HMGB1 promotes the activation of NLRP3 and caspase-8 inflammasomes via NF-κB pathway in acute glaucoma

Journal of Neuroinflammation

Volumn 12, Issue 1, 2015, Pages

  Chi, Wei ^a   Chen, Hongrui ^a   Li, Fei ^a   Zhu, Yingting ^a   Yin, Wei ^b   Zhuo, Yehong ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

Acute glaucoma; Caspase 8 inflammasome; HMGB1; NLRP3 inflammasome

Indexed keywords

BETA ACTIN; CASPASE 8; CRYOPYRIN; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; TOBRAMYCIN; CARRIER PROTEIN; NLRP3 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; CLOSED ANGLE GLAUCOMA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; FEMALE; IMMUNOPRECIPITATION; INTRAOCULAR PRESSURE; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ACUTE DISEASE; ANIMAL; C57BL MOUSE; DISEASE MODEL; GLAUCOMA; INJURIES; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; RETINA; SEVERITY OF ILLNESS INDEX;

ACUTE DISEASE; ANIMALS; CARRIER PROTEINS; CASPASE 8; DISEASE MODELS, ANIMAL; FEMALE; GLAUCOMA; HMGB1 PROTEIN; INFLAMMASOMES; INTERLEUKIN-1BETA; INTRAOCULAR PRESSURE; MICE; MICE, INBRED C57BL; NF-KAPPA B; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; RETINA; SEVERITY OF ILLNESS INDEX; SIGNAL TRANSDUCTION;

EID: 84938840185     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-015-0360-2     Document Type: Article

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