Mi2b-mediated silencing of the fetal g-globin gene in adult erythroid cells

Blood

Volumn 121, Issue 17, 2013, Pages 3493-3501

  Amaya, Maria ^a,b   Desai, Megha ^a,b   Gnanapragasam, Merlin Nithya ^a,b   Wang, Shou Zhen ^a   Zhu, Sheng Zu ^a   Williams, David C ^a,b   Ginder, Gordon D ^c,d  

^a Massey Cancer Center   (Australia)

^b Department of Microbiology and Immunology ^*  (Australia)

^c Virginia Commonweath University   (Australia)

^d VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CHROMATIN ORGANIZATION MODIFIER 4; HELICASE; HEMOGLOBIN F; TRANSCRIPTION FACTOR GATA 1; UNCLASSIFIED DRUG; AUTOANTIGEN; BCL11A PROTEIN, HUMAN; CARRIER PROTEIN; CHD4 PROTEIN, HUMAN; ERYTHROID KRUPPEL LIKE FACTOR; ERYTHROID KRUPPEL-LIKE FACTOR; HEMOGLOBIN GAMMA CHAIN; HISTONE DEACETYLASE; KRUPPEL LIKE FACTOR; NUCLEAR PROTEIN; SMALL INTERFERING RNA;

ARTICLE; CELL DIFFERENTIATION; ERYTHROID CELL; GAMMA GLOBIN GENE; GENE EXPRESSION; GENE SILENCING; GENE SWITCHING; GLOBIN GENE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; REGULATORY MECHANISM; ADULT; ANIMAL; CELL CULTURE; CHROMATIN IMMUNOPRECIPITATION; CYTOLOGY; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETICS; HEMATOPOIETIC STEM CELL; METABOLISM; MOUSE; TRANSGENIC MOUSE;

ADULT; ANIMALS; AUTOANTIGENS; CARRIER PROTEINS; CELL DIFFERENTIATION; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; ERYTHROID CELLS; FETAL HEMOGLOBIN; GAMMA-GLOBINS; GENE EXPRESSION REGULATION; GENE SILENCING; HEMATOPOIETIC STEM CELLS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MI-2 NUCLEOSOME REMODELING AND DEACETYLASE COMPLEX; MICE; MICE, TRANSGENIC; NUCLEAR PROTEINS; RNA, SMALL INTERFERING;

MLCS; MLOWN;

EID: 84876258481     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-11-466227     Document Type: Article

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