Assay reproducibility and interindividual variation for 15 serum estrogens and estrogen metabolites measured by liquid chromatography-tandem mass spectrometry

Cancer Epidemiology Biomarkers and Prevention

Volumn 23, Issue 12, 2014, Pages 2649-2657

  Fuhrman, Barbara J ^a,d   Xu, Xia ^b   Falk, Roni T ^a   Dallal, Cher M ^a,e   Veenstra, Timothy D ^b,f   Keefer, Larry K ^c   Graubard, Barry I ^a   Brinton, Louise A ^a   Ziegler, Regina G ^a   Gierach, Gretchen L ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^e UNIVERSITY OF MARYLAND   (United States)

^f C2N Diagnostics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ESTROGEN; ESTRONE;

ADULT; ARTICLE; CORRELATION COEFFICIENT; ESTROGEN BLOOD LEVEL; ESTROGEN METABOLISM; FEMALE; HUMAN; LIQUID CHROMATOGRAPHY; MALE; POSTMENOPAUSE; PREMENOPAUSE; REPRODUCIBILITY; TANDEM MASS SPECTROMETRY; METABOLISM; PROCEDURES;

CHROMATOGRAPHY, LIQUID; ESTROGENS; FEMALE; HUMANS; MALE; POSTMENOPAUSE; PREMENOPAUSE; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

EID: 84919394188     PISSN: 10559965     EISSN: 15387755     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-14-0438     Document Type: Article

References (18)

1. Eliassen AH, Hankinson SE Endogenous hormone levels and risk of breast, endometrial and ovarian cancers: prospective studies. Adv Exp Med Biol 2008; 630: 148-65.
2. Risbridger GP, Davis ID, Birrell S.N., Tilley WD. Breast and prostate cancer: more similar than different. Nat Rev Cancer 2010; 10: 205-12.
3. Depue RH, Pike MC, Henderson BE Estrogen exposure during gestation and risk of testicular cancer. J Natl Cancer Inst 1983; 71: 1151-5.
4. Jefcoate CR, Liehr JG, Santen R.J., Sutter TR, Yager JD, Yue W, et al Tissue-specific synthesis and oxidative metabolism of estrogens. J Natl Cancer Inst Monogr 2000:95-112.
5. Raftogianis R, Creveling C, Weinshilboum R., Weisz J. Estrogen metabolism by conjugation. J Natl Cancer Inst Monogr 2000:113-24.
6. Sasano H, Suzuki T, Miki Y., Moriya T. Intracrinology of estrogens and androgens in breast carcinoma. J Steroid Biochem Mol Biol 2008; 108:181-5.
7. Zhu B, Han G, Shim J., Wen Y, Jiang X. Quantitative structure-activity relationship of various endogenous estrogen metabolites for human estrogen receptor alpha and beta subtypes: insights into the structural determinants favoring a differential subtype binding. Endocrinology 2006; 147: 4132-50.
8. Cavalieri E, Frenkel K, Liehr J.G., Rogan E., Roy D. Estrogens as endogenous genotoxic agents-DNA adducts and mutations. J Natl Cancer Inst Monogr 2000:75-93.
9. Yager JD, Davidson NE Estrogen carcinogenesis in breast cancer. N Engl J Med 2006; 354: 270-82.
10. Falk RT, Xu X, Keefer L., Veenstra TD, Ziegler RG. A liquid chromatog-raphy-mass spectrometry method for the simultaneous measurement of 15 urinary estrogens and estrogen metabolites: assay reproduc-ibility and interindividual variability. Cancer Epidemiol Biomarkers Prev 2008; 17: 3411-8.
11. Xu X, Roman JM, Issaq H.J., Keefer LK, Veenstra TD, Ziegler RG. Quantitative measurement of endogenous estrogens and estrogen metabolites in human serum by liquid chromatography-tandem mass spectrometry. Anal Chem 2007; 79: 7813-21.
12. Fuhrman BJ, Schairer C, Gail M.H., Boyd-Morin J, Xu X, Sue L.Y., et al. Estrogen metabolism and risk of breast cancer in postmenopausal women. J Natl Cancer Inst 2012; 104: 326-39.
13. Falk RT, Brinton LA, Dorgan J.F., Fuhrman BJ, Veenstra TD, Xu X, et al Relationship of serum estrogens and estrogen metabolites to post-menopausal breast cancer risk: a nested case-control study. Breast Cancer Res 2013; 15:R34.
14. Dallal CM, Tice JA, Buist D.S., Bauer DC, Lacey JV Jr, Cauley JA, et al. Estrogen metabolism and breast cancer risk among postmenopausal women: a case-cohort study within B~FIT. Carcinogenesis 2014; 35: 346-55.
15. Gail MH, Fears TR, Hoover R.N., Chandler DW, Donaldson JL, Hyer MB, et al Reproducibility studies and interlaboratory concordance for assays of serum hormone levels: estrone, estradiol, estrone sulfate, and progesterone. Cancer Epidemiol Biomarkers Prev 1996; 5: 835-44.
16. Eliassen AH, Ziegler RG, Rosner B, Veenstra T.D., Roman JM, Xu X, et al. Reproducibility of fifteen urinary estrogens and estrogen metabolites over a 2- to 3-year period in premenopausal women. Cancer Epidemiol Biomarkers Prev 2009; 18: 2860-8.
17. Stanczyk FZ, Lee JS, Santen RJ Standardization of steroid hormone assays: why, how, and when? Cancer Epidemiol Biomarkers Prev 2007; 16: 1713-9.
18. Rosner W, Hankinson SE, Sluss P.M., Vesper HW, Wierman ME. Challenges to the measurement of estradiol: an endocrine society position statement. J Clin Endocrinol Metab 2013; 98: 1376-87.