-
1
-
-
0003443746
-
-
Third edition. Sinauer Associates, Inc. Sunderland, MA
-
Hille B: Ion Channels of Excitable Membranes, Third edition. Sinauer Associates, Inc. Sunderland, MA, 2001.
-
(2001)
Ion Channels of Excitable Membranes
-
-
Hille, B.1
-
3
-
-
0028914969
-
A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome
-
Curran ME, Splawski I, Timothy KW, Vincent GM, Green ED, Keating MT: A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome. Cell 1995;80:795-803.
-
(1995)
Cell
, vol.80
, pp. 795-803
-
-
Curran, M.E.1
Splawski, I.2
Timothy, K.W.3
Vincent, G.M.4
Green, E.D.5
Keating, M.T.6
-
4
-
-
0029847602
-
Multiple mechanisms in the long-QT syndrome
-
Roden DM, Lazzara R, Rosen M, Schwartz PJ, Towbin J, Vincent GM: Multiple mechanisms in the long-QT syndrome. Circulation 1996;94:1996-2012.
-
(1996)
Circulation
, vol.94
, pp. 1996-2012
-
-
Roden, D.M.1
Lazzara, R.2
Rosen, M.3
Schwartz, P.J.4
Towbin, J.5
Vincent, G.M.6
-
5
-
-
0029002969
-
A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel
-
Sanguinetti MC, Jiang C, Curran ME, Keating MT: A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel. Cell 1995;81:299-307.
-
(1995)
Cell
, vol.81
, pp. 299-307
-
-
Sanguinetti, M.C.1
Jiang, C.2
Curran, M.E.3
Keating, M.T.4
-
6
-
-
0029925480
-
+-channel dysfunction in an inherited cardiac arrhythmia
-
DOI 10.1073/pnas.93.5.2208
-
Sanguinetti MC, Curran ME, Spector PS, Keating MT: Spectrum of HERG K F-channel dysfunction in an inherited cardiac arrhythmia. PNAS 1996;93; 2208-2212. (Pubitemid 26079907)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.5
, pp. 2208-2212
-
-
Sanguinetti, M.C.1
Curran, M.E.2
Spector, P.S.3
Keating, M.T.4
-
7
-
-
0029761822
-
HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine
-
Roy M-L, Dumaine R, Brown AM: HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine. Circulation 1996;94: 817-823. (Pubitemid 26289240)
-
(1996)
Circulation
, vol.94
, Issue.4
, pp. 817-823
-
-
Roy, M.-L.1
Dumaine, R.2
Brown, A.M.3
-
8
-
-
0032783924
-
Cardiac ion channels and antihistamines: Possible mechanisms of cardiotoxicity
-
Taglialatela M, Castaldo P, Pannaccione A, Giorgio G, Genovese A, Marone G, Annunziato L: Cardiac ion channels and antihistamines: possible mechanisms of cardiotoxicity. Clin Exp Allergy 1999;29:182-189. (Pubitemid 29333355)
-
(1999)
Clinical and Experimental Allergy, Supplement
, vol.29
, Issue.3
, pp. 182-189
-
-
Taglialatela, M.1
Castaldo, P.2
Pannaccione, A.3
Giorgio, G.4
Genovese, A.5
Marone, G.6
Annunziato, L.7
-
9
-
-
0034231822
-
Drugs that prolong QT interval as an unwanted effect: Assessing their likelihood of inducing hazardous cardiac dysrhythmias
-
Cavero I, Mestre M, Guillon JM, Crumb W: Drugs that prolong QT interval as an unwanted effect: assessing their likelihood of inducing hazardous cardiac dysrhythmias. Expert Opin Pharmacother 2000;1:947-973.
-
(2000)
Expert Opin Pharmacother
, vol.1
, pp. 947-973
-
-
Cavero, I.1
Mestre, M.2
Guillon, J.M.3
Crumb, W.4
-
10
-
-
42149193214
-
High-throughput electrophysiology: An emerging paradigm for ion channel screening and physiology
-
Dunlop J, Bowlby M, Peri R, Vasilyev D, Arias R: High-throughput electrophysiology: an emerging paradigm for ion channel screening and physiology. Nat Rev Drug Discov 2008;7:358-368.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 358-368
-
-
Dunlop, J.1
Bowlby, M.2
Peri, R.3
Vasilyev, D.4
Arias, R.5
-
11
-
-
0019441262
-
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
-
DOI 10.1007/BF00656997
-
Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ: Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflueg Arch 1981;391:85-100. (Pubitemid 11012976)
-
(1981)
Pflugers Archiv European Journal of Physiology
, vol.391
, Issue.2
, pp. 85-100
-
-
Hamill, O.P.1
Marty, A.2
Neher, E.3
-
12
-
-
0042895988
-
High throughput ion channel pharmacology: Planar array based voltage clamp
-
Kiss L, Bennett PB, Uebele VN, Koblan KS, Kane SA, Neagle B, Schroeder K: High throughput ion channel pharmacology: planar array based voltage clamp. Assay Drug Dev Technol 2003;1:127-135.
-
(2003)
Assay Drug Dev Technol
, vol.1
, pp. 127-135
-
-
Kiss, L.1
Bennett, P.B.2
Uebele, V.N.3
Koblan, K.S.4
Kane, S.A.5
Neagle, B.6
Schroeder, K.7
-
13
-
-
20144389310
-
Identifying modulators of hERG channel activity using the PatchXpress planar patch clamp
-
Dubin AE, Nasser N, Rohrbacher J, Hermans AN, Marrannes R, Grantham C, van Rossem K, Cik M, Chaplan SR, Gallacher D, Xu J, Guia A, Byrne NG, Mathes C: Identifying modulators of hERG channel activity using the PatchXpress planar patch clamp. J Biomol Screen 2005;10:168-181.
-
(2005)
J Biomol Screen
, vol.10
, pp. 168-181
-
-
Dubin, A.E.1
Nasser, N.2
Rohrbacher, J.3
Hermans, A.N.4
Marrannes, R.5
Grantham, C.6
Van Rossem, K.7
Cik, M.8
Chaplan, S.R.9
Gallacher, D.10
Xu, J.11
Guia, A.12
Byrne, N.G.13
Mathes, C.14
-
14
-
-
33748129547
-
Optimisation and validation of a medium-throughput electrophysiology- based hERG assay using IonWorks™ HT
-
DOI 10.1016/j.vascn.2006.02.003, PII S1056871906000207
-
Bridgland-Taylor MH, Hargreaves AC, Easter A, Orme A, Henthorn DC, Ding M, Davis AM, Small BG, Heapy CG, Abi-Gerges N, Persson F, Jacobson I, Sullivan M, Albertson N, Hammond TG, Sullivan E, Valentin JP, Pollard CE: Optimisation and validation of a medium-throughput electrophysiologybased hERG assay using IonWorks HT. J Pharmacol Toxicol Methods 2006; 54:189-199. (Pubitemid 44308866)
-
(2006)
Journal of Pharmacological and Toxicological Methods
, vol.54
, Issue.2
, pp. 189-199
-
-
Bridgland-Taylor, M.H.1
Hargreaves, A.C.2
Easter, A.3
Orme, A.4
Henthorn, D.C.5
Ding, M.6
Davis, A.M.7
Small, B.G.8
Heapy, C.G.9
Abi-Gerges, N.10
Persson, F.11
Jacobson, I.12
Sullivan, M.13
Albertson, N.14
Hammond, T.G.15
Sullivan, E.16
Valentin, J.-P.17
Pollard, C.E.18
-
15
-
-
61849084206
-
Model systems for the discovery and development of antiarrhythmic drugs
-
Nattel S, Duker G, Carlsson L: Model systems for the discovery and development of antiarrhythmic drugs. Prog Biophys Mol Biol 2008;98:328-339.
-
(2008)
Prog Biophys Mol Biol
, vol.98
, pp. 328-339
-
-
Nattel, S.1
Duker, G.2
Carlsson, L.3
-
16
-
-
62649105798
-
Port-a-Patch and Patchliner: High fidelity electrophysiology for secondary screening and safety pharmacology
-
Farre C, Haythornthwaite A, Haarmann C, Stoelzle S, Kreir M, George M, Brüggemann A, Fertig N: Port-a-Patch and Patchliner: high fidelity electrophysiology for secondary screening and safety pharmacology. Comb Chem High Throughput Screen 2009;12:24-37.
-
(2009)
Comb Chem High Throughput Screen
, vol.12
, pp. 24-37
-
-
Farre, C.1
Haythornthwaite, A.2
Haarmann, C.3
Stoelzle, S.4
Kreir, M.5
George, M.6
Brüggemann, A.7
Fertig, N.8
-
18
-
-
0037232042
-
CYTOCENTERING: A novel technique enabling automated cell-by-cell patch clamping with the CYTOPATCH™ chip
-
DOI 10.1080/10606820308254
-
Stett A, Burkhardt C, Weber U, van Stiphout P, Knott T: Cytocentering: a novel technique enabling automated cell-by-cell patch clamping with the CytoPatcḧchip. Receptors Channels 2003;9:59-66. (Pubitemid 36372593)
-
(2003)
Receptors and Channels
, vol.9
, Issue.1
, pp. 59-66
-
-
Stett, A.1
Burkhardt, C.2
Weber, U.3
Van Stiphout, P.4
Knott, T.5
-
19
-
-
83055173552
-
-
German Patent 10 2007 010 843.7-09
-
German Patent 10 2007 010 843.7-09
-
-
-
-
20
-
-
0031982513
-
Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature
-
Zhou ZF, Gong Q, Ye B, Fan Z, Makielski JC, Robertson GA, January CT: Properties of hERG channels stably expressed in HEK293 cells studied at physiological temperature. Biophys J 1998;74:230-241. (Pubitemid 28041752)
-
(1998)
Biophysical Journal
, vol.74
, Issue.1
, pp. 230-241
-
-
Zhou, Z.1
Gong, Q.2
Ye, B.3
Fan, Z.4
Makielski, J.C.5
Robertson, G.A.6
January, C.T.7
-
21
-
-
34548480951
-
Suitability of commonly used excipients for electrophysiological in-vitro safety pharmacology assessment of effects on hERG potassium current and on rabbit Purkinje fiber action potential
-
DOI 10.1016/j.vascn.2007.04.004, PII S1056871907001943, Special Issue: Fourth Annual Focus on Safety Pharmacology
-
Himmel HM: Suitability of commonly used excipients for electrophysiological in-vitro safety pharmacology assessment of effects on hERG potassium current and on rabbit Purkinje fiber action potential. J Pharmacol Toxicol Methods 2007;56:145-158. (Pubitemid 47376970)
-
(2007)
Journal of Pharmacological and Toxicological Methods
, vol.56
, Issue.2
, pp. 145-158
-
-
Himmel, H.M.1
-
22
-
-
22444443481
-
Automated electrophysiology in the preclinical evaluation of drugs for potential QT prolongation
-
DOI 10.1016/j.vascn.2005.04.002, PII S1056871905000493, Second Annual Focus on Safety Pharmacology
-
Guo L, Guthrie H: Automated electrophysiology in the preclinical evaluation of drugs for potential QT prolongation. J Pharmacol Toxicol Methods 2005;52: 123-135. (Pubitemid 41008636)
-
(2005)
Journal of Pharmacological and Toxicological Methods
, vol.52
, Issue.1
, pp. 123-135
-
-
Guo, L.1
Guthrie, H.2
-
23
-
-
0034609833
-
Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties
-
Ertl P, Rohde B, Selzer P: Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties. J Med Chem 2000;43:3714-3717.
-
(2000)
J Med Chem
, vol.43
, pp. 3714-3717
-
-
Ertl, P.1
Rohde, B.2
Selzer, P.3
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