Icariin potentiates the antitumor activity of gemcitabine in gallbladder cancer by suppressing NF-κB

Acta Pharmacologica Sinica

Volumn 34, Issue 2, 2013, Pages 301-308

  Zhang, Dian Cai ^a   Liu, Jin Long ^a   Ding, Yong Bin ^a   Xia, Jian Guo ^a   Chen, Guo Yu ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

apoptosis; cancer xenograft model; cell cycle arrest; gallbladder cancer; GBC SD cell; gemcitabine; icariin; NF B; SGC 996 cell; synergistic effect

Indexed keywords

CASPASE 3; GEMCITABINE; ICARIIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BCL 2; PROTEIN BCL XL; SURVIVIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; COLORIMETRY; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG POTENTIATION; DRUG SENSITIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GALLBLADDER CANCER; GROWTH INHIBITION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; TUMOR VOLUME; TUMOR XENOGRAFT; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; DEOXYCYTIDINE; DRUG SYNERGISM; DRUGS, CHINESE HERBAL; FEMALE; FLAVONOIDS; GALLBLADDER; GALLBLADDER NEOPLASMS; HUMANS; MICE; MICE, INBRED BALB C; NF-KAPPA B;

EID: 84873547035     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2012.162     Document Type: Article

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