Herpesvirus Genome Recognition Induced Acetylation of Nuclear IFI16 Is Essential for Its Cytoplasmic Translocation, Inflammasome and IFN-β Responses

PLoS Pathogens

Volumn 11, Issue 7, 2015, Pages

  Ansari, Mairaj Ahmed ^a   Dutta, Sujoy ^a   Veettil, Mohanan Valiya ^a   Dutta, Dipanjan ^a   Iqbal, Jawed ^a   Kumar, Binod ^a   Roy, Arunava ^a   Chikoti, Leela ^a   Singh, Vivek Vikram ^a   Chandran, Bala ^a  

^a ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CASPASE; CYTOKINE; E1A ASSOCIATED P300 PROTEIN; GAMMA INTERFERON INDUCIBLE PROTEIN 16; HISTONE ACETYLTRANSFERASE; INFLAMMASOME; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PROCASPASE 1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; IFI16 PROTEIN, HUMAN; NUCLEAR PROTEIN; PHOSPHOPROTEIN;

ACETYLATION; ARTICLE; B LYMPHOCYTE; BRDU ASSAY; CELL LYSATE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOKINE RESPONSE; CYTOTOXICITY ASSAY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPSTEIN BARR VIRUS INFECTION; FLOW CYTOMETRY; GENE EXPRESSION; HERPES VIRUS INFECTION; HERPESVIRIDAE; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 8; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOPRECIPITATION; INNATE IMMUNITY; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; VIRAL GENETICS; VIRUS GENOME; VIRUS REPLICATION; WESTERN BLOTTING; BIOSYNTHESIS; CELL LINE; CELL NUCLEUS; CYTOPLASM; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; HERPES SIMPLEX VIRUS 1; IMMUNOLOGY; METABOLISM; POLYMERASE CHAIN REACTION; PROTEIN TRANSPORT;

EUKARYOTA; HERPESVIRIDAE; HUMAN HERPESVIRUS 1; HUMAN HERPESVIRUS 4; HUMAN HERPESVIRUS 8; VACCINIA VIRUS;

ACETYLATION; BLOTTING, WESTERN; CELL LINE; CELL NUCLEUS; CHROMATIN IMMUNOPRECIPITATION; CYTOPLASM; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 1, HUMAN; HUMANS; IMMUNITY, INNATE; IMMUNOPRECIPITATION; INFLAMMASOMES; INTERFERON-BETA; MICROSCOPY, FLUORESCENCE; NUCLEAR PROTEINS; PHOSPHOPROTEINS; POLYMERASE CHAIN REACTION; PROTEIN TRANSPORT; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 84938805575     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005019     Document Type: Article

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