The potential of asiaticoside for TGF-β1/Smad signaling inhibition in prevention and progression of hypoxia-induced pulmonary hypertension

Life Sciences

Volumn 137, Issue , 2015, Pages 56-64

  Wang, Xiao Bing ^a   Wang, Wu ^a   Zhu, Xiao Chun ^a   Ye, Wen Jing ^a   Cai, Hui ^a   Wu, Pei Liang ^a   Huang, Xiao Ying ^a   Wang, Liang Xing ^a  

^a WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Asiaticoside; Pulmonary arterial hypertension; Smad; TGF 1; Vascular remodeling

Indexed keywords

ASIATICOSIDE; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1; CASPASE 3; MADH2 PROTEIN, RAT; MADH3 PROTEIN, RAT; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRITERPENE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFECT; HEART RIGHT VENTRICLE HYPERTROPHY; HISTOPATHOLOGY; HYPOXIA-INDUCED PULMONARY HYPERTENSION; LUNG ARTERY PRESSURE; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PULMONARY ARTERY SMOOTH MUSCLE CELL; RAT; SIGNAL TRANSDUCTION; VASCULAR REMODELING; ANIMAL; ANOXIA; BIOSYNTHESIS; BLOOD PRESSURE; CELL MOTION; COMPLICATION; DRUG EFFECTS; HEART VENTRICLE; HYPERTENSION, PULMONARY; HYPERTROPHY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PULMONARY ARTERY;

ANIMALIA; CENTELLA ASIATICA; RATTUS;

ANIMALS; ANOXIA; APOPTOSIS; BLOOD PRESSURE; CASPASE 3; CELL MOVEMENT; CELL PROLIFERATION; DISEASE PROGRESSION; HEART VENTRICLES; HYPERTENSION, PULMONARY; HYPERTROPHY; MALE; PHOSPHORYLATION; PULMONARY ARTERY; RATS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TRITERPENES; VASCULAR REMODELING;

EID: 84938596127     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2015.07.016     Document Type: Article

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