Differential regulation of mGlu5R and ΜoPr by priming- and cue-induced reinstatement of cocaine-seeking behaviour in mice

Addiction Biology

Volumn 20, Issue 5, 2015, Pages 902-912

  Georgiou, Polymnia ^a   Zanos, Panos ^a   Ehteramyan, Mazdak ^b   Hourani, Susanna ^a   Kitchen, Ian ^a   Maldonado, Rafael ^b   Bailey, Alexis ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

^b UNIVERSITAT POMPEU FABRA   (Spain)

Author keywords

Cocaine; mGlu5; opioid; oxytocin; relapse; self administration

Indexed keywords

COCAINE; KAPPA OPIATE RECEPTOR; METABOTROPIC RECEPTOR 5; MU OPIATE RECEPTOR; OXYTOCIN RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; AUTORADIOGRAPHY; BASOLATERAL AMYGDALA; CENTRAL NUCLEUS (AMYGDALA); COCAINE DEPENDENCE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG SEEKING BEHAVIOR; ENZYME REGULATION; MALE; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PUTAMEN; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; REINSTATEMENT OF COCAINE SEEKING BEHAVIOR; SELF ADMINISTRATION TEST; SEPTUM PELLUCIDUM; UPREGULATION; ANIMAL; ANIMAL BEHAVIOR; ASSOCIATION; BRAIN; DISEASE MODEL; DRUG EFFECTS; DRUG SELF ADMINISTRATION; INSTRUMENTAL CONDITIONING; METABOLISM; PHYSIOLOGY; RECURRENT DISEASE;

ANIMALS; AUTORADIOGRAPHY; BEHAVIOR, ANIMAL; BRAIN; COCAINE-RELATED DISORDERS; CONDITIONING, OPERANT; CUES; DISEASE MODELS, ANIMAL; MALE; MICE; RECEPTOR, METABOTROPIC GLUTAMATE 5; RECEPTORS, OPIOID, MU; RECURRENCE; SELF ADMINISTRATION; UP-REGULATION;

EID: 84939267653     PISSN: 13556215     EISSN: 13691600     Source Type: Journal    
DOI: 10.1111/adb.12208     Document Type: Article

References (47)

1. Al-Hasani R, McCall JG, Foshage AM, Bruchas MR, (2013) Locus coeruleus kappa-opioid receptors modulate reinstatement of cocaine place preference through a noradrenergic mechanism. Neuropsychopharmacology 38: 2484-2497.
2. Aldrich JV, Senadheera SN, Ross NC, Ganno ML, Eans SO, McLaughlin JP, (2013) The macrocyclic peptide natural product CJ-15,208 is orally active and prevents reinstatement of extinguished cocaine-seeking behavior. J Nat Prod 76: 433-438.
3. Backstrom P, Hyytia P, (2006) Ionotropic and metabotropic glutamate receptor antagonism attenuates cue-induced cocaine seeking. Neuropsychopharmacology 31: 778-786.
4. Bailey A, Gianotti R, Ho A, Kreek MJ, (2005) Persistent upregulation of mu-opioid, but not adenosine, receptors in brains of long-term withdrawn escalating dose 'binge' cocaine-treated rats. Synapse 57: 160-166.
5. Bailey A, Gianotti R, Ho A, Kreek MJ, (2007a) Downregulation of kappa-opioid receptors in basolateral amygdala and septum of rats withdrawn for 14 days from an escalating dose 'binge' cocaine administration paradigm. Synapse 61: 820-826.
6. Bailey A, Yoo JH, Racz I, Zimmer A, Kitchen I, (2007b) Preprodynorphin mediates locomotion and D2 dopamine and mu-opioid receptor changes induced by chronic 'binge' cocaine administration. J Neurochem 102: 1817-1830.
7. Bossert JM, Marchant NJ, Calu DJ, Shaham Y, (2013) The reinstatement model of drug relapse: recent neurobiological findings, emerging research topics, and translational research. Psychopharmacology (Berl) 229: 453-476.
8. Broadbear JH, Tunstall B, Beringer K, (2011) Examining the role of oxytocin in the interoceptive effects of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') using a drug discrimination paradigm in the rat. Addict Biol 16: 202-214.
9. Carey AN, Borozny K, Aldrich JV, McLaughlin JP, (2007) Reinstatement of cocaine place-conditioning prevented by the peptide kappa-opioid receptor antagonist arodyn. Eur J Pharmacol 569: 84-89.
10. Carson DS, Cornish JL, Guastella AJ, Hunt GE, McGregor IS, (2010) Oxytocin decreases methamphetamine self-administration, methamphetamine hyperactivity, and relapse to methamphetamine-seeking behaviour in rats. Neuropharmacology 58: 38-43.
11. EMCDDA (2014) European Drug Report 2014: Trends and Developments. Lisbon.
12. Franklin KBJ, Paxinos G, (2001) The Mouse Brain in Stereotaxic Coordinates: San Diego, CA: Academic Press.
13. Gorelick DA, Kim YK, Bencherif B, Boyd SJ, Nelson R, Copersino ML, Dannals RF, Frost JJ, (2008) Brain mu-opioid receptor binding: relationship to relapse to cocaine use after monitored abstinence. Psychopharmacology (Berl) 200: 475-486.
14. Graziane NM, Polter AM, Briand LA, Pierce RC, Kauer JA, (2013) Kappa opioid receptors regulate stress-induced cocaine seeking and synaptic plasticity. Neuron 77: 942-954.
15. Hao Y, Martin-Fardon R, Weiss F, (2010) Behavioral and functional evidence of metabotropic glutamate receptor 2/3 and metabotropic glutamate receptor 5 dysregulation in cocaine-escalated rats: factor in the transition to dependence. Biol Psychiatry 68: 240-248.
16. Hurd YL, Herkenham M, (1993) Molecular alterations in the neostriatum of human cocaine addicts. Synapse 13: 357-369.
17. Johns JM, Lubin DA, Walker CH, Joyner P, Middleton C, Hofler V, McMurray M, (2004) Gestational treatment with cocaine and fluoxetine alters oxytocin receptor number and binding affinity in lactating rat dams. Int J Dev Neurosci 22: 321-328.
18. Kalivas PW, (2009) The glutamate homeostasis hypothesis of addiction. Nat Rev Neurosci 10: 561-572.
19. Kitchen I, Slowe SJ, Matthes HW, Kieffer B, (1997) Quantitative autoradiographic mapping of mu-, delta- and kappa-opioid receptors in knockout mice lacking the mu-opioid receptor gene. Brain Res 778: 73-88.
20. Kumaresan V, Yuan M, Yee J, Famous KR, Anderson SM, Schmidt HD, Pierce RC, (2009) Metabotropic glutamate receptor 5 (mGluR5) antagonists attenuate cocaine priming- and cue-induced reinstatement of cocaine seeking. Behav Brain Res 202: 238-244.
21. Le Moal M, Koob GF, (2007) Drug addiction: pathways to the disease and pathophysiological perspectives. Eur Neuropsychopharmacol 17: 377-393.
22. Markou A, Arroyo M, Everitt BJ, (1999) Effects of contingent and non-contingent cocaine on drug-seeking behavior measured using a second-order schedule of cocaine reinforcement in rats. Neuropsychopharmacology 20: 542-555.
23. Martin-Fardon R, Baptista MA, Dayas CV, Weiss F, (2009) Dissociation of the effects of MTEP [3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]piperidine] on conditioned reinstatement and reinforcement: comparison between cocaine and a conventional reinforcer. J Pharmacol Exp Ther 329: 1084-1090.
24. McGregor IS, Bowen MT, (2012) Breaking the loop: oxytocin as a potential treatment for drug addiction. Horm Behav 61: 331-339.
25. Metaxas A, Bailey A, Barbano MF, Galeote L, Maldonado R, Kitchen I, (2010) Differential region-specific regulation of α4β2∗ nAChRs by self-administered and non-contingent nicotine in C57BL/6J mice. Addict Biol 15: 464-479.
26. Nock B, Rajpara A, O'Connor LH, Cicero TJ, (1988) Autoradiography of [3H]U-69593 binding sites in rat brain: evidence for kappa opioid receptor subtypes. Eur J Pharmacol 154: 27-34.
27. Novak M, Halbout B, O'Connor EC, Rodriguez Parkitna J, Su T, Chai M, Crombag HS, Bilbao A, Spanagel R, Stephens DN, Schutz G, Engblom D, (2010) Incentive learning underlying cocaine-seeking requires mGluR5 receptors located on dopamine D1 receptor-expressing neurons. J Neurosci 30: 11973-11982.
28. O'Brien CP, (2005) Anticraving medications for relapse prevention: a possible new class of psychoactive medications. Am J Psychiatry 162: 1423-1431.
29. Qi J, Yang JY, Wang F, Zhao YN, Song M, Wu CF, (2009) Effects of oxytocin on methamphetamine-induced conditioned place preference and the possible role of glutamatergic neurotransmission in the medial prefrontal cortex of mice in reinstatement. Neuropharmacology 56: 856-865.
30. Redila VA, Chavkin C, (2008) Stress-induced reinstatement of cocaine seeking is mediated by the kappa opioid system. Psychopharmacology (Berl) 200: 59-70.
31. Sarnyai Z, (2011) Oxytocin as a potential mediator and modulator of drug addiction. Addict Biol 16: 199-201.
32. Sarnyai Z, Vecsernyes M, Laczi F, Biro E, Szabo G, Kovacs GL, (1992) Effects of cocaine on the contents of neurohypophyseal hormones in the plasma and in different brain structures in rats. Neuropeptides 23: 27-31.
33. Schmidt HD, Kimmey BA, Arreola AC, Pierce RC, (2014) Group I metabotropic glutamate receptor-mediated activation of PKC gamma in the nucleus accumbens core promotes the reinstatement of cocaine seeking. Addict Biol doi: 10.1111/adb.12122.
34. Schroeder JA, Niculescu M, Unterwald EM, (2003) Cocaine alters mu but not delta or kappa opioid receptor-stimulated in situ [35S]GTPgammaS binding in rat brain. Synapse 47: 26-32.
35. Shaham Y, Shalev U, Lu L, De Wit H, Stewart J, (2003) The reinstatement model of drug relapse: history, methodology and major findings. Psychopharmacology (Berl) 168: 3-20.
36. Sharpe LG, Pilotte NS, Shippenberg TS, Goodman CB, London ED, (2000) Autoradiographic evidence that prolonged withdrawal from intermittent cocaine reduces mu-opioid receptor expression in limbic regions of the rat brain. Synapse 37: 292-297.
37. Simmons D, Self DW, (2009) Role of mu- and delta-opioid receptors in the nucleus accumbens in cocaine-seeking behavior. Neuropsychopharmacology 34: 1946-1957.
38. Soderman AR, Unterwald EM, (2009) Cocaine-induced mu opioid receptor occupancy within the striatum is mediated by dopamine D2 receptors. Brain Res 1296: 63-71.
39. Soria G, Barbano MF, Maldonado R, Valverde O, (2008) A reliable method to study cue-, priming-, and stress-induced reinstatement of cocaine self-administration in mice. Psychopharmacology (Berl) 199: 593-603.
40. Tang XC, McFarland K, Cagle S, Kalivas PW, (2005) Cocaine-induced reinstatement requires endogenous stimulation of mu-opioid receptors in the ventral pallidum. J Neurosci 25: 4512-4520.
41. Valdez GR, Platt DM, Rowlett JK, Ruedi-Bettschen D, Spealman RD, (2007) Kappa agonist-induced reinstatement of cocaine seeking in squirrel monkeys: a role for opioid and stress-related mechanisms. J Pharmacol Exp Ther 323: 525-533.
42. Wang X, Moussawi K, Knackstedt L, Shen H, Kalivas PW, (2013) Role of mGluR5 neurotransmission in reinstated cocaine-seeking. Addict Biol 18: 40-49.
43. Ward HG, Nicklous DM, Aloyo VJ, Simansky KJ, (2006) Mu-opioid receptor cellular function in the nucleus accumbens is essential for hedonically driven eating. Eur J Neurosci 23: 1605-1613.
44. Yoo JH, Kitchen I, Bailey A, (2012) The endogenous opioid system in cocaine addiction: what lessons have opioid peptide and receptor knockout mice taught us? Br J Pharmacol 166: 1993-2014.
45. Zanos P, Georgiou P, Wright SR, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A, (2014a) The oxytocin analogue carbetocin prevents emotional impairment and stress-induced reinstatement of opioid-seeking in morphine-abstinent mice. Neuropsychopharmacology 39: 855-865.
46. Zanos P, Wright SR, Georgiou P, Yoo JH, Ledent C, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A, (2014b) Chronic methamphetamine treatment induces oxytocin receptor up-regulation in the amygdala and hypothalamus via an adenosine A2A receptor-independent mechanism. Pharmacol Biochem Behav 119: 72-79.
47. Ziolkowska B, Kielbinski M, Gieryk A, Soria G, Maldonado R, Przewlocki R, (2011) Regulation of the immediate-early genes arc and zif268 in a mouse operant model of cocaine seeking reinstatement. J Neural Transm 118: 877-887.