A single conserved residue mediates binding of the ribonucleotide reductase catalytic subunit RRM1 to RRM2 and is essential for mouse development

Molecular and Cellular Biology

Volumn 35, Issue 17, 2015, Pages 2910-2917

  Specks, Julia ^a   Lecona, Emilio ^a   Lopez Contreras, Andrés J ^b   Fernandez Capetillo, Oscar ^a,c  

^a Structural Biology and Biocomputing Programme   (Spain)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c SCIENCE FOR LIFE LABORATORY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

RIBONUCLEOTIDE REDUCTASE; RRM1 PROTEIN; RRM2 PROTEIN; UNCLASSIFIED DRUG; H2AX PROTEIN, MOUSE; HISTONE; MUCIN; MUSCLE PROTEIN; PEPTIDE; PROTEIN BINDING; RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE; RIBONUCLEOTIDE REDUCTASE M2; RRM1 PROTEIN, MOUSE; TFF2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DEVELOPMENT; EMBRYO; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL LINE; CYTOLOGY; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; GENE TARGETING; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; MUTATION;

MAMMALIA; MUS; SACCHAROMYCES CEREVISIAE;

ANIMALS; CELL LINE; EMBRYONIC DEVELOPMENT; EMBRYONIC STEM CELLS; GENE KNOCK-IN TECHNIQUES; HEK293 CELLS; HISTONES; HUMANS; MICE; MICE, INBRED C57BL; MUCINS; MUSCLE PROTEINS; MUTATION; PEPTIDES; PROTEIN BINDING; RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE; RIBONUCLEOTIDE REDUCTASES;

EID: 84938853170     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00475-15     Document Type: Article

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