Molecular basis and drug sensitivity of the delayed rectifier (IKr) in the fish heart

Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology

Volumn 176-177, Issue , 2015, Pages 44-51

  Hassinen, Minna ^a   Haverinen, Jaakko ^a   Vornanen, Matti ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Abbreviations AP action potential; CHO cells Chinese hamster ovary cells; HR heart rate; RMP resting membrane potential; UTR untranslated region

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; 2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; COMPLEMENTARY DNA; DELAYED RECTIFIER POTASSIUM CHANNEL; POTASSIUM CHANNEL HERG; TERFENADINE; VERAPAMIL; ERG1 POTASSIUM CHANNEL; FISH PROTEIN; MESSENGER RNA; POTASSIUM; POTASSIUM CHANNEL BLOCKING AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHO CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRUCIAN CARP; CURRENT DENSITY; DRUG SENSITIVITY; FEMALE; HEART ATRIUM; HEART MUSCLE CELL; IC50; MALE; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; AMINO ACID SEQUENCE; ANIMAL; ANIMAL MODEL; ANTAGONISTS AND INHIBITORS; CARDIAC MUSCLE; CARP; CRICETULUS; DOSE RESPONSE; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; HEART; MEMBRANE POTENTIAL; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; SPECIES DIFFERENCE;

CARASSIUS; CARASSIUS CARASSIUS; CRICETULUS GRISEUS; MAMMALIA; PISCES;

AMINO ACID SEQUENCE; ANIMALS; CARPS; CHO CELLS; CLONING, MOLECULAR; CRICETULUS; DELAYED RECTIFIER POTASSIUM CHANNELS; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHER-A-GO-GO POTASSIUM CHANNELS; FEMALE; FISH PROTEINS; HEART; MALE; MEMBRANE POTENTIALS; MODELS, ANIMAL; MOLECULAR SEQUENCE DATA; MYOCARDIUM; POTASSIUM; POTASSIUM CHANNEL BLOCKERS; RNA, MESSENGER; SPECIES SPECIFICITY; TRANSFECTION;

EID: 84938881927     PISSN: 15320456     EISSN: 18781659     Source Type: Journal    
DOI: 10.1016/j.cbpc.2015.07.005     Document Type: Article

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