메뉴 건너뛰기




Volumn 5, Issue , 2015, Pages

Mutant p53 promotes ovarian cancer cell adhesion to mesothelial cells via integrin β4 and Akt signals

Author keywords

[No Author keywords available]

Indexed keywords

BETA4 INTEGRIN; ITGB4 PROTEIN, HUMAN; PROTEIN KINASE B; PROTEIN P53; TP53 PROTEIN, HUMAN;

EID: 84938521972     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep12642     Document Type: Article
Times cited : (56)

References (54)
  • 1
    • 34047207337 scopus 로고    scopus 로고
    • TP53 mutations in human cancers: Functional selection and impact on cancer prognosis and outcomes
    • Petitjean, A., Achatz, M. I., Borresen-Dale, A. L., Hainaut, P. & Olivier, M. TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes. Oncogene 26, 2157-2165 (2007).
    • (2007) Oncogene , vol.26 , pp. 2157-2165
    • Petitjean, A.1    Achatz, M.I.2    Borresen-Dale, A.L.3    Hainaut, P.4    Olivier, M.5
  • 2
    • 0018372204 scopus 로고
    • Stage II carcinoma of the endometrium
    • Surwit, E. A. et al. Stage II carcinoma of the endometrium. Int J Radiat Oncol Biol Phys 5, 323-326 (1979).
    • (1979) Int J Radiat Oncol Biol Phys , vol.5 , pp. 323-326
    • Surwit, E.A.1
  • 3
    • 0027210981 scopus 로고
    • Gain of function mutations in p53
    • Dittmer, D. et al. Gain of function mutations in p53. Nat Genet 4, 42-46 (1993).
    • (1993) Nat Genet , vol.4 , pp. 42-46
    • Dittmer, D.1
  • 4
    • 81355154522 scopus 로고    scopus 로고
    • Mutant p53 gain of function is interwoven into the hallmarks of cancer
    • Solomon, H., Madar, S. & Rotter, V. Mutant p53 gain of function is interwoven into the hallmarks of cancer. J Pathol 225, 475-478 (2011).
    • (2011) J Pathol , vol.225 , pp. 475-478
    • Solomon, H.1    Madar, S.2    Rotter, V.3
  • 7
    • 77955363995 scopus 로고    scopus 로고
    • TP53 mutations in human cancers: Origins, consequences, and clinical use
    • Olivier, M., Hollstein, M. & Hainaut, P. TP53 mutations in human cancers: origins, consequences, and clinical use. Cold Spring Harb Perspect Biol 2, a001008 (2010).
    • (2010) Cold Spring Harb Perspect Biol , vol.2 , pp. a001008
    • Olivier, M.1    Hollstein, M.2    Hainaut, P.3
  • 8
    • 0020582447 scopus 로고
    • P53, a transformation-related cellular-encoded protein, can be used as a biochemical marker for the detection of primary mouse tumor cells
    • Rotter, V. p53, a transformation-related cellular-encoded protein, can be used as a biochemical marker for the detection of primary mouse tumor cells. Proc Natl Acad Sci USA 80, 2613-2617 (1983).
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 2613-2617
    • Rotter, V.1
  • 9
    • 0026760566 scopus 로고
    • Abnormal structure and expression of the p53 gene in human ovarian carcinoma cell lines
    • Yaginuma, Y. & Westphal, H. Abnormal structure and expression of the p53 gene in human ovarian carcinoma cell lines. Cancer Res 52, 4196-4199 (1992).
    • (1992) Cancer Res , vol.52 , pp. 4196-4199
    • Yaginuma, Y.1    Westphal, H.2
  • 10
    • 48649090161 scopus 로고    scopus 로고
    • Jagged-1 and notch3 juxtacrine loop regulates ovarian tumor growth and adhesion
    • Choi, J. H. et al. Jagged-1 and Notch3 juxtacrine loop regulates ovarian tumor growth and adhesion. Cancer Res 68, 5716-5723 (2008).
    • (2008) Cancer Res , vol.68 , pp. 5716-5723
    • Choi, J.H.1
  • 11
    • 7444242670 scopus 로고    scopus 로고
    • HMOCC-1, a human monoclonal antibody that inhibits adhesion of ovarian cancer cells to human mesothelial cells
    • Suzuki, N. et al. HMOCC-1, a human monoclonal antibody that inhibits adhesion of ovarian cancer cells to human mesothelial cells. Gynecol Oncol 95, 290-298 (2004).
    • (2004) Gynecol Oncol , vol.95 , pp. 290-298
    • Suzuki, N.1
  • 12
    • 0027369120 scopus 로고
    • Increased accumulation of p53 protein in cisplatin-resistant ovarian cell lines
    • Brown, R. et al. Increased accumulation of p53 protein in cisplatin-resistant ovarian cell lines. Int J Cancer 55, 678-684 (1993).
    • (1993) Int J Cancer , vol.55 , pp. 678-684
    • Brown, R.1
  • 13
    • 0031036695 scopus 로고    scopus 로고
    • P53 status does not affect sensitivity of human ovarian cancer cell lines to paclitaxel
    • Debernardis, D. et al. p53 status does not affect sensitivity of human ovarian cancer cell lines to paclitaxel. Cancer Res 57, 870-874 (1997).
    • (1997) Cancer Res , vol.57 , pp. 870-874
    • Debernardis, D.1
  • 14
    • 61449220945 scopus 로고    scopus 로고
    • Genetic and cell biological analysis of integrin outside-in signaling
    • Legate, K. R., Wickstrom, S. A. & Fassler, R. Genetic and cell biological analysis of integrin outside-in signaling. Genes Dev 23, 397-418 (2009).
    • (2009) Genes Dev , vol.23 , pp. 397-418
    • Legate, K.R.1    Wickstrom, S.A.2    Fassler, R.3
  • 15
    • 0029915884 scopus 로고    scopus 로고
    • Expression of alpha 6 and beta 4 integrins in serous ovarian carcinoma correlates with expression of the basement membrane protein laminin
    • Skubitz, A. P., Bast, R. C., Jr., Wayner, E. A., Letourneau, P. C. & Wilke, M. S. Expression of alpha 6 and beta 4 integrins in serous ovarian carcinoma correlates with expression of the basement membrane protein laminin. Am J Pathol 148, 1445-1461 (1996).
    • (1996) Am J Pathol , vol.148 , pp. 1445-1461
    • Skubitz, A.P.1    Bast, R.C.2    Wayner, E.A.3    Letourneau, P.C.4    Wilke, M.S.5
  • 16
    • 84867875608 scopus 로고    scopus 로고
    • Targeting ILK and beta4 integrin abrogates the invasive potential of ovarian cancer
    • Choi, Y. P., Kim, B. G., Gao, M. Q., Kang, S. & Cho, N. H. Targeting ILK and beta4 integrin abrogates the invasive potential of ovarian cancer. Biochem Biophys Res Commun 427, 642-648 (2012).
    • (2012) Biochem Biophys Res Commun , vol.427 , pp. 642-648
    • Choi, Y.P.1    Kim, B.G.2    Gao, M.Q.3    Kang, S.4    Cho, N.H.5
  • 17
    • 0035816533 scopus 로고    scopus 로고
    • The breast cancer beta 4 integrin and endothelial human CLCA2 mediate lung metastasis
    • Abdel-Ghany, M., Cheng, H. C., Elble, R. C. & Pauli, B. U. The breast cancer beta 4 integrin and endothelial human CLCA2 mediate lung metastasis. J Biol Chem 276, 25438-25446 (2001).
    • (2001) J Biol Chem , vol.276 , pp. 25438-25446
    • Abdel-Ghany, M.1    Cheng, H.C.2    Elble, R.C.3    Pauli, B.U.4
  • 18
    • 4344576356 scopus 로고    scopus 로고
    • Adhesion of HT-29 colon carcinoma cells to endothelial cells requires sequential events involving E-selectin and integrin beta4
    • Laferriere, J., Houle, F. & Huot, J. Adhesion of HT-29 colon carcinoma cells to endothelial cells requires sequential events involving E-selectin and integrin beta4. Clin Exp Metastasis 21, 257-264 (2004).
    • (2004) Clin Exp Metastasis , vol.21 , pp. 257-264
    • Laferriere, J.1    Houle, F.2    Huot, J.3
  • 19
    • 34047093817 scopus 로고    scopus 로고
    • Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: Role of the beta4 integrin and the PI3k pathway
    • Baril, P. et al. Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: role of the beta4 integrin and the PI3k pathway. Oncogene 26, 2082-2094 (2007).
    • (2007) Oncogene , vol.26 , pp. 2082-2094
    • Baril, P.1
  • 20
    • 67651005198 scopus 로고    scopus 로고
    • Negative regulation of beta4 integrin transcription by homeodomain-interacting protein kinase 2 and p53 impairs tumor progression
    • Bon, G. et al. Negative regulation of beta4 integrin transcription by homeodomain-interacting protein kinase 2 and p53 impairs tumor progression. Cancer Res 69, 5978-5986 (2009).
    • (2009) Cancer Res , vol.69 , pp. 5978-5986
    • Bon, G.1
  • 21
    • 33748286819 scopus 로고    scopus 로고
    • Integrin-regulated FAK-src signaling in normal and cancer cells
    • Mitra, S. K. & Schlaepfer, D. D. Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr Opin Cell Biol 18, 516-523 (2006).
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 516-523
    • Mitra, S.K.1    Schlaepfer, D.D.2
  • 22
    • 0036544562 scopus 로고    scopus 로고
    • Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling
    • Eliceiri, B. P. et al. Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling. J Cell Biol 157, 149-160 (2002).
    • (2002) J Cell Biol , vol.157 , pp. 149-160
    • Eliceiri, B.P.1
  • 23
    • 0041700142 scopus 로고    scopus 로고
    • Phase III multicenter randomized trial of amifostine as cytoprotectant in first-line chemotherapy in ovarian cancer patients
    • Lorusso, D. et al. Phase III multicenter randomized trial of amifostine as cytoprotectant in first-line chemotherapy in ovarian cancer patients. Ann Oncol 14, 1086-1093 (2003).
    • (2003) Ann Oncol , vol.14 , pp. 1086-1093
    • Lorusso, D.1
  • 24
    • 34447298354 scopus 로고    scopus 로고
    • Pattern and prognostic factors in patients with malignant ascites: A retrospective study
    • Ayantunde, A. A. & Parsons, S. L. Pattern and prognostic factors in patients with malignant ascites: a retrospective study. Ann Oncol 18, 945-949 (2007).
    • (2007) Ann Oncol , vol.18 , pp. 945-949
    • Ayantunde, A.A.1    Parsons, S.L.2
  • 25
    • 84874786083 scopus 로고    scopus 로고
    • Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion
    • Muller, P. A. et al. Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion. Oncogene 32, 1252-1265 (2013).
    • (2013) Oncogene , vol.32 , pp. 1252-1265
    • Muller, P.A.1
  • 26
    • 47249116180 scopus 로고    scopus 로고
    • Conditional RNA interference in vivo to study mutant p53 oncogenic gain of function on tumor malignancy
    • Bossi, G. et al. Conditional RNA interference in vivo to study mutant p53 oncogenic gain of function on tumor malignancy. Cell Cycle 7, 1870-1879 (2008).
    • (2008) Cell Cycle , vol.7 , pp. 1870-1879
    • Bossi, G.1
  • 27
    • 0033747336 scopus 로고    scopus 로고
    • A gain of function p53 mutant promotes both genomic instability and cell survival in a novel p53-null mammary epithelial cell model
    • Murphy, K. L., Dennis, A. P. & Rosen, J. M. A gain of function p53 mutant promotes both genomic instability and cell survival in a novel p53-null mammary epithelial cell model. FASEB J 14, 2291-2302 (2000).
    • (2000) FASEB J , vol.14 , pp. 2291-2302
    • Murphy, K.L.1    Dennis, A.P.2    Rosen, J.M.3
  • 28
    • 42549099010 scopus 로고    scopus 로고
    • Lung specific expression of a human mutant p53 affects cell proliferation in transgenic mice
    • Duan, W., Gao, L., Jin, D., Otterson, G. A. & Villalona-Calero, M. A. Lung specific expression of a human mutant p53 affects cell proliferation in transgenic mice. Transgenic Res 17, 355-366 (2008).
    • (2008) Transgenic Res , vol.17 , pp. 355-366
    • Duan, W.1    Gao, L.2    Jin, D.3    Otterson, G.A.4    Villalona-Calero, M.A.5
  • 29
    • 0037050213 scopus 로고    scopus 로고
    • Hetero-oligomerization does not compromise 'gain of function' of tumor-derived p53 mutants
    • Deb, D. et al. Hetero-oligomerization does not compromise 'gain of function' of tumor-derived p53 mutants. Oncogene 21, 176-189 (2002).
    • (2002) Oncogene , vol.21 , pp. 176-189
    • Deb, D.1
  • 30
    • 0032574788 scopus 로고    scopus 로고
    • An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control
    • Gualberto, A., Aldape, K., Kozakiewicz, K. & Tlsty, T. D. An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control. Proc Natl Acad Sci USA 95, 5166-5171 (1998).
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 5166-5171
    • Gualberto, A.1    Aldape, K.2    Kozakiewicz, K.3    Tlsty, T.D.4
  • 31
    • 63049136592 scopus 로고    scopus 로고
    • A mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis
    • Adorno, M. et al. A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis. Cell 137, 87-98 (2009).
    • (2009) Cell , vol.137 , pp. 87-98
    • Adorno, M.1
  • 32
    • 67349166210 scopus 로고    scopus 로고
    • P53 controls cancer cell invasion by inducing the MDM2-mediated degradation of slug
    • Wang, S. P. et al. p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug. Nat Cell Biol 11, 694-704 (2009).
    • (2009) Nat Cell Biol , vol.11 , pp. 694-704
    • Wang, S.P.1
  • 33
    • 71049146802 scopus 로고    scopus 로고
    • Elevated expression of p53 gain-of-function mutation R175H in endometrial cancer cells can increase the invasive phenotypes by activation of the EGFR/PI3K/AKT pathway
    • Dong, P., Xu, Z., Jia, N., Li, D. & Feng, Y. Elevated expression of p53 gain-of-function mutation R175H in endometrial cancer cells can increase the invasive phenotypes by activation of the EGFR/PI3K/AKT pathway. Molecular Cancer 8, 103 (2009).
    • (2009) Molecular Cancer , vol.8 , pp. 103
    • Dong, P.1    Xu, Z.2    Jia, N.3    Li, D.4    Feng, Y.5
  • 34
    • 84863045363 scopus 로고    scopus 로고
    • Gain-of-function mutant p53 upregulates CXC chemokines and enhances cell migration
    • Yeudall, W. A. et al. Gain-of-function mutant p53 upregulates CXC chemokines and enhances cell migration. Carcinogenesis 33, 442-451 (2012).
    • (2012) Carcinogenesis , vol.33 , pp. 442-451
    • Yeudall, W.A.1
  • 35
    • 78650831903 scopus 로고    scopus 로고
    • Mutant p53 R248Q but not R248W enhances in vitro invasiveness of human lung cancer NCI-H1299 cells
    • Yoshikawa, K. et al. Mutant p53 R248Q but not R248W enhances in vitro invasiveness of human lung cancer NCI-H1299 cells. Biomedical Research 31, 401-411 (2010).
    • (2010) Biomedical Research , vol.31 , pp. 401-411
    • Yoshikawa, K.1
  • 36
    • 84871881742 scopus 로고    scopus 로고
    • Mutant p53 in cell adhesion and motility
    • Yeudall, W. A., Wrighton, K. H. & Deb, S. Mutant p53 in cell adhesion and motility. Methods Mol Biol 962, 135-146 (2013).
    • (2013) Methods Mol Biol , vol.962 , pp. 135-146
    • Yeudall, W.A.1    Wrighton, K.H.2    Deb, S.3
  • 37
    • 7044224706 scopus 로고    scopus 로고
    • Mutational spectrum of p53 mutations in primary breast and ovarian tumors
    • Feki, A. & Irminger-Finger, I. Mutational spectrum of p53 mutations in primary breast and ovarian tumors. Crit Rev Oncol Hematol 52, 103-116 (2004).
    • (2004) Crit Rev Oncol Hematol , vol.52 , pp. 103-116
    • Feki, A.1    Irminger-Finger, I.2
  • 38
    • 60849136310 scopus 로고    scopus 로고
    • P53 hot-spot mutants increase tumor vascularization via ROS-mediated activation of the HIF1/VEGF-A pathway
    • Khromova, N. V., Kopnin, P. B., Stepanova, E. V., Agapova, L. S. & Kopnin, B. P. p53 hot-spot mutants increase tumor vascularization via ROS-mediated activation of the HIF1/VEGF-A pathway. Cancer Lett 276, 143-151 (2009).
    • (2009) Cancer Lett , vol.276 , pp. 143-151
    • Khromova, N.V.1    Kopnin, P.B.2    Stepanova, E.V.3    Agapova, L.S.4    Kopnin, B.P.5
  • 39
    • 34247329362 scopus 로고    scopus 로고
    • P53 gain-of-function cancer mutants induce genetic instability by inactivating ATM
    • Song, H., Hollstein, M. & Xu, Y. p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM. Nature Cell Biology 9, 573-580 (2007).
    • (2007) Nature Cell Biology , vol.9 , pp. 573-580
    • Song, H.1    Hollstein, M.2    Xu, Y.3
  • 40
    • 1842862755 scopus 로고    scopus 로고
    • TP53 mutation spectra and load: A tool for generating hypotheses on the etiology of cancer
    • Olivier, M., Hussain, S. P., Caron de Fromentel, C., Hainaut, P. & Harris, C. C. TP53 mutation spectra and load: a tool for generating hypotheses on the etiology of cancer. IARC Sci Publ 157, 247-270 (2004).
    • (2004) IARC Sci Publ , vol.157 , pp. 247-270
    • Olivier, M.1    Hussain, S.P.2    Caron De-Fromentel, C.3    Hainaut, P.4    Harris, C.C.5
  • 41
    • 0027983669 scopus 로고
    • Crystal structure of a p53 tumor suppressor-DNA complex: Understanding tumorigenic mutations
    • Cho, Y., Gorina, S., Jeffrey, P. D. & Pavletich, N. P. Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science 265, 346-355 (1994).
    • (1994) Science , vol.265 , pp. 346-355
    • Cho, Y.1    Gorina, S.2    Jeffrey, P.D.3    Pavletich, N.P.4
  • 42
    • 70349443284 scopus 로고    scopus 로고
    • When mutants gain new powers: News from the mutant p53 field
    • Brosh, R. & Rotter, V. When mutants gain new powers: news from the mutant p53 field. Nature Review Cancer 9, 701-713 (2009).
    • (2009) Nature Review Cancer , vol.9 , pp. 701-713
    • Brosh, R.1    Rotter, V.2
  • 43
    • 0037145037 scopus 로고    scopus 로고
    • Integrins: Bidirectional, allosteric signaling machines
    • Hynes, R. O. Integrins: bidirectional, allosteric signaling machines. Cell 110, 673-687 (2002).
    • (2002) Cell , vol.110 , pp. 673-687
    • Hynes, R.O.1
  • 44
    • 77956495728 scopus 로고    scopus 로고
    • Ovarian cancer development and metastasis
    • Lengyel, E. Ovarian cancer development and metastasis. Am J Pathol 177, 1053-1064 (2010).
    • (2010) Am J Pathol , vol.177 , pp. 1053-1064
    • Lengyel, E.1
  • 45
    • 42049107076 scopus 로고    scopus 로고
    • Loss of E-cadherin promotes ovarian cancer metastasis via alpha 5-integrin, which is a therapeutic target
    • Sawada, K. et al. Loss of E-cadherin promotes ovarian cancer metastasis via alpha 5-integrin, which is a therapeutic target. Cancer Res 68, 2329-2339 (2008).
    • (2008) Cancer Res , vol.68 , pp. 2329-2339
    • Sawada, K.1
  • 46
    • 60549088136 scopus 로고    scopus 로고
    • Vascular cell adhesion molecule-1 is a regulator of ovarian cancer peritoneal metastasis
    • Slack-Davis, J. K., Atkins, K. A., Harrer, C., Hershey, E. D. & Conaway, M. Vascular cell adhesion molecule-1 is a regulator of ovarian cancer peritoneal metastasis. Cancer Res 69, 1469-1476 (2009).
    • (2009) Cancer Res , vol.69 , pp. 1469-1476
    • Slack-Davis, J.K.1    Atkins, K.A.2    Harrer, C.3    Hershey, E.D.4    Conaway, M.5
  • 47
  • 48
    • 84907197654 scopus 로고    scopus 로고
    • Ovarian cancer cell line panel (OCCP): Clinical importance of in vitro morphological subtypes
    • Beaufort, C. M. et al. Ovarian cancer cell line panel (OCCP): clinical importance of in vitro morphological subtypes. PloS one 9, e103988 (2014).
    • (2014) PloS One , vol.9 , pp. e103988
    • Beaufort, C.M.1
  • 49
    • 0041353453 scopus 로고    scopus 로고
    • Characterization of the p53 mutants ability to inhibit p73 beta transactivation using a yeast-based functional assay
    • Monti, P. et al. Characterization of the p53 mutants ability to inhibit p73 beta transactivation using a yeast-based functional assay. Oncogene 22, 5252-5260 (2003).
    • (2003) Oncogene , vol.22 , pp. 5252-5260
    • Monti, P.1
  • 50
    • 18544364361 scopus 로고    scopus 로고
    • Physical interaction with human tumor-derived p53 mutants inhibits p63 activities
    • Strano, S. et al. Physical interaction with human tumor-derived p53 mutants inhibits p63 activities. J Biol Chem 277, 18817-18826 (2002).
    • (2002) J Biol Chem , vol.277 , pp. 18817-18826
    • Strano, S.1
  • 51
    • 0032735443 scopus 로고    scopus 로고
    • HGF induces FAK activation and integrin-mediated adhesion in MTLn3 breast carcinoma cells
    • Beviglia, L. & Kramer, R. H. HGF induces FAK activation and integrin-mediated adhesion in MTLn3 breast carcinoma cells. Int J Cancer 83, 640-649 (1999).
    • (1999) Int J Cancer , vol.83 , pp. 640-649
    • Beviglia, L.1    Kramer, R.H.2
  • 52
    • 84860250156 scopus 로고    scopus 로고
    • PI3K/Akt signalling is required for the attachment and spreading, and growth in vivo of metastatic scirrhous gastric carcinoma
    • Matsuoka, T. et al. PI3K/Akt signalling is required for the attachment and spreading, and growth in vivo of metastatic scirrhous gastric carcinoma. Br J Cancer 106, 1535-1542 (2012).
    • (2012) Br J Cancer , vol.106 , pp. 1535-1542
    • Matsuoka, T.1
  • 53
    • 20444430061 scopus 로고    scopus 로고
    • Beta ig-h3 induces keratinocyte differentiation via modulation of involucrin and transglutaminase expression through the integrin alpha3beta1 and the phosphatidylinositol 3-kinase/Akt signaling pathway
    • Oh, J. E., Kook, J. K. & Min, B. M. Beta ig-h3 induces keratinocyte differentiation via modulation of involucrin and transglutaminase expression through the integrin alpha3beta1 and the phosphatidylinositol 3-kinase/Akt signaling pathway. J Biol Chem 280, 21629-21637 (2005).
    • (2005) J Biol Chem , vol.280 , pp. 21629-21637
    • Oh, J.E.1    Kook, J.K.2    Min, B.M.3
  • 54
    • 41349115432 scopus 로고    scopus 로고
    • The DAVID gene functional classification tool: A novel biological module-centric algorithm to functionally analyze large gene lists
    • Huang da, W. et al. The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists. Genome Biol 8, R183 (2007).
    • (2007) Genome Biol , vol.8 , pp. R183
    • Huang da, W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.