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Volumn 31, Issue 6, 2013, Pages e115-e124

The effect of SN-6, a novel sodium-calcium exchange inhibitor, on contractility and calcium handling in isolated failing rat ventricular myocytes

Author keywords

Benzyloxyphenyl; Calcium handling; Contractility; Heart failure; Myofilament sensitivity; NCX; Rat cardiomyocyte; SN 6; Sodium calcium exchanger

Indexed keywords

CAFFEINE; CALCIUM ION; SN 6; TIMONACIC DERIVATIVE; UNCLASSIFIED DRUG;

EID: 84888318454     PISSN: 17555914     EISSN: 17555922     Source Type: Journal    
DOI: 10.1111/1755-5922.12045     Document Type: Article
Times cited : (12)

References (46)
  • 1
    • 0032801648 scopus 로고    scopus 로고
    • Sodium/calcium exchange: its physiological implications
    • Blaustein MP, Lederer WJ. Sodium/calcium exchange: its physiological implications. Physiol Rev 1999;79:763.
    • (1999) Physiol Rev , vol.79 , pp. 763
    • Blaustein, M.P.1    Lederer, W.J.2
  • 2
    • 33845665302 scopus 로고    scopus 로고
    • Regulation of Ca2+ and Na+ in normal and failing cardiac myocytes
    • Bers DM, Despa S, Bossuyt J. Regulation of Ca2+ and Na+ in normal and failing cardiac myocytes. Ann N Y Acad Sci 2006;1080:165-177.
    • (2006) Ann N Y Acad Sci , vol.1080 , pp. 165-177
    • Bers, D.M.1    Despa, S.2    Bossuyt, J.3
  • 3
    • 0033538344 scopus 로고    scopus 로고
    • Ca2+ handling and sarcoplasmic reticulum Ca2+ content in isolated failing and nonfailing human myocardium
    • Pieske B, Maier LS, Bers DM, Hasenfuss G. Ca2+ handling and sarcoplasmic reticulum Ca2+ content in isolated failing and nonfailing human myocardium. Circ Res 1999;85:38-46.
    • (1999) Circ Res , vol.85 , pp. 38-46
    • Pieske, B.1    Maier, L.S.2    Bers, D.M.3    Hasenfuss, G.4
  • 4
    • 0033583244 scopus 로고    scopus 로고
    • Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, I: experimental studies
    • O'Rourke B, Kass DA, Tomaselli GF, Kaab S, Tunin R, Marban E. Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, I: experimental studies. Circ Res 1999;84:562-570.
    • (1999) Circ Res , vol.84 , pp. 562-570
    • O'Rourke, B.1    Kass, D.A.2    Tomaselli, G.F.3    Kaab, S.4    Tunin, R.5    Marban, E.6
  • 5
    • 58749107732 scopus 로고    scopus 로고
    • Cardiac Contractility Modulation Electrical Signals Normalize Activity, Expression, and Phosphorylation of the Na+-Ca2+ Exchanger in Heart Failure
    • Gupta RC, Mishra S, Wang M, et al. Cardiac Contractility Modulation Electrical Signals Normalize Activity, Expression, and Phosphorylation of the Na+-Ca2+ Exchanger in Heart Failure. J Card Fail 2009;15:48-56.
    • (2009) J Card Fail , vol.15 , pp. 48-56
    • Gupta, R.C.1    Mishra, S.2    Wang, M.3
  • 6
    • 7444246923 scopus 로고    scopus 로고
    • Na+/Ca2+ exchanger overexpression impairs frequency- and ouabain-dependent cell shortening in adult rat cardiomyocytes
    • Bolck B, Munch G, Mackenstein P, et al. Na+/Ca2+ exchanger overexpression impairs frequency- and ouabain-dependent cell shortening in adult rat cardiomyocytes. Am J Physiol Heart Circ Physiol 2004;287:H1435-H1445.
    • (2004) Am J Physiol Heart Circ Physiol , vol.287
    • Bolck, B.1    Munch, G.2    Mackenstein, P.3
  • 7
    • 0034730809 scopus 로고    scopus 로고
    • Impaired Contractile Performance of Cultured Rabbit Ventricular Myocytes After Adenoviral Gene Transfer of Na+-Ca2+ Exchanger
    • Schillinger W, Janssen PML, Emami S, et al. Impaired Contractile Performance of Cultured Rabbit Ventricular Myocytes After Adenoviral Gene Transfer of Na+-Ca2+ Exchanger. Circ Res 2000;87:581-587.
    • (2000) Circ Res , vol.87 , pp. 581-587
    • Schillinger, W.1    Janssen, P.M.L.2    Emami, S.3
  • 8
    • 0036545437 scopus 로고    scopus 로고
    • Effects of Na()/Ca(2)-exchanger overexpression on excitation-contraction coupling in adult rabbit ventricular myocytes
    • Ranu HK. Effects of Na()/Ca(2)-exchanger overexpression on excitation-contraction coupling in adult rabbit ventricular myocytes. J Mol Cell Cardiol 2002;34:389.
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 389
    • Ranu, H.K.1
  • 9
    • 41149087204 scopus 로고    scopus 로고
    • Altered Na+/Ca2+-exchanger activity due to downregulation of Na+/K+-ATPase alpha2-isoform in heart failure
    • Swift F, Birkeland JA, Tovsrud N, et al. Altered Na+/Ca2+-exchanger activity due to downregulation of Na+/K+-ATPase alpha2-isoform in heart failure. Cardiovasc Res 2008;78:71-78.
    • (2008) Cardiovasc Res , vol.78 , pp. 71-78
    • Swift, F.1    Birkeland, J.A.2    Tovsrud, N.3
  • 10
    • 61949206575 scopus 로고    scopus 로고
    • Regulation of intracellular and mitochondrial sodium in health and disease
    • Murphy E, Eisner DA. Regulation of intracellular and mitochondrial sodium in health and disease. Circ Res 2009;104:292-303.
    • (2009) Circ Res , vol.104 , pp. 292-303
    • Murphy, E.1    Eisner, D.A.2
  • 12
    • 3042761614 scopus 로고    scopus 로고
    • The potential of Na+/Ca2+ exchange blockers in the treatment of cardiac disease
    • Hobai IA, O'Rourke B. The potential of Na+/Ca2+ exchange blockers in the treatment of cardiac disease. Expert Opin Investig Drugs 2004;13:653-664.
    • (2004) Expert Opin Investig Drugs , vol.13 , pp. 653-664
    • Hobai, I.A.1    O'Rourke, B.2
  • 13
    • 33745068551 scopus 로고    scopus 로고
    • Sodium-calcium exchange inhibitors: therapeutic potential in cardiovascular diseases
    • Iwamoto T. Sodium-calcium exchange inhibitors: therapeutic potential in cardiovascular diseases. Future Cardiol 2005;1:519-529.
    • (2005) Future Cardiol , vol.1 , pp. 519-529
    • Iwamoto, T.1
  • 14
    • 4043107664 scopus 로고    scopus 로고
    • Partial inhibition of sodium/calcium exchange restores cellular calcium handling in canine heart failure
    • Hobai IA, Maack C, O'Rourke B. Partial inhibition of sodium/calcium exchange restores cellular calcium handling in canine heart failure. Circ Res 2004;95:292.
    • (2004) Circ Res , vol.95 , pp. 292
    • Hobai, I.A.1    Maack, C.2    O'Rourke, B.3
  • 15
    • 0029788017 scopus 로고    scopus 로고
    • A novel isothiourea derivative selectively inhibits the reverse mode of Na+/Ca2+ exchange in cells expressing NCX1
    • Iwamoto T, Watano T, Shigekawa M. A novel isothiourea derivative selectively inhibits the reverse mode of Na+/Ca2+ exchange in cells expressing NCX1. J Biol Chem 1996;271:22391-22397.
    • (1996) J Biol Chem , vol.271 , pp. 22391-22397
    • Iwamoto, T.1    Watano, T.2    Shigekawa, M.3
  • 16
    • 0034724436 scopus 로고    scopus 로고
    • KB-R7943 block of Ca(2+) influx via Na(+)/Ca(2+) exchange does not alter twitches or glycoside inotropy but prevents Ca(2+) overload in rat ventricular myocytes
    • Satoh H, Ginsburg KS, Qing K, Terada H, Hayashi H, Bers DM. KB-R7943 block of Ca(2+) influx via Na(+)/Ca(2+) exchange does not alter twitches or glycoside inotropy but prevents Ca(2+) overload in rat ventricular myocytes. Circulation 2000;101:1441-1446.
    • (2000) Circulation , vol.101 , pp. 1441-1446
    • Satoh, H.1    Ginsburg, K.S.2    Qing, K.3    Terada, H.4    Hayashi, H.5    Bers, D.M.6
  • 17
    • 0346789109 scopus 로고    scopus 로고
    • Pharmacology of KB-R7943: a Na+-Ca2+ exchange inhibitor
    • Amran MS, Homma N, Hashimoto K. Pharmacology of KB-R7943: a Na+-Ca2+ exchange inhibitor. Cardiovasc Drug Rev 2003;21:255-276.
    • (2003) Cardiovasc Drug Rev , vol.21 , pp. 255-276
    • Amran, M.S.1    Homma, N.2    Hashimoto, K.3
  • 18
    • 35348916613 scopus 로고    scopus 로고
    • Effect of partial blockade of the Na+/Ca2+-exchanger on Ca2+ handling in isolated rat ventricular myocytes
    • Acsai K, Kun A, Farkas AS, et al. Effect of partial blockade of the Na+/Ca2+-exchanger on Ca2+ handling in isolated rat ventricular myocytes. Eur J Pharmacol 2007;576:1-6.
    • (2007) Eur J Pharmacol , vol.576 , pp. 1-6
    • Acsai, K.1    Kun, A.2    Farkas, A.S.3
  • 19
    • 44449087827 scopus 로고    scopus 로고
    • The Na+/Ca2+ exchange blocker SEA0400 fails to enhance cytosolic Ca2 transient and contractility in canine ventricular cardiomyocytes
    • Birinyi P, Tóth A, Jóna I, et al. The Na+/Ca2+ exchange blocker SEA0400 fails to enhance cytosolic Ca2 transient and contractility in canine ventricular cardiomyocytes. Cardiovasc Res 2008;78:476.
    • (2008) Cardiovasc Res , vol.78 , pp. 476
    • Birinyi, P.1    Tóth, A.2    Jóna, I.3
  • 20
    • 44949140716 scopus 로고    scopus 로고
    • Pharmacological inhibition of Na/Ca exchange results in increased cellular Ca2+ load attributable to the predominance of forward mode block
    • Ozdemir S, Bito V, Holemans P, et al. Pharmacological inhibition of Na/Ca exchange results in increased cellular Ca2+ load attributable to the predominance of forward mode block. Circ Res 2008;102:1398-1405.
    • (2008) Circ Res , vol.102 , pp. 1398-1405
    • Ozdemir, S.1    Bito, V.2    Holemans, P.3
  • 21
    • 45849114731 scopus 로고    scopus 로고
    • SEA0400 fails to alter the magnitude of intracellular Ca2 transients and contractions in Langendorff-perfused guinea pig heart
    • Szentandrássy N, Birinyi P, Szigeti G, et al. SEA0400 fails to alter the magnitude of intracellular Ca2 transients and contractions in Langendorff-perfused guinea pig heart. Naunyn-Schmiedeberg's Arch Pharmacol 2008;378:65.
    • (2008) Naunyn-Schmiedeberg's Arch Pharmacol , vol.378 , pp. 65
    • Szentandrássy, N.1    Birinyi, P.2    Szigeti, G.3
  • 22
    • 42949123383 scopus 로고    scopus 로고
    • Na(+)/Ca(2+) exchanger inhibition exerts a positive inotropic effect in the rat heart, but fails to influence the contractility of the rabbit heart
    • Farkas AS, Acsai K, Nagy N, et al. Na(+)/Ca(2+) exchanger inhibition exerts a positive inotropic effect in the rat heart, but fails to influence the contractility of the rabbit heart. Br J Pharmacol 2008;154:93-104.
    • (2008) Br J Pharmacol , vol.154 , pp. 93-104
    • Farkas, A.S.1    Acsai, K.2    Nagy, N.3
  • 23
    • 16644370582 scopus 로고    scopus 로고
    • Characterization of SN-6, a novel exchange inhibitor and its renal protective effect
    • Inoue Y, Ito K, Sakaue T, Iwamoto T, Kita S. Characterization of SN-6, a novel exchange inhibitor and its renal protective effect. Clin Calcium 2004;14:84-91.
    • (2004) Clin Calcium , vol.14 , pp. 84-91
    • Inoue, Y.1    Ito, K.2    Sakaue, T.3    Iwamoto, T.4    Kita, S.5
  • 24
    • 34648858691 scopus 로고    scopus 로고
    • Characterization of SN-6, a novel Na+/Ca2+ exchange inhibitor in guinea pig cardiac ventricular myocytes
    • Niu C, Watanabe Y, Ono K, et al. Characterization of SN-6, a novel Na+/Ca2+ exchange inhibitor in guinea pig cardiac ventricular myocytes. Eur J Pharmacol 2007;573:161.
    • (2007) Eur J Pharmacol , vol.573 , pp. 161
    • Niu, C.1    Watanabe, Y.2    Ono, K.3
  • 25
    • 3042579803 scopus 로고    scopus 로고
    • The exchanger inhibitory peptide region-dependent inhibition of Na+/Ca2+ exchange by SN-6 [2-[4-(4-Nitrobenzyloxy)benzyl]thiazolidine-4-carboxylic acid ethyl ester], a novel benzyloxyphenyl derivative
    • Iwamoto T, Inoue Y, Ito K, Sakaue T, Kita S, Katsuragi T. The exchanger inhibitory peptide region-dependent inhibition of Na+/Ca2+ exchange by SN-6 [2-[4-(4-Nitrobenzyloxy)benzyl]thiazolidine-4-carboxylic acid ethyl ester], a novel benzyloxyphenyl derivative. Mol Pharmacol 2004;66:45-55.
    • (2004) Mol Pharmacol , vol.66 , pp. 45-55
    • Iwamoto, T.1    Inoue, Y.2    Ito, K.3    Sakaue, T.4    Kita, S.5    Katsuragi, T.6
  • 26
    • 84880982652 scopus 로고    scopus 로고
    • Overactive bladder mediated by accelerated Ca2+ influx mode of Na+/Ca2+ exchanger in smooth muscle
    • Yamamura H, Cole WC, Kita S, et al. Overactive bladder mediated by accelerated Ca2+ influx mode of Na+/Ca2+ exchanger in smooth muscle. Am J Physiol Cell Physiol 2013;305:C299-C308.
    • (2013) Am J Physiol Cell Physiol , vol.305
    • Yamamura, H.1    Cole, W.C.2    Kita, S.3
  • 27
    • 84855542967 scopus 로고    scopus 로고
    • PPADS, a P2X receptor antagonist, as a novel inhibitor of the reverse mode of the Na+/Ca2+ exchanger in guinea pig airway smooth muscle
    • Flores-Soto E, Reyes-García J, Sommer B, Chavez J, Barajas-López C, Montaño LM. PPADS, a P2X receptor antagonist, as a novel inhibitor of the reverse mode of the Na+/Ca2+ exchanger in guinea pig airway smooth muscle. Eur J Pharmacol 2012;674:439-444.
    • (2012) Eur J Pharmacol , vol.674 , pp. 439-444
    • Flores-Soto, E.1    Reyes-García, J.2    Sommer, B.3    Chavez, J.4    Barajas-López, C.5    Montaño, L.M.6
  • 28
    • 57049138368 scopus 로고    scopus 로고
    • Effects of clenbuterol on contractility and Ca2+ homeostasis of isolated rat ventricular myocytes
    • Siedlecka U, Arora M, Kolettis T, et al. Effects of clenbuterol on contractility and Ca2+ homeostasis of isolated rat ventricular myocytes. Am J Physiol Heart Circ Physiol 2008;295:H1917-H1926.
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Siedlecka, U.1    Arora, M.2    Kolettis, T.3
  • 29
    • 39749171161 scopus 로고    scopus 로고
    • Role and possible mechanisms of clenbuterol in enhancing reverse remodelling during mechanical unloading in murine heart failure
    • Soppa GKR, Lee J, Stagg MA, et al. Role and possible mechanisms of clenbuterol in enhancing reverse remodelling during mechanical unloading in murine heart failure. Cardiovasc Res 2008;77:695.
    • (2008) Cardiovasc Res , vol.77 , pp. 695
    • Soppa, G.K.R.1    Lee, J.2    Stagg, M.A.3
  • 30
    • 0010011921 scopus 로고    scopus 로고
    • Measurement of cardiac mechanical function in isolated ventricular myocytes from rats and mice by computerized video-based imaging
    • Ren J, Wold LE. Measurement of cardiac mechanical function in isolated ventricular myocytes from rats and mice by computerized video-based imaging. Biol Proced Online 2001;3:43.
    • (2001) Biol Proced Online , vol.3 , pp. 43
    • Ren, J.1    Wold, L.E.2
  • 31
    • 34248163595 scopus 로고    scopus 로고
    • Direct effects of apelin on cardiomyocyte contractility and electrophysiology
    • Farkasfalvi K, Stagg MA, Coppen SR, et al. Direct effects of apelin on cardiomyocyte contractility and electrophysiology. Biochem Biophys Res Commun 2007;357:889.
    • (2007) Biochem Biophys Res Commun , vol.357 , pp. 889
    • Farkasfalvi, K.1    Stagg, M.A.2    Coppen, S.R.3
  • 32
    • 3242723417 scopus 로고    scopus 로고
    • The effects of overexpression of the Na+/Ca2+ exchanger on calcium regulation in hypertrophied mouse cardiac myocytes
    • Stagg MA, Malik AH, MacLeod KT, Terracciano CMN. The effects of overexpression of the Na+/Ca2+ exchanger on calcium regulation in hypertrophied mouse cardiac myocytes. Cell Calcium 2004;36:111.
    • (2004) Cell Calcium , vol.36 , pp. 111
    • Stagg, M.A.1    Malik, A.H.2    MacLeod, K.T.3    Terracciano, C.M.N.4
  • 33
    • 0030915842 scopus 로고    scopus 로고
    • Effects of lactate on the relative contribution of Ca2 extrusion mechanisms to relaxation in guinea-pig ventricular myocytes
    • Terracciano CM, MacLeod KT. Effects of lactate on the relative contribution of Ca2 extrusion mechanisms to relaxation in guinea-pig ventricular myocytes. J Physiol 1997;500(Pt 3):557.
    • (1997) J Physiol , vol.500 , Issue.PART 3 , pp. 557
    • Terracciano, C.M.1    MacLeod, K.T.2
  • 34
    • 0029142771 scopus 로고
    • Effects of rest interval on the release of calcium from the sarcoplasmic reticulum in isolated guinea pig ventricular myocytes
    • Terracciano CM, Naqvi RU, MacLeod KT. Effects of rest interval on the release of calcium from the sarcoplasmic reticulum in isolated guinea pig ventricular myocytes. Circ Res 1995;77:354-360.
    • (1995) Circ Res , vol.77 , pp. 354-360
    • Terracciano, C.M.1    Naqvi, R.U.2    MacLeod, K.T.3
  • 35
    • 47749107875 scopus 로고    scopus 로고
    • Prolonged mechanical unloading reduces myofilament sensitivity to calcium and sarcoplasmic reticulum calcium uptake leading to contractile dysfunction
    • Soppa GKR, Lee J, Stagg M, et al. Prolonged mechanical unloading reduces myofilament sensitivity to calcium and sarcoplasmic reticulum calcium uptake leading to contractile dysfunction. J Heart Lung Transplant 2008;27:882.
    • (2008) J Heart Lung Transplant , vol.27 , pp. 882
    • Soppa, G.K.R.1    Lee, J.2    Stagg, M.3
  • 36
    • 0028300397 scopus 로고
    • Relaxation in rabbit and rat cardiac cells: species-dependent differences in cellular mechanisms
    • Bassani JW, Bassani RA, Bers DM. Relaxation in rabbit and rat cardiac cells: species-dependent differences in cellular mechanisms. J Physiol 1994;476:279-293.
    • (1994) J Physiol , vol.476 , pp. 279-293
    • Bassani, J.W.1    Bassani, R.A.2    Bers, D.M.3
  • 37
    • 33845778948 scopus 로고    scopus 로고
    • Troponin phosphorylation and regulatory function in human heart muscle: dephosphorylation of Ser23/24 on troponin I could account for the contractile defect in end-stage heart failure
    • Messer AE, Jacques AM, Marston SB. Troponin phosphorylation and regulatory function in human heart muscle: dephosphorylation of Ser23/24 on troponin I could account for the contractile defect in end-stage heart failure. J Mol Cell Cardiol 2007;42:247-259.
    • (2007) J Mol Cell Cardiol , vol.42 , pp. 247-259
    • Messer, A.E.1    Jacques, A.M.2    Marston, S.B.3
  • 38
    • 0024472146 scopus 로고
    • Intracellular Ca2+ transients during rapid cooling contractures in guinea-pig ventricular myocytes
    • Bers DM, Bridge JH, Spitzer KW. Intracellular Ca2+ transients during rapid cooling contractures in guinea-pig ventricular myocytes. J Physiol 1989;417:537-553.
    • (1989) J Physiol , vol.417 , pp. 537-553
    • Bers, D.M.1    Bridge, J.H.2    Spitzer, K.W.3
  • 39
    • 0027374405 scopus 로고
    • The relative contributions of different intracellular and sarcolemmal systems to relaxation in rat ventricular myocytes
    • Negretti N, O'Neill SC, Eisner DA. The relative contributions of different intracellular and sarcolemmal systems to relaxation in rat ventricular myocytes. Cardiovasc Res 1993;27:1826-1830.
    • (1993) Cardiovasc Res , vol.27 , pp. 1826-1830
    • Negretti, N.1    O'Neill, S.C.2    Eisner, D.A.3
  • 40
    • 4844222685 scopus 로고    scopus 로고
    • Forefront of Na+/Ca2+ exchanger studies: molecular pharmacology of Na+/Ca2+ exchange inhibitors
    • Iwamoto T. Forefront of Na+/Ca2+ exchanger studies: molecular pharmacology of Na+/Ca2+ exchange inhibitors. J Pharmacol Sci 2004;96:27-32.
    • (2004) J Pharmacol Sci , vol.96 , pp. 27-32
    • Iwamoto, T.1
  • 41
    • 0028920614 scopus 로고
    • Calibration of indo-1 and resting intracellular [Ca]i in intact rabbit cardiac myocytes
    • Bassani JW, Bassani RA, Bers DM. Calibration of indo-1 and resting intracellular [Ca]i in intact rabbit cardiac myocytes. Biophys J 1995;68:1453.
    • (1995) Biophys J , vol.68 , pp. 1453
    • Bassani, J.W.1    Bassani, R.A.2    Bers, D.M.3
  • 42
    • 0031252785 scopus 로고    scopus 로고
    • Intracellular Ca2+ inactivates L-type Ca2+ channels with a Hill coefficient of approximately 1 and an inhibition constant of approximately 4 microM by reducing channel's open probability
    • Höfer GF, Hohenthanner K, Baumgartner W, et al. Intracellular Ca2+ inactivates L-type Ca2+ channels with a Hill coefficient of approximately 1 and an inhibition constant of approximately 4 microM by reducing channel's open probability. Biophys J 1997;73:1857-1865.
    • (1997) Biophys J , vol.73 , pp. 1857-1865
    • Höfer, G.F.1    Hohenthanner, K.2    Baumgartner, W.3
  • 43
    • 0025711107 scopus 로고
    • Sodium-calcium exchange in excitable cells: fuzzy space
    • Lederer WJ, Niggli E, Hadley RW. Sodium-calcium exchange in excitable cells: fuzzy space. Science 1990;248:283.
    • (1990) Science , vol.248 , pp. 283
    • Lederer, W.J.1    Niggli, E.2    Hadley, R.W.3
  • 44
    • 0020317428 scopus 로고
    • Calcium release in skinned cardiac cells: variations with species, tissues, and development
    • Fabiato A. Calcium release in skinned cardiac cells: variations with species, tissues, and development. Fed Proc 1982;41:2238-2244.
    • (1982) Fed Proc , vol.41 , pp. 2238-2244
    • Fabiato, A.1
  • 45
    • 0024582850 scopus 로고
    • Influence of temperature on the calcium sensitivity of the myofilaments of skinned ventricular muscle from the rabbit
    • Harrison SM, Bers DM. Influence of temperature on the calcium sensitivity of the myofilaments of skinned ventricular muscle from the rabbit. J Gen Physiol 1989;93:411-428.
    • (1989) J Gen Physiol , vol.93 , pp. 411-428
    • Harrison, S.M.1    Bers, D.M.2
  • 46
    • 62449234647 scopus 로고    scopus 로고
    • Myofilament dysfunction in cardiac disease from mice to men
    • Hamdani N, de Waard M, Messer AE, et al. Myofilament dysfunction in cardiac disease from mice to men. J Muscle Res Cell Motil 2008;29:189-201.
    • (2008) J Muscle Res Cell Motil , vol.29 , pp. 189-201
    • Hamdani, N.1    de Waard, M.2    Messer, A.E.3


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