-
1
-
-
19844373387
-
Epidemiology of lung cancer: Looking to the future
-
Alberg AJ, Brock MV, Samet JM (2005) Epidemiology of lung cancer: looking to the future. J Clin Oncol 23:3175-3185
-
(2005)
J Clin Oncol
, vol.23
, pp. 3175-3185
-
-
Alberg, A.J.1
Brock, M.V.2
Samet, J.M.3
-
2
-
-
0032523932
-
Wild-type and mutant forms of p53 activate human topoisomerase I: A possible mechanism for gain of function in mutants
-
Albor A, Kaku S, Kulesz-Martin M (1998) Wild-type and mutant forms of p53 activate human topoisomerase I: a possible mechanism for gain of function in mutants. Cancer Res 58:2091-2094
-
(1998)
Cancer Res
, vol.58
, pp. 2091-2094
-
-
Albor, A.1
Kaku, S.2
Kulesz-Martin, M.3
-
3
-
-
0026686753
-
Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53
-
Bargonetti J, Reynisdottir I, Friedman PN, Prives C (1992) Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53. Genes Dev 6:1886-1898
-
(1992)
Genes Dev
, vol.6
, pp. 1886-1898
-
-
Bargonetti, J.1
Reynisdottir, I.2
Friedman, P.N.3
Prives, C.4
-
4
-
-
0033552948
-
Mutant p53 gain of function: Differential effects of different p53 mutants on resistance of cultured cells to chemotherapy
-
Blandino G, Levine AJ, Oren M (1999) Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy. Oncogene 18:477-485
-
(1999)
Oncogene
, vol.18
, pp. 477-485
-
-
Blandino, G.1
Levine, A.J.2
Oren, M.3
-
5
-
-
0029097759
-
Radiation-induced cell cycle arrest compromised by p21 deficiency
-
Brugarolas J, Chandrasekaran C, Gordon JL, Beach D, Jacks T, Hannon GJ (1995) Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 377:552-557
-
(1995)
Nature
, vol.377
, pp. 552-557
-
-
Brugarolas, J.1
Chandrasekaran, C.2
Gordon, J.L.3
Beach, D.4
Jacks, T.5
Hannon, G.J.6
-
6
-
-
0035797473
-
Tissue specific expression of p53 target genes suggests a key role for KILLER/DR5 in p53-dependent apoptosis in vivo
-
Burns TF, Bernhard EJ, El-Deiry WS (2001) Tissue specific expression of p53 target genes suggests a key role for KILLER/DR5 in p53-dependent apoptosis in vivo. Oncogene 20:4601-4612
-
(2001)
Oncogene
, vol.20
, pp. 4601-4612
-
-
Burns, T.F.1
Bernhard, E.J.2
El-Deiry, W.S.3
-
7
-
-
0032556952
-
P21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells
-
Cayrol C, Knibiehler M, Ducommun B (1998) p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells. Oncogene 16:311-320
-
(1998)
Oncogene
, vol.16
, pp. 311-320
-
-
Cayrol, C.1
Knibiehler, M.2
Ducommun, B.3
-
8
-
-
0027983669
-
Crystal structure of a p53 tumor suppressor-DNA complex: Understanding tumorigenic mutations
-
Cho Y, Gorina S, Jeffrey PD, Pavletich NP (1994) Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science 265:346-355
-
(1994)
Science
, vol.265
, pp. 346-355
-
-
Cho, Y.1
Gorina, S.2
Jeffrey, P.D.3
Pavletich, N.P.4
-
9
-
-
0026508613
-
High frequency of somatically acquired p53 mutations in small-cell lung cancer cell lines and tumors
-
D'Amico D, Carbone D, Mitsudomi T, Nau M, Fedorko J, Russell E, Johnson B, Buchhagen D, Bodner S, Phelps R, Gazdar A, Minna JD (1992) High frequency of somatically acquired p53 mutations in small-cell lung cancer cell lines and tumors. Oncogene 7:339-346
-
(1992)
Oncogene
, vol.7
, pp. 339-346
-
-
D'Amico, D.1
Carbone, D.2
Mitsudomi, T.3
Nau, M.4
Fedorko, J.5
Russell, E.6
Johnson, B.7
Buchhagen, D.8
Bodner, S.9
Phelps, R.10
Gazdar, A.11
Minna, J.D.12
-
10
-
-
0027210981
-
Gain of function mutations in p53
-
Dittmer D, Pati S, Zambetti G, Chu S, Teresky AK, Moore M, Finlay C, Levine AJ (1993) Gain of function mutations in p53. Nat Genet 4:42-46
-
(1993)
Nat Genet
, vol.4
, pp. 42-46
-
-
Dittmer, D.1
Pati, S.2
Zambetti, G.3
Chu, S.4
Teresky, A.K.5
Moore, M.6
Finlay, C.7
Levine, A.J.8
-
11
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
-
Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montgomery CA Jr, Butel JS, Bradley A (1992) Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356:215-221
-
(1992)
Nature
, vol.356
, pp. 215-221
-
-
Donehower, L.A.1
Harvey, M.2
Slagle, B.L.3
McArthur, M.J.4
Montgomery Jr., C.A.5
Butel, J.S.6
Bradley, A.7
-
12
-
-
0037038671
-
Lung-specific expression of human mutant p53-273H is associated with a high frequency of lung adenocarcinoma in transgenic mice
-
Duan W, Ding H, Subler MA, Zhu WG, Zhang H, Stoner GD, Windle JJ, Otterson GA, Villalona-Calero MA (2002a) Lung-specific expression of human mutant p53-273H is associated with a high frequency of lung adenocarcinoma in transgenic mice. Oncogene 21:7831-7838
-
(2002)
Oncogene
, vol.21
, pp. 7831-7838
-
-
Duan, W.1
Ding, H.2
Subler, M.A.3
Zhu, W.G.4
Zhang, H.5
Stoner, G.D.6
Windle, J.J.7
Otterson, G.A.8
Villalona-Calero, M.A.9
-
13
-
-
0036076972
-
RT-PCR heteroduplex analysis permits differentiation of transgene and host gene expression in a transgenic animal model
-
Duan W, Ding H, Zhu WG, Srinivasan K, Ottersom GA, Villalona-Calero MA (2002b) RT-PCR heteroduplex analysis permits differentiation of transgene and host gene expression in a transgenic animal model. Biotechniques 33:58-66
-
(2002)
Biotechniques
, vol.33
, pp. 58-66
-
-
Duan, W.1
Ding, H.2
Zhu, W.G.3
Srinivasan, K.4
Ottersom, G.A.5
Villalona-Calero, M.A.6
-
14
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
El-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B (1993) WAF1, a potential mediator of p53 tumor suppression. Cell 75:817-825
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
15
-
-
0036605971
-
Induction of gene amplification as a gain-of-function phenotype of mutant p53 proteins
-
El-Hizawi S, Lagowski JP, Kulesz-Martin M, Albor A (2002) Induction of gene amplification as a gain-of-function phenotype of mutant p53 proteins. Cancer Res 62:3264-3270
-
(2002)
Cancer Res
, vol.62
, pp. 3264-3270
-
-
El-Hizawi, S.1
Lagowski, J.P.2
Kulesz-Martin, M.3
Albor, A.4
-
16
-
-
0037218849
-
P21(CIP1) Controls proliferating cell nuclear antigen level in adult cardiomyocytes
-
Engel FB, Hauck L, Boehm M, Nabel EG, Dietz R, von Harsdorf R (2003) p21(CIP1) Controls proliferating cell nuclear antigen level in adult cardiomyocytes. Mol Cell Biol 23:555-565
-
(2003)
Mol Cell Biol
, vol.23
, pp. 555-565
-
-
Engel, F.B.1
Hauck, L.2
Boehm, M.3
Nabel, E.G.4
Dietz, R.5
Von Harsdorf, R.6
-
17
-
-
0034034949
-
Human SP-C gene sequences that confer lung epithelium-specific expression in transgenic mice
-
Glasser SW, Burhans MS, Eszterhas SK, Bruno MD, Korfhagen TR (2000) Human SP-C gene sequences that confer lung epithelium-specific expression in transgenic mice. Am J Physiol Lung Cell Mol Physiol 278:L933-L945
-
(2000)
Am J Physiol Lung Cell Mol Physiol
, vol.278
-
-
Glasser, S.W.1
Burhans, M.S.2
Eszterhas, S.K.3
Bruno, M.D.4
Korfhagen, T.R.5
-
19
-
-
0029906260
-
The 273rd codon mutants of p53 show growth modulation activities not correlated with p53-specific transactivation activity
-
Kawamura M, Yamashita T, Segawa K, Kaneuchi M, Shindoh M, Fujinaga K (1996) The 273rd codon mutants of p53 show growth modulation activities not correlated with p53-specific transactivation activity. Oncogene 12:2361-2367
-
(1996)
Oncogene
, vol.12
, pp. 2361-2367
-
-
Kawamura, M.1
Yamashita, T.2
Segawa, K.3
Kaneuchi, M.4
Shindoh, M.5
Fujinaga, K.6
-
20
-
-
0026510193
-
Oncogenic forms of p53 inhibit p53-regulated gene expression
-
Kern SE, Pietelpol JA, Thiagalingam S, Seymour A, Kinzler KW, Vogelstein B (1992) Oncogenic forms of p53 inhibit p53-regulated gene expression. Science 256:827-830
-
(1992)
Science
, vol.256
, pp. 827-830
-
-
Kern, S.E.1
Pietelpol, J.A.2
Thiagalingam, S.3
Seymour, A.4
Kinzler, K.W.5
Vogelstein, B.6
-
21
-
-
0029972806
-
P53: Puzzle and paradigm
-
Ko JL, Prives C (1996) p53: puzzle and paradigm. Genes Dev 10:1054-1072
-
(1996)
Genes Dev
, vol.10
, pp. 1054-1072
-
-
Ko, J.L.1
Prives, C.2
-
22
-
-
0025078491
-
Cis-acting sequences from a human surfactant protein gene confer pulmonary-specific gene expression in transgenic mice
-
Korfhagen TR, Glasser SW, Wert SE, Bruno MD, Daugherty CC, McNeish JD, Stock JL, Potter SS, Whitsett JA (1990) Cis-acting sequences from a human surfactant protein gene confer pulmonary-specific gene expression in transgenic mice. Proc Natl Acad Sci USA 87:6122-6126
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 6122-6126
-
-
Korfhagen, T.R.1
Glasser, S.W.2
Wert, S.E.3
Bruno, M.D.4
Daugherty, C.C.5
McNeish, J.D.6
Stock, J.L.7
Potter, S.S.8
Whitsett, J.A.9
-
24
-
-
0026060757
-
Tumor suppressor p53: Analysis of wild-type and mutant p53 complexes
-
Milner J, Medcalf EA, Cook AC (1991) Tumor suppressor p53: analysis of wild-type and mutant p53 complexes. Mol Cell Biol 11:12-19
-
(1991)
Mol Cell Biol
, vol.11
, pp. 12-19
-
-
Milner, J.1
Medcalf, E.A.2
Cook, A.C.3
-
25
-
-
0026543204
-
P53 gene mutations in non-small-cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical features
-
Mitsudomi T, Steinberg SM, Nau MM, Carbone D, D'Amico D, Bodner S, Oie HK, Linnoila RI, Mulshine JL, Minna JD (1992) p53 gene mutations in non-small-cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical features. Oncogene 7:171-180
-
(1992)
Oncogene
, vol.7
, pp. 171-180
-
-
Mitsudomi, T.1
Steinberg, S.M.2
Nau, M.M.3
Carbone, D.4
D'Amico, D.5
Bodner, S.6
Oie, H.K.7
Linnoila, R.I.8
Mulshine, J.L.9
Minna, J.D.10
-
26
-
-
10944236962
-
Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome
-
Olive KP, Tuveson DA, Ruhe ZC, Yin B, Willis NA, Bronson RT, Crowley D, Jacks T (2004) Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome. Cell 119:847-860
-
(2004)
Cell
, vol.119
, pp. 847-860
-
-
Olive, K.P.1
Tuveson, D.A.2
Ruhe, Z.C.3
Yin, B.4
Willis, N.A.5
Bronson, R.T.6
Crowley, D.7
Jacks, T.8
-
27
-
-
0036258111
-
The IARC TP53 Database: New online mutation analysis and recommendations to users
-
Olivier M, Eeles R, Hollstein M, Khan MA, Harris CC, Hainaut P (2002) The IARC TP53 Database: new online mutation analysis and recommendations to users. Hum Mutat 19:607-614
-
(2002)
Hum Mutat
, vol.19
, pp. 607-614
-
-
Olivier, M.1
Eeles, R.2
Hollstein, M.3
Khan, M.A.4
Harris, C.C.5
Hainaut, P.6
-
28
-
-
0028298935
-
Transactivational and DNA binding abilities of endogenous p53 in p53 mutant cell lines
-
Park DJ, Nakamura H, Chumakov AM, Said JW, Miller CW, Chen DL, Koeffler HP (1994) Transactivational and DNA binding abilities of endogenous p53 in p53 mutant cell lines. Oncogene 9:1899-1906
-
(1994)
Oncogene
, vol.9
, pp. 1899-1906
-
-
Park, D.J.1
Nakamura, H.2
Chumakov, A.M.3
Said, J.W.4
Miller, C.W.5
Chen, D.L.6
Koeffler, H.P.7
-
29
-
-
0034769436
-
Proliferating cell nuclear antigen (PCNA): Ringmaster of the genome
-
Paunesku T, Mittal S, Protic M, Oryhon J, Korolev SV, Joachimiak A, Woloschak GE (2001) Proliferating cell nuclear antigen (PCNA): ringmaster of the genome. Int J Radiat Biol 77:1007-1021
-
(2001)
Int J Radiat Biol
, vol.77
, pp. 1007-1021
-
-
Paunesku, T.1
Mittal, S.2
Protic, M.3
Oryhon, J.4
Korolev, S.V.5
Joachimiak, A.6
Woloschak, G.E.7
-
30
-
-
0034671945
-
Oncogenic mutations of the p53 tumor suppressor: The demons of the guardian of the genome
-
Sigal A, Rotter V (2000) Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome. Cancer Res 60:6788-6793
-
(2000)
Cancer Res
, vol.60
, pp. 6788-6793
-
-
Sigal, A.1
Rotter, V.2
-
31
-
-
0034595638
-
Characterization of MyD118, Gadd45, and proliferating cell nuclear antigen (PCNA) interacting domains. PCNA impedes MyD118 and Gadd45-mediated negative growth control
-
Vairapandi M, Azam N, Balliet AG, Hoffman B, Liebermann DA (2000) Characterization of MyD118, Gadd45, and proliferating cell nuclear antigen (PCNA) interacting domains. PCNA impedes MyD118 AND Gadd45-mediated negative growth control. J Biol Chem 275:16810-16819
-
(2000)
J Biol Chem
, vol.275
, pp. 16810-16819
-
-
Vairapandi, M.1
Azam, N.2
Balliet, A.G.3
Hoffman, B.4
Liebermann, D.A.5
-
32
-
-
0034122591
-
Gain-of-function mutations in the tumor suppressor gene p53
-
van Oijen MG, Slootweg PJ (2000) Gain-of-function mutations in the tumor suppressor gene p53. Clin Cancer Res 6:2138-2145
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2138-2145
-
-
Van Oijen, M.G.1
Slootweg, P.J.2
-
33
-
-
0028915813
-
Alternatively spliced forms in the carboxy-terminal domain of the p53 protein regulate its ability to promote annealing of complementary single strands of nucleic acids
-
Wu L, Bayle JH, Elenbaas B, Pavletich NP, Levine AJ (1995) Alternatively spliced forms in the carboxy-terminal domain of the p53 protein regulate its ability to promote annealing of complementary single strands of nucleic acids. Mol Cell Biol 15:497-504
-
(1995)
Mol Cell Biol
, vol.15
, pp. 497-504
-
-
Wu, L.1
Bayle, J.H.2
Elenbaas, B.3
Pavletich, N.P.4
Levine, A.J.5
-
34
-
-
0027717617
-
P21 is a universal inhibitor of cyclin kinases
-
Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R, Beach D (1993) p21 is a universal inhibitor of cyclin kinases. Nature 366:701-704
-
(1993)
Nature
, vol.366
, pp. 701-704
-
-
Xiong, Y.1
Hannon, G.J.2
Zhang, H.3
Casso, D.4
Kobayashi, R.5
Beach, D.6
-
35
-
-
0032947176
-
P53-mediated regulation of proliferating cell nuclear antigen expression in cells exposed to ionizing radiation
-
Xu J, Morris GF (1999) p53-mediated regulation of proliferating cell nuclear antigen expression in cells exposed to ionizing radiation. Mol Cell Biol 19:12-20
-
(1999)
Mol Cell Biol
, vol.19
, pp. 12-20
-
-
Xu, J.1
Morris, G.F.2
-
36
-
-
0027275854
-
Novel DNA binding of p53 mutants and their role in transcriptional activation
-
Zhang W, Funk WD, Wright WE, Shay JW, Deisseroth AB (1993) Novel DNA binding of p53 mutants and their role in transcriptional activation. Oncogene 8:2555-2559
-
(1993)
Oncogene
, vol.8
, pp. 2555-2559
-
-
Zhang, W.1
Funk, W.D.2
Wright, W.E.3
Shay, J.W.4
Deisseroth, A.B.5
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