Fibroblasts Rendered Antifibrotic, Antiapoptotic, and Angiogenic by Priming with Cardiosphere-Derived Extracellular Membrane Vesicles

Journal of the American College of Cardiology

Volumn 66, Issue 6, 2015, Pages 599-611

  Tseliou, Eleni ^a   Fouad, Joseph ^b   Reich, Heidi ^a   Slipczuk, Leandro ^a   De Couto, Geoffrey ^a   Aminzadeh, Mark ^a   Middleton, Ryan ^a   Valle, Jackelyn ^a   Weixin, Liu ^a   Marbán, Eduardo ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b HARVARD COLLEGE   (United States)

Author keywords

cardiac repair; conversion; exosome; growth factor

Indexed keywords

MICRORNA; STROMAL CELL DERIVED FACTOR 1; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN; ALBUMINOID; PB-127 COMPOUND; POLYESTER;

ALLOTRANSPLANTATION; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIAPOPTOTIC EFFECT; ANTIFIBROTIC EFFECT; ARTICLE; BIOLOGICAL ACTIVITY; CARDIOSPHERE DERIVED EXTRACELLULAR MEMBRANE VESICLE; CARDIOSPHERE DERIVED EXTRACELLULAR MEMBRANE VESICLE PRIMED DERMAL FIBROBLAST; CELL COMMUNICATION; CELL THERAPY; CONTROLLED STUDY; DOWN REGULATION; EXOSOME; FEMALE; HEART INFARCTION; HEART PROTECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MEMBRANE VESICLE; NEWBORN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; SKIN FIBROBLAST; ANIMAL; APOPTOSIS; BROWN NORWAY RAT; CELL CULTURE; CELL MEMBRANE; CLATHRIN-COATED VESICLE; FIBROBLAST; FIBROSIS; MYOCARDIAL INFARCTION; PATHOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TRANSPLANTATION; WISTAR KYOTO RAT;

ALBUMINS; ANIMALS; APOPTOSIS; CELL MEMBRANE; CELLS, CULTURED; CLATHRIN-COATED VESICLES; FEMALE; FIBROBLASTS; FIBROSIS; HUMANS; MALE; MYOCARDIAL INFARCTION; NEOVASCULARIZATION, PHYSIOLOGIC; POLYESTERS; RATS; RATS, INBRED BN; RATS, INBRED WKY; RATS, SPRAGUE-DAWLEY;

EID: 84938595605     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2015.05.068     Document Type: Article

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