Angiopoietin-1 regulates brain endothelial permeability through PTPN-2 mediated tyrosine dephosphorylation of occludin

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Siddiqui, M Rizwan ^a   Mayanil, Chandra S ^a   Kim, Kwang Sik ^b   Tomita, Tadanori ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 2; OCCLUDIN; PROTEIN ZO1; SMALL INTERFERING RNA; THROMBIN; TIGHT JUNCTION PROTEIN;

ARTICLE; BLOOD BRAIN BARRIER; CELL FRACTIONATION; CELL ISOLATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; IN VITRO STUDY; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; WESTERN BLOTTING; BRAIN; CAPILLARY PERMEABILITY; CELL JUNCTION; CELL MEMBRANE; DRUG EFFECTS; GENE DELETION; GENE EXPRESSION; GENETICS; METABOLISM; PHOSPHORYLATION; PROTEIN TRANSPORT;

ANGIOPOIETIN-1; BLOOD-BRAIN BARRIER; BRAIN; CAPILLARY PERMEABILITY; CELL MEMBRANE; ENDOTHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE DELETION; GENE EXPRESSION; HUMANS; INTERCELLULAR JUNCTIONS; OCCLUDIN; PHOSPHORYLATION; PROTEIN TRANSPORT; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 2; RECEPTOR, TIE-2; THROMBIN; TIGHT JUNCTION PROTEINS; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84939249076     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0130857     Document Type: Article

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