FTO-dependent function of N6-methyladenosine is involved in the hepatoprotective effects of betaine on adolescent mice

Journal of Physiology and Biochemistry

Volumn 71, Issue 3, 2015, Pages 405-413

  Chen, Jingqing ^a   Zhou, Xihong ^a,b   Wu, Weiche ^a   Wang, Xinxia ^a   Wang, Yizhen ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Adolescence; Betaine; FTO; Methylation; N6 methyladenosine

Indexed keywords

6 N METHYLADENOSINE; ACETYL COENZYME A CARBOXYLASE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BETAINE; CARNITINE PALMITOYLTRANSFERASE I; FATTY ACID; FATTY ACID SYNTHASE; MESSENGER RNA; ADENOSINE; CHOLESTEROL; FTO PROTEIN, MOUSE; GLUCOSE BLOOD LEVEL; LYASE; MIXED FUNCTION OXIDASE; N(6)-METHYLADENOSINE;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY WEIGHT; CONTROLLED STUDY; DEMETHYLATION; DIET SUPPLEMENTATION; DOWN REGULATION; FAT MASS; FATTY ACID OXIDATION; FEMALE; FTO GENE; GENE; LIPID METABOLISM; LIPOGENESIS; LIPOLYSIS; LIVER FUNCTION; LIVER PROTECTION; MALE; MITOCHONDRION; MORPHOLOGY; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA METHYLATION; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN; ADVERSE EFFECTS; ANALOGS AND DERIVATIVES; ANIMAL; BLOOD; C57BL MOUSE; CELL PROTECTION; DRUG EFFECTS; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; LIPID DIET; LIVER; LIVER CELL; METABOLISM; METHYLATION; NON-ALCOHOLIC FATTY LIVER DISEASE; PATHOLOGY; PHYSIOLOGY; PRECLINICAL STUDY; RNA PROCESSING;

MUS;

ADENOSINE; ANIMALS; BETAINE; BLOOD GLUCOSE; CHOLESTEROL; CYTOPROTECTION; DIET, HIGH-FAT; DRUG EVALUATION, PRECLINICAL; FEMALE; GENE EXPRESSION; HEPATOCYTES; LIPID METABOLISM; LIVER; METHYLATION; MICE, INBRED C57BL; MIXED FUNCTION OXYGENASES; NON-ALCOHOLIC FATTY LIVER DISEASE; OXO-ACID-LYASES; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; WEIGHT GAIN;

EID: 84939469229     PISSN: 11387548     EISSN: 18778755     Source Type: Journal    
DOI: 10.1007/s13105-015-0420-1     Document Type: Article

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