-
1
-
-
84904742368
-
Beyond intestinal soap-bile acids in metabolic control
-
PMID: 24821328
-
Kuipers F, Bloks VW, Groen AK. Beyond intestinal soap-bile acids in metabolic control. Nat Rev Endocrinol. 2014; 10:488-498. doi:10.1038/nrendo.2014.60 PMID: 24821328.
-
(2014)
Nat Rev Endocrinol
, vol.10
, pp. 488-498
-
-
Kuipers, F.1
Bloks, V.W.2
Groen, A.K.3
-
2
-
-
84877581095
-
Pleiotropic roles of bile acids in metabolism
-
PMID: 23602448
-
de Aguiar Vallim TQ, Tarling EJ, Edwards PA. Pleiotropic roles of bile acids in metabolism. Cell Metab. 2013; 17:657-669. doi:10.1016/j.cmet.2013.03.013 PMID: 23602448.
-
(2013)
Cell Metab
, vol.17
, pp. 657-669
-
-
De Aguiar Vallim, T.Q.1
Tarling, E.J.2
Edwards, P.A.3
-
3
-
-
0003269455
-
A G protein-coupled receptor responsive to bile acids
-
PMID: 12524422
-
Kawamata Y, Fujii R, Hosoya M, Harada M, Yoshida H, Miwa M, et al. A G protein-coupled receptor responsive to bile acids. J Biol Chem 2003; 278:9435-9440. PMID: 12524422.
-
(2003)
J Biol Chem
, vol.278
, pp. 9435-9440
-
-
Kawamata, Y.1
Fujii, R.2
Hosoya, M.3
Harada, M.4
Yoshida, H.5
Miwa, M.6
-
4
-
-
33947383769
-
The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells
-
Keitel V, Reinehr R, Gatsios P, Rupprecht C, Gorg B, Selbach O, et al. The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells. Hepatology 2003; 45:695-704.
-
(2003)
Hepatology
, vol.45
, pp. 695-704
-
-
Keitel, V.1
Reinehr, R.2
Gatsios, P.3
Rupprecht, C.4
Gorg, B.5
Selbach, O.6
-
5
-
-
33748757234
-
Targeted deletion of gpbar1 protects mice from cholesterol gallstone formation
-
PMID: 16724960
-
Vassileva G, Golovko A, Markowitz L, Abbondanzo SJ, Zeng M, Yang S, et al. Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation. Biochem J 2006; 398:423-430. PMID: 16724960.
-
(2006)
Biochem J
, vol.398
, pp. 423-430
-
-
Vassileva, G.1
Golovko, A.2
Markowitz, L.3
Abbondanzo, S.J.4
Zeng, M.5
Yang, S.6
-
6
-
-
31444454037
-
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
-
PMID: 16400329
-
Watanabe M, Houten SM, Mataki C, Christoffolete MA, Kim BW, Sato H, et al. Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature 2006; 439:484-489. PMID: 16400329.
-
(2006)
Nature
, vol.439
, pp. 484-489
-
-
Watanabe, M.1
Houten, S.M.2
Mataki, C.3
Christoffolete, M.A.4
Kim, B.W.5
Sato, H.6
-
7
-
-
69149083245
-
TGR5-mediated bile acid sensing controls glucose homeostasis
-
PMID: 19723493
-
Thomas C, Gioiello A, Noriega L, Strehle A, Oury J, Rizzo G, et al. TGR5-mediated bile acid sensing controls glucose homeostasis. Cell Metab 2009; 10:167-177. doi:10.1016/j.cmet.2009.08.001 PMID: 19723493.
-
(2009)
Cell Metab
, vol.10
, pp. 167-177
-
-
Thomas, C.1
Gioiello, A.2
Noriega, L.3
Strehle, A.4
Oury, J.5
Rizzo, G.6
-
8
-
-
33751066787
-
Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice
-
PMID: 17065403
-
Maruyama T, Tanaka K, Suzuki J, Miyoshi H, Harada N, Nakamura T, et al. Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice. J Endocrinol 2006; 191:197-205. PMID: 17065403.
-
(2006)
J Endocrinol
, vol.191
, pp. 197-205
-
-
Maruyama, T.1
Tanaka, K.2
Suzuki, J.3
Miyoshi, H.4
Harada, N.5
Nakamura, T.6
-
9
-
-
79957663467
-
The G protein-coupled bile acid receptor, TGR5, stimulates gallbladder filling
-
PMID: 21454404
-
Li T, Holmstrom SR, Kir S, Umetani M, Schmidt DR, Kliewer SA, et al. The G protein-coupled bile acid receptor, TGR5, stimulates gallbladder filling. Mol Endocrinol 2011; 25:1066-1071. doi:10.1210/me.2010-0460 PMID: 21454404.
-
(2011)
Mol Endocrinol
, vol.25
, pp. 1066-1071
-
-
Li, T.1
Holmstrom, S.R.2
Kir, S.3
Umetani, M.4
Schmidt, D.R.5
Kliewer, S.A.6
-
10
-
-
80053308007
-
The G-Protein-coupled bile acid receptor, gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light-chain enhancer of activated B cells (NF-kappaB) in mice
-
PMID: 21735468
-
Wang YD, Chen WD, Yu D, Forman BM, Huang W. The G-Protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light-chain enhancer of activated B cells (NF-kappaB) in mice. Hepatology 2011; 54:1421-1432. doi:10.1002/hep.24525 PMID: 21735468.
-
(2011)
Hepatology
, vol.54
, pp. 1421-1432
-
-
Wang, Y.D.1
Chen, W.D.2
Yu, D.3
Forman, B.M.4
Huang, W.5
-
11
-
-
82955168360
-
TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading
-
PMID: 22152303
-
Pols TW, Nomura M, Harach T, Lo Sasso G, Oosterveer MH, Thomas C, et al. TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading. Cell Metab 2011; 14:747-757. doi:10.1016/j.cmet.2011.11.006 PMID: 22152303.
-
(2011)
Cell Metab
, vol.14
, pp. 747-757
-
-
Pols, T.W.1
Nomura, M.2
Harach, T.3
Lo, S.G.4
Oosterveer, M.H.5
Thomas, C.6
-
12
-
-
79960262492
-
Management of type 2 diabetes: New and future developments in treatment
-
PMID: 21705062
-
Tahrani AA, Bailey CJ, Del Prato S, Barnett AH. Management of type 2 diabetes: New and future developments in treatment. Lancet 2011; 378:182-197. doi:10.1016/S0140-6736(11)60207-9 PMID: 21705062.
-
(2011)
Lancet
, vol.378
, pp. 182-197
-
-
Tahrani, A.A.1
Bailey, C.J.2
Del, P.S.3
Barnett, A.H.4
-
13
-
-
84858776574
-
MicroRNAs in metabolism and metabolic disorders
-
PMID: 22436747
-
Rottiers V, Naar AM. MicroRNAs in metabolism and metabolic disorders. Nat Rev Mol Cell Biol 2012; 13:239-250. doi:10.1038/nrm3313 PMID: 22436747.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 239-250
-
-
Rottiers, V.1
Naar, A.M.2
-
14
-
-
84868475728
-
MicroRNA therapeutics for cardiovascular disease: Opportunities and obstacles
-
PMID: 23080337
-
van Rooij E, Olson EN. MicroRNA therapeutics for cardiovascular disease: Opportunities and obstacles. Nat Rev Drug Discov 2012; 11:860-872. doi:10.1038/nrd3864 PMID: 23080337.
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 860-872
-
-
Van, R.E.1
Olson, E.N.2
-
15
-
-
84887046365
-
MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation
-
PMID: 24114270
-
Fu X, Jin L, Wang X, Luo A, Hu J, Zheng X, et al. MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation. Proc Natl Acad Sci U S A. 2013; 110:17892-17897. doi:10.1073/pnas.1317397110 PMID: 24114270.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 17892-17897
-
-
Fu, X.1
Jin, L.2
Wang, X.3
Luo, A.4
Hu, J.5
Zheng, X.6
-
16
-
-
84906936211
-
MIR-26a enhances miRNA biogenesis by targeting lin28B and zcchc11 to suppress tumor growth and metastasis
-
PMID: 24056962
-
Fu X, Meng Z, Liang W, Tian Y, Wang X, Han W, et al. miR-26a enhances miRNA biogenesis by targeting Lin28B and Zcchc11 to suppress tumor growth and metastasis. Oncogene. 2014; 33:4296-4306. doi:10.1038/onc.2013.385 PMID: 24056962.
-
(2014)
Oncogene
, vol.33
, pp. 4296-4306
-
-
Fu, X.1
Meng, Z.2
Liang, W.3
Tian, Y.4
Wang, X.5
Han, W.6
-
17
-
-
84930405027
-
MIR-26a regulates insulin sensitivity and metabolism of glucose and lipids
-
PMID: 25961460
-
Fu XH, Dong BN, Tian Y, Lefebvre P, Meng Z, Wang X, et al. MiR-26a regulates insulin sensitivity and metabolism of glucose and lipids. 2015. J Clin Invest. 125(6):2497-509. doi:10.1172/JCI75438 PMID: 25961460.
-
(2015)
J Clin Invest
, vol.125
, Issue.6
, pp. 2497-2509
-
-
Fu, X.H.1
Dong, B.N.2
Tian, Y.3
Lefebvre, P.4
Meng, Z.5
Wang, X.6
-
18
-
-
84899672635
-
GPBAR1/TGR5 mediates bile acid-induced cytokine expression in murine Kupffer cells
-
e93567. 0093567 PMID: 24755711
-
Lou G, Ma X, Fu X, Meng Z, Zhang W, Wang YD, et al. GPBAR1/TGR5 mediates bile acid-induced cytokine expression in murine Kupffer cells. PLoS One. 2014; 9:e93567. doi:10.1371/journal.pone 0093567 PMID: 24755711.
-
(2014)
PLoS One
, vol.9
-
-
Lou, G.1
Ma, X.2
Fu, X.3
Meng, Z.4
Zhang, W.5
Wang, Y.D.6
-
19
-
-
16644376635
-
Isolation and culture of murine macrophages
-
PMID: 15361657
-
Davies JQ, Gordon S. Isolation and culture of murine macrophages. Methods Mol Biol 2005; 290:91- 103. PMID: 15361657.
-
(2005)
Methods Mol Biol
, vol.290
, pp. 91-103
-
-
Davies, J.Q.1
Gordon, S.2
-
20
-
-
34548611093
-
Anti-hyperglycemic activity of a TGR5 agonist isolated from Olea europaea
-
PMID: 17825251
-
Sato H, Genet C, Strehle A, Thomas C, Lobstein A, Wagner A, et al. Anti-hyperglycemic activity of a TGR5 agonist isolated from Olea europaea. Biochem Biophys Res Commun. 2007; 362:793-798. PMID: 17825251.
-
(2007)
Biochem Biophys Res Commun
, vol.362
, pp. 793-798
-
-
Sato, H.1
Genet, C.2
Strehle, A.3
Thomas, C.4
Lobstein, A.5
Wagner, A.6
-
22
-
-
78649588750
-
MIR-194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in mice
-
PMID: 20979124
-
Meng Z, Fu X, Chen X, Zeng S, Tian Y, Jove R, et al. miR-194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in mice. Hepatology. 2010; 52:2148-2157. doi:10.1002/hep.23915 PMID: 20979124.
-
(2010)
Hepatology
, vol.52
, pp. 2148-2157
-
-
Meng, Z.1
Fu, X.2
Chen, X.3
Zeng, S.4
Tian, Y.5
Jove, R.6
-
23
-
-
84925500666
-
Stereoselective synthesis, biological evaluation, and modeling of novel bile acid-derived g-protein-coupled Bile acid receptor 1 (GPBAR1, TGR5) agonists
-
Yu D, Sousa KM, Mattern DL, Wagner J, Fu X, Vaidehi N, et al. Stereoselective Synthesis, Biological Evaluation, and Modeling of Novel Bile Acid-Derived G-Protein-Coupled Bile Acid Receptor 1 (GPBAR1, TGR5) Agonists. Bioorganic & Medicinal Chemistry. 2015; 23:1613-1628.
-
(2015)
Bioorganic & Medicinal Chemistry
, vol.23
, pp. 1613-1628
-
-
Yu, D.1
Sousa, K.M.2
Mattern, D.L.3
Wagner, J.4
Fu, X.5
Vaidehi, N.6
-
24
-
-
84915748816
-
TGR5 reduces macrophage migration through mTOR-induced C/EBPβ differential translation
-
PMID: 25365223
-
Perino A, Pols TW, Nomura M, Stein S, Pellicciari R, Schoonjans K. TGR5 reduces macrophage migration through mTOR-induced C/EBPβ differential translation. J Clin Invest. 2014; 124:5424-36. doi:10.1172/JCI76289 PMID: 25365223.
-
(2014)
J Clin Invest
, vol.124
, pp. 5424-5436
-
-
Perino, A.1
Pols, T.W.2
Nomura, M.3
Stein, S.4
Pellicciari, R.5
Schoonjans, K.6
-
25
-
-
80052720863
-
TGR5: A novel target for weight maintenance and glucose metabolism
-
Chen X, Lou G, Meng Z, Huang W. TGR5: A novel target for weight maintenance and glucose metabolism. Exp Diabetes Res. 2011:853501.
-
(2011)
Exp Diabetes Res
, pp. 853501
-
-
Chen, X.1
Lou, G.2
Meng, Z.3
Huang, W.4
-
26
-
-
84919634159
-
Bile acid signaling and liver regeneration
-
pii: S, 00135-7
-
Fan M, Wang X, Xu G, Yan Q, Huang W. Bile acid signaling and liver regeneration. Biochim Biophys Acta. 2014. pii: S 1874-9399(14)00135-7.
-
(2014)
Biochim Biophys Acta
, vol.14
, pp. 1874-9399
-
-
Fan, M.1
Wang, X.2
Xu, G.3
Yan, Q.4
Huang, W.5
-
27
-
-
84884982788
-
The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice
-
PMID: 23686672
-
Péan N, Doignon I, Garcin I, Besnard A, Julien B, Liu B, et al. The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice. Hepatology. 2013; 58:1451-1460. doi:10.1002/hep.26463 PMID: 23686672.
-
(2013)
Hepatology
, vol.58
, pp. 1451-1460
-
-
Péan, N.1
Doignon, I.2
Garcin, I.3
Besnard, A.4
Julien, B.5
Liu, B.6
-
28
-
-
69149083245
-
TGR5-mediated bile acid sensing controls glucose homeostasis
-
PMID: 19723493
-
Thomas C, Gioiello A, Noriega L, Strehle A, Oury J, Rizzo G, et al. TGR5-mediated bile acid sensing controls glucose homeostasis. Cell Metab. 2009; 10:167-177. doi:10.1016/j.cmet.2009.08.001 PMID: 19723493.
-
(2009)
Cell Metab
, vol.10
, pp. 167-177
-
-
Thomas, C.1
Gioiello, A.2
Noriega, L.3
Strehle, A.4
Oury, J.5
Rizzo, G.6
-
29
-
-
84861682490
-
TGR5 potentiates GLP-1 secretion in response to anionic exchange resins
-
PMID: 22666533
-
Harach T, Pols TW, Nomura M, Maida A, Watanabe M, Auwerx J, et al. TGR5 potentiates GLP-1 secretion in response to anionic exchange resins. Sci Rep. 2012; 2:430. doi:10.1038/srep00430 PMID: 22666533.
-
(2012)
Sci Rep
, vol.2
, pp. 430
-
-
Harach, T.1
Pols, T.W.2
Nomura, M.3
Maida, A.4
Watanabe, M.5
Auwerx, J.6
-
30
-
-
13944260434
-
Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes
-
PMID: 15701730
-
Baskerville S, Bartel DP. Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes. RNA 2005; 11:241-247. PMID: 15701730.
-
(2005)
RNA
, vol.11
, pp. 241-247
-
-
Baskerville, S.1
Bartel, D.P.2
-
31
-
-
77149153066
-
Structure and activity of putative intronic miRNA promoters
-
PMID: 20075166
-
Monteys AM, Spengler RM, Wan J, Tecedor L, Lennox KA, Xing Y, et al. Structure and activity of putative intronic miRNA promoters. RNA 2010; 16:495-505. doi:10.1261/rna.1731910 PMID: 20075166.
-
(2010)
RNA
, vol.16
, pp. 495-505
-
-
Monteys, A.M.1
Spengler, R.M.2
Wan, J.3
Tecedor, L.4
Lennox, K.A.5
Xing, Y.6
-
32
-
-
84855323194
-
Intronic MIR-26b controls neuronal differentiation by repressing its host transcript, ctdsp2
-
PMID: 22215807
-
Dill H, Linder B, Fehr A, Fischer U. Intronic miR-26b controls neuronal differentiation by repressing its host transcript, ctdsp2. Genes Dev 2012; 26:25-30. doi:10.1101/gad.177774.111 PMID: 22215807.
-
(2012)
Genes Dev
, vol.26
, pp. 25-30
-
-
Dill, H.1
Linder, B.2
Fehr, A.3
Fischer, U.4
|