROSACEA; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATORY INFILTRATE; MACROPHAGE; MAST CELL; NEUTROPHIL; PAPULOPUSTULAR ROSACEA; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ROSACEA; SKIN BIOPSY; SKIN INFILTRATE; T LYMPHOCYTE; TH1 CELL; TH17 CELL; TRANSCRIPTOMICS; UPREGULATION; ADAPTIVE IMMUNITY; ADULT; CASE CONTROL STUDY; CELL PROLIFERATION; COMPARATIVE STUDY; FEMALE; IMMUNOLOGY; INFLAMMATION; MALE; METABOLISM; MIDDLE AGED; MOLECULARLY TARGETED THERAPY; NEEDLE BIOPSY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; REFERENCE VALUE;

ADAPTIVE IMMUNITY; ADULT; BIOPSY, NEEDLE; CASE-CONTROL STUDIES; CELL PROLIFERATION; CHEMOKINES; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MACROPHAGES; MALE; MAST CELLS; MIDDLE AGED; MOLECULAR TARGETED THERAPY; REFERENCE VALUES; ROSACEA; TH1 CELLS; TH17 CELLS;

EID: 84939472867     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2015.141     Document Type: Article

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