Long noncoding RNA NEAT1 promotes glioma pathogenesis by regulating miR-449b-5p/c-Met axis

Tumor Biology

Volumn 37, Issue 1, 2016, Pages 673-683

  Zhen, Li ^a   Yun hui, Liu ^a   Hong yu, Diao ^a   Jun, Ma ^a   Yi long, Yao ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

c Met; Glioma; Long noncoding RNA; miR 449b 3p; NEAT1

Indexed keywords

LONG UNTRANSLATED RNA; MICRORNA; MICRORNA 449B 5P; NUCLEAR ENRICHED ABUNDANT TRANSCRIPT 1; SCATTER FACTOR RECEPTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; MIRN449 MICRORNA, HUMAN; NEAT1 LONG NON-CODING RNA, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN SURGERY; CANCER GROWTH; CANCER INHIBITION; CARCINOGENESIS; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE FUNCTION; GENE REPRESSION; GENE SILENCING; GLIOMA; GLIOMA CELL LINE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR INVASION; TUMOR XENOGRAFT; UPREGULATION; ANIMAL; APOPTOSIS; BINDING SITE; BIOLOGICAL MODEL; CELL MOTION; CELL TRANSFORMATION; DISEASE MODEL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; NUCLEOTIDE SEQUENCE; RNA INTERFERENCE; TUMOR CELL LINE; XENOGRAFT;

ANIMALS; APOPTOSIS; BASE SEQUENCE; BINDING SITES; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; GLIOMA; HETEROGRAFTS; HUMANS; MICE; MICRORNAS; MODELS, BIOLOGICAL; PROTO-ONCOGENE PROTEINS C-MET; RNA INTERFERENCE; RNA, LONG NONCODING; UP-REGULATION;

EID: 84938723417     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-015-3843-y     Document Type: Article

References (35)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011;61:69–90.
2. Siegel R, Ma J, Zou Z, Jemal A. Cancer statistics, 2014. CA Cancer J Clin. 2014;64:9–29.
3. Hegi ME, Janzer RC, Lambiv WL, Gorlia T, Kouwenhoven MC, Hartmann C, et al. European Organisation for R, Treatment of Cancer Brain T, Radiation Oncology G, National Cancer Institute of Canada Clinical Trials G: Presence of an oligodendroglioma-like component in newly diagnosed glioblastoma identifies a pathogenetically heterogeneous subgroup and lacks prognostic value: Central pathology review of the eortc_26981/ncic_ce.3 trial. Acta Neuropathol. 2012;123:841–52.
4. Wang Y, Jiang T. Understanding high grade glioma: Molecular mechanism, therapy and comprehensive management. Cancer Lett. 2013;331:139–46.
5. Ohkawa Y, Momota H, Kato A, Hashimoto N, Tsuda Y, Kotani N, Honke K, Suzumura A, Furukawa K, Ohmi Y, Natsume A, Wakabayashi T, Furukawa K: Ganglioside gd3 enhances invasiveness of gliomas by forming a complex with platelet-derived growth factor receptor alpha and yes. The Journal of biological chemistry 2015.
6. Lin JJ, Zhao TZ, Cai WK, Yang YX, Sun C, Zhang Z, Xu YQ, Chang T, Li ZY: Inhibition of histamine receptor 3 suppresses glioblastoma tumor growth, invasion, and epithelial-to-mesenchymal transition. Oncotarget 2015.
7. Maruyama R, Suzuki H. Long noncoding rna involvement in cancer. BMB Rep. 2012;45:604–11.
8. Esteller M. Non-coding rnas in human disease. Nat Rev Genet. 2011;12:861–74.
9. Mercer TR, Dinger ME, Mattick JS. Long non-coding rnas: Insights into functions. Nat Rev Genet. 2009;10:155–9.
10. Han L, Zhang K, Shi Z, Zhang J, Zhu J, Zhu S, Zhang A, Jia Z, Wang G, Yu S, Pu P, Dong L, Kang C: Lncrna pro fi le of glioblastoma reveals the potential role of lncrnas in contributing to glioblastoma pathogenesis. International journal of oncology 2012;40:2004–2012.
11. Zhang X, Zhou Y, Mehta KR, Danila DC, Scolavino S, Johnson SR, et al. A pituitary-derived meg3 isoform functions as a growth suppressor in tumor cells. J Clin Endocrinol Metab. 2003;88:5119–26.
12. Zhang JX, Han L, Bao ZS, Wang YY, Chen LY, Yan W, et al. Chinese Glioma Cooperative G: Hotair, a cell cycle-associated long noncoding rna and a strong predictor of survival, is preferentially expressed in classical and mesenchymal glioma. Neuro-Oncology. 2013;15:1595–603.
13. Choudhry H, Schodel J, Oikonomopoulos S, Camps C, Grampp S, Harris AL, et al. Extensive regulation of the non-coding transcriptome by hypoxia: Role of hif in releasing paused rnapol2. EMBO Rep. 2014;15:70–6.
14. Guru SC, Agarwal SK, Manickam P, Olufemi SE, Crabtree JS, Weisemann JM, et al. A transcript map for the 2.8-mb region containing the multiple endocrine neoplasia type 1 locus. Genome Res. 1997;7:725–35.
15. Kim YS, Hwan JD, Bae S, Bae DH, Shick WA. Identification of differentially expressed genes using an annealing control primer system in stage iii serous ovarian carcinoma. BMC Cancer. 2010;10:576.
16. Zeng C, Xu Y, Xu L, Yu X, Cheng J, Yang L, et al. Inhibition of long non-coding rna neat1 impairs myeloid differentiation in acute promyelocytic leukemia cells. BMC Cancer. 2014;14:693.
17. Salmena L, Poliseno L, Tay Y, Kats L, Pandolfi PP. A cerna hypothesis: The rosetta stone of a hidden rna language? Cell. 2011;146:353–8.
18. Tay Y, Kats L, Salmena L, Weiss D, Tan SM, Ala U, et al. Coding-independent regulation of the tumor suppressor pten by competing endogenous mrnas. Cell. 2011;147:344–57.
19. Wang Y, Xu Z, Jiang J, Xu C, Kang J, Xiao L, et al. Endogenous mirna sponge lincrna-ror regulates oct4, nanog, and sox2 in human embryonic stem cell self-renewal. Dev Cell. 2013;25:69–80.
20. Karreth FA, Tay Y, Perna D, Ala U, Tan SM, Rust AG, et al. In vivo identification of tumor- suppressive pten cernas in an oncogenic braf-induced mouse model of melanoma. Cell. 2011;147:382–95.
21. Sumazin P, Yang X, Chiu HS, Chung WJ, Iyer A, Llobet-Navas D, et al. An extensive microrna-mediated network of rna-rna interactions regulates established oncogenic pathways in glioblastoma. Cell. 2011;147:370–81.
22. Wang Y, Wang Y, Li J, Zhang Y, Yin H, Han B: Crnde, a long-noncoding rna, promotes glioma cell growth and invasion through mtor signaling. Cancer letters 2015.
23. Wang P, Liu YH, Yao YL, Li Z, Li ZQ, Ma J, et al. Long non-coding rna casc2 suppresses malignancy in human gliomas by mir-21. Cell Signal. 2015;27:275–82.
24. Wan HY, Guo LM, Liu T, Liu M, Li X, Tang H. Regulation of the transcription factor nf-kappab1 by microrna-9 in human gastric adenocarcinoma. Mol Cancer. 2010;9:16.
25. Tani H, Torimura M, Akimitsu N. The rna degradation pathway regulates the function of gas5 a non-coding rna in mammalian cells. PLoS One. 2013;8, e55684.
26. Kino T, Hurt DE, Ichijo T, Nader N, Chrousos GP: Noncoding rna gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor. Science signaling 2010;3:ra8.
27. Ma MZ, Chu BF, Zhang Y, Weng MZ, Qin YY, Gong W, et al. Long non-coding rna ccat1 promotes gallbladder cancer development via negative modulation of mirna-218-5p. Cell Death Dis. 2015;6, e1583.
28. Hirose T, Virnicchi G, Tanigawa A, Naganuma T, Li R, Kimura H, et al. Neat1 long noncoding rna regulates transcription via protein sequestration within subnuclear bodies. Mol Biol Cell. 2014;25:169–83.
29. Choudhry H, Albukhari A, Morotti M, Hider S, Moralli D, Smythies J, Schodel J, Green CM, Camps C, Buffa F, Ratcliffe P, Ragoussis J, Harris AL, Mole DR: Tumor hypoxia induces nuclear paraspeckle formation through hif-2alpha dependent transcriptional activation of neat1 leading to cancer cell survival. Oncogene 2014.
30. Chakravarty D, Sboner A, Nair SS, Giannopoulou E, Li R, Hennig S, et al. The oestrogen receptor alpha-regulated lncrna neat1 is a critical modulator of prostate cancer. Nat Commun. 2014;5:5383.
31. Zhong X, Coukos G, Zhang L. Mirnas in human cancer. Methods Mol Biol. 2012;822:295–306.
32. Gabriely G, Yi M, Narayan RS, Niers JM, Wurdinger T, Imitola J, et al. Human glioma growth is controlled by microrna-10b. Cancer Res. 2011;71:3563–72.
33. Suh SS, Yoo JY, Nuovo GJ, Jeon YJ, Kim S, Lee TJ, et al. Micrornas/tp53 feedback circuitry in glioblastoma multiforme. Proc Natl Acad Sci U S A. 2012;109:5316–21.
34. Jeon HS, Lee SY, Lee EJ, Yun SC, Cha EJ, Choi E, et al. Combining microrna-449a/b with a hdac inhibitor has a synergistic effect on growth arrest in lung cancer. Lung Cancer. 2012;76:171–6.
35. Ren XS, Yin MH, Zhang X, Wang Z, Feng SP, Wang GX, et al. Tumor-suppressive microrna-449a induces growth arrest and senescence by targeting e2f3 in human lung cancer cells. Cancer Lett. 2014;344:195–203.