Neutrophil elastase promotes myofibroblast differentiation in lung fibrosis

Journal of Leukocyte Biology

Volumn 98, Issue 2, 2015, Pages 143-152

  Gregory, Alyssa D ^a   Kliment, Corrine R ^a   Metz, Heather E ^a,b   Kim, Kyoung Hee ^b   Kargl, Julia ^b   Agostini, Brittani A ^a   Crum, Lauren T ^a   Oczypok, Elizabeth A ^a   Oury, Tim A ^a   Houghton, A McGarry ^b,c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Asbestos; Fibroblasts; IRS 1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; LEUKOCYTE ELASTASE; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; IN VITRO STUDY; LUNG FIBROBLAST; LUNG FIBROSIS; MOUSE; MYOFIBROBLAST; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; DISEASE MODEL; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; LUNG; LUNG EMPHYSEMA; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

MUS;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HUMANS; INSULIN RECEPTOR SUBSTRATE PROTEINS; LEUKOCYTE ELASTASE; LUNG; MICE; MYOFIBROBLASTS; NEUTROPHILS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PULMONARY EMPHYSEMA; PULMONARY FIBROSIS; SIGNAL TRANSDUCTION;

EID: 84938323703     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.3HI1014-493R     Document Type: Article

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