Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification

Development (Cambridge)

Volumn 142, Issue 15, 2015, Pages 2586-2597

  O’Shaughnessy Kirwan, Aoife ^a   Signolet, Jason ^a   Costello, Ita ^b,c   Gharbi, Sarah ^a   Hendrich, Brian ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Blastocyst; CHD4; Chromatin remodelling; Lineage commitment; Transcription; Trophectoderm

Indexed keywords

CELL PROTEIN; CHROMODOMAIN HELICASE DNA BINDING PROTEIN 4; DNA BINDING PROTEIN; HISTONE H3; UNCLASSIFIED DRUG; DNA HELICASE; MI-2BETA PROTEIN, MOUSE; PRIMER DNA;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLASTOCYST; CELL CYCLE PROGRESSION; CELL FATE; CELL LINEAGE; CELL MUTANT; CELL VIABILITY; CONTROLLED STUDY; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; EX VIVO STUDY; FEMALE; GENE EXPRESSION; HETEROZYGOTE; HISTONE PHOSPHORYLATION; HOUSEKEEPING GENE; MAMMAL CELL; MOUSE; NIDATION; NONHUMAN; NULL CELL; PLURIPOTENT STEM CELL; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; PROTEIN FUNCTION; SOMATIC CELL; TROPHECTODERM; WILD TYPE; ZONA PELLUCIDA; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; CHROMATIN ASSEMBLY AND DISASSEMBLY; CROSS BREEDING; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MULTIPLEX POLYMERASE CHAIN REACTION; PHYSIOLOGY; SINGLE CELL ANALYSIS; TUNEL ASSAY;

MAMMALIA; METAZOA;

ANIMALS; BLASTOCYST; CELL DIFFERENTIATION; CELL LINEAGE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CROSSES, GENETIC; DNA HELICASES; DNA PRIMERS; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IN SITU NICK-END LABELING; MICE; MICE, INBRED C57BL; MULTIPLEX POLYMERASE CHAIN REACTION; SINGLE-CELL ANALYSIS;

EID: 84938634462     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.125450     Document Type: Article

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