Glucuronidation of estrone and 16α-hydroxyestrone by human UGT enzymes: The key roles of UGT1A10 and UGT2B7

Journal of Steroid Biochemistry and Molecular Biology

Volumn 154, Issue , 2015, Pages 104-111

  Kallionpää, Roope A ^a,b   Järvinen, Erkka ^a   Finel, Moshe ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

Author keywords

16 Hydroxyestrone conjugation; Estrone glucuronidation; Extrahepatic glucuronidation; Intestine microsomes; UGT1A10; UGT2B7

Indexed keywords

16ALPHA HYDROXYESTRONE; ESTRONE; ESTRONE GLUCURONIDE; GLUCURONOSYLTRANSFERASE 1A10; GLUCURONOSYLTRANSFERASE 2B7; 16-HYDROXYESTRONE; BILIRUBIN URIDINE-DIPHOSPHOGLUCURONOSYL TRANSFERASE 1A10; ESTRONE DERIVATIVE; GLUCURONIDE; GLUCURONOSYLTRANSFERASE; UGT2B7 PROTEIN, HUMAN;

ARTICLE; BIOSYNTHESIS; CATALYSIS; CONJUGATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME KINETICS; GLUCURONIDATION; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIVER MICROSOME; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SUBSTRATE CONCENTRATION; ENZYME SPECIFICITY; ENZYMOLOGY; INTESTINE; KINETICS; METABOLISM;

ESTRONE; GLUCURONIDES; GLUCURONOSYLTRANSFERASE; HYDROXYESTRONES; INTESTINES; KINETICS; MICROSOMES, LIVER; SUBSTRATE SPECIFICITY;

EID: 84938914503     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2015.07.013     Document Type: Article

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