Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci

Nature Communications

Volumn 6, Issue , 2015, Pages

  Betz, Regina C ^a   Petukhova, Lynn ^b   Ripke, Stephan ^c,d   Huang, Hailiang ^c,d   Menelaou, Androniki ^e   Redler, Silke ^a   Becker, Tim ^a,f   Heilmann, Stefanie ^a   Yamany, Tarek ^b   Duvic, Madeliene ^g   Hordinsky, Maria ^h   Norris, David ⁱ   Price, Vera H ^j   MacKay Wiggan, Julian ^b   De Jong, Annemieke ^b   DeStefano, Gina M ^b   Moebus, Susanne ^k   Böhm, Markus ^l   Blume Peytavi, Ulrike ^m   Wolff, Hans ⁿ   Lutz, Gerhard ^o   Kruse, Roland ^p   Bian, Li ^b   Amos, Christopher I ^q   Lee, Annette ^r   Gregersen, Peter K ^r   Blaumeiser, Bettina ^s   Altshuler, David ^c,d   Clynes, Raphael ^b   De Bakker, Paul I W ^e   Nöthen, Markus M ^a   Daly, Mark J ^c,d   Christiano, Angela M ^b   more..

^a UNIVERSITY OF BONN   (Germany)

^b Howard Hughes Medical Institute   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^e UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^f GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^g UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^h UNIVERSITY OF MINNESOTA   (United States)

ⁱ UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^j UNIVERSITY OF CALIFORNIA   (United States)

^k UNIVERSITY OF DUISBURG ESSEN   (Germany)

^l UNIVERSITY OF MÜNSTER   (Germany)

^m CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

ⁿ LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^o Dermatological Practice   (Germany)

^p Private Dermatology Practice   (Germany)

^q DARTMOUTH MEDICAL SCHOOL   (United States)

^r FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^s UNIVERSITY OF ANTWERP   (Belgium)

more..

Author keywords

[No Author keywords available]

Indexed keywords

HLA DR ANTIGEN; JANUS KINASE; TRANSFORMING GROWTH FACTOR BETA; APOPTOSIS REGULATORY PROTEIN; ATAXIN 2; ATXN2 PROTEIN, HUMAN; BCL2L11 PROTEIN, HUMAN; BCL2L11 PROTEIN, MOUSE; BIM PROTEIN; HLA ANTIGEN; LNK PROTEIN, HUMAN; LRRC32 PROTEIN, HUMAN; MEMBRANE PROTEIN; ONCOPROTEIN; PROTEIN;

ANTIGEN; APOPTOSIS; BLOOD; DISABILITY; ETIOLOGY; GENE EXPRESSION; GENOME; IMMUNE RESPONSE; META-ANALYSIS; PROTEIN;

ALOPECIA AREATA; APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; AUTOPHAGY; GENE LOCUS; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; HAIR FOLLICLE; HLA SYSTEM; HUMAN; IMMUNOCOMPETENT CELL; MAJOR HISTOCOMPATIBILITY COMPLEX; META ANALYSIS; PHENOTYPE; ALLELE; ANIMAL; CASE CONTROL STUDY; DNA MICROARRAY; FEMALE; FLUORESCENCE MICROSCOPY; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; MALE; METABOLISM; MOUSE; PRINCIPAL COMPONENT ANALYSIS; PROTEIN CONFORMATION; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN;

ALLELES; ALOPECIA AREATA; ANIMALS; APOPTOSIS REGULATORY PROTEINS; ATAXIN-2; BCL-2-LIKE PROTEIN 11; CASE-CONTROL STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HLA ANTIGENS; HUMANS; MALE; MEMBRANE PROTEINS; MICE; MICROSCOPY, FLUORESCENCE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PRINCIPAL COMPONENT ANALYSIS; PROTEIN CONFORMATION; PROTEINS; PROTO-ONCOGENE PROTEINS; SKIN;

EID: 84938251791     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6966     Document Type: Article

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