Betaine supplementation causes increase in carnitine metabolites in the muscle and liver of mice fed a high-fat diet as studied by nontargeted LC-MS metabolomics approach

Molecular Nutrition and Food Research

Volumn 57, Issue 11, 2013, Pages 1959-1968

  Pekkinen, Jenna ^a   Olli, Kaisa ^b   Huotari, Anne ^a   Tiihonen, Kirsti ^b   Keski Rahkonen, Pekka ^a   Lehtonen, Marko ^a   Auriola, Seppo ^a   Kolehmainen, Marjukka ^a   Mykkänen, Hannu ^a   Poutanen, Kaisa ^a,c   Hanhineva, Kati ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b DUPONT COMPANY   (United States)

^c VTT TECHNICAL RESEARCH CENTRE OF FINLAND   (Finland)

Author keywords

Betaine; Carnitine; Nontargeted metabolite profiling; Polydextrose; Tissue metabolomics

Indexed keywords

ACETYLCARNITINE; BETAINE; CARNITINE; DRUG DERIVATIVE; GAMMA BUTYROBETAINE; GAMMA-BUTYROBETAINE; GLUCAN; INSULIN; LEPTIN; POLYDEXTROSE; PROPIONYLCARNITINE; TRIACYLGLYCEROL;

ADIPOSE TISSUE; ANIMAL; ARTICLE; BLOOD; C57BL MOUSE; DIET RESTRICTION; DIET SUPPLEMENTATION; DRUG EFFECT; GLUCOSE BLOOD LEVEL; LIPID DIET; LIPID METABOLISM; LIQUID CHROMATOGRAPHY; LIVER; MALE; MASS SPECTROMETRY; METABOLISM; METABOLOMICS; METHODOLOGY; MOUSE; NONTARGETED METABOLITE PROFILING; OBESITY; SKELETAL MUSCLE; TISSUE METABOLOMICS; WEIGHT GAIN;

BETAINE; CARNITINE; NONTARGETED METABOLITE PROFILING; POLYDEXTROSE; TISSUE METABOLOMICS;

ACETYLCARNITINE; ADIPOSE TISSUE; ADIPOSITY; ANIMALS; BETAINE; BLOOD GLUCOSE; CARNITINE; CHROMATOGRAPHY, LIQUID; DIET, HIGH-FAT; DIETARY SUPPLEMENTS; FASTING; GLUCANS; INSULIN; LEPTIN; LIPID METABOLISM; LIVER; MALE; MASS SPECTROMETRY; METABOLOMICS; MICE; MICE, INBRED C57BL; MUSCLE, SKELETAL; OBESITY; TRIGLYCERIDES; WEIGHT GAIN;

EID: 84886793536     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201300142     Document Type: Article

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