IFI16 Restricts HSV-1 Replication by Accumulating on the HSV-1 Genome, Repressing HSV-1 Gene Expression, and Directly or Indirectly Modulating Histone Modifications

PLoS Pathogens

Volumn 10, Issue 11, 2014, Pages

  Johnson, Karen E ^a   Bottero, Virginie ^a   Flaherty, Stephanie ^a   Dutta, Sujoy ^a   Singh, Vivek Vikram ^a   Chandran, Bala ^a  

^a ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BETA INTERFERON; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE FACTOR 16; INFLAMMASOME; INTERFERON REGULATORY FACTOR 3; LENTIVIRUS VECTOR; OCTAMER TRANSCRIPTION FACTOR 1; RNA POLYMERASE II; SMALL INTERFERING RNA; TATA BINDING PROTEIN; UNCLASSIFIED DRUG; HISTONE; IFI16 PROTEIN, HUMAN; NUCLEAR PROTEIN; PHOSPHOPROTEIN; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HERPES SIMPLEX VIRUS 1; HISTONE MODIFICATION; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; IMMUNOFLUORESCENCE TEST; MICROSCOPY; NONHUMAN; PROTEIN DEPLETION; REAL TIME POLYMERASE CHAIN REACTION; VIRUS GENOME; VIRUS REPLICATION; WESTERN BLOTTING; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; METABOLISM; PHYSIOLOGY; PROTEIN PROCESSING; TUMOR CELL LINE;

HUMAN HERPESVIRUS 1;

CELL LINE, TUMOR; GENE EXPRESSION REGULATION, VIRAL; GENOME, VIRAL; HEK293 CELLS; HERPESVIRUS 1, HUMAN; HISTONES; HUMANS; NUCLEAR PROTEINS; PHOSPHOPROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84912108081     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004503     Document Type: Article

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