Adhesion of HT-29 colon carcinoma cells to endothelial cells requires sequential events involving E-selectin and integrin β4

Clinical and Experimental Metastasis

Volumn 21, Issue 3, 2004, Pages 257-265

  Laferrière, Julie ^a,b   Houle, François ^a   Huot, Jacques ^a  

^a LAVAL UNIVERSITY   (Canada)

^b CENTRE DE BIOCHIMIE   (France)

Author keywords

adhesion; E selectin; integrin 4; migration

Indexed keywords

ALPHA2 INTEGRIN; ALPHA3 INTEGRIN; ALPHA6 INTEGRIN; BETA1 INTEGRIN; BETA4 INTEGRIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; TUMOR NECROSIS FACTOR ALPHA; VERY LATE ACTIVATION ANTIGEN 5;

ANTIBODY SPECIFICITY; ARTICLE; CARCINOMA CELL; CELL ACTIVATION; CELL ADHESION; CELL MIGRATION; COLON CARCINOMA; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE DELETION; HUMAN; HUMAN CELL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UMBILICAL VEIN;

CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELLS, CULTURED; COLONIC NEOPLASMS; E-SELECTIN; ENDOTHELIUM, VASCULAR; HUMANS; INTEGRIN BETA4; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 4344576356     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:CLIN.0000037708.09420.9a     Document Type: Article

References (38)

1. Fidler IJ. The pathogenesis of cancer metastasis: The 'seed and soil' hypothesis revisited. Nat Rev Cancer 2003; 3: 453-8.
2. Meyer T, Hart IR. Mechanisms of tumour metastasis. Eur J Cancer 1998; 34: 214-21.
3. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm. Cell 1994; 76: 301-14.
4. Vestweber D, Blanks, JE. Mechanisms that regulate the function of the selectins and their ligands. Physiol Rev 1999; 79: 181-213.
5. Kim I, Moon SO, Kim SH et al. Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cells. J Biol Chem 1999; 276: 7614-20.
6. Takada A, Ohmori K, Yoneda T et al. Contribution of carbohydrate antigens sialyl Lewis A and sialyl Lewis X to adhesion of human cancer cells to vascular endothelium. Cancer Res 1993; 53: 354-61.
7. Sawada R, Tsuboi S, Fukuda M. Differential E-selectin-dependent adhesion efficiency in sublines of a human colon cancer exhibiting distinct metastatic potentials. J Biol Chem 1994; 269: 1425-31.
8. Kobayashi K, Matsumoto S, Morishima T et al. Cimetidine inhibits cancer cell adhesion to endothelial cells and prevents metastasis by blocking E-selectin expression. Cancer Res 2000; 60: 3978-84.
9. Khatib AM, Fallavollita L, Wancewicz EV et al. Inhibition of hepatic endothelial E-selectin expression by C-raf antisense oligonucleotides blocks colorectal carcinoma liver metastasis. Cancer Res 2002; 62: 5393-8.
10. Soltesz SA, Powers EA, Geng JG, Fisher C. Adhesion of HT-29 colon carcinoma cells to E-selectin results in increased tyrosine phosphorylation and decreased activity of c-src. Int J Cancer 1997; 77: 645-53.
11. Flugy AM, D'Amato M, Russo D et al. E-selectin modulates the malignant properties of T84 colon carcinoma cells. Biochem Biophys Res Commun 2002; 293: 1099-106.
12. D'Amato M, Flugy AM, Alaimo G et al. Role of calcium in E-selectin induced phenotype of T84 colon carcinoma cells. Biochem Biophys Res Commun 2003; 301: 907-14.
13. Laferriere J, Houle F, Taher MM et al. Transendothelial migration of colon carcinoma cells requires expression of E-selectin by endothelial cells and activation of stress-activated protein kinase-2 (SAPK2/p38) in the tumor cells. J Biol Chem 2001; 276: 33762-72.
14. Simon SI, Hu Y, Vestweber D, Smith CW. Neutrophil tethering on E-selectin activates beta 2 integrin binding to ICAM-1 through a mitogen-activated protein kinase signal transduction pathway. J Immunol 2002; 164: 4348-58.
15. van der Flier A, Sonnenberg A. Function and interactions of integrins. Cell Tissue Res 2001; 305: 285-98.
16. Hynes RO. Integrins: Bidirectional, allosteric signaling machines. Cell 2002; 110: 673-87.
17. Mercurio AM, Rabinovitz I. Towards a mechanistic understanding of tumor invasion - lessons from the alpha6beta 4 integrin. Semin Cancer Biol 2001; 11: 129-41.
18. Mercurio AM, Rabinovitz I, Shaw LM. The alpha 6 beta 4 integrin and epithelial cell migration. Curr Opin Cell Biol 2001; 13: 541-5.
19. Gambaletta D, Marchetti A, Benedetti L et al. Cooperative signaling between alpha(6)beta(4) integrin and ErbB-2 receptor is required to promote phosphatidylinositol 3-kinase-dependent invasion. J Biol Chem 2000; 275: 10604-10.
20. Shaw LM, Rabinovitz I, Wang HH et al. Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion. Cell 1997; 91: 949-60.
21. Trusolino L, Bertotti A, Comoglio PM. A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growth. Cell 2001; 107: 643-54.
22. Rezniczek GA, de Pereda JM, Reipert S, Wiche G. Linking integrin alpha6beta4-based cell adhesion to the intermediate filament cytoskeleton: Direct interaction between the beta4 subunit and plectin at multiple molecular sites. J Cell Biol 1998; 141: 209-25.
23. Dans M, Gagnoux-Palacios L, Blaikie P et al. Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates She signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes. J Biol Chem 2001; 276: 1494-502.
24. Masson-Gadais B, Houle F, Laferriere J, Huot J. Integrin alphavbeta3, requirement for VEGFR2-mediated activation of SAPK2/p38 and for Hsp90-dependent phosphorylation of focal adhesion kinase in endothelial cells activated by VEGF. Cell Stress Chaperones 2003; 8: 37-52.
25. Haier J, Nasralla M, Nicolson GL. Different adhesion properties of highly and poorly metastatic HT-29 colon carcinoma cells with extracellular matrix components: Role of integrin expression and cytoskeletal components. Br J Cancer 1999; 80: 1867-74.
26. Laferriere J, Houle F, Huot J. Regulation of the metastatic process by E-selectin and stress-activated protein kinase-2/p38. Ann NY Acad Sci 2002; 973: 562-72.
27. Rabinovitz I, Gipson IK, Mercurio AM. Traction forces mediated by alpha6beta4 integrin: Implications for basement membrane organization and tumor invasion. Mol Biol Cell 2001; 12: 4030-43.
28. Ruchaud-Sparagano MH, Walker TR, Rossi AG et al. Soluble E-selectin acts in synergy with platelet-activating factor to activate neutrophil beta 2-integrins. Role of tyrosine kinases and Ca2+ mobilization. J Biol Chem 2000; 275: 15758-64.
29. Burdick MM, McCaffery JM, Kim YS, Bochner BS, Konstantopoulos K. Colon carcinoma cell glycolipids, integrins, and other glycoproteins mediate adhesion to HUVECs under flow. Am J Physiol Cell Physiol 2003; 284: C977-87.
30. Ebert E.C. Mechanisms of colon cancer binding to substratum and cells. Dig Dis Sci 1996; 41: 1551-6.
31. Khatib AM, Kontogiannea M, Fallavollita L et al. Rapid induction of cytokine and E-selectin expression in the liver in response to metastatic tumor cells. Cancer Res 1999; 59: 1356-61.
32. Simiantonaki N, Jayasinghe C, Kirkpatrick CJ. Effect of proinflammatory stimuli on tumor cell-mediated induction of endothelial cell adhesion molecules in vitro. Exp Mol Pathol 2002; 73: 46-53.
33. O'Connor KL, Shaw LM, Mercurio AM. Release of cAMP gating by the alpha6beta4 integrin stimulates lamellae formation and the chemotactic migration of invasive carcinoma cells. J Cell Biol 1998; 143: 1749-60.
34. Abdel-Ghany M, Cheng HC, Elble RC, Pauli BU. The breast cancer beta 4 integrin and endothelial human CLCA2 mediate lung metastasis. J Biol Chem 2001; 276: 25438-46.
35. Muller, A., Homey, B., Soto et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001; 410: 50-6.
36. Mercurio AM. Invasive skin carcinoma - Ras and alpha6beta4 integrin lead the way. Cancer Cell 2003; 3: 201-2.
37. Abdel-Ghany M, Cheng HC, Elble RC, Pauli BU. Focal adhesion kinase activated by beta(4) integrin ligation to mCLCA1 mediates early metastatic growth. J Biol Chem 2002; 277: 34391-100.
38. Chambers AF, Groom AC, MacDonald IC. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2002; 2: 563-72.