-
1
-
-
0023676068
-
Oligomeric structure of p21 ras proteins as determined by radiation inactivation
-
Santos E, Nebreda AR, Bryan T, Kempner ES (1988) Oligomeric structure of p21 ras proteins as determined by radiation inactivation. J Biol Chem 263(20): 9853-9858.
-
(1988)
J Biol Chem
, vol.263
, Issue.20
, pp. 9853-9858
-
-
Santos, E.1
Nebreda, A.R.2
Bryan, T.3
Kempner, E.S.4
-
2
-
-
0034635502
-
Formation of the Ras dimer is essential for Raf-1 activation
-
Inouye K, Mizutani S, Koide H, Kaziro Y (2000) Formation of the Ras dimer is essential for Raf-1 activation. J Biol Chem 275(6): 3737-3740.
-
(2000)
J Biol Chem
, vol.275
, Issue.6
, pp. 3737-3740
-
-
Inouye, K.1
Mizutani, S.2
Koide, H.3
Kaziro, Y.4
-
3
-
-
0037455589
-
Direct visualization of Ras proteins in spatially distinct cell surface microdomains
-
Prior IA, Muncke C, Parton RG, Hancock JF (2003) Direct visualization of Ras proteins in spatially distinct cell surface microdomains. J Cell Biol 160(2): 165-170.
-
(2003)
J Cell Biol
, vol.160
, Issue.2
, pp. 165-170
-
-
Prior, I.A.1
Muncke, C.2
Parton, R.G.3
Hancock, J.F.4
-
4
-
-
34547561587
-
Plasma membrane nanoswitches generate high-fidelity Ras signal transduction
-
Tian T, et al. (2007) Plasma membrane nanoswitches generate high-fidelity Ras signal transduction. Nat Cell Biol 9(8): 905-914.
-
(2007)
Nat Cell Biol
, vol.9
, Issue.8
, pp. 905-914
-
-
Tian, T.1
-
5
-
-
27344456331
-
H-ras, K-ras, and inner plasma membrane raft proteins operate in nanoclusters with differential dependence on the actin cytoskeleton
-
Plowman SJ, Muncke C, Parton RG, Hancock JF (2005) H-ras, K-ras, and inner plasma membrane raft proteins operate in nanoclusters with differential dependence on the actin cytoskeleton. Proc Natl Acad Sci USA 102(43): 15500-15505.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.43
, pp. 15500-15505
-
-
Plowman, S.J.1
Muncke, C.2
Parton, R.G.3
Hancock, J.F.4
-
6
-
-
84867030014
-
N-Ras forms dimers at POPC membranes
-
Güldenhaupt J, et al. (2012) N-Ras forms dimers at POPC membranes. Biophys J 103(7): 1585-1593.
-
(2012)
Biophys J
, vol.103
, Issue.7
, pp. 1585-1593
-
-
Güldenhaupt, J.1
-
7
-
-
84896840047
-
H-Ras forms dimers on membrane surfaces via a protein-protein interface
-
Lin WC, et al. (2014) H-Ras forms dimers on membrane surfaces via a protein-protein interface. Proc Natl Acad Sci USA 111(8): 2996-3001.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, Issue.8
, pp. 2996-3001
-
-
Lin, W.C.1
-
8
-
-
84936847680
-
GTP-dependent K-ras dimerization
-
Muratcioglu S, et al. (2015) GTP-dependent K-ras dimerization. Structure 23(7): 1325-1335.
-
(2015)
Structure
, vol.23
, Issue.7
, pp. 1325-1335
-
-
Muratcioglu, S.1
-
9
-
-
0035328521
-
Active Ras induces heterodimerization of cRaf and BRaf
-
Weber CK, Slupsky JR, Kalmes HA, Rapp UR (2001) Active Ras induces heterodimerization of cRaf and BRaf. Cancer Res 61(9): 3595-3598.
-
(2001)
Cancer Res
, vol.61
, Issue.9
, pp. 3595-3598
-
-
Weber, C.K.1
Slupsky, J.R.2
Kalmes, H.A.3
Rapp, U.R.4
-
10
-
-
77949732073
-
RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF
-
Poulikakos PI, Zhang C, Bollag G, Shokat KM, Rosen N (2010) RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF. Nature 464(7287): 427-430.
-
(2010)
Nature
, vol.464
, Issue.7287
, pp. 427-430
-
-
Poulikakos, P.I.1
Zhang, C.2
Bollag, G.3
Shokat, K.M.4
Rosen, N.5
-
11
-
-
70349438995
-
A dimerization-dependent mechanism drives RAF catalytic activation
-
Rajakulendran T, Sahmi M, Lefrançois M, Sicheri F, Therrien M (2009) A dimerization-dependent mechanism drives RAF catalytic activation. Nature 461(7263): 542-545.
-
(2009)
Nature
, vol.461
, Issue.7263
, pp. 542-545
-
-
Rajakulendran, T.1
Sahmi, M.2
Lefrançois, M.3
Sicheri, F.4
Therrien, M.5
-
12
-
-
84937957816
-
Ras-GTP dimers activate the Mitogen- Activated Protein Kinase (MAPK) pathway
-
Nan X, et al. (2015) Ras-GTP dimers activate the Mitogen- Activated Protein Kinase (MAPK) pathway. Proc Natl Acad Sci USA 112(26): 7996-8001.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, Issue.26
, pp. 7996-8001
-
-
Nan, X.1
-
13
-
-
84887425345
-
Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling
-
Nan X, et al. (2013) Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling. Proc Natl Acad Sci USA 110(46): 18519-18524.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.46
, pp. 18519-18524
-
-
Nan, X.1
-
14
-
-
0036325229
-
Structural determinants of Ras-Raf interaction analyzed in live cells
-
Bondeva T, Balla A, Várnai P, Balla T (2002) Structural determinants of Ras-Raf interaction analyzed in live cells. Mol Biol Cell 13(7): 2323-2333.
-
(2002)
Mol Biol Cell
, vol.13
, Issue.7
, pp. 2323-2333
-
-
Bondeva, T.1
Balla, A.2
Várnai, P.3
Balla, T.4
-
15
-
-
84930667920
-
Electron microscopy. 2.2 Å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor
-
Bartesaghi A, et al. (2015) Electron microscopy. 2.2 ? resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor. Science 348(6239): 1147-1151.
-
(2015)
Science
, vol.348
, Issue.6239
, pp. 1147-1151
-
-
Bartesaghi, A.1
-
16
-
-
34250666273
-
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
-
Whorton MR, et al. (2007) A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein. Proc Natl Acad Sci USA 104(18): 7682-7687.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.18
, pp. 7682-7687
-
-
Whorton, M.R.1
-
17
-
-
84930221645
-
Oncogenic and RASopathyassociated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site
-
Mazhab-Jafari MT, et al. (2015) Oncogenic and RASopathyassociated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site. Proc Natl Acad Sci USA 112(21): 6625-6630.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, Issue.21
, pp. 6625-6630
-
-
Mazhab-Jafari, M.T.1
-
18
-
-
84896090174
-
Dragging ras back in the ring
-
Stephen AG, Esposito D, Bagni RK, McCormick F (2014) Dragging ras back in the ring. Cancer Cell 25(3): 272-281.
-
(2014)
Cancer Cell
, vol.25
, Issue.3
, pp. 272-281
-
-
Stephen, A.G.1
Esposito, D.2
Bagni, R.K.3
McCormick, F.4
-
19
-
-
84908491115
-
Drugging the undruggable RAS: Mission possible?
-
Cox AD, Fesik SW, Kimmelman AC, Luo J, Der CJ (2014) Drugging the undruggable RAS: Mission possible? Nat Rev Drug Discov 13(11): 828-851.
-
(2014)
Nat Rev Drug Discov
, vol.13
, Issue.11
, pp. 828-851
-
-
Cox, A.D.1
Fesik, S.W.2
Kimmelman, A.C.3
Luo, J.4
Der, C.J.5
|