Caspase-8 promotes NLRP1/NLRP3 inflammasome activation and IL-1β production in acute glaucoma

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 30, 2014, Pages 11181-11186

  Chi, Wei ^a   Li, Fei ^a   Chen, Hongrui ^a   Wang, Yandong ^a   Zhu, Yingting ^a   Yang, Xuejiao ^a   Zhu, Jie ^b   Wu, Frances ^b   Ouyang, Hong ^b   Ge, Jian ^a   Weinreb, Robert N ^b   Zhang, Kang ^b   Zhuo, Yehong ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Cell apoptosis; Retinal ischemia reperfusion injury

Indexed keywords

CASPASE 3; CASPASE 8; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; TOLL LIKE RECEPTOR 4;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DEATH; CLOSED ANGLE GLAUCOMA; CYTOKINE PRODUCTION; ENZYME ACTIVATION; INTRAOCULAR PRESSURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA GANGLION CELL; RETINA ISCHEMIA; SIGNAL TRANSDUCTION;

CELL APOPTOSIS; RETINAL ISCHEMIA/REPERFUSION INJURY;

ACUTE DISEASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS REGULATORY PROTEINS; CARRIER PROTEINS; CASPASE 1; CASPASE 8; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; EYE PROTEINS; GLAUCOMA; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TOLL-LIKE RECEPTOR 4;

EID: 84904990668     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1402819111     Document Type: Article

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