The role of endothelin-1 in circulatory changes during hypodynamic sepsis in the rat

Shock

Volumn 10, Issue 2, 1998, Pages 123-128

  Szalay, László ^a   Kaszaki, József ^a   Nagy, Sándor ^a   Boros, Mihály ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

BQ 610; CYS(11) CYS(15) ENDOTHELIN 1 (11 21); CYS(11)-CYS(15)-ENDOTHELIN-1 (11-21); ENDOTHELIN; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ENDOTHELIN RECEPTOR; ETR P1 F1 ANTISENSE PEPTIDE; ETR-P1-F1 ANTISENSE PEPTIDE; OLIGOPEPTIDE; PEPTIDE; PEPTIDE FRAGMENT;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BLOOD PRESSURE; CECUM; DRUG ANTAGONISM; DRUG EFFECT; HEART OUTPUT; HEMODYNAMICS; MALE; MOLECULAR GENETICS; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; SEPSIS; VASCULAR RESISTANCE; WISTAR RAT;

AMINO ACID SEQUENCE; ANIMALS; BLOOD PRESSURE; CARDIAC OUTPUT; CECUM; ENDOTHELIN-1; ENDOTHELINS; HEMODYNAMIC PROCESSES; MALE; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PEPTIDES; RATS; RATS, WISTAR; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN; SEPSIS; VASCULAR RESISTANCE;

EID: 0032134918     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-199808000-00007     Document Type: Article

References (32)

1. Hickey KA, Rubanyi GM, Paul RJ, Highsmith RF: Characterization of a coronary vasoconstrictor produced by cultured endothelial cells. Am J Physiol 248:C550-C556, 1985.
2. Yanagisava M, Kurihara H, Kimura S, et al: A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332:411-415, 1988.
3. Inoue A, Yanagisawa M, Kimura S, et al: The human endothelin family: Three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc Natl Acad Sci USA 86:2863-2867, 1989.
4. Arai H, Hori S, Aramori I, Ohkubo H, Nakanishi S: Cloning and expression of a cDNA encoding an endothelin receptor. Nature 348:730-732, 1990.
5. Sakurai T, Yanagisawa M, Takuwa Y, et al: Cloning of a cDNA encoding a non-isopeptide selective subtype of the endothelin receptor. Nature 348:732-735, 1990.
6. Karne S, Jayawickreme CK, Lerner MR: Cloning and characterization of an endothelin-3 specific receptor (ET-C receptor) from Xenopus laevis dermal melanophores. J Biol Chem 268:19126-19133, 1993.
7. Clozel M, Gray GA, Breu V, Löfflet BM, Osterwalder R: The endothelin ET-B receptor mediates both vasodilation and vasoconstriction in vivo. Biochem Biophys Res Commun 186:867-873, 1992.
8. Sumner MJ, Cannon TR, Mundin, JW, White DG, Watts DG: Endothelin ETA and ETB receptors mediate vascular smooth muscle contraction. Br J Pharmacol 107:858-860, 1992.
9. Bird JE, Waldron TL: Incomplete inhibition of endothelin-1 pressor effects by an endothelin ETA receptor antagonist. Eur J Pharmacol 240: 295-298, 1993.
10. Shetty SS, Okada T, Webb RL, DelGrande D, Lappe RW: Functionally distinct endothelin-B receptors in vascular endothelium and smooth muscle. Biochem Biophys Res Commun 191:459-467, 1993.
11. Nakamura T, Kasai K, Sekiguchi Y, et al: Elevation of plasma endothelin concentrations during endotoxin shock in dogs. Eur J Pharmacol 205: 277-282, 1991.
12. Vemulapalli S, Chiu PJ, Rivelli M, Foster CJ, Sybertz EJ: Modulation of circulating endothelin levels in hypertension and endotoxemia in rats. J Cardiovasc Pharmacol 18:895-903, 1991.
13. Weitzberg E, Lundberg JM, Rudehill A: Elevated plasma levels of endothelin in patients with sepsis syndrome. Circ Shock 33:222-227, 1991.
14. Kaddoura S, Curzen NP, Evans TW, Firth JD, Poole-Wilson PA: Tissue expression of endothelin mRNA in endotoxemia. Biochem Biophys Res Commun 218:641-647, 1996.
15. Baranyi L, Campbell W, Ohshima K, Fujimoto S, Boros M, Okada H: The antisense homology box: A new motif within proteins that encodes biologically active peptides. Nat Med 1:894-901, 1995.
16. Ishikawa K, Fukami T, Nagase T, et al: Endothelin antagonistic peptide derivatives with high selectivity for ET-A receptors. Peptides 685-686, 1992.
17. Thompson A, Valeri CR, Lieberthal W: Endothelin receptor A blockade alters hemodynamic response to nitric oxide inhibition in rats. Am J Physiol 269:H743-H748, 1995
18. Urade Y, Fujitani Y, Oda K, et al: An endothelin B receptor-selective antagonist: IRL-1038, [Cys11-Cys15]-endothelin-1(11-21). FEBS Lett 311:12-16, 1992.
19. Boros M, Massberg S, Baranyi L, Okada H, Messmer K: Endothelin-1 induces leukocyte adhesion in submucosal venules of the rat small intestine: The effects of selective receptor antagonists. Gastroenterology 114:103-114, 1998.
20. Siegel JH, Greenspan M, Del Guerico LRM: Abnormal vascular tone, defective oxygen transport and myocardial failure in human septic shock. Ann Surg 165:504-517, 1967.
21. Mulder MF, van Lambalgen AA, van den Bos GC, Thijs LG: The fall of cardiac output in endotoxemic rats cannot explain all changes in organ blood flow: A comparison between endotoxin and low venous return shock. Shock 5:135-140, 1996.
22. Haynes WG, Ferro CJ, O'Kane KP, Sommerville D, Lomax CC, Webb DJ: Systemic endothelin receptor blockade decreases peripheral vascular resistance and blood pressure in humans. Circulation 93:1860-1870, 1996.
23. Rubanyi GM, Polokoff MA: Endothelins: Molecular biology, biochemistry, pharmacology, physiology and pathophysiology. Pharmacol Rev 46: 325-415, 1994.
24. Clozel M, Breu V: The role of ETB receptors in normotensive and hypertensive rats as revealed by the non-peptide selective ETB receptor antagonist Ro 46-8443. FEBS Lett 383:42-45, 1996.
25. Lamy M, Deby-Dupont G: Is sepsis a mediator-inhibitor mismatch? Int Care Med 21:S250-S257, 1995.
26. Marsden PA, Brenner BM: Transcriptional regulation of the endothelin-1 gene by TNF-α. Am J Physiol 262:C854-C861, 1992.
27. Sugiura M, Inagami T, Kon V: Endotoxin stimulates endothelin-release in vivo and in vitro as determined by radioimmunoassay. Biochem Biophys Res Commun 161:1220, 1989.
28. Lundblad R, Giercksky KE: Endothelin concentrations in experimental sepsis: Profiles of big endothelin and endothelin 1-21 in lethal peritonitis in rats. Eur J Surg 161:9-16, 1995.
29. Ruetten H, Thiemermann C, Vane JR: Effects of the endothelin receptor antagonist, SB 209670, on circulatory failure and organ injury in endotoxic shock in the anaesthetized rat. Br J Pharmacol 118:198-204, 1996.
30. Gardiner SM, Kemp PA, March JE, Bennett T: Temporal differences between the involvement of angiotensin II and endothelin in the cardiovascular responses to endotoxaemia in conscious rats. Br J Pharmacol 119:1619-1627, 1996.
31. Allcock GH, Warner TD, Vane JR: Roles of endothelin receptors in the regional and systemic vascular responses to ET-1 in the anaesthetized ganglion-blocked rat: Use of selective antagonists. Br J Pharmacol 116: 2482-2486, 1995.
32. Davenport AP, O'Reilly G, Kuc RE: Endothelin ETA and ETB mRNA and receptors expressed by smooth muscle in the human vasculature: Majority of the ETA sub-type. Br J Pharmacol 114:1110-1116, 1995.