Disruption of Calcium Homeostasis in Cardiomyocytes Underlies Cardiac Structural and Functional Changes in Severe Sepsis

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Celes, Mara R N ^a,b,c   Malvestio, Lygia M ^a   Suadicani, Sylvia O ^c   Prado, Cibele M ^a   Figueiredo, Maria J ^a   Campos, Erica C ^a   Freitas, Ana C S ^a   Spray, David C ^c   Tanowitz, Herbert B ^c   da Silva, João S ^a   Rossi, Marcos A ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF GOIÁS   (Brazil)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CALPAIN 1; DANTROLENE; DYSTROPHIN; F ACTIN; MYOSIN HEAVY CHAIN; PROTEASOME; TUBULIN; VERAPAMIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CARDIOMYOPATHY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISEASE SEVERITY; DRUG ACTIVITY; HEART CONTRACTION; HEART FUNCTION; HEART MUSCLE CELL; HEART PROTECTION; LYSOSOME; MALE; MORTALITY; MOUSE; NEWBORN; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SARCOMERE; SEPSIS; SEPTIC CARDIOMYOPATHY; SURVIVAL RATE; UBIQUITINATION;

ACTINS; ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; CALCIUM; CALPAIN; CECUM; CELLS, CULTURED; DANTROLENE; DYSTROPHIN; FLUORESCENT ANTIBODY TECHNIQUE; HEMODYNAMICS; HOMEOSTASIS; INTRACELLULAR SPACE; LIGATION; MICE; MICE, INBRED C57BL; MYOCARDIUM; MYOCYTES, CARDIAC; MYOSIN HEAVY CHAINS; PUNCTURES; SARCOMERES; SEPSIS; STROKE VOLUME; SURVIVAL ANALYSIS; VERAPAMIL;

EID: 84880713595     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0068809     Document Type: Article

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