Isolation housing exacerbates Alzheimer's disease-like pathophysiology in aged APP/PS1 mice

International Journal of Neuropsychopharmacology

Volumn 18, Issue 7, 2015, Pages 1-10

  Huang, Huang ^a   Wang, Linmei ^a   Cao, Min ^a   Marshall, Charles ^b   Gao, Junying ^a   Xiao, Na ^a   Hu, Gang ^a   Xiao, Ming ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; GAMMA SECRETASE; MEMBRANE METALLOENDOPEPTIDASE; MYELIN ASSOCIATED GLYCOPROTEIN; AMYLOID PRECURSOR PROTEIN; APP PROTEIN, HUMAN; SECRETASE;

AGED; ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL HOUSING; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMICAL ANALYSIS; BRAIN ATROPHY; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE EXACERBATION; GLIA CELL; HIPPOCAMPUS; MALE; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; SOCIAL ISOLATION; SOCIAL LIFE; SYNAPSE; TRANSGENIC MOUSE; AGING; ANIMAL; ATROPHY; COGNITION; DISEASE MODEL; GENETICS; GLIA; INFLAMMATION; LOCOMOTION; MAZE TEST; METABOLISM; MOTOR ACTIVITY; MYELIN SHEATH; PATHOLOGY; PATHOPHYSIOLOGY; PSYCHOLOGY;

AGING; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ATROPHY; BEHAVIOR, ANIMAL; COGNITION; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; INFLAMMATION; LOCOMOTION; MALE; MAZE LEARNING; MICE; MICE, TRANSGENIC; MOTOR ACTIVITY; MYELIN SHEATH; NEPRILYSIN; NEUROGLIA; PLAQUE, AMYLOID; SOCIAL ISOLATION; SYNAPSES;

EID: 84939159037     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1093/ijnp/pyu116     Document Type: Article

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