메뉴 건너뛰기




Volumn 7, Issue 29, 2015, Pages 15777-15789

BMP-2 Derived Peptide and Dexamethasone Incorporated Mesoporous Silica Nanoparticles for Enhanced Osteogenic Differentiation of Bone Mesenchymal Stem Cells

Author keywords

bone morphogenetic peptide; cellular uptake; dexamethasone; mesoporous silica nanoparticles; osteogenic differentiation

Indexed keywords

CELL CULTURE; COMPUTERIZED TOMOGRAPHY; MESOPOROUS MATERIALS; NANOPARTICLES; PEPTIDES; PHOSPHATASES; POLYMER BLENDS; PROTEINS; SILICA; STEM CELLS; SYNTHESIS (CHEMICAL); TISSUE; TISSUE ENGINEERING; TISSUE REGENERATION;

EID: 84938572761     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/acsami.5b02636     Document Type: Article
Times cited : (194)

References (56)
  • 1
    • 34249693022 scopus 로고    scopus 로고
    • Biological and Mechanical Enhancement of Impacted Allograft Seeded with Human Bone Marrow Stromal Cells: Potential Clinical Role in Impaction Bone Grafting
    • Bolland, B. J.; Partridge, K.; Tilley, S.; New, A. M.; Dunlop, D. G.; Oreffo, R. O. Biological and Mechanical Enhancement of Impacted Allograft Seeded with Human Bone Marrow Stromal Cells: Potential Clinical Role in Impaction Bone Grafting Regener. Med. 2006, 1, 457-467 10.2217/17460751.1.4.457
    • (2006) Regener. Med. , vol.1 , pp. 457-467
    • Bolland, B.J.1    Partridge, K.2    Tilley, S.3    New, A.M.4    Dunlop, D.G.5    Oreffo, R.O.6
  • 3
    • 84862931627 scopus 로고    scopus 로고
    • Rapid Mineralization of Porous Gelatin Scaffolds by Electrodeposition for Bone Tissue Engineering
    • He, C. L.; Zhang, F.; Cao, L. J.; Feng, W.; Qiu, K. X.; Zhang, Y. Z.; Wang, H. S.; Mo, X. M.; Wang, J. W. Rapid Mineralization of Porous Gelatin Scaffolds by Electrodeposition for Bone Tissue Engineering J. Mater. Chem. 2012, 22, 2111-2119 10.1039/C1JM14631A
    • (2012) J. Mater. Chem. , vol.22 , pp. 2111-2119
    • He, C.L.1    Zhang, F.2    Cao, L.J.3    Feng, W.4    Qiu, K.X.5    Zhang, Y.Z.6    Wang, H.S.7    Mo, X.M.8    Wang, J.W.9
  • 4
    • 84873978765 scopus 로고    scopus 로고
    • Hydroxyapatite Nanoparticle Reinforced Peptide Amphiphile Nanomatrix Enhances the Osteogenic Differentiation of Mesenchymal Stem Cells by Compositional Ratios
    • Vines, J. B.; Lim, D.-J.; Anderson, J. M.; Jun, H.-W. Hydroxyapatite Nanoparticle Reinforced Peptide Amphiphile Nanomatrix Enhances the Osteogenic Differentiation of Mesenchymal Stem Cells by Compositional Ratios Acta Biomater. 2012, 8, 4053-4063 10.1016/j.actbio.2012.07.024
    • (2012) Acta Biomater. , vol.8 , pp. 4053-4063
    • Vines, J.B.1    Lim, D.-J.2    Anderson, J.M.3    Jun, H.-W.4
  • 5
    • 84888640380 scopus 로고    scopus 로고
    • Calcium Phosphate Deposition Rate, Structure and Osteoconductivity on Electrospun Poly(L-Lactic Acid) Matrix Using Electrodeposition or Simulated Body Fluid Incubation
    • He, C. L.; Jin, X. B.; Ma, P. X. Calcium Phosphate Deposition Rate, Structure and Osteoconductivity on Electrospun Poly(L-Lactic Acid) Matrix Using Electrodeposition or Simulated Body Fluid Incubation Acta Biomater. 2014, 10, 419-427 10.1016/j.actbio.2013.08.041
    • (2014) Acta Biomater. , vol.10 , pp. 419-427
    • He, C.L.1    Jin, X.B.2    Ma, P.X.3
  • 7
    • 84886092994 scopus 로고    scopus 로고
    • Hierarchical Mesoporous Silica Nanofibers as Multifunctional Scaffolds for Bone Tissue Regeneration
    • Ravichandran, R.; Gandhi, S.; Sundaramurthi, D.; Sethuraman, S.; Krishnan, U. M. Hierarchical Mesoporous Silica Nanofibers as Multifunctional Scaffolds for Bone Tissue Regeneration J. Biomater. Sci., Polym. Ed. 2013, 24, 1988-2005 10.1080/09205063.2013.816930
    • (2013) J. Biomater. Sci., Polym. Ed. , vol.24 , pp. 1988-2005
    • Ravichandran, R.1    Gandhi, S.2    Sundaramurthi, D.3    Sethuraman, S.4    Krishnan, U.M.5
  • 8
    • 79958142542 scopus 로고    scopus 로고
    • Stimulated Osteoblastic Proliferation by Mesoporous Silica Xerogel with High Specific Surface Area
    • Zhou, H.; Wu, X.; Wei, J.; Lu, X.; Zhang, S.; Shi, J.; Liu, C. Stimulated Osteoblastic Proliferation by Mesoporous Silica Xerogel with High Specific Surface Area J. Mater. Sci.: Mater. Med. 2011, 22, 731-739 10.1007/s10856-011-4239-1
    • (2011) J. Mater. Sci.: Mater. Med. , vol.22 , pp. 731-739
    • Zhou, H.1    Wu, X.2    Wei, J.3    Lu, X.4    Zhang, S.5    Shi, J.6    Liu, C.7
  • 9
    • 84887053107 scopus 로고    scopus 로고
    • Polyelectrolyte Multilayer Functionalized Mesoporous Silica Nanoparticles for pH-Responsive Drug Delivery: Layer Thickness-Dependent Release Profiles and Biocompatibility
    • Feng, W.; Zhou, X.; He, C.; Qiu, K.; Nie, W.; Chen, L.; Wang, H.; Mo, X.; Zhang, Y. Polyelectrolyte Multilayer Functionalized Mesoporous Silica Nanoparticles for pH-Responsive Drug Delivery: Layer Thickness-Dependent Release Profiles and Biocompatibility J. Mater. Chem. B 2013, 1, 5886-5898 10.1039/c3tb21193b
    • (2013) J. Mater. Chem. B , vol.1 , pp. 5886-5898
    • Feng, W.1    Zhou, X.2    He, C.3    Qiu, K.4    Nie, W.5    Chen, L.6    Wang, H.7    Mo, X.8    Zhang, Y.9
  • 10
    • 46749123819 scopus 로고    scopus 로고
    • Mesoporous Silica Nanoparticles as Controlled Release Drug Delivery and Gene Transfection Carriers
    • Slowing, I. I.; Vivero-Escoto, J. L.; Wu, C.-W.; Lin, V. S.-Y. Mesoporous Silica Nanoparticles as Controlled Release Drug Delivery and Gene Transfection Carriers Adv. Drug Delivery Rev. 2008, 60, 1278-1288 10.1016/j.addr.2008.03.012
    • (2008) Adv. Drug Delivery Rev. , vol.60 , pp. 1278-1288
    • Slowing, I.I.1    Vivero-Escoto, J.L.2    Wu, C.-W.3    Lin, V.S.-Y.4
  • 11
    • 84883004710 scopus 로고    scopus 로고
    • Doxorubicin-Loaded Electrospun Poly (L-Lactic Acid)/Mesoporous Silica Nanoparticles Composite Nanofibers for Potential Postsurgical Cancer Treatment
    • Qiu, K.; He, C.; Feng, W.; Wang, W.; Zhou, X.; Yin, Z.; Chen, L.; Wang, H.; Mo, X. Doxorubicin-Loaded Electrospun Poly (L-Lactic Acid)/Mesoporous Silica Nanoparticles Composite Nanofibers for Potential Postsurgical Cancer Treatment J. Mater. Chem. B 2013, 1, 4601-4611 10.1039/c3tb20636j
    • (2013) J. Mater. Chem. B , vol.1 , pp. 4601-4611
    • Qiu, K.1    He, C.2    Feng, W.3    Wang, W.4    Zhou, X.5    Yin, Z.6    Chen, L.7    Wang, H.8    Mo, X.9
  • 12
    • 84902491251 scopus 로고    scopus 로고
    • Effect of pH-Responsive Alginate/Chitosan Multilayers Coating on Delivery Efficiency, Cellular Uptake and Biodistribution of Mesoporous Silica Nanoparticles Based Nanocarriers
    • Feng, W.; Nie, W.; He, C.; Zhou, X.; Chen, L.; Qiu, K.; Wang, W.; Yin, Z. Effect of pH-Responsive Alginate/Chitosan Multilayers Coating on Delivery Efficiency, Cellular Uptake and Biodistribution of Mesoporous Silica Nanoparticles Based Nanocarriers ACS Appl. Mater. Interfaces 2014, 6, 8447-8460 10.1021/am501337s
    • (2014) ACS Appl. Mater. Interfaces , vol.6 , pp. 8447-8460
    • Feng, W.1    Nie, W.2    He, C.3    Zhou, X.4    Chen, L.5    Qiu, K.6    Wang, W.7    Yin, Z.8
  • 13
    • 34249780352 scopus 로고    scopus 로고
    • Mesoporous Silica Nanoparticles for Drug Delivery and Biosensing Applications
    • Slowing, I. I.; Trewyn, B. G.; Giri, S.; Lin, V. Y. Mesoporous Silica Nanoparticles for Drug Delivery and Biosensing Applications Adv. Funct. Mater. 2007, 17, 1225-1236 10.1002/adfm.200601191
    • (2007) Adv. Funct. Mater. , vol.17 , pp. 1225-1236
    • Slowing, I.I.1    Trewyn, B.G.2    Giri, S.3    Lin, V.Y.4
  • 14
    • 84908409356 scopus 로고    scopus 로고
    • Engineering of Biomimetic Nanofibrous Matrices for Drug Delivery and Tissue Engineering
    • He, C. L.; Nie, W.; Feng, W. Engineering of Biomimetic Nanofibrous Matrices for Drug Delivery and Tissue Engineering J. Mater. Chem. B 2014, 2, 7828-7848 10.1039/C4TB01464B
    • (2014) J. Mater. Chem. B , vol.2 , pp. 7828-7848
    • He, C.L.1    Nie, W.2    Feng, W.3
  • 15
    • 78149419122 scopus 로고    scopus 로고
    • Electrodeposition on Nanofibrous Polymer Scaffolds: Rapid Mineralization, Tunable Calcium Phosphate Composition and Topography
    • He, C. L.; Xiao, G. Y.; Jin, X. B.; Sun, C. H.; Ma, P. X. Electrodeposition on Nanofibrous Polymer Scaffolds: Rapid Mineralization, Tunable Calcium Phosphate Composition and Topography Adv. Funct. Mater. 2010, 20, 3568-3576 10.1002/adfm.201000993
    • (2010) Adv. Funct. Mater. , vol.20 , pp. 3568-3576
    • He, C.L.1    Xiao, G.Y.2    Jin, X.B.3    Sun, C.H.4    Ma, P.X.5
  • 16
    • 84870330878 scopus 로고    scopus 로고
    • Nanoparticles and Their Potential for Application in Bone
    • Tautzenberger, A.; Kovtun, A.; Ignatius, A. Nanoparticles and Their Potential for Application in Bone Int. J. Nanomed. 2012, 7, 4545-4557 10.2147/IJN.S34127
    • (2012) Int. J. Nanomed. , vol.7 , pp. 4545-4557
    • Tautzenberger, A.1    Kovtun, A.2    Ignatius, A.3
  • 17
    • 84904963574 scopus 로고    scopus 로고
    • Effective Immobilization of BMP-2 Mediated by Polydopamine Coating on Biodegradable Nanofibers for Enhanced in Vivo Bone Formation
    • Cho, H.-j.; Madhurakkat Perikamana, S. K.; Lee, J.-h.; Lee, J.; Lee, K.-M.; Shin, C. S.; Shin, H. Effective Immobilization of BMP-2 Mediated by Polydopamine Coating on Biodegradable Nanofibers for Enhanced in Vivo Bone Formation ACS Appl. Mater. Interfaces 2014, 6, 11225-11235 10.1021/am501391z
    • (2014) ACS Appl. Mater. Interfaces , vol.6 , pp. 11225-11235
    • Cho, H.-J.1    Madhurakkat Perikamana, S.K.2    Lee, J.-H.3    Lee, J.4    Lee, K.-M.5    Shin, C.S.6    Shin, H.7
  • 18
    • 84855454430 scopus 로고    scopus 로고
    • Controlled Release of Bone Morphogenetic Protein 2 and Dexamethasone Loaded in Core-Shell PLLACL-Collagen Fibers for Use in Bone Tissue Engineering
    • Su, Y.; Su, Q.; Liu, W.; Lim, M.; Venugopal, J. R.; Mo, X.; Ramakrishna, S.; Al-Deyab, S. S.; El-Newehy, M. Controlled Release of Bone Morphogenetic Protein 2 and Dexamethasone Loaded in Core-Shell PLLACL-Collagen Fibers for Use in Bone Tissue Engineering Acta Biomater. 2012, 8, 763-771 10.1016/j.actbio.2011.11.002
    • (2012) Acta Biomater. , vol.8 , pp. 763-771
    • Su, Y.1    Su, Q.2    Liu, W.3    Lim, M.4    Venugopal, J.R.5    Mo, X.6    Ramakrishna, S.7    Al-Deyab, S.S.8    El-Newehy, M.9
  • 19
    • 77957562066 scopus 로고    scopus 로고
    • Layer-by-Layer Assembly of β-Estradiol Loaded Mesoporous Silica Nanoparticles on Titanium Substrates and Its Implication for Bone Homeostasis
    • Hu, Y.; Cai, K. Y.; Luo, Z.; Jandt, K. D. Layer-by-Layer Assembly of β-Estradiol Loaded Mesoporous Silica Nanoparticles on Titanium Substrates and Its Implication for Bone Homeostasis Adv. Mater. 2010, 22, 4146-4150 10.1002/adma.201000854
    • (2010) Adv. Mater. , vol.22 , pp. 4146-4150
    • Hu, Y.1    Cai, K.Y.2    Luo, Z.3    Jandt, K.D.4
  • 20
    • 67449146883 scopus 로고    scopus 로고
    • Emerging Role of Bone Morphogenetic Proteins in Angiogenesis
    • David, L.; Feige, J.-J.; Bailly, S. Emerging Role of Bone Morphogenetic Proteins in Angiogenesis Cytokine Growth Factor Rev. 2009, 20, 203-212 10.1016/j.cytogfr.2009.05.001
    • (2009) Cytokine Growth Factor Rev. , vol.20 , pp. 203-212
    • David, L.1    Feige, J.-J.2    Bailly, S.3
  • 21
    • 0026757708 scopus 로고
    • The Healing of Segmental Bone Defects, Induced by Recombinant Human Bone Morphogenetic Protein (rhBMP-2). A Radiographic, Histological, and Biomechanical Study in Rats
    • Yasko, A. W.; Lane, J.; Fellinger, E.; Rosen, V.; Wozney, J.; Wang, E. The Healing of Segmental Bone Defects, Induced by Recombinant Human Bone Morphogenetic Protein (rhBMP-2). A Radiographic, Histological, and Biomechanical Study in Rats J. Bone Jt. Surg. Am. Vol. 1992, 74, 659-670
    • (1992) J. Bone Jt. Surg. Am. Vol. , vol.74 , pp. 659-670
    • Yasko, A.W.1    Lane, J.2    Fellinger, E.3    Rosen, V.4    Wozney, J.5    Wang, E.6
  • 22
    • 77956030370 scopus 로고    scopus 로고
    • Spinal Reconstruction and Bone Morphogenetic Proteins: Open Questions
    • Shimer, A. L.; Öner, F. C.; Vaccaro, A. R. Spinal Reconstruction and Bone Morphogenetic Proteins: Open Questions Injury 2009, 40, S32-S38 10.1016/S0020-1383(09)70009-9
    • (2009) Injury , vol.40 , pp. S32-S38
    • Shimer, A.L.1    Öner, F.C.2    Vaccaro, A.R.3
  • 23
    • 34547197434 scopus 로고    scopus 로고
    • Enhanced Bone Regeneration with BMP-2 Loaded Functional Nanoparticle-Hydrogel Complex
    • Chung, Y.-I.; Ahn, K.-M.; Jeon, S.-H.; Lee, S.-Y.; Lee, J.-H.; Tae, G. Enhanced Bone Regeneration with BMP-2 Loaded Functional Nanoparticle-Hydrogel Complex J. Controlled Release 2007, 121, 91-99 10.1016/j.jconrel.2007.05.029
    • (2007) J. Controlled Release , vol.121 , pp. 91-99
    • Chung, Y.-I.1    Ahn, K.-M.2    Jeon, S.-H.3    Lee, S.-Y.4    Lee, J.-H.5    Tae, G.6
  • 25
    • 77954485528 scopus 로고    scopus 로고
    • Hydroxyapatite Nanoparticles as a Controlled-Release Carrier of BMP-2: Absorption and Release Kinetics in Vitro
    • Xie, G.; Sun, J.; Zhong, G.; Liu, C.; Wei, J. Hydroxyapatite Nanoparticles as a Controlled-Release Carrier of BMP-2: Absorption and Release Kinetics in Vitro J. Mater. Sci.: Mater. Med. 2010, 21, 1875-1880 10.1007/s10856-010-4038-0
    • (2010) J. Mater. Sci.: Mater. Med. , vol.21 , pp. 1875-1880
    • Xie, G.1    Sun, J.2    Zhong, G.3    Liu, C.4    Wei, J.5
  • 26
    • 84887358348 scopus 로고    scopus 로고
    • BMP2-Loaded Nanoporous Silica Nanoparticles Promote Osteogenic Differentiation of Human Mesenchymal Stem Cells
    • Neumann, A.; Christel, A.; Kasper, C.; Behrens, P. BMP2-Loaded Nanoporous Silica Nanoparticles Promote Osteogenic Differentiation of Human Mesenchymal Stem Cells RSC Adv. 2013, 3, 24222-24230 10.1039/c3ra44734k
    • (2013) RSC Adv. , vol.3 , pp. 24222-24230
    • Neumann, A.1    Christel, A.2    Kasper, C.3    Behrens, P.4
  • 27
    • 84923869710 scopus 로고    scopus 로고
    • A Dual-Delivery System of pH-Responsive Chitosan-Functionalized Mesoporous Silica Nanoparticles Bearing BMP-2 and Dexamethasone for Enhanced Bone Regeneration
    • Gan, Q.; Zhu, J.; Yuan, Y.; Liu, H.; Qian, J.; Li, Y.; Liu, C. A Dual-Delivery System of pH-Responsive Chitosan-Functionalized Mesoporous Silica Nanoparticles Bearing BMP-2 and Dexamethasone for Enhanced Bone Regeneration J. Mater. Chem. B 2015, 3, 2056-2066 10.1039/C4TB01897D
    • (2015) J. Mater. Chem. B , vol.3 , pp. 2056-2066
    • Gan, Q.1    Zhu, J.2    Yuan, Y.3    Liu, H.4    Qian, J.5    Li, Y.6    Liu, C.7
  • 28
    • 84879495981 scopus 로고    scopus 로고
    • Peptide Decorated Nano-Hydroxyapatite with Enhanced Bioactivity and Osteogenic Differentiation Via Polydopamine Coating
    • Sun, Y.; Deng, Y.; Ye, Z.; Liang, S.; Tang, Z.; Wei, S. Peptide Decorated Nano-Hydroxyapatite with Enhanced Bioactivity and Osteogenic Differentiation Via Polydopamine Coating Colloids Surf., B 2013, 111, 107-116 10.1016/j.colsurfb.2013.05.037
    • (2013) Colloids Surf., B , vol.111 , pp. 107-116
    • Sun, Y.1    Deng, Y.2    Ye, Z.3    Liang, S.4    Tang, Z.5    Wei, S.6
  • 29
    • 84903718628 scopus 로고    scopus 로고
    • Incorporating the BMP-2 Peptide in Genetically-Engineered Biomaterials Accelerates Osteogenic Differentiation
    • Kim, Y.; Renner, J. N.; Liu, J. C. Incorporating the BMP-2 Peptide in Genetically-Engineered Biomaterials Accelerates Osteogenic Differentiation Biomater. Sci. 2014, 2, 1110-1119 10.1039/C3BM60333D
    • (2014) Biomater. Sci. , vol.2 , pp. 1110-1119
    • Kim, Y.1    Renner, J.N.2    Liu, J.C.3
  • 30
    • 0642341968 scopus 로고    scopus 로고
    • Activation of Osteo-Progenitor Cells by a Novel Synthetic Peptide Derived from the Bone Morphogenetic Protein-2 Knuckle Epitope
    • Saito, A.; Suzuki, Y.; Ogata, S.-i.; Ohtsuki, C.; Tanihara, M. Activation of Osteo-Progenitor Cells by a Novel Synthetic Peptide Derived from the Bone Morphogenetic Protein-2 Knuckle Epitope Biochim. Biophys. Acta, Proteins Proteomics 2003, 1651, 60-67 10.1016/S1570-9639(03)00235-8
    • (2003) Biochim. Biophys. Acta, Proteins Proteomics , vol.1651 , pp. 60-67
    • Saito, A.1    Suzuki, Y.2    Ogata, S.-I.3    Ohtsuki, C.4    Tanihara, M.5
  • 31
    • 3042727188 scopus 로고    scopus 로고
    • Prolonged Ectopic Calcification Induced by BMP-2-Derived Synthetic Peptide
    • Saito, A.; Suzuki, Y.; Ogata, S. I.; Ohtsuki, C.; Tanihara, M. Prolonged Ectopic Calcification Induced by BMP-2-Derived Synthetic Peptide J. Biomed. Mater. Res. 2004, 70, 115-121 10.1002/jbm.a.30071
    • (2004) J. Biomed. Mater. Res. , vol.70 , pp. 115-121
    • Saito, A.1    Suzuki, Y.2    Ogata, S.I.3    Ohtsuki, C.4    Tanihara, M.5
  • 32
    • 56449125956 scopus 로고    scopus 로고
    • Effect of Grafting RGD and BMP-2 Protein-Derived Peptides to a Hydrogel Substrate on Osteogenic Differentiation of Marrow Stromal Cells
    • He, X.; Ma, J.; Jabbari, E. Effect of Grafting RGD and BMP-2 Protein-Derived Peptides to a Hydrogel Substrate on Osteogenic Differentiation of Marrow Stromal Cells Langmuir 2008, 24, 12508-12516 10.1021/la802447v
    • (2008) Langmuir , vol.24 , pp. 12508-12516
    • He, X.1    Ma, J.2    Jabbari, E.3
  • 33
    • 33845878147 scopus 로고    scopus 로고
    • Repair of 20-Mm Long Rabbit Radial Bone Defects Using BMP-Derived Peptide Combined with an α-Tricalcium Phosphate Scaffold
    • Saito, A.; Suzuki, Y.; Kitamura, M.; Ogata, S. I.; Yoshihara, Y.; Masuda, S.; Ohtsuki, C.; Tanihara, M. Repair of 20-Mm Long Rabbit Radial Bone Defects Using BMP-Derived Peptide Combined with an α-Tricalcium Phosphate Scaffold J. Biomed. Mater. Res., Part A 2006, 77, 700-706 10.1002/jbm.a.30662
    • (2006) J. Biomed. Mater. Res., Part A , vol.77 , pp. 700-706
    • Saito, A.1    Suzuki, Y.2    Kitamura, M.3    Ogata, S.I.4    Yoshihara, Y.5    Masuda, S.6    Ohtsuki, C.7    Tanihara, M.8
  • 34
    • 84869842199 scopus 로고    scopus 로고
    • Coating with a Modular Bone Morphogenetic Peptide Promotes Healing of a Bone-Implant Gap in an Ovine Model
    • Lu, Y.; Lee, J. S.; Nemke, B.; Graf, B. K.; Royalty, K.; Illgen, R., III; Vanderby, R., Jr; Markel, M. D.; Murphy, W. L. Coating with a Modular Bone Morphogenetic Peptide Promotes Healing of a Bone-Implant Gap in an Ovine Model PLoS One 2012, 7, e50378 10.1371/journal.pone.0050378
    • (2012) PLoS One , vol.7
    • Lu, Y.1    Lee, J.S.2    Nemke, B.3    Graf, B.K.4    Royalty, K.5    Illgen, R.6    Vanderby, R.7    Markel, M.D.8    Murphy, W.L.9
  • 35
    • 84864299413 scopus 로고    scopus 로고
    • Osteogenesis Induced by a Bone Forming Peptide from the Prodomain Region of BMP-7
    • Kim, H. K.; Kim, J. H.; Park, D. S.; Park, K. S.; Kang, S. S.; Lee, J. S.; Jeong, M. H.; Yoon, T. R. Osteogenesis Induced by a Bone Forming Peptide from the Prodomain Region of BMP-7 Biomaterials 2012, 33, 7057-7063 10.1016/j.biomaterials.2012.06.036
    • (2012) Biomaterials , vol.33 , pp. 7057-7063
    • Kim, H.K.1    Kim, J.H.2    Park, D.S.3    Park, K.S.4    Kang, S.S.5    Lee, J.S.6    Jeong, M.H.7    Yoon, T.R.8
  • 36
    • 6044238264 scopus 로고    scopus 로고
    • A Polyamidoamine Dendrimer-Capped Mesoporous Silica Nanosphere-Based Gene Transfection Reagent
    • Radu, D. R.; Lai, C.-Y.; Jeftinija, K.; Rowe, E. W.; Jeftinija, S.; Lin, V. S.-Y. A Polyamidoamine Dendrimer-Capped Mesoporous Silica Nanosphere-Based Gene Transfection Reagent J. Am. Chem. Soc. 2004, 126, 13216-13217 10.1021/ja046275m
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 13216-13217
    • Radu, D.R.1    Lai, C.-Y.2    Jeftinija, K.3    Rowe, E.W.4    Jeftinija, S.5    Lin, V.S.-Y.6
  • 37
    • 84859343412 scopus 로고    scopus 로고
    • Nuclear-Targeted Drug Delivery of TAT Peptide-Conjugated Monodisperse Mesoporous Silica Nanoparticles
    • Pan, L.; He, Q.; Liu, J.; Chen, Y.; Ma, M.; Zhang, L.; Shi, J. Nuclear-Targeted Drug Delivery of TAT Peptide-Conjugated Monodisperse Mesoporous Silica Nanoparticles J. Am. Chem. Soc. 2012, 134, 5722-5725 10.1021/ja211035w
    • (2012) J. Am. Chem. Soc. , vol.134 , pp. 5722-5725
    • Pan, L.1    He, Q.2    Liu, J.3    Chen, Y.4    Ma, M.5    Zhang, L.6    Shi, J.7
  • 38
    • 72449133772 scopus 로고    scopus 로고
    • Small Intestine Submucosa Sponge for in Vivo Support of Tissue-Engineered Bone Formation in the Presence of Rat Bone Marrow Stem Cells
    • Kim, K. S.; Lee, J. Y.; Kang, Y. M.; Kim, E.; Kim, G. H.; Rhee, S. D.; Cheon, H. G.; Kim, J. H.; Min, B.-H.; Lee, H. B. Small Intestine Submucosa Sponge for in Vivo Support of Tissue-Engineered Bone Formation in the Presence of Rat Bone Marrow Stem Cells Biomaterials 2010, 31, 1104-1113 10.1016/j.biomaterials.2009.10.020
    • (2010) Biomaterials , vol.31 , pp. 1104-1113
    • Kim, K.S.1    Lee, J.Y.2    Kang, Y.M.3    Kim, E.4    Kim, G.H.5    Rhee, S.D.6    Cheon, H.G.7    Kim, J.H.8    Min, B.-H.9    Lee, H.B.10
  • 39
    • 77956191832 scopus 로고    scopus 로고
    • Differentiation of Pre-Osteoblast Cells on Poly (Ethylene Terephthalate) Grafted with RGD and/or BMPs Mimetic Peptides
    • Zouani, O. F.; Chollet, C.; Guillotin, B.; Durrieu, M.-C. Differentiation of Pre-Osteoblast Cells on Poly (Ethylene Terephthalate) Grafted with RGD and/or BMPs Mimetic Peptides Biomaterials 2010, 31, 8245-8253 10.1016/j.biomaterials.2010.07.042
    • (2010) Biomaterials , vol.31 , pp. 8245-8253
    • Zouani, O.F.1    Chollet, C.2    Guillotin, B.3    Durrieu, M.-C.4
  • 40
    • 80052929287 scopus 로고    scopus 로고
    • A Biocompatible Drug Delivery Nanovalve System on the Surface of Mesoporous Nanoparticles
    • Du, L.; Song, H. Y.; Liao, S. J. A Biocompatible Drug Delivery Nanovalve System on the Surface of Mesoporous Nanoparticles Microporous Mesoporous Mater. 2012, 147, 200-204 10.1016/j.micromeso.2011.06.020
    • (2012) Microporous Mesoporous Mater. , vol.147 , pp. 200-204
    • Du, L.1    Song, H.Y.2    Liao, S.J.3
  • 41
    • 84904437698 scopus 로고    scopus 로고
    • Synthesis of Hollow Mesoporous Silica Nanoparticles with Tunable Shell Thickness and Pore Size Using Amphiphilic Block Copolymers as Core Templates
    • Zhou, X.; Cheng, X.; Feng, W.; Qiu, K.; Chen, L.; Nie, W.; Yin, Z.; Mo, X.; Wang, H.; He, C. Synthesis of Hollow Mesoporous Silica Nanoparticles with Tunable Shell Thickness and Pore Size Using Amphiphilic Block Copolymers as Core Templates Dalton Trans. 2014, 43, 11834-11842 10.1039/C4DT01138D
    • (2014) Dalton Trans. , vol.43 , pp. 11834-11842
    • Zhou, X.1    Cheng, X.2    Feng, W.3    Qiu, K.4    Chen, L.5    Nie, W.6    Yin, Z.7    Mo, X.8    Wang, H.9    He, C.10
  • 42
    • 84863666975 scopus 로고    scopus 로고
    • Tumor Cell Targeted Delivery by Specific Peptide-Modified Mesoporous Silica Nanoparticles
    • Wang, Y.; Shi, W.; Song, W.; Wang, L.; Liu, X.; Chen, J.; Huang, R. Tumor Cell Targeted Delivery by Specific Peptide-Modified Mesoporous Silica Nanoparticles J. Mater. Chem. 2012, 22, 14608-14616 10.1039/c2jm32398b
    • (2012) J. Mater. Chem. , vol.22 , pp. 14608-14616
    • Wang, Y.1    Shi, W.2    Song, W.3    Wang, L.4    Liu, X.5    Chen, J.6    Huang, R.7
  • 43
    • 78049351024 scopus 로고    scopus 로고
    • Core/Shell Structured Hollow Mesoporous Nanocapsules: A Potential Platform for Simultaneous Cell Imaging and Anticancer Drug Delivery
    • Chen, Y.; Chen, H.; Zeng, D.; Tian, Y.; Chen, F.; Feng, J.; Shi, J. Core/Shell Structured Hollow Mesoporous Nanocapsules: A Potential Platform for Simultaneous Cell Imaging and Anticancer Drug Delivery ACS Nano 2010, 4, 6001-6013 10.1021/nn1015117
    • (2010) ACS Nano , vol.4 , pp. 6001-6013
    • Chen, Y.1    Chen, H.2    Zeng, D.3    Tian, Y.4    Chen, F.5    Feng, J.6    Shi, J.7
  • 45
    • 84904201170 scopus 로고    scopus 로고
    • Free and Copolymerized γ-Cyclodextrins Regulate Performance of Dexamethasone-Loaded Dextran Microspheres for Bone Regeneration
    • Lima, A. C.; Puga, A. M.; Mano, J. F.; Concheiro, A.; Alvarez-Lorenzo, C. Free and Copolymerized γ-Cyclodextrins Regulate Performance of Dexamethasone-Loaded Dextran Microspheres for Bone Regeneration J. Mater. Chem. B 2014, 2, 4943-4956 10.1039/C3TB21665A
    • (2014) J. Mater. Chem. B , vol.2 , pp. 4943-4956
    • Lima, A.C.1    Puga, A.M.2    Mano, J.F.3    Concheiro, A.4    Alvarez-Lorenzo, C.5
  • 47
    • 0031761638 scopus 로고    scopus 로고
    • Glucocorticoid-Induced Osteoporosis: Both in Vivo and in Vitro Concentrations of Glucocorticoids Higher Than Physiological Levels Attenuate Osteoblast Differentiation
    • Ishida, Y.; Heersche, J. N. M. Glucocorticoid-Induced Osteoporosis: Both in Vivo and in Vitro Concentrations of Glucocorticoids Higher Than Physiological Levels Attenuate Osteoblast Differentiation J. Bone Miner. Res. 1998, 13, 1822-1826 10.1359/jbmr.1998.13.12.1822
    • (1998) J. Bone Miner. Res. , vol.13 , pp. 1822-1826
    • Ishida, Y.1    Heersche, J.N.M.2
  • 48
    • 0034285013 scopus 로고    scopus 로고
    • The Osteoblast: A Sophisticated Fibroblast under Central Surveillance
    • Ducy, P.; Schinke, T.; Karsenty, G. The Osteoblast: A Sophisticated Fibroblast under Central Surveillance Science 2000, 289, 1501-1504 10.1126/science.289.5484.1501
    • (2000) Science , vol.289 , pp. 1501-1504
    • Ducy, P.1    Schinke, T.2    Karsenty, G.3
  • 49
    • 32044468546 scopus 로고    scopus 로고
    • Phosphorylation, Acetylation and Ubiquitination: The Molecular Basis of Runx Regulation
    • Bae, S.-C.; Lee, Y. H. Phosphorylation, Acetylation and Ubiquitination: The Molecular Basis of Runx Regulation Gene 2006, 366, 58-66 10.1016/j.gene.2005.10.017
    • (2006) Gene , vol.366 , pp. 58-66
    • Bae, S.-C.1    Lee, Y.H.2
  • 50
    • 7644220887 scopus 로고    scopus 로고
    • Skeletal Hormones and the C/EBP and Runx Transcription Factors: Interactions That Integrate and Redefine Gene Expression
    • Centrella, M.; Christakos, S.; McCarthy, T. L. Skeletal Hormones and the C/EBP and Runx Transcription Factors: Interactions That Integrate and Redefine Gene Expression Gene 2004, 342, 13-24 10.1016/j.gene.2004.06.036
    • (2004) Gene , vol.342 , pp. 13-24
    • Centrella, M.1    Christakos, S.2    McCarthy, T.L.3
  • 51
    • 84891635564 scopus 로고    scopus 로고
    • Effect of Grafting BMP2-Derived Peptide to Nanoparticles on Osteogenic and Vasculogenic Expression of Stromal Cells
    • Mercado, A. E.; Yang, X.; He, X.; Jabbari, E. Effect of Grafting BMP2-Derived Peptide to Nanoparticles on Osteogenic and Vasculogenic Expression of Stromal Cells J. Tissue Eng. Regener. Med. 2014, 8, 15-28 10.1002/term.1487
    • (2014) J. Tissue Eng. Regener. Med. , vol.8 , pp. 15-28
    • Mercado, A.E.1    Yang, X.2    He, X.3    Jabbari, E.4
  • 52
    • 84887922423 scopus 로고    scopus 로고
    • Effects of Dexamethasone, Ascorbic Acid and β-Glycerophosphate on the Osteogenic Differentiation of Stem Cells in Vitro
    • Langenbach, F.; Handschel, J. Effects of Dexamethasone, Ascorbic Acid and β-Glycerophosphate on the Osteogenic Differentiation of Stem Cells in Vitro Stem Cell Res. Ther. 2013, 4, 117 10.1186/scrt328
    • (2013) Stem Cell Res. Ther. , vol.4 , pp. 117
    • Langenbach, F.1    Handschel, J.2
  • 53
    • 12344291865 scopus 로고    scopus 로고
    • Bone Morphogenetic Proteins
    • Chen, D.; Zhao, M.; Mundy, G. R. Bone Morphogenetic Proteins Growth Factors 2004, 22, 233-41 10.1080/08977190412331279890
    • (2004) Growth Factors , vol.22 , pp. 233-241
    • Chen, D.1    Zhao, M.2    Mundy, G.R.3
  • 55
    • 0030804095 scopus 로고    scopus 로고
    • Stimulatory Effects of Basic Fibroblast Growth Factor and Bone Morphogenetic Protein-2 on Osteogenic Differentiation of Rat Bone Marrow-Derived Mesenchymal Stem Cells
    • Hanada, K.; Dennis, J. E.; Caplan, A. I. Stimulatory Effects of Basic Fibroblast Growth Factor and Bone Morphogenetic Protein-2 on Osteogenic Differentiation of Rat Bone Marrow-Derived Mesenchymal Stem Cells J. Bone Miner. Res. 1997, 12, 1606-1614 10.1359/jbmr.1997.12.10.1606
    • (1997) J. Bone Miner. Res. , vol.12 , pp. 1606-1614
    • Hanada, K.1    Dennis, J.E.2    Caplan, A.I.3
  • 56
    • 0032994043 scopus 로고    scopus 로고
    • Signal Transduction by Bone Morphogenetic Protein Receptors: Functional Roles of SMAD Proteins
    • Miyazono, K. Signal Transduction by Bone Morphogenetic Protein Receptors: Functional Roles of SMAD Proteins Bone 1999, 25, 91-93 10.1016/S8756-3282(99)00113-1
    • (1999) Bone , vol.25 , pp. 91-93
    • Miyazono, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.