Effects of deletion of the transcription factor Nrf2 and benzo [a]pyrene treatment on ovarian follicles and ovarian surface epithelial cells in mice

Reproductive Toxicology

Volumn 58, Issue , 2015, Pages 24-32

  Lim, Jinhwan ^a   Ortiz, Laura ^a   Nakamura, Brooke N ^a   Hoang, Yvonne D ^a   Banuelos, Jesus ^a   Flores, Victoria N ^a   Chan, Jefferson Y ^b   Luderer, Ulrike ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Benzo a pyrene; DNA adduct; NRF2; Ovarian aging; Oxidative stress; Polycyclic aromatic hydrocarbon

Indexed keywords

BENZO[A]PYRENE; TRANSCRIPTION FACTOR NRF2; ANTIOXIDANT; DNA ADDUCT; NFE2L2 PROTEIN, MOUSE; POLLUTANT;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DETOXIFICATION; DNA ADDUCT; DNA DAMAGE; EMBRYO; EPITHELIUM CELL; FEMALE; GENE DELETION; GLUTATHIONE METABOLISM; METABOLITE; MOUSE; NONHUMAN; NRF2 GENE; OVARIAN SURFACE EPITHELIAL CELL; OVARIAN TOXICITY; OVARY CELL; OVARY FOLLICLE; REPRODUCTIVE TOXICITY; SENSITIVITY ANALYSIS; ANIMAL; C57BL MOUSE; CELL AGING; DEFICIENCY; DOSE RESPONSE; DRUG EFFECTS; GENETICS; GENOTYPE; KNOCKOUT MOUSE; METABOLISM; OVARIAN RESERVE; OVARY; OXIDATIVE STRESS; PATHOLOGY; PHENOTYPE; POLLUTANT; TOXICITY;

MUS;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BENZO(A)PYRENE; CELL AGING; CELL PROLIFERATION; DNA ADDUCTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; EPITHELIAL CELLS; FEMALE; GENE DELETION; GENOTYPE; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-E2-RELATED FACTOR 2; OVARIAN FOLLICLE; OVARIAN RESERVE; OVARY; OXIDATIVE STRESS; PHENOTYPE;

EID: 84939231743     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2015.07.080     Document Type: Article

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