Septic cardiomyopathy in rat LPS-induced endotoxemia: relative contribution of cellular diastolic Ca2+ removal pathways, myofibrillar biomechanics properties and action of the cardiotonic drug levosimendan

Basic Research in Cardiology

Volumn 110, Issue 5, 2015, Pages

  Wagner, S ^a,b   Schurmann S ^a   Hein, S ^c   Schuttler J ^b   Friedrich, O ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^c UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

Calcium; Cardiomyopathy; Levosimendan; Motility assay; Sepsis

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); LEVOSIMENDAN; MYOSIN ADENOSINE TRIPHOSPHATASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SODIUM CALCIUM EXCHANGE PROTEIN; CALCIUM; CARDIOTONIC AGENT; HYDRAZONE DERIVATIVE; LIPOPOLYSACCHARIDE; PYRIDAZINE DERIVATIVE; SIMENDAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM SIGNALING; CALCIUM TRANSPORT; CARDIOMYOPATHY; CELL MOTILITY; CONTROLLED STUDY; DRUG MECHANISM; ENDOTOXEMIA; FORCE TRANSDUCER; HEART CONTRACTION; HEART HEMODYNAMICS; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PROTEIN INTERACTION; RAT; SEPTIC CARDIOMYOPATHY; TRANSPORT KINETICS; ANIMAL; CARDIOMYOPATHIES; CHEMICALLY INDUCED; COMPLICATION; CONFOCAL MICROSCOPY; DRUG EFFECTS; HEMODYNAMICS; HOMEOSTASIS; METABOLISM; MUSCLE FIBRIL; PHYSIOLOGY; SARCOLEMMA; WISTAR RAT;

ANIMALS; CALCIUM; CARDIOMYOPATHIES; CARDIOTONIC AGENTS; ENDOTOXEMIA; HEMODYNAMICS; HOMEOSTASIS; HYDRAZONES; LIPOPOLYSACCHARIDES; MALE; MICROSCOPY, CONFOCAL; MYOFIBRILS; PYRIDAZINES; RATS; RATS, WISTAR; SARCOLEMMA;

EID: 84938598705     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-015-0507-4     Document Type: Article

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