메뉴 건너뛰기




Volumn 22, Issue 9, 2015, Pages 1489-1501

CFLIP is critical for oligodendrocyte protection from inflammation

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; FLICE INHIBITORY PROTEIN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; MYELIN; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; SHORT HAIRPIN RNA; TUMOR NECROSIS FACTOR ALPHA; CASPASE;

EID: 84938969160     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2014.237     Document Type: Article
Times cited : (12)

References (65)
  • 1
    • 0029882579 scopus 로고    scopus 로고
    • Reversible inhibitory effects of interferon-gamma and tumour necrosis factor-alpha on oligodendroglial lineage cell proliferation and differentiation in vitro
    • Agresti C, D'Urso D, Levi G. Reversible inhibitory effects of interferon-gamma and tumour necrosis factor-alpha on oligodendroglial lineage cell proliferation and differentiation in vitro. Eur J Neurosci 1996; 8: 1106-1116.
    • (1996) Eur J Neurosci , vol.8 , pp. 1106-1116
    • Agresti, C.1    D'Urso, D.2    Levi, G.3
  • 2
    • 79955753777 scopus 로고    scopus 로고
    • Oligodendrocyte progenitors reversibly exit the cell cycle and give rise to astrocytes in response to interferon-gamma
    • Tanner DC, Cherry JD, Mayer-Proschel M. Oligodendrocyte progenitors reversibly exit the cell cycle and give rise to astrocytes in response to interferon-gamma. J Neurosci 2011; 31: 6235-6246.
    • (2011) J Neurosci , vol.31 , pp. 6235-6246
    • Tanner, D.C.1    Cherry, J.D.2    Mayer-Proschel, M.3
  • 3
    • 0032217056 scopus 로고    scopus 로고
    • TNFalpha potentiates IFNgamma-induced cell death in oligodendrocyte progenitors
    • Andrews T, Zhang P, Bhat NR. TNFalpha potentiates IFNgamma-induced cell death in oligodendrocyte progenitors. J Neurosci Res 1998; 54: 574-583.
    • (1998) J Neurosci Res , vol.54 , pp. 574-583
    • Andrews, T.1    Zhang, P.2    Bhat, N.R.3
  • 4
    • 0032522813 scopus 로고    scopus 로고
    • Developing and mature oligodendrocytes respond differently to the immune cytokine interferon-gamma
    • Baerwald KD, Popko B. Developing and mature oligodendrocytes respond differently to the immune cytokine interferon-gamma. J Neurosci Res 1998; 52: 230-239.
    • (1998) J Neurosci Res , vol.52 , pp. 230-239
    • Baerwald, K.D.1    Popko, B.2
  • 5
    • 22344435167 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-gamma
    • Lin W, Harding HP, Ron D, Popko B. Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-gamma. J Cell Biol 2005; 169: 603-612.
    • (2005) J Cell Biol , vol.169 , pp. 603-612
    • Lin, W.1    Harding, H.P.2    Ron, D.3    Popko, B.4
  • 6
    • 27844562681 scopus 로고    scopus 로고
    • Interferon-gamma inhibits cell cycle exit in differentiating oligodendrocyte progenitor cells
    • Chew LJ, King WC, Kennedy A, Gallo V. Interferon-gamma inhibits cell cycle exit in differentiating oligodendrocyte progenitor cells. Glia 2005; 52: 127-143.
    • (2005) Glia , vol.52 , pp. 127-143
    • Chew, L.J.1    King, W.C.2    Kennedy, A.3    Gallo, V.4
  • 7
    • 0029410743 scopus 로고
    • Interferon-gamma-induced oligodendrocyte cell death: Implications for the pathogenesis of multiple sclerosis
    • Vartanian T, Li Y, Zhao M, Stefansson K. Interferon-gamma-induced oligodendrocyte cell death: implications for the pathogenesis of multiple sclerosis. Mol Med 1995; 1: 732-743.
    • (1995) Mol Med , vol.1 , pp. 732-743
    • Vartanian, T.1    Li, Y.2    Zhao, M.3    Stefansson, K.4
  • 8
    • 33846806080 scopus 로고    scopus 로고
    • A little stress is good: IFN-gamma, demyelination, and multiple sclerosis
    • Lees JR, Cross AH. A little stress is good: IFN-gamma, demyelination, and multiple sclerosis. J Clin Invest 2007; 117: 297-299.
    • (2007) J Clin Invest , vol.117 , pp. 297-299
    • Lees, J.R.1    Cross, A.H.2
  • 9
    • 33846811702 scopus 로고    scopus 로고
    • The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage
    • Lin W, Bailey SL, Ho H, Harding HP, Ron D, Miller SD et al. The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage. J Clin Invest 2007; 117: 448-456.
    • (2007) J Clin Invest , vol.117 , pp. 448-456
    • Lin, W.1    Bailey, S.L.2    Ho, H.3    Harding, H.P.4    Ron, D.5    Miller, S.D.6
  • 10
    • 0031659763 scopus 로고    scopus 로고
    • Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: Models for multiple sclerosis with primary oligodendrogliopathy
    • Akassoglou K, Bauer J, Kassiotis G, Pasparakis M, Lassmann H, Kollias G et al. Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy. Am J Pathol 1998; 153: 801-813.
    • (1998) Am J Pathol , vol.153 , pp. 801-813
    • Akassoglou, K.1    Bauer, J.2    Kassiotis, G.3    Pasparakis, M.4    Lassmann, H.5    Kollias, G.6
  • 11
    • 27644510002 scopus 로고    scopus 로고
    • Tumour necrosis factor-induced death of adult human oligodendrocytes is mediated by apoptosis inducing factor
    • Jurewicz A, Matysiak M, Tybor K, Kilianek L, Raine CS, Selmaj K. Tumour necrosis factor-induced death of adult human oligodendrocytes is mediated by apoptosis inducing factor. Brain 2005; 128: 2675-2688.
    • (2005) Brain , vol.128 , pp. 2675-2688
    • Jurewicz, A.1    Matysiak, M.2    Tybor, K.3    Kilianek, L.4    Raine, C.S.5    Selmaj, K.6
  • 12
    • 0028169881 scopus 로고
    • N-acetyl-L-cysteine is a pluripotent protector against cell death and enhancer of trophic factor-mediated cell survival in vitro
    • Mayer M, Noble M. N-acetyl-L-cysteine is a pluripotent protector against cell death and enhancer of trophic factor-mediated cell survival in vitro. Proc Natl Acad Sci USA 1994; 91: 7496-7500.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7496-7500
    • Mayer, M.1    Noble, M.2
  • 13
    • 0030221758 scopus 로고    scopus 로고
    • Cytokines in inflammatory brain lesions: Helpful and harmful
    • Merrill JE, Benveniste EN. Cytokines in inflammatory brain lesions: helpful and harmful. Trends Neurosci 1996; 19: 331-338.
    • (1996) Trends Neurosci , vol.19 , pp. 331-338
    • Merrill, J.E.1    Benveniste, E.N.2
  • 14
    • 0028855346 scopus 로고
    • Prevention of chronic relapsing experimental autoimmune encephalomyelitis by soluble tumor necrosis factor receptor i
    • Selmaj K, Papierz W, Glabinski A, Kohno T. Prevention of chronic relapsing experimental autoimmune encephalomyelitis by soluble tumor necrosis factor receptor I. J Neuroimmunol 1995; 56: 135-141.
    • (1995) J Neuroimmunol , vol.56 , pp. 135-141
    • Selmaj, K.1    Papierz, W.2    Glabinski, A.3    Kohno, T.4
  • 15
    • 0034069944 scopus 로고    scopus 로고
    • Interferon-gamma modulates human oligodendrocyte susceptibility to Fas-mediated apoptosis
    • Pouly S, Becher B, Blain M, Antel JP. Interferon-gamma modulates human oligodendrocyte susceptibility to Fas-mediated apoptosis. J Neuropathol Exp Neurol 2000; 59: 280-286.
    • (2000) J Neuropathol Exp Neurol , vol.59 , pp. 280-286
    • Pouly, S.1    Becher, B.2    Blain, M.3    Antel, J.P.4
  • 16
    • 2642537740 scopus 로고    scopus 로고
    • Cytokine-induced cell death in human oligodendroglial cell lines. II: Alterations in gene expression induced by interferon-gamma and tumor necrosis factor-alpha
    • Buntinx M, Gielen E, Van Hummelen P, Raus J, Ameloot M, Steels P et al. Cytokine-induced cell death in human oligodendroglial cell lines. II: Alterations in gene expression induced by interferon-gamma and tumor necrosis factor-alpha. J Neurosci Res 2004; 76: 846-861.
    • (2004) J Neurosci Res , vol.76 , pp. 846-861
    • Buntinx, M.1    Gielen, E.2    Van Hummelen, P.3    Raus, J.4    Ameloot, M.5    Steels, P.6
  • 17
    • 0033558337 scopus 로고    scopus 로고
    • Differential responses of oligodendrocytes to tumor necrosis factor and other pro-apoptotic agents: Role of ceramide in apoptosis
    • Scurlock B, Dawson G. Differential responses of oligodendrocytes to tumor necrosis factor and other pro-apoptotic agents: role of ceramide in apoptosis. J Neurosci Res 1999; 55: 514-522.
    • (1999) J Neurosci Res , vol.55 , pp. 514-522
    • Scurlock, B.1    Dawson, G.2
  • 18
    • 1842589255 scopus 로고    scopus 로고
    • Caspase-1 mediates Fas-induced apoptosis and is up-regulated by interferon-gamma in human astrocytoma cells
    • Choi C, Jeong E, Benveniste EN. Caspase-1 mediates Fas-induced apoptosis and is up-regulated by interferon-gamma in human astrocytoma cells. J Neurooncol 2004; 67: 167-176.
    • (2004) J Neurooncol , vol.67 , pp. 167-176
    • Choi, C.1    Jeong, E.2    Benveniste, E.N.3
  • 19
    • 0022633381 scopus 로고
    • Recombinant tumor necrosis factor: Its effect and its synergism with interferon-? on a variety of normal and transformed human cell lines
    • Fransen L, Van der Heyden J, Ruysschaert R, Fiers W. Recombinant tumor necrosis factor: its effect and its synergism with interferon-? on a variety of normal and transformed human cell lines.. Eur J Cancer Clin Oncol 1986; 22: 419-426.
    • (1986) Eur J Cancer Clin Oncol , vol.22 , pp. 419-426
    • Fransen, L.1    Van Der Heyden, J.2    Ruysschaert, R.3    Fiers, W.4
  • 20
    • 33847223756 scopus 로고    scopus 로고
    • Interferon-oligodendrocyte interactions in the regulation of experimental autoimmune encephalomyelitis
    • Balabanov R, Strand K, Goswami R, McMahon E, Begolka W, Miller SD et al. Interferon-oligodendrocyte interactions in the regulation of experimental autoimmune encephalomyelitis. J Neurosci 2007; 27: 2013-2024.
    • (2007) J Neurosci , vol.27 , pp. 2013-2024
    • Balabanov, R.1    Strand, K.2    Goswami, R.3    McMahon, E.4    Begolka, W.5    Miller, S.D.6
  • 21
    • 84860523529 scopus 로고    scopus 로고
    • Interferon-gamma activates nuclear factor-kappa B in oligodendrocytes through a process mediated by the unfolded protein response
    • Lin Y, Jamison S, Lin W. Interferon-gamma activates nuclear factor-kappa B in oligodendrocytes through a process mediated by the unfolded protein response. PLoS One 2012; 7: e36408.
    • (2012) PLoS One , vol.7 , pp. e36408
    • Lin, Y.1    Jamison, S.2    Lin, W.3
  • 22
    • 0030704327 scopus 로고    scopus 로고
    • Effects of thyroid hormone on embryonic oligodendrocyte precursor cell development in vivo and in vitro
    • Ahlgren SC, Wallace H, Bishop J, Neophytou C, Raff MC. Effects of thyroid hormone on embryonic oligodendrocyte precursor cell development in vivo and in vitro. Mol Cell Neurosci 1997; 9: 420-432.
    • (1997) Mol Cell Neurosci , vol.9 , pp. 420-432
    • Ahlgren, S.C.1    Wallace, H.2    Bishop, J.3    Neophytou, C.4    Raff, M.C.5
  • 23
    • 0031026190 scopus 로고    scopus 로고
    • Accumulation of the cyclin-dependent kinase inhibitor p27/Kip1 and the timing of oligodendrocyte differentiation
    • Durand B, Gao FB, Raff M. Accumulation of the cyclin-dependent kinase inhibitor p27/Kip1 and the timing of oligodendrocyte differentiation. EMBO J 1997; 16: 306-317.
    • (1997) EMBO J , vol.16 , pp. 306-317
    • Durand, B.1    Gao, F.B.2    Raff, M.3
  • 24
    • 0027524531 scopus 로고
    • Glial cell mitogens bFGF and PDGF differentially regulate development of O4+GalC-oligodendrocyte progenitors
    • Gard AL, Pfeiffer SE. Glial cell mitogens bFGF and PDGF differentially regulate development of O4+GalC-oligodendrocyte progenitors. Dev Biol 1993; 159: 618-630.
    • (1993) Dev Biol , vol.159 , pp. 618-630
    • Gard, A.L.1    Pfeiffer, S.E.2
  • 25
    • 0026612170 scopus 로고
    • Stage specific, (O4+GalC-) isolated oligodendrocyte progenitors produce MBP+ myelin in vivo
    • Warrington AE, Barbarese E, Pfeiffer SE. Stage specific, (O4+GalC-) isolated oligodendrocyte progenitors produce MBP+ myelin in vivo. Dev Neurosci 1992; 14: 93-97.
    • (1992) Dev Neurosci , vol.14 , pp. 93-97
    • Warrington, A.E.1    Barbarese, E.2    Pfeiffer, S.E.3
  • 26
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell JE Jr., Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994; 264: 1415-1421.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell, J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 28
    • 0242662865 scopus 로고    scopus 로고
    • STAT-1 alpha and IFN-gamma as modulators of TNF-alpha signaling in macrophages: Regulation and functional implications of the TNF receptor 1: STAT-1 alpha complex
    • Wesemann DR, Benveniste EN. STAT-1 alpha and IFN-gamma as modulators of TNF-alpha signaling in macrophages: regulation and functional implications of the TNF receptor 1: STAT-1 alpha complex. J Immunol 2003; 171: 5313-5319.
    • (2003) J Immunol , vol.171 , pp. 5313-5319
    • Wesemann, D.R.1    Benveniste, E.N.2
  • 29
    • 9944229967 scopus 로고    scopus 로고
    • Biochemical mechanisms for translational regulation in synaptic plasticity
    • Klann E, Dever TE. Biochemical mechanisms for translational regulation in synaptic plasticity. Nat Rev Neurosci 2004; 5: 931-942.
    • (2004) Nat Rev Neurosci , vol.5 , pp. 931-942
    • Klann, E.1    Dever, T.E.2
  • 31
    • 33845627785 scopus 로고    scopus 로고
    • Impact of protein kinase PKR in cell biology: From antiviral to antiproliferative action
    • Garcia MA, Gil J, Ventoso I, Guerra S, Domingo E, Rivas C et al. Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action. Microbiol Mol Biol Rev 2006; 70: 1032-1060.
    • (2006) Microbiol Mol Biol Rev , vol.70 , pp. 1032-1060
    • Garcia, M.A.1    Gil, J.2    Ventoso, I.3    Guerra, S.4    Domingo, E.5    Rivas, C.6
  • 32
    • 55349142516 scopus 로고    scopus 로고
    • Enhanced integrated stress response promotes myelinating oligodendrocyte survival in response to interferon
    • Lin W, Kunkler PE, Harding HP, Ron D, Kraig RP, Popko B. Enhanced integrated stress response promotes myelinating oligodendrocyte survival in response to interferon-. Am J Pathol 2008; 173: 1508-1517.
    • (2008) Am J Pathol , vol.173 , pp. 1508-1517
    • Lin, W.1    Kunkler, P.E.2    Harding, H.P.3    Ron, D.4    Kraig, R.P.5    Popko, B.6
  • 33
    • 63649109017 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress in disorders of myelinating cells
    • Lin W, Popko B. Endoplasmic reticulum stress in disorders of myelinating cells. Nat Neurosci 2009; 12: 379-385.
    • (2009) Nat Neurosci , vol.12 , pp. 379-385
    • Lin, W.1    Popko, B.2
  • 34
    • 0028332026 scopus 로고
    • Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating i kappa B
    • Kumar A, Haque J, Lacoste J, Hiscott J, Williams BR. Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B. Proc Natl Acad Sci USA 1994; 91: 6288-6292.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 6288-6292
    • Kumar, A.1    Haque, J.2    Lacoste, J.3    Hiscott, J.4    Williams, B.R.5
  • 35
    • 17444449609 scopus 로고    scopus 로고
    • Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: Role of IRF-1 and NF-kappaB
    • Kumar A, Yang YL, Flati V, Der S, Kadereit S, Deb A et al. Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB. EMBO J 1997; 16: 406-416.
    • (1997) EMBO J , vol.16 , pp. 406-416
    • Kumar, A.1    Yang, Y.L.2    Flati, V.3    Der Kadereit S, S.4    Deb, A.5
  • 36
    • 0034746288 scopus 로고    scopus 로고
    • NF-?B in neuronal plasticity and neurodegenerative disorders
    • Mattson MP, Camandola S. NF-?B in neuronal plasticity and neurodegenerative disorders. J Clin Invest 2001; 107: 247-254.
    • (2001) J Clin Invest , vol.107 , pp. 247-254
    • Mattson, M.P.1    Camandola, S.2
  • 37
    • 0031172065 scopus 로고    scopus 로고
    • NF-kappa B. a crucial transcription factor for glial and neuronal cell function
    • O'Neill LA, Kaltschmidt C, NF-kappa B. a crucial transcription factor for glial and neuronal cell function. Trends Neurosci 1997; 20: 252-258.
    • (1997) Trends Neurosci , vol.20 , pp. 252-258
    • O'Neill, L.A.1    Kaltschmidt, C.2
  • 38
    • 84901669448 scopus 로고    scopus 로고
    • NF-?B signaling regulates myelination in the CNS
    • Blank T, Prinz M. NF-?B signaling regulates myelination in the CNS. Front Mol Neurosci 2014; 7: 47.
    • (2014) Front Mol Neurosci , vol.7 , pp. 47
    • Blank, T.1    Prinz, M.2
  • 39
    • 0035873486 scopus 로고    scopus 로고
    • RNA-dependent protein kinase PKR is required for activation of NF-kappa B by IFN-gamma in a STAT1-independent pathway
    • Deb A, Haque SJ, Mogensen T, Silverman RH, Williams BR. RNA-dependent protein kinase PKR is required for activation of NF-kappa B by IFN-gamma in a STAT1-independent pathway. J Immunol 2001; 166: 6170-6180.
    • (2001) J Immunol , vol.166 , pp. 6170-6180
    • Deb, A.1    Haque, S.J.2    Mogensen, T.3    Silverman, R.H.4    Williams, B.R.5
  • 40
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination:the control of NF-kB activity
    • Karin M, Ben-Neriah Y. Phosphorylation meets ubiquitination:the control of NF-kB activity. Annu Rev Immunol 2000; 18: 621-663.
    • (2000) Annu Rev Immunol , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 42
    • 33344476184 scopus 로고    scopus 로고
    • CFLIP regulation of lymphocyte activation and development
    • Budd RC, Yeh WC, Tschopp J. cFLIP regulation of lymphocyte activation and development. Nat Rev Immunol 2006; 6: 196-204.
    • (2006) Nat Rev Immunol , vol.6 , pp. 196-204
    • Budd, R.C.1    Yeh, W.C.2    Tschopp, J.3
  • 44
    • 33644516274 scopus 로고    scopus 로고
    • C5b-9 terminal complex protects oligodendrocytes from apoptotic cell death by inhibiting caspase-8 processing and up-regulating FLIP
    • Cudrici C, Niculescu F, Jensen T, Zafranskaia E, Fosbrink M, Rus V et al. C5b-9 terminal complex protects oligodendrocytes from apoptotic cell death by inhibiting caspase-8 processing and up-regulating FLIP. J Immunol 2006; 176: 3173-3180.
    • (2006) J Immunol , vol.176 , pp. 3173-3180
    • Cudrici, C.1    Niculescu, F.2    Jensen, T.3    Zafranskaia, E.4    Fosbrink, M.5    Rus, V.6
  • 45
    • 34548434392 scopus 로고    scopus 로고
    • Chronic interleukin-1beta expression in mouse brain leads to leukocyte infiltration and neutrophilindependent blood brain barrier permeability without overt neurodegeneration
    • Shaftel SS, Carlson TJ, Olschowka JA, Kyrkanides S, Matousek SB, O'Banion MK. Chronic interleukin-1beta expression in mouse brain leads to leukocyte infiltration and neutrophilindependent blood brain barrier permeability without overt neurodegeneration. J Neurosci 2007; 27: 9301-9309.
    • (2007) J Neurosci , vol.27 , pp. 9301-9309
    • Shaftel, S.S.1    Carlson, T.J.2    Olschowka, J.A.3    Kyrkanides, S.4    Matousek, S.B.5    O'Banion, M.K.6
  • 46
    • 42649084052 scopus 로고    scopus 로고
    • The role of interleukin-1 in neuroinflammation and Alzheimer disease: An evolving perspective
    • Shaftel SS, Griffin WS, O'Banion MK. The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective. J Neuroinflammation 2008; 5: 7.
    • (2008) J Neuroinflammation , vol.5 , pp. 7
    • Shaftel, S.S.1    Griffin, W.S.2    O'Banion, M.K.3
  • 47
    • 34249899174 scopus 로고    scopus 로고
    • Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology
    • Shaftel SS, Kyrkanides S, Olschowka JA, Miller JN, Johnson RE, O'Banion MK. Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology. J Clin Invest 2007; 117: 1595-1604.
    • (2007) J Clin Invest , vol.117 , pp. 1595-1604
    • Shaftel, S.S.1    Kyrkanides, S.2    Olschowka, J.A.3    Miller, J.N.4    Johnson, R.E.5    O'Banion, M.K.6
  • 48
    • 84876001820 scopus 로고    scopus 로고
    • Oligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis
    • Lin W, Lin Y, Li J, Fenstermaker AG, Way SW, Clayton B et al. Oligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis. J Neurosci 2013; 33: 5980-5991.
    • (2013) J Neurosci , vol.33 , pp. 5980-5991
    • Lin, W.1    Lin, Y.2    Li, J.3    Fenstermaker, A.G.4    Way, S.W.5    Clayton, B.6
  • 49
    • 1142275268 scopus 로고    scopus 로고
    • TRADD interacts with STAT1-alpha and influences interferon-gamma signaling
    • Wesemann DR, Qin H, Kokorina N, Benveniste EN. TRADD interacts with STAT1-alpha and influences interferon-gamma signaling. Nat Immunol 2004; 5: 199-207.
    • (2004) Nat Immunol , vol.5 , pp. 199-207
    • Wesemann, D.R.1    Qin, H.2    Kokorina, N.3    Benveniste, E.N.4
  • 50
    • 29444439948 scopus 로고    scopus 로고
    • Differential effects of TNF-alpha and IFN-gamma on gene transcription mediated by NF-kappaB-Stat1 interactions
    • Ganster RW, Guo Z, Shao L, Geller DA. Differential effects of TNF-alpha and IFN-gamma on gene transcription mediated by NF-kappaB-Stat1 interactions. J Interferon Cytokine Res 2005; 25: 707-719.
    • (2005) J Interferon Cytokine Res , vol.25 , pp. 707-719
    • Ganster, R.W.1    Guo, Z.2    Shao, L.3    Geller, D.A.4
  • 51
    • 84870327804 scopus 로고    scopus 로고
    • JAK kinases are required for the bacterial RNA and poly I:C induced tyrosine phosphorylation of PKR
    • Bleiblo F, Michael P, Brabant D, Ramana CV, Tai T, Saleh M et al. JAK kinases are required for the bacterial RNA and poly I:C induced tyrosine phosphorylation of PKR. Int J Clin Exp Med 2013; 6: 16-25.
    • (2013) Int J Clin Exp Med , vol.6 , pp. 16-25
    • Bleiblo, F.1    Michael, P.2    Brabant, D.3    Ramana, C.V.4    Tai, T.5    Saleh, M.6
  • 53
    • 0037079142 scopus 로고    scopus 로고
    • The unfolded protein response modulates disease severity in Pelizaeus-Merzbacher disease
    • Southwood CM, Garbern J, Jiang W, Gow A. The unfolded protein response modulates disease severity in Pelizaeus-Merzbacher disease. Neuron 2002; 36: 585-596.
    • (2002) Neuron , vol.36 , pp. 585-596
    • Southwood, C.M.1    Garbern, J.2    Jiang, W.3    Gow, A.4
  • 54
    • 0041828486 scopus 로고    scopus 로고
    • Cellular FLICE-inhibitory protein: An attractive therapeutic target
    • Micheau O. Cellular FLICE-inhibitory protein: an attractive therapeutic target? Expert Opin Ther Targets 2003; 7: 559-573.
    • (2003) Expert Opin Ther Targets , vol.7 , pp. 559-573
    • Micheau, O.1
  • 55
    • 0029671318 scopus 로고    scopus 로고
    • Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE)
    • Ferber IA, Brocke S, Taylor-Edwards C, Ridgway W, Dinisco C, Steinman L et al. Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE). J Immunol 1996; 156: 5-7.
    • (1996) J Immunol , vol.156 , pp. 5-7
    • Ferber, I.A.1    Brocke, S.2    Taylor-Edwards, C.3    Ridgway, W.4    Dinisco, C.5    Steinman, L.6
  • 56
    • 0030587910 scopus 로고    scopus 로고
    • IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
    • Willenborg DO, Fordham S, Bernard CC, Cowden WB, Ramshaw IA. IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. J Immunol 1996; 157: 3223-3227.
    • (1996) J Immunol , vol.157 , pp. 3223-3227
    • Willenborg, D.O.1    Fordham, S.2    Bernard, C.C.3    Cowden, W.B.4    Ramshaw, I.A.5
  • 57
    • 0035423415 scopus 로고    scopus 로고
    • Intrathecal delivery of IFN-gamma protects C57BL/6 mice from chronic-progressive experimental autoimmune encephalomyelitis by increasing apoptosis of central nervous system-infiltrating lymphocytes
    • Furlan R, Brambilla E, Ruffini F, Poliani PL, Bergami A, Marconi PC et al. Intrathecal delivery of IFN-gamma protects C57BL/6 mice from chronic-progressive experimental autoimmune encephalomyelitis by increasing apoptosis of central nervous system-infiltrating lymphocytes. J Immunol 2001; 167: 1821-1829.
    • (2001) J Immunol , vol.167 , pp. 1821-1829
    • Furlan, R.1    Brambilla, E.2    Ruffini, F.3    Poliani, P.L.4    Bergami, A.5    Marconi, P.C.6
  • 59
    • 0023221133 scopus 로고
    • Treatment of multiple sclerosis with gamma interferon: Exacerbations associated with activation of the immune system
    • Panitch HS, Hirsch RL, Schindler J, Johnson KP. Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system. Neurology 1987; 37: 1097-1102.
    • (1987) Neurology , vol.37 , pp. 1097-1102
    • Panitch, H.S.1    Hirsch, R.L.2    Schindler, J.3    Johnson, K.P.4
  • 60
    • 0032419459 scopus 로고    scopus 로고
    • Interferon-gamma in progression to chronic demyelination and neurological deficit following acute EAE
    • Renno T, Taupin V, Bourbonniere L, Verge G, Tran E, De Simone R et al. Interferon-gamma in progression to chronic demyelination and neurological deficit following acute EAE. Mol Cell Neurosci 1998; 12: 376-389.
    • (1998) Mol Cell Neurosci , vol.12 , pp. 376-389
    • Renno, T.1    Taupin, V.2    Bourbonniere, L.3    Verge, G.4    Tran, E.5    De Simone, R.6
  • 61
    • 0000854861 scopus 로고
    • Growth of a rat neuroblastoma cell line in serum-free supplemented medium
    • Bottenstein JE, Sato GH. Growth of a rat neuroblastoma cell line in serum-free supplemented medium. Proc Natl Acad Sci USA 1979; 76: 514-517.
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 514-517
    • Bottenstein, J.E.1    Sato, G.H.2
  • 62
    • 73149097207 scopus 로고    scopus 로고
    • STAT1/IRF-1 signaling pathway mediates the injurious effect of interferon-gamma on oligodendrocyte progenitor cells
    • Wang Y, Ren Z, Tao D, Tilwalli S, Goswami R, Balabanov R. STAT1/IRF-1 signaling pathway mediates the injurious effect of interferon-gamma on oligodendrocyte progenitor cells. Glia 2010; 58: 195-208.
    • (2010) Glia , vol.58 , pp. 195-208
    • Wang, Y.1    Ren, Z.2    Tao, D.3    Tilwalli, S.4    Goswami, R.5    Balabanov, R.6
  • 63
    • 0035949704 scopus 로고    scopus 로고
    • Delivery of the Cre recombinase by a self-deleting lentiviral vector: Efficient gene targeting in vivo
    • Pfeifer A, Brandon EP, Kootstra N, Gage FH, Verma IM. Delivery of the Cre recombinase by a self-deleting lentiviral vector: efficient gene targeting in vivo. Proc Natl Acad Sci USA 2001; 98: 11450-11455.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 11450-11455
    • Pfeifer, A.1    Brandon, E.P.2    Kootstra, N.3    Gage, F.H.4    Verma, I.M.5
  • 64
    • 64749107970 scopus 로고    scopus 로고
    • Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors
    • Kutner RH, Zhang XY, Reiser J. Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors. Nat Protoc 2009; 4: 495-505.
    • (2009) Nat Protoc , vol.4 , pp. 495-505
    • Kutner, R.H.1    Zhang, X.Y.2    Reiser, J.3
  • 65
    • 33846470670 scopus 로고    scopus 로고
    • Controlled expression of transgenes introduced by in vivo electroporation
    • Matsuda T, Cepko CL. Controlled expression of transgenes introduced by in vivo electroporation. Proc Natl Acad Sci USA 2007; 104: 1027-1032.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 1027-1032
    • Matsuda, T.1    Cepko, C.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.