Activation of endoplasmic reticulum stress is involved in the activity of icariin against human lung adenocarcinoma cells

Apoptosis

Volumn 20, Issue 9, 2015, Pages 1229-1241

  Di, Shouyin ^a   Fan, Chongxi ^a   Yang, Yang ^b   Jiang, Shuai ^b   Liang, Miaomiao ^c   Wu, Guiling ^b   Wang, Bodong ^b   Xin, Zhenlong ^b   Hu, Wei ^b   Zhu, Yifang ^a   Li, Weimiao ^a   Zhou, Yongan ^a   Li, Xiaofei ^a   Yan, Xiaolong ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Endoplasmic reticulum stress; Human lung adenocarcinoma cells; Icariin; PERK siRNA; Thapsigargin

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CASPASE 3; GLUCOSE REGULATED PROTEIN 78; GLUTATHIONE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; ICARIIN; INITIATION FACTOR 2ALPHA; PEPTIDES AND PROTEINS; PROTEIN BCL 2; PROTEIN PERK; PUMA PROTEIN; THAPSIGARGIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN; ENZYME INHIBITOR; FLAVONOID; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL LINE; CANCER INHIBITION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR XENOGRAFT; UPREGULATION; ADENOCARCINOMA; ANIMAL; CELL SURVIVAL; DRUG EFFECTS; LUNG TUMOR; MALE; METABOLISM; NUDE MOUSE; SIGNAL TRANSDUCTION; TUMOR CELL LINE; XENOGRAFT;

ADENOCARCINOMA; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITORS; FLAVONOIDS; GLUTATHIONE; HETEROGRAFTS; HUMANS; LUNG NEOPLASMS; MALE; MICE, NUDE; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; THAPSIGARGIN;

EID: 84938956239     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-015-1142-0     Document Type: Article

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