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Volumn 73, Issue 2, 2013, Pages 908-917

Glutathione-deficient mice have increased sensitivity to transplacental benzo[a]pyrene-induced premature ovarian failure and ovarian tumorigenesis

Author keywords

[No Author keywords available]

Indexed keywords

BENZO[A]PYRENE; CYTOKERATIN; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE;

EID: 84872527110     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-3636     Document Type: Article
Times cited : (52)

References (50)
  • 2
    • 44649103908 scopus 로고    scopus 로고
    • Concentration and profile of 22 urinary polycyclic aromatic hydrocarbon metabolites in the US population
    • Li Z, Sandau CD, Romanoff LC, Caudill SP, Sjodin A, Needham LL, et al. Concentration and profile of 22 urinary polycyclic aromatic hydrocarbon metabolites in the US population. Environ Res 2008;107: 320-31.
    • (2008) Environ Res , vol.107 , pp. 320-331
    • Li, Z.1    Sandau, C.D.2    Romanoff, L.C.3    Caudill, S.P.4    Sjodin, A.5    Needham, L.L.6
  • 3
    • 0018686309 scopus 로고
    • Difference in sensitivity of rat and mouse primordial oocytes to destruction by polycyclic aromatic hydrocarbons
    • Mattison DR. Difference in sensitivity of rat and mouse primordial oocytes to destruction by polycyclic aromatic hydrocarbons. Chem Biol Interact 1979;28: 133-7.
    • (1979) Chem Biol Interact , vol.28 , pp. 133-137
    • Mattison, D.R.1
  • 4
    • 0018650396 scopus 로고
    • Ovarian aryl hydrocarbon hydroxylase activity and primordial oocyte toxicity of polycyclic aromatic hydrocarbons in mice
    • Mattison DR, Thorgeirsson SS. Ovarian aryl hydrocarbon hydroxylase activity and primordial oocyte toxicity of polycyclic aromatic hydrocarbons in mice. Cancer Res 1979;39: 3471-5.
    • (1979) Cancer Res , vol.39 , pp. 3471-3475
    • Mattison, D.R.1    Thorgeirsson, S.S.2
  • 5
    • 0034665731 scopus 로고    scopus 로고
    • Ovotoxicity in Female fischer rats and B6 mice induced by low-dose exposure to three polycyclic aromatic hydrocarbons: Comparison through calculation of an ovotoxic index
    • Borman SM, Christian PJ, Sipes IG, Hoyer PB. Ovotoxicity in female fischer rats and B6 mice induced by low-dose exposure to three polycyclic aromatic hydrocarbons: comparison through calculation of an ovotoxic index. Toxicol Appl Pharmacol 2000;167: 191-8.
    • (2000) Toxicol Appl Pharmacol , vol.167 , pp. 191-198
    • Borman, S.M.1    Christian, P.J.2    Sipes, I.G.3    Hoyer, P.B.4
  • 6
    • 0021826953 scopus 로고
    • Cigarette smoking associated with delayed conception
    • Baird DD, Wilcox AJ. Cigarette smoking associated with delayed conception. JAMA 1985;253: 2979-83.
    • (1985) JAMA , vol.253 , pp. 2979-2983
    • Baird, D.D.1    Wilcox, A.J.2
  • 7
    • 0032533208 scopus 로고    scopus 로고
    • Adult and prenatal exposures to tobacco smoke as risk indicators of fertility among 430 Danish couples
    • Jensen TK, Henriksen TB, Hjollund NH, Scheike T, Kolstad H, Giwercman A, et al. Adult and prenatal exposures to tobacco smoke as risk indicators of fertility among 430 Danish couples. Am J Epidemiol 1998;148: 992-7.
    • (1998) Am J Epidemiol , vol.148 , pp. 992-997
    • Jensen, T.K.1    Henriksen, T.B.2    Hjollund, N.H.3    Scheike, T.4    Kolstad, H.5    Giwercman, A.6
  • 8
    • 0034724908 scopus 로고    scopus 로고
    • Factors associated with early menopause
    • Harlow BL, Signorello LB. Factors associated with early menopause. Maturitas 2000;35: 3-9.
    • (2000) Maturitas , vol.35 , pp. 3-9
    • Harlow, B.L.1    Signorello, L.B.2
  • 9
    • 84966138594 scopus 로고
    • Ovarian and mammary tumours in intact C3Hb virgin mice following a limited dose of four carcinogenic chemicals
    • Biancifiori C, Bonser GM, Caschera F. Ovarian and mammary tumours in intact C3Hb virgin mice following a limited dose of four carcinogenic chemicals. Br J Cancer 1961;15: 270-83.
    • (1961) Br J Cancer , vol.15 , pp. 270-283
    • Biancifiori, C.1    Bonser, G.M.2    Caschera, F.3
  • 10
    • 0014038675 scopus 로고
    • 9: 10-Dimethyl-1: 2-benzanthracene induced ovarian tumours in mice
    • Krarup T. 9: 10-Dimethyl-1: 2-benzanthracene induced ovarian tumours in mice. Acta Pathol Microbiol Scand 1967;70: 241-8.
    • (1967) Acta Pathol Microbiol Scand , vol.70 , pp. 241-248
    • Krarup, T.1
  • 11
    • 0023873483 scopus 로고
    • Rapid Induction of ovarian granulosa cell tumors by 7,2-Dimethylbenz(a) anthracene in neonatally estrogenized mice
    • Taguchi O, Michael SD, Nishizuka Y. Rapid Induction of ovarian granulosa cell tumors by 7,2-Dimethylbenz(a)anthracene in neonatally estrogenized mice. Cancer Res 1988;48: 425-9.
    • (1988) Cancer Res , vol.48 , pp. 425-429
    • Taguchi, O.1    Michael, S.D.2    Nishizuka, Y.3
  • 12
    • 72949108008 scopus 로고    scopus 로고
    • Risk factors for epithelial ovarian cancer by histologic subtype
    • Gates MA, Rosner BA, Hecht JL, Tworoger SS. Risk factors for epithelial ovarian cancer by histologic subtype. Am J Epidemiol 2010;171: 45-53.
    • (2010) Am J Epidemiol , vol.171 , pp. 45-53
    • Gates, M.A.1    Rosner, B.A.2    Hecht, J.L.3    Tworoger, S.S.4
  • 13
    • 0038402728 scopus 로고    scopus 로고
    • Cigarette smoking and the risk of invasive epithelial ovarian cancer in a prospective cohort study
    • Terry PD, Miller AB, Jones JG, Rohan TE. Cigarette smoking and the risk of invasive epithelial ovarian cancer in a prospective cohort study. Eur J Cancer 2003;39: 1157-64.
    • (2003) Eur J Cancer , vol.39 , pp. 1157-1164
    • Terry, P.D.1    Miller, A.B.2    Jones, J.G.3    Rohan, T.E.4
  • 14
    • 0019476242 scopus 로고
    • Infertility in Mice exposed in utero to benzo(a)pyrene
    • MacKenzie KM, Angevine DM. Infertility in Mice exposed in utero to benzo(a)pyrene. Biol Reprod 1981;24: 183-91.
    • (1981) Biol Reprod , vol.24 , pp. 183-191
    • MacKenzie, K.M.1    Angevine, D.M.2
  • 15
    • 0019767216 scopus 로고
    • Diaplacental Initiation of NMRI Mice with 7,12-dimethylbenz[a]anthracene during gestation days 6-20 and postnatal treatment of the F1-generation with the phorbol ester 12-O-tetradecanoylphorbol-13-acetate: Tumor incidence in organs other than skin
    • Goerttler K, Loehrke H, Hesse B, Milz A, Schweizer J. Diaplacental Initiation of NMRI Mice with 7,12-dimethylbenz[a]anthracene during gestation days 6-20 and postnatal treatment of the F1-generation with the phorbol ester 12-O-tetradecanoylphorbol-13-acetate: tumor incidence in organs other than skin. Carcinogenesis 1981;2: 1087-94.
    • (1981) Carcinogenesis , vol.2 , pp. 1087-1094
    • Goerttler, K.1    Loehrke, H.2    Hesse, B.3    Milz, A.4    Schweizer, J.5
  • 16
    • 84856343660 scopus 로고    scopus 로고
    • Transplacental carcinogenesis with Dibenz[def,p]chrysene (DBC): Timing of maternal exposures determines target tissue response in offspring
    • Shorey LE, Castro DJ, Baird WM, Siddens LK, Löhr CV, Matzke MM, et al. Transplacental carcinogenesis with Dibenz[def,p]chrysene (DBC): timing of maternal exposures determines target tissue response in offspring. Cancer Lett 2012;317: 49-55.
    • (2012) Cancer Lett , vol.317 , pp. 49-55
    • Shorey, L.E.1    Castro, D.J.2    Baird, W.M.3    Siddens, L.K.4    Löhr, C.V.5    Matzke, M.M.6
  • 17
    • 20444412643 scopus 로고    scopus 로고
    • Metabolic activation of polycyclic aromatic hydrocarbon and heterocyclic aromatic hydrocarbons and DNA damage: A review
    • Xue W, Warshawsky D. Metabolic activation of polycyclic aromatic hydrocarbon and heterocyclic aromatic hydrocarbons and DNA damage: a review. Toxicol Appl Pharmacol 2005;206: 73-93.
    • (2005) Toxicol Appl Pharmacol , vol.206 , pp. 73-93
    • Xue, W.1    Warshawsky, D.2
  • 18
    • 0038706167 scopus 로고    scopus 로고
    • Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues
    • Choudhary D, Jansson I, Schenkman JB, Sarfarazi M, Stoilov I. Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues. Arch Biochem Biophys 2003;414: 91-100.
    • (2003) Arch Biochem Biophys , vol.414 , pp. 91-100
    • Choudhary, D.1    Jansson, I.2    Schenkman, J.B.3    Sarfarazi, M.4    Stoilov, I.5
  • 19
    • 14744302949 scopus 로고    scopus 로고
    • Expression pattern of mouse and human CYP orthologs (Families 1-4) during development and in different adult tissues
    • Choudhary D, Jansson I, Stoilov I, Sarfarazi M, Schenkman JB. Expression pattern of mouse and human CYP orthologs (Families 1-4) during development and in different adult tissues. Arch Biochem Biophys 2005;436: 50-61.
    • (2005) Arch Biochem Biophys , vol.436 , pp. 50-61
    • Choudhary, D.1    Jansson, I.2    Stoilov, I.3    Sarfarazi, M.4    Schenkman, J.B.5
  • 20
    • 0030776172 scopus 로고    scopus 로고
    • Expression and Inducibility of P450 Enzymes during Liver Ontogeny
    • Rich KJ, Boobis AR. Expression and Inducibility of P450 Enzymes during Liver Ontogeny. Microsc Res Tech 1997;39: 424-35.
    • (1997) Microsc Res Tech , vol.39 , pp. 424-435
    • Rich, K.J.1    Boobis, A.R.2
  • 21
    • 61349091797 scopus 로고    scopus 로고
    • Oxidative stress in developmental origins of disease: Teratogenesis, neurodevelopmental deficits, and cancer
    • Wells PG, McCallum GP, Chen CS, Henderson JT, Lee CJJ, Perstin J, et al. Oxidative stress in developmental origins of disease: teratogenesis, neurodevelopmental deficits, and cancer. Toxicol Sci 2009;108: 4-18.
    • (2009) Toxicol Sci , vol.108 , pp. 4-18
    • Wells, P.G.1    McCallum, G.P.2    Chen, C.S.3    Henderson, J.T.4    Lee, C.J.J.5    Perstin, J.6
  • 22
    • 0029956983 scopus 로고    scopus 로고
    • Glutathione-Stransferase A1-1-catalysed conjugation of bay and fjord region diol epoxides of polycyclic aromatic hydrocarbons with glutathione
    • Jernström B, Funk M, Frank H, Mannervik B, Seidel A. Glutathione-Stransferase A1-1-catalysed conjugation of bay and fjord region diol epoxides of polycyclic aromatic hydrocarbons with glutathione. Carcinogenesis 1996;17: 1491-8.
    • (1996) Carcinogenesis , vol.17 , pp. 1491-1498
    • Jernström, B.1    Funk, M.2    Frank, H.3    Mannervik, B.4    Seidel, A.5
  • 23
    • 0024458426 scopus 로고
    • Effects of glutathione transferase activity on benzo[a]pyrene 7,8-dihydrodiol metabolism and mutagenesis studied in a mammalian cell co-cultivation assay
    • Romert L, Dock L, Jenssen D, Jernström B. Effects of glutathione transferase activity on benzo[a]pyrene 7,8-dihydrodiol metabolism and mutagenesis studied in a mammalian cell co-cultivation assay. Cancer Res 1989;10: 1701-7.
    • (1989) Cancer Res , vol.10 , pp. 1701-1707
    • Romert, L.1    Dock, L.2    Jenssen, D.3    Jernström, B.4
  • 24
    • 0034667408 scopus 로고    scopus 로고
    • Regulation of g-glutamate cysteine ligase expression by oxidative stress in the mouse preimplantation embryo
    • Stover SK, Gushansky GA, Salmen JJ, Gardiner CS. Regulation of g-glutamate cysteine ligase expression by oxidative stress in the mouse preimplantation embryo. Toxicol Appl Pharmacol 2000;168: 153-9.
    • (2000) Toxicol Appl Pharmacol , vol.168 , pp. 153-159
    • Stover, S.K.1    Gushansky, G.A.2    Salmen, J.J.3    Gardiner, C.S.4
  • 26
    • 65049090510 scopus 로고    scopus 로고
    • Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase
    • Franklin CC, Backos DS, Mohar I, White CC, Forman HJ, Kavanagh TJ. Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase. Mol Aspects Med 2009;30: 86-98.
    • (2009) Mol Aspects Med , vol.30 , pp. 86-98
    • Franklin, C.C.1    Backos, D.S.2    Mohar, I.3    White, C.C.4    Forman, H.J.5    Kavanagh, T.J.6
  • 27
    • 0034694871 scopus 로고    scopus 로고
    • Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: Embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous
    • Dalton TP, Dieter MZ, Yang Y, Shertzer HG, Nebert DW. Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous. Biochem Biophys Res Commun 2000;279: 324-9.
    • (2000) Biochem Biophys Res Commun , vol.279 , pp. 324-329
    • Dalton, T.P.1    Dieter, M.Z.2    Yang, Y.3    Shertzer, H.G.4    Nebert, D.W.5
  • 29
    • 0037147240 scopus 로고    scopus 로고
    • Initial characterization of the glutamate cysteine ligase modifier subunit Gclm (-/-) knockout mouse: Novel model system for severely compromised oxidative stress response
    • Yang Y, Dieter MZ, Chen Y, Shertzer HG, Nebert DW, Dalton TP. Initial characterization of the glutamate cysteine ligase modifier subunit Gclm (-/-) knockout mouse: novel model system for severely compromised oxidative stress response. J Biol Chem 2002;277: 49446-52.
    • (2002) J Biol Chem , vol.277 , pp. 49446-49452
    • Yang, Y.1    Dieter, M.Z.2    Chen, Y.3    Shertzer, H.G.4    Nebert, D.W.5    Dalton, T.P.6
  • 30
    • 38449087850 scopus 로고    scopus 로고
    • Glutamate cysteine ligase modifier subunit deficiency and gender as determinants of acetaminophen-induced hepatotoxicity in mice
    • McConnachie LA, Mohar I, Hudson FN, Ware CB, Ladiges WC, Fernandez C, et al. Glutamate cysteine ligase modifier subunit deficiency and gender as determinants of acetaminophen-induced hepatotoxicity in mice. Toxicol Sci 2007;99: 628-36.
    • (2007) Toxicol Sci , vol.99 , pp. 628-636
    • McConnachie, L.A.1    Mohar, I.2    Hudson, F.N.3    Ware, C.B.4    Ladiges, W.C.5    Fernandez, C.6
  • 31
    • 79959435826 scopus 로고    scopus 로고
    • Lack of maternal glutamate cysteine ligase modifier subunit (Gclm) decreases oocyte glutathione concentrations and disrupts preimplantation development in mice
    • Nakamura BN, Fielder TJ, Hoang YD, Lim J, McConnachie LA, Kavanagh TJ, et al. Lack of maternal glutamate cysteine ligase modifier subunit (Gclm) decreases oocyte glutathione concentrations and disrupts preimplantation development in mice. Endocrinology 2011;152: 2806-15.
    • (2011) Endocrinology , vol.152 , pp. 2806-2815
    • Nakamura, B.N.1    Fielder, T.J.2    Hoang, Y.D.3    Lim, J.4    McConnachie, L.A.5    Kavanagh, T.J.6
  • 32
    • 33751072387 scopus 로고    scopus 로고
    • Neurotoxicity of domoic acid in cerebellar granule neurons in a genetic model of glutathione deficiency
    • Giordano G, White CC, McConnachie LA, Fernandez C, Kavanagh TJ, Costa LG. Neurotoxicity of domoic acid in cerebellar granule neurons in a genetic model of glutathione deficiency. Mol Pharmacol 2006;70: 2116-26.
    • (2006) Mol Pharmacol , vol.70 , pp. 2116-2126
    • Giordano, G.1    White, C.C.2    McConnachie, L.A.3    Fernandez, C.4    Kavanagh, T.J.5    Costa, L.G.6
  • 33
    • 0023892774 scopus 로고
    • Size-frequency analysis of atresia in cycling rats
    • Hirshfield AN. Size-frequency analysis of atresia in cycling rats. Biol Reprod 1988;38: 1181-8.
    • (1988) Biol Reprod , vol.38 , pp. 1181-1188
    • Hirshfield, A.N.1
  • 34
    • 33645119762 scopus 로고    scopus 로고
    • Characterizing the ovotoxicity of cyclophosphamide metabolites on cultured mouse ovaries
    • Desmeules P, Devine PJ. Characterizing the ovotoxicity of cyclophosphamide metabolites on cultured mouse ovaries. Toxicol Sci 2006;90: 500-9.
    • (2006) Toxicol Sci , vol.90 , pp. 500-509
    • Desmeules, P.1    Devine, P.J.2
  • 35
    • 0037225599 scopus 로고    scopus 로고
    • Evidence for genetic modifiers of ovarian follicular endowment and development from studies of five inbred mouse strains
    • Canning J, Takai Y, Tilly JL. Evidence for genetic modifiers of ovarian follicular endowment and development from studies of five inbred mouse strains. Endocrinology 2002;144: 9-12.
    • (2002) Endocrinology , vol.144 , pp. 9-12
    • Canning, J.1    Takai, Y.2    Tilly, J.L.3
  • 36
    • 34247874637 scopus 로고    scopus 로고
    • A reduction of cyclooxygenase 2 gene dosage counters the ovarian morphological aging and tumor phenotype in Wv mice
    • Yang W-L, Cai KQ, Smedberg JL, Smith ER, Klein-Szanto A, Hamilton TC, et al. A reduction of cyclooxygenase 2 gene dosage counters the ovarian morphological aging and tumor phenotype in Wv mice. Am J Pathol 2007;170: 1325-36.
    • (2007) Am J Pathol , vol.170 , pp. 1325-1336
    • Yang, W.-L.1    Cai, K.Q.2    Smedberg, J.L.3    Smith, E.R.4    Klein-Szanto, A.5    Hamilton, T.C.6
  • 37
    • 77955657972 scopus 로고    scopus 로고
    • An ethnic-specific polymorphism in the catalytic subunit of glutamatecysteine ligase impairs the production of glutathione intermediates in vitro
    • Le TM, Willis AS, Barr FE, Cunningham GR, Canter JA, Owens SE, et al. An ethnic-specific polymorphism in the catalytic subunit of glutamatecysteine ligase impairs the production of glutathione intermediates in vitro. Mol Genet Metab 2010;101: 55-61.
    • (2010) Mol Genet Metab , vol.101 , pp. 55-61
    • Le, T.M.1    Willis, A.S.2    Barr, F.E.3    Cunningham, G.R.4    Canter, J.A.5    Owens, S.E.6
  • 38
    • 0037172653 scopus 로고    scopus 로고
    • Polymorphism in the 50-flanking region of the human glutamate-cysteine ligase modifier subunit gene is associated with myocardial infarction
    • Nakamura S-I, Kugiyama K, Sugiyama S, Miyamoto S, Koide S-I, Fukushima H, et al. Polymorphism in the 50-flanking region of the human glutamate-cysteine ligase modifier subunit gene is associated with myocardial infarction. Circulation 2002;105: 2968-73.
    • (2002) Circulation , vol.105 , pp. 2968-2973
    • Nakamura, S.-I.1    Kugiyama, K.2    Sugiyama, S.3    Miyamoto, S.4    Koide, S.-I.5    Fukushima, H.6
  • 39
    • 48449091602 scopus 로고    scopus 로고
    • Functional significance of the CAG trinucleotide-repeat polymorphism in the gene for the catalytic subunit of g-glutamylcysteine ligase
    • Nichenametla SN, Ellison I, Calcagnotto A, Lazarus P, Muscat JE, Richie JPJ. Functional significance of the CAG trinucleotide-repeat polymorphism in the gene for the catalytic subunit of g-glutamylcysteine ligase. Free Radic Biol Med 2008;45: 645-50.
    • (2008) Free Radic Biol Med , vol.45 , pp. 645-650
    • Nichenametla, S.N.1    Ellison, I.2    Calcagnotto, A.3    Lazarus, P.4    Muscat, J.E.5    Richie, J.P.J.6
  • 40
    • 0034980722 scopus 로고    scopus 로고
    • Evidence for functionally significant polymorphism of human glutamate cysteine ligase catalytic subunit: Association with glutathione levels and drug resistance in the National Cancer Institute tumor cell line panel
    • Walsh AC, Feulner JA, Reilly A. Evidence for functionally significant polymorphism of human glutamate cysteine ligase catalytic subunit: association with glutathione levels and drug resistance in the National Cancer Institute tumor cell line panel. Toxicol Sci 2001;61: 218-23.
    • (2001) Toxicol Sci , vol.61 , pp. 218-223
    • Walsh, A.C.1    Feulner, J.A.2    Reilly, A.3
  • 41
    • 0021136354 scopus 로고
    • Murine strain differences in ovotoxicity following intraovarian injection with benzo(a)pyrene, (+)-(7R,8S)-oxide, (-)-(7R,8S)-dihydrodiol, or (+)-(7R,8S)-diol- (9S,10R)-epoxide-2
    • Takizawa K, Yagi H, Jerina DM, Mattison DR. Murine strain differences in ovotoxicity following intraovarian injection with benzo(a)pyrene, (+)-(7R,8S)-oxide, (-)-(7R,8S)-dihydrodiol, or (+)-(7R,8S)-diol- (9S,10R)-epoxide-2. Cancer Res 1984;44: 2571-6.
    • (1984) Cancer Res , vol.44 , pp. 2571-2576
    • Takizawa, K.1    Yagi, H.2    Jerina, D.M.3    Mattison, D.R.4
  • 42
    • 33645105462 scopus 로고    scopus 로고
    • Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1metabolism required for immunedamage independent of total-body burden and clearance rate
    • Uno S, Dalton TP, Dragin N, Curran CP, Derkenne S, Miller ML, et al. Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1metabolism required for immunedamage independent of total-body burden and clearance rate. Mol Pharmacol 2006;69: 1103-14.
    • (2006) Mol Pharmacol , vol.69 , pp. 1103-1114
    • Uno, S.1    Dalton, T.P.2    Dragin, N.3    Curran, C.P.4    Derkenne, S.5    Miller, M.L.6
  • 43
    • 0344559071 scopus 로고
    • Cell-specific induction of mouse cyp1a1 RNA during development
    • Dey A, Westphal H, Nebert DW. Cell-specific induction of mouse cyp1a1 RNA during development. Proc Natl Acad Sci U S A 1989;86: 7446-50.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 7446-7450
    • Dey, A.1    Westphal, H.2    Nebert, D.W.3
  • 44
    • 0031036750 scopus 로고    scopus 로고
    • Evidence for embryonic prostaglandin H synthase catalyzed bioactivation and reactive oxygen species-mediated oxidation of cellular macromolecules in pheytoin and benzo[a]pyrene teratogenesis
    • Winn LM, Wells PG. Evidence for embryonic prostaglandin H synthase catalyzed bioactivation and reactive oxygen species-mediated oxidation of cellular macromolecules in pheytoin and benzo[a]pyrene teratogenesis. Free Radic Biol Med 1997;22: 607-21.
    • (1997) Free Radic Biol Med , vol.22 , pp. 607-621
    • Winn, L.M.1    Wells, P.G.2
  • 45
    • 0036310321 scopus 로고    scopus 로고
    • Embryonic prostaglandin H synthase-2 (PHS-2) expression and benzo[a]pyrene teratogenicity in PHS-2 knockout mice
    • Parman T, Wells PG. Embryonic prostaglandin H synthase-2 (PHS-2) expression and benzo[a]pyrene teratogenicity in PHS-2 knockout mice. FASEB J 2002;16: 1001-9.
    • (2002) FASEB J , vol.16 , pp. 1001-1009
    • Parman, T.1    Wells, P.G.2
  • 46
    • 84857929938 scopus 로고    scopus 로고
    • Increased sensitivity to testicular toxicity of transplacental benzo[ a]pyrene exposure in male glutamate cysteine ligase modifier subunit Gclm-/-) knockout mice
    • Nakamura BN, Mohar I, Lawson GW, Hoang YD, Cortes MM, Ortiz L, et al. Increased sensitivity to testicular toxicity of transplacental benzo[ a]pyrene exposure in male glutamate cysteine ligase modifier subunit Gclm-/-) knockout mice. Toxicol Sci 2012;126: 227-41.
    • (2012) Toxicol Sci , vol.126 , pp. 227-241
    • Nakamura, B.N.1    Mohar, I.2    Lawson, G.W.3    Hoang, Y.D.4    Cortes, M.M.5    Ortiz, L.6
  • 48
    • 0037328718 scopus 로고    scopus 로고
    • CYP1B1 determines susceptibility to low doses of 7,12- dimethylbenz[a]anthracene-induced ovarian cancers in mice: Correlation of CYP1B1-mediated DNA adducts with carcinogenicity
    • Buters J, Quintanilla-Martinez L, Schober W, Soballa VJ, Hintermair J, Wolff T, et al. CYP1B1 determines susceptibility to low doses of 7,12- dimethylbenz[a]anthracene-induced ovarian cancers in mice: correlation of CYP1B1-mediated DNA adducts with carcinogenicity. Carcinogenesis 2003;24: 327-34.
    • (2003) Carcinogenesis , vol.24 , pp. 327-334
    • Buters, J.1    Quintanilla-Martinez, L.2    Schober, W.3    Soballa, V.J.4    Hintermair, J.5    Wolff, T.6
  • 49
    • 77958559605 scopus 로고    scopus 로고
    • Ovarian susceptibility to benzo[ a]pyrene: Tissue burden of metabolites and DNA adducts in F-344 rats
    • Ramesh A, Archibong AE, Niaz MS. Ovarian susceptibility to benzo[ a]pyrene: tissue burden of metabolites and DNA adducts in F-344 rats. J Toxicol Environ Health, Part A 2010;73: 1611-25.
    • (2010) J Toxicol Environ Health, Part A , vol.73 , pp. 1611-1625
    • Ramesh, A.1    Archibong, A.E.2    Niaz, M.S.3
  • 50
    • 0034928843 scopus 로고    scopus 로고
    • Aromatic hydrocarbon receptor-driven bax gene expression is required for premature ovarian failure caused by biohazardous environmental chemicals
    • Matikainen T, Perez GI, Jurisicova A, Pru JK, Schlezinger JJ, Ryu H-Y, et al. Aromatic hydrocarbon receptor-driven bax gene expression is required for premature ovarian failure caused by biohazardous environmental chemicals. Nat Genet 2001;28: 355-60.
    • (2001) Nat Genet , vol.28 , pp. 355-360
    • Matikainen, T.1    Perez, G.I.2    Jurisicova, A.3    Pru, J.K.4    Schlezinger, J.J.5    Ryu, H.-Y.6


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