Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia

Haematologica

Volumn 100, Issue 10, 2015, Pages 1301-1310

  Vicente, Carmen ^a,b   Schwab, Claire ^c   Broux, Michaël ^a,b   Geerdens, Ellen ^a,b   Degryse, Sandrine ^a,b   Demeyer, Sofie ^a,b   Lahortiga, Idoya ^a,b   Elliott, Alannah ^c   Chilton, Lucy ^c   La Starza, Roberta ^d   Mecucci, Cristina ^d   Vandenberghe, Peter ^a   Goulden, Nicholas ^e   Vora, Ajay ^f   Moorman, Anthony V ^c   Soulier, Jean ^g   Harrison, Christine J ^c   Clappier, Emmanuelle ^g   Cools, Jan ^a,b  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

^d UNIVERSITY OF PERUGIA   (Italy)

^e GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^f SHEFFIELD CHILDREN S HOSPITAL   (United Kingdom)

^g Institut Universitaire d'Hématologie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD135 ANTIGEN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; GENOMIC DNA; INTERLEUKIN 7; JANUS KINASE; JANUS KINASE 1; JANUS KINASE 3; NOTCH1 RECEPTOR; TRANSCRIPTION FACTOR CTCF; INTERLEUKIN 7 RECEPTOR;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ANIMAL CELL; ARTICLE; CHILD; COPY NUMBER VARIATION; CYTOGENETICS; EPIGENETICS; FEMALE; GENE FREQUENCY; GENETIC ANALYSIS; GENOMIC IN SITU HYBRIDIZATION; HUMAN; IMMUNOPHENOTYPING; INFANT; MAJOR CLINICAL STUDY; MALE; MUTATION; NONHUMAN; SCHOOL CHILD; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; T CELL LEUKEMIA; WESTERN BLOTTING; CLONAL EVOLUTION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION STUDY; GENETIC EPIGENESIS; GENETIC VARIATION; GENETICS; HIGH THROUGHPUT SEQUENCING; METABOLISM; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROGNOSIS; REPRODUCIBILITY; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; CHILD; CLONAL EVOLUTION; DNA COPY NUMBER VARIATIONS; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, LEUKEMIC; GENETIC ASSOCIATION STUDIES; GENETIC VARIATION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; JANUS KINASES; MALE; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROGNOSIS; RECEPTORS, INTERLEUKIN-7; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION;

EID: 84938756599     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2015.130179     Document Type: Article

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