Imipramine blue halts head and neck cancer invasion through promoting F-box and leucine-rich repeat protein 14-mediated Twist1 degradation

Oncogene

Volumn 35, Issue 18, 2016, Pages 2287-2298

  Yang, W H ^a   Su, Y H ^a   Hsu, W H ^a   Wang, C C ^a,b,c   Arbiser, J L ^d,e   Yang, M H ^a,f  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e ATLANTA VA MEDICAL CENTER   (United States)

^f TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; F BOX PROTEIN; GUANOSINE TRIPHOSPHATASE; IMIPRAMINE BLUE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEUCINE RICH REPEAT KINASE 14; MICRORNA; PROTEIN; PROTEIN SERINE THREONINE KINASE; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; TRANSCRIPTION FACTOR; TWIST1 PROTEIN; UNCLASSIFIED DRUG; FBXL14 PROTEIN, HUMAN; IMIPRAMINE; TWIST RELATED PROTEIN 1; UBIQUITIN PROTEIN LIGASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION; GENE TARGETING; GLIOMA CELL; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR INVASION; TUMOR MICROENVIRONMENT; TUMOR VOLUME; ANIMAL; DRUG EFFECTS; HEAD AND NECK TUMOR; METABOLISM; PATHOLOGY; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE; UBIQUITINATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; EPITHELIAL-MESENCHYMAL TRANSITION; F-BOX PROTEINS; HEAD AND NECK NEOPLASMS; HUMANS; IMIPRAMINE; MICE; NEOPLASM INVASIVENESS; NF-KAPPA B; PROTEOLYSIS; TWIST-RELATED PROTEIN 1; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84938851963     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2015.291     Document Type: Article

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