메뉴 건너뛰기




Volumn 14, Issue 6, 2014, Pages s33-s37

Spatial and temporal cancer evolution: causes and consequences of tumour diversity

Author keywords

Cancer; evolution; heterogeneity; resistance

Indexed keywords

CHEMISTRY; DISEASE COURSE; DNA SEQUENCE; DRUG RESISTANCE; GENETICS; HUMAN; MOLECULAR EVOLUTION; NEOPLASM; ONCOGENESIS AND MALIGNANT TRANSFORMATION; PATHOLOGY; PHYLOGENY; SPATIOTEMPORAL ANALYSIS;

EID: 84938366051     PISSN: 14702118     EISSN: 14734893     Source Type: Journal    
DOI: 10.7861/clinmedicine.14-6-s33     Document Type: Article
Times cited : (26)

References (30)
  • 1
    • 0017250977 scopus 로고
    • DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA
    • Stehelin, D, Varmus, HE, Bishop, JM, et al. DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature 260 (1976), 170–173 10.1038/260170a0.
    • (1976) Nature , vol.260 , pp. 170-173
    • Stehelin, D.1    Varmus, H.E.2    Bishop, J.M.3
  • 2
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Nowell, PC, The clonal evolution of tumor cell populations. Science 194 (1976), 23–28 10.1126/science.959840.
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1
  • 3
    • 84880507665 scopus 로고    scopus 로고
    • Mutational heterogeneity in cancer and the search for new cancer-associated genes
    • Lawrence, MS, Stojanov, P, Polak, P, et al. Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature 499 (2013), 214–218 10.1038/nature12213.
    • (2013) Nature , vol.499 , pp. 214-218
    • Lawrence, M.S.1    Stojanov, P.2    Polak, P.3
  • 4
    • 0033388315 scopus 로고    scopus 로고
    • Genetic instability and darwinian selection in tumours
    • Cahill, DP, Kinzler, KW, Vogelstein, B, et al. Genetic instability and darwinian selection in tumours. Trends Cell Biol 9 (1999), 57–60 10.1016/S0962-8924(99)01661-X.
    • (1999) Trends Cell Biol , vol.9 , pp. 57-60
    • Cahill, D.P.1    Kinzler, K.W.2    Vogelstein, B.3
  • 5
    • 78049380554 scopus 로고    scopus 로고
    • The patterns and dynamics of genomic instability in metastatic pancreatic cancer
    • Campbell, PJ, Yachida, S, Mudie, LJ, et al. The patterns and dynamics of genomic instability in metastatic pancreatic cancer. Nature 467 (2010), 1109–1113 10.1038/nature09460.
    • (2010) Nature , vol.467 , pp. 1109-1113
    • Campbell, P.J.1    Yachida, S.2    Mudie, L.J.3
  • 6
    • 78751644099 scopus 로고    scopus 로고
    • Genetic variegation of clonal architecture and propagating cells in leukaemia
    • Anderson, K, Lutz, C, van Delft, FW, et al. Genetic variegation of clonal architecture and propagating cells in leukaemia. Nature 469 (2011), 356–361 10.1038/nature09650.
    • (2011) Nature , vol.469 , pp. 356-361
    • Anderson, K.1    Lutz, C.2    van Delft, F.W.3
  • 7
    • 79953766940 scopus 로고    scopus 로고
    • Tumour evolution inferred by single-cell sequencing
    • Navin, N, Kendall, J, Troge, J, et al. Tumour evolution inferred by single-cell sequencing. Nature 472 (2011), 90–94 10.1038/nature09807.
    • (2011) Nature , vol.472 , pp. 90-94
    • Navin, N.1    Kendall, J.2    Troge, J.3
  • 8
    • 84891102589 scopus 로고    scopus 로고
    • Mutational signatures: the patterns of somatic mutations hidden in cancer genomes
    • Alexandrov, LB, Stratton, MR, Mutational signatures: the patterns of somatic mutations hidden in cancer genomes. Curr Opin Genet Dev 24C (2014), 52–60 10.1016/j.gde.2013.11.014.
    • (2014) Curr Opin Genet Dev , vol.24C , pp. 52-60
    • Alexandrov, L.B.1    Stratton, M.R.2
  • 9
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan, D, Weinberg, RA, Hallmarks of cancer: the next generation. Cell 144 (2011), 646–674 10.1016/j.cell.2011.02.013.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 10
    • 84884365015 scopus 로고    scopus 로고
    • The causes and consequences of genetic heterogeneity in cancer evolution
    • Burrell, RA, McGranahan, N, Bartek, J, et al. The causes and consequences of genetic heterogeneity in cancer evolution. Nature 501 (2013), 338–345 10.1038/nature12625.
    • (2013) Nature , vol.501 , pp. 338-345
    • Burrell, R.A.1    McGranahan, N.2    Bartek, J.3
  • 11
    • 84863922124 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of human colon and rectal cancer
    • The Cancer Genome Atlas. Comprehensive molecular characterization of human colon and rectal cancer. Nature 487 (2012), 330–337 10.1038/nature11252.
    • (2012) Nature , vol.487 , pp. 330-337
  • 12
    • 75149188170 scopus 로고    scopus 로고
    • Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes
    • Dalgliesh, GL, Furge, K, Greenman, C, et al. Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes. Nature 463 (2010), 360–363 10.1038/nature08672.
    • (2010) Nature , vol.463 , pp. 360-363
    • Dalgliesh, G.L.1    Furge, K.2    Greenman, C.3
  • 13
    • 79251635938 scopus 로고    scopus 로고
    • Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
    • Varela, I, Tarpey, P, Raine, K, et al. Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature 469 (2011), 539–542 10.1038/nature09639.
    • (2011) Nature , vol.469 , pp. 539-542
    • Varela, I.1    Tarpey, P.2    Raine, K.3
  • 14
    • 84896711553 scopus 로고    scopus 로고
    • Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution
    • Dewhurst, SM, McGranahan, N, Burrell, RA, et al. Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution. Cancer Discov 4 (2014), 175–185 10.1158/2159-8290.CD-13-0285.
    • (2014) Cancer Discov , vol.4 , pp. 175-185
    • Dewhurst, S.M.1    McGranahan, N.2    Burrell, R.A.3
  • 15
    • 33748286796 scopus 로고    scopus 로고
    • A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
    • Carter, SL, Eklund, AC, Kohane, IS, et al. A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers. Nat Genet 38 (2006), 1043–1048 10.1038/ng1861.
    • (2006) Nat Genet , vol.38 , pp. 1043-1048
    • Carter, S.L.1    Eklund, A.C.2    Kohane, I.S.3
  • 16
    • 84861851519 scopus 로고    scopus 로고
    • Cancer chromosomal instability: therapeutic and diagnostic challenges
    • McGranahan, N, Burrell, RA, Endesfelder, D, et al. Cancer chromosomal instability: therapeutic and diagnostic challenges. EMBO Rep 13 (2012), 528–538 10.1038/embor.2012.61.
    • (2012) EMBO Rep , vol.13 , pp. 528-538
    • McGranahan, N.1    Burrell, R.A.2    Endesfelder, D.3
  • 17
    • 84875757638 scopus 로고    scopus 로고
    • Punctuated evolution of prostate cancer genomes
    • Baca, SC, Prandi, D, Lawrence, MS, et al. Punctuated evolution of prostate cancer genomes. Cell 153 (2013), 666–677 10.1016/j.cell.2013.03.021.
    • (2013) Cell , vol.153 , pp. 666-677
    • Baca, S.C.1    Prandi, D.2    Lawrence, M.S.3
  • 18
    • 78650959663 scopus 로고    scopus 로고
    • Massive genomic rearrangement acquired in a single catastrophic event during cancer development
    • Stephens, PJ, Greenman, CD, Fu, B, et al. Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 144 (2011), 27–40 10.1016/j.cell.2010.11.055.
    • (2011) Cell , vol.144 , pp. 27-40
    • Stephens, P.J.1    Greenman, C.D.2    Fu, B.3
  • 19
    • 84862776906 scopus 로고    scopus 로고
    • Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
    • Ding, L, Ley, TJ, Larson, DE, et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature 481 (2012), 506–510 10.1038/nature10738.
    • (2012) Nature , vol.481 , pp. 506-510
    • Ding, L.1    Ley, T.J.2    Larson, D.E.3
  • 20
    • 33646256145 scopus 로고    scopus 로고
    • A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy
    • Hunter, C, Smith, R, Cahill, DP, et al. A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy. Cancer Res 66 (2006), 3987–3991 10.1158/0008-5472.CAN-06-0127.
    • (2006) Cancer Res , vol.66 , pp. 3987-3991
    • Hunter, C.1    Smith, R.2    Cahill, D.P.3
  • 21
    • 84863393080 scopus 로고    scopus 로고
    • Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
    • Gerlinger, M, Rowan, AJ, Horswell, S, et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med 366 (2012), 883–892 10.1056/NEJMoa1113205.
    • (2012) N Engl J Med , vol.366 , pp. 883-892
    • Gerlinger, M.1    Rowan, A.J.2    Horswell, S.3
  • 22
    • 84895876130 scopus 로고    scopus 로고
    • Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
    • Gerlinger, M, Horswell, S, Larkin, J, et al. Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing. Nat Genet 46 (2014), 225–233 10.1038/ng.2891.
    • (2014) Nat Genet , vol.46 , pp. 225-233
    • Gerlinger, M.1    Horswell, S.2    Larkin, J.3
  • 23
    • 78049398107 scopus 로고    scopus 로고
    • Distant metastasis occurs late during the genetic evolution of pancreatic cancer
    • Yachida, S, Jones, S, Bozic, I, et al. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature 467 (2010), 1114–1117 10.1038/nature09515.
    • (2010) Nature , vol.467 , pp. 1114-1117
    • Yachida, S.1    Jones, S.2    Bozic, I.3
  • 24
    • 84863116159 scopus 로고    scopus 로고
    • Loss of human epidermal growth factor receptor 2 (HER2) expression in metastatic sites of HER2-overexpressing primary breast tumors
    • Niikura, N, Liu, J, Hayashi, N, et al. Loss of human epidermal growth factor receptor 2 (HER2) expression in metastatic sites of HER2-overexpressing primary breast tumors. J Clin Oncol 30 (2012), 593–599 10.1200/JCO.2010.33.8889.
    • (2012) J Clin Oncol , vol.30 , pp. 593-599
    • Niikura, N.1    Liu, J.2    Hayashi, N.3
  • 25
    • 84863011443 scopus 로고    scopus 로고
    • Pretreatment epidermal growth factor receptor (EGFR) T790M mutation predicts shorter EGFR tyrosine kinase inhibitor response duration in patients with non-small-cell lung cancer
    • Su, KY, Chen, HY, Li, KC, et al. Pretreatment epidermal growth factor receptor (EGFR) T790M mutation predicts shorter EGFR tyrosine kinase inhibitor response duration in patients with non-small-cell lung cancer. J Clin Oncol 30 (2012), 433–440 10.1200/JCO.2011.38.3224.
    • (2012) J Clin Oncol , vol.30 , pp. 433-440
    • Su, K.Y.1    Chen, H.Y.2    Li, K.C.3
  • 26
    • 84874102335 scopus 로고    scopus 로고
    • Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
    • Landau, DA, Carter, SL, Stojanov, P, et al. Evolution and impact of subclonal mutations in chronic lymphocytic leukemia. Cell 152 (2013), 714–726 10.1016/j.cell.2013.01.019.
    • (2013) Cell , vol.152 , pp. 714-726
    • Landau, D.A.1    Carter, S.L.2    Stojanov, P.3
  • 27
    • 73649123907 scopus 로고    scopus 로고
    • Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma -characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
    • Verhaak, RG, Hoadley, KA, Purdom, E, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma -characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17 (2010), 98–110 10.1016/j.ccr.2009.12.020.
    • (2010) Cancer Cell , vol.17 , pp. 98-110
    • Verhaak, R.G.1    Hoadley, K.A.2    Purdom, E.3
  • 28
    • 84874598318 scopus 로고    scopus 로고
    • Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
    • Sottoriva, A, Spiteri, I, Piccirillo, SG, et al. Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics. Proc Natl Acad Sci USA 110 (2013), 4009–4014 10.1073/pnas.1219747110.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 4009-4014
    • Sottoriva, A.1    Spiteri, I.2    Piccirillo, S.G.3
  • 29
    • 84902204035 scopus 로고    scopus 로고
    • Predictive performance of microarray gene signatures: impact of tumor heterogeneity and multiple mechanisms of drug resistance
    • in press
    • Ng, CK, Weigelt, B, A'Hern, R, et al. Predictive performance of microarray gene signatures: impact of tumor heterogeneity and multiple mechanisms of drug resistance. Cancer Res, 2014 in press.
    • (2014) Cancer Res
    • Ng, C.K.1    Weigelt, B.2    A'Hern, R.3
  • 30
    • 84856013431 scopus 로고    scopus 로고
    • Clonal evolution in cancer
    • Greaves, M, Maley, CC, Clonal evolution in cancer. Nature 481 (2012), 306–313 10.1038/nature10762.
    • (2012) Nature , vol.481 , pp. 306-313
    • Greaves, M.1    Maley, C.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.