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Volumn 407, Issue 3, 2015, Pages 699-717

The many facets of Raman spectroscopy for biomedical analysis

Author keywords

Clinical biomedical analysis; IR spectroscopy; Raman spectroscopy; Spectroscopy instrumentation

Indexed keywords

BACTERIA; CELLS; COHERENT SCATTERING; CYTOLOGY; IMAGE ACQUISITION; INFRARED SPECTROSCOPY; SPECTROSCOPY; SPECTRUM ANALYSIS; STIMULATED RAMAN SCATTERING; SURFACE SCATTERING; TISSUE;

EID: 84938243415     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-014-8311-9     Document Type: Review
Times cited : (160)

References (119)
  • 1
    • 84865585238 scopus 로고    scopus 로고
    • Raman and coherent anti-Stokes Raman scattering microspectroscopy for biomedical applications
    • Krafft C, Dietzek B, Schmitt M, Popp J (2012) Raman and coherent anti-Stokes Raman scattering microspectroscopy for biomedical applications. J Biomed Opt 17(4):040801
    • (2012) J Biomed Opt , vol.17 , Issue.4 , pp. 040801
    • Krafft, C.1    Dietzek, B.2    Schmitt, M.3    Popp, J.4
  • 2
    • 77951640513 scopus 로고    scopus 로고
    • Laser tricks without labels
    • 1:CAS:528:DC%2BC3cXjvFKqu7w%3D
    • Baker M (2010) Laser tricks without labels. Nat Methods 7(4):261-266. doi: 10.1038/nmeth0410-261
    • (2010) Nat Methods , vol.7 , Issue.4 , pp. 261-266
    • Baker, M.1
  • 3
    • 84882338791 scopus 로고    scopus 로고
    • Methods and applications of Raman microspectroscopy to single-cell analysis
    • 1:CAS:528:DC%2BC3sXht1Gnu7jN
    • Schie IW, Huser T (2013) Methods and applications of Raman microspectroscopy to single-cell analysis. Appl Spectrosc 67(8):813-828. doi: 10.1366/12-06971
    • (2013) Appl Spectrosc , vol.67 , Issue.8 , pp. 813-828
    • Schie, I.W.1    Huser, T.2
  • 4
    • 84879291555 scopus 로고    scopus 로고
    • Label-free analysis of cellular biochemistry by Raman spectroscopy and microscopy
    • Schie IW, Huser T (2013) Label-free analysis of cellular biochemistry by Raman spectroscopy and microscopy. Compr Physiol 3(2):941-956. doi: 10.1002/cphy.c120025
    • (2013) Compr Physiol , vol.3 , Issue.2 , pp. 941-956
    • Schie, I.W.1    Huser, T.2
  • 5
    • 84889632418 scopus 로고    scopus 로고
    • Accumulating advantages, reducing limitations: Multimodal nonlinear imaging in biomedical sciences - The synergy of multiple contrast mechanisms
    • Meyer T, Schmitt M, Dietzek B, Popp J (2013) Accumulating advantages, reducing limitations: multimodal nonlinear imaging in biomedical sciences - the synergy of multiple contrast mechanisms. J Biophotonics 6(11-12):887-904. doi: 10.1002/jbio.201300176
    • (2013) J Biophotonics , vol.6 , Issue.11-12 , pp. 887-904
    • Meyer, T.1    Schmitt, M.2    Dietzek, B.3    Popp, J.4
  • 6
    • 84891936627 scopus 로고    scopus 로고
    • Coherent anti-Stokes Raman scattering microscopy: Overcoming technical barriers for clinical translation
    • Tu H, Boppart SA (2014) Coherent anti-Stokes Raman scattering microscopy: overcoming technical barriers for clinical translation. J Biophotonics 7(1-2):9-22. doi: 10.1002/jbio.201300031
    • (2014) J Biophotonics , vol.7 , Issue.1-2 , pp. 9-22
    • Tu, H.1    Boppart, S.A.2
  • 7
    • 84875337336 scopus 로고    scopus 로고
    • Raman molecular imaging of cells and tissues: Towards functional diagnostic imaging without labeling
    • 1:CAS:528:DC%2BC3sXltlGrtb4%3D
    • Harada Y, Takamatsu T (2013) Raman molecular imaging of cells and tissues: towards functional diagnostic imaging without labeling. Curr Pharm Biotechnol 14(2):133-140
    • (2013) Curr Pharm Biotechnol , vol.14 , Issue.2 , pp. 133-140
    • Harada, Y.1    Takamatsu, T.2
  • 8
    • 84874571044 scopus 로고    scopus 로고
    • Raman spectroscopy in biomedicine - Non-invasive in vitro analysis of cells and extracellular matrix components in tissues
    • 1:CAS:528:DC%2BC38Xhs1ykt7jL
    • Brauchle E, Schenke-Layland K (2013) Raman spectroscopy in biomedicine - non-invasive in vitro analysis of cells and extracellular matrix components in tissues. Biotechnol J 8(3):288-297. doi: 10.1002/biot.201200163
    • (2013) Biotechnol J , vol.8 , Issue.3 , pp. 288-297
    • Brauchle, E.1    Schenke-Layland, K.2
  • 9
    • 67249092421 scopus 로고    scopus 로고
    • Raman and CARS microspectroscopy of cells and tissues
    • 1:CAS:528:DC%2BD1MXmsVSnu70%3D
    • Krafft C, Dietzek B, Popp J (2009) Raman and CARS microspectroscopy of cells and tissues. Analyst 134(6):1046-1057
    • (2009) Analyst , vol.134 , Issue.6 , pp. 1046-1057
    • Krafft, C.1    Dietzek, B.2    Popp, J.3
  • 10
    • 84878481768 scopus 로고    scopus 로고
    • Fiber optic probes for linear and nonlinear Raman applications: Current trend and future development
    • 1:CAS:528:DC%2BC3sXhsVahsrfN
    • Latka I, Dochow S, Krafft C, Dietzek B, Popp J (2013) Fiber optic probes for linear and nonlinear Raman applications: current trend and future development. Laser Photonics Rev 7(5):698-731
    • (2013) Laser Photonics Rev , vol.7 , Issue.5 , pp. 698-731
    • Latka, I.1    Dochow, S.2    Krafft, C.3    Dietzek, B.4    Popp, J.5
  • 11
    • 60849133023 scopus 로고    scopus 로고
    • Vibrational spectroscopy-a powerful tool for the rapid identification of microbial cells at the single-cell level
    • 1:STN:280:DC%2BD1M3ls1yrtg%3D%3D
    • Harz M, Rosch P, Popp J (2009) Vibrational spectroscopy-a powerful tool for the rapid identification of microbial cells at the single-cell level. Cytometry A 75(2):104-113. doi: 10.1002/cyto.a.20682
    • (2009) Cytometry A , vol.75 , Issue.2 , pp. 104-113
    • Harz, M.1    Rosch, P.2    Popp, J.3
  • 12
    • 77951630643 scopus 로고    scopus 로고
    • Shining light on the microbial world: The application of Raman microspectroscopy
    • A.I. Laskin S. Sariaslani G.M. Gadd (eds), Elsevier, San Diego
    • Huang WE, Li MQ, Jarvis RM, Goodacre R, Banwart SA (2010) Shining light on the microbial world: the application of Raman microspectroscopy. In: Laskin AI, Sariaslani S, Gadd GM (eds) Advances in applied microbiology, vol 70, Advances in applied microbiology. Elsevier, San Diego, pp 153-186. doi: 10.1016/s0065-2164(10)70005-8
    • (2010) Advances in Applied Microbiology , vol.70 , pp. 153-186
    • Huang, W.E.1    Li, M.Q.2    Jarvis, R.M.3    Goodacre, R.4    Banwart, S.A.5
  • 13
    • 65449155208 scopus 로고    scopus 로고
    • Chemical analysis in vivo and in vitro by Raman spectroscopy-from single cells to humans
    • 1:CAS:528:DC%2BD1MXlslWgsrY%3D
    • Wachsmann-Hogiu S, Weeks T, Huser T (2009) Chemical analysis in vivo and in vitro by Raman spectroscopy-from single cells to humans. Curr Opin Biotechnol 20(1):63-73
    • (2009) Curr Opin Biotechnol , vol.20 , Issue.1 , pp. 63-73
    • Wachsmann-Hogiu, S.1    Weeks, T.2    Huser, T.3
  • 14
    • 84871993028 scopus 로고    scopus 로고
    • Recent advances in laser tweezers Raman spectroscopy (LTRS) for label-free analysis of single cells
    • 1:CAS:528:DC%2BC3sXjsFyntA%3D%3D
    • Chan JW (2013) Recent advances in laser tweezers Raman spectroscopy (LTRS) for label-free analysis of single cells. J Biophotonics 6(1):36-48
    • (2013) J Biophotonics , vol.6 , Issue.1 , pp. 36-48
    • Chan, J.W.1
  • 15
    • 84856443106 scopus 로고    scopus 로고
    • Single cell Raman spectroscopy for cell sorting and imaging
    • 1:CAS:528:DC%2BC38XhvFartbw%3D
    • Li MQ, Xu J, Romero-Gonzalez M, Banwart SA, Huang WE (2012) Single cell Raman spectroscopy for cell sorting and imaging. Curr Opin Biotechnol 23(1):56-63. doi: 10.1016/j.copbio.2011.11.019
    • (2012) Curr Opin Biotechnol , vol.23 , Issue.1 , pp. 56-63
    • Li, M.Q.1    Xu, J.2    Romero-Gonzalez, M.3    Banwart, S.A.4    Huang, W.E.5
  • 17
    • 61349099647 scopus 로고    scopus 로고
    • Disease recognition by infrared and Raman spectroscopy
    • 1:CAS:528:DC%2BD1MXktlKlsLc%3D
    • Krafft C, Steiner G, Beleites C, Salzer R (2009) Disease recognition by infrared and Raman spectroscopy. J Biophotonics 2(1-2):13-28. doi: 10.1002/jbio.200810024
    • (2009) J Biophotonics , vol.2 , Issue.1-2 , pp. 13-28
    • Krafft, C.1    Steiner, G.2    Beleites, C.3    Salzer, R.4
  • 20
    • 77955494684 scopus 로고    scopus 로고
    • Raman Spectroscopy and related techniques in biomedicine
    • Downes A, Elfick A (2010) Raman Spectroscopy and related techniques in biomedicine. Sensors 10(3):1871-1889. doi: 10.3390/s100301871
    • (2010) Sensors , vol.10 , Issue.3 , pp. 1871-1889
    • Downes, A.1    Elfick, A.2
  • 21
    • 33846854208 scopus 로고    scopus 로고
    • In vivo estimation of stratum corneum thickness from water concentration profiles obtained with Raman spectroscopy
    • Egawa M, Hirao T, Takahashi M (2007) In vivo estimation of stratum corneum thickness from water concentration profiles obtained with Raman spectroscopy. Acta Derm Venereol 87(1):4-8. doi: 10.2340/00015555-0183
    • (2007) Acta Derm Venereol , vol.87 , Issue.1 , pp. 4-8
    • Egawa, M.1    Hirao, T.2    Takahashi, M.3
  • 22
    • 84871975116 scopus 로고    scopus 로고
    • Recent advances in the development of Raman spectroscopy for deep non-invasive medical diagnosis
    • 1:CAS:528:DC%2BC3sXjsFymsg%3D%3D
    • Matousek P, Stone N (2013) Recent advances in the development of Raman spectroscopy for deep non-invasive medical diagnosis. J Biophotonics 6(1):7-19. doi: 10.1002/jbio.201200141
    • (2013) J Biophotonics , vol.6 , Issue.1 , pp. 7-19
    • Matousek, P.1    Stone, N.2
  • 23
    • 84862646339 scopus 로고    scopus 로고
    • Diagnostic applications of Raman spectroscopy
    • 1:CAS:528:DC%2BC38XptVKlsbc%3D
    • Tu Q, Chang C (2012) Diagnostic applications of Raman spectroscopy. Nanomedicine 8(5):545-558. doi: 10.1016/j.nano.2011.09.013
    • (2012) Nanomedicine , vol.8 , Issue.5 , pp. 545-558
    • Tu, Q.1    Chang, C.2
  • 24
    • 84865578517 scopus 로고    scopus 로고
    • Multiplex optical sensing with surface-enhanced Raman scattering: A critical review
    • 1:CAS:528:DC%2BC38Xht1Glur3M
    • Rodriguez-Lorenzo L, Fabris L, Alvarez-Puebla RA (2012) Multiplex optical sensing with surface-enhanced Raman scattering: a critical review. Anal Chim Acta 745:10-23. doi: 10.1016/j.aca.2012.08.003
    • (2012) Anal Chim Acta , vol.745 , pp. 10-23
    • Rodriguez-Lorenzo, L.1    Fabris, L.2    Alvarez-Puebla, R.A.3
  • 25
    • 84875520828 scopus 로고    scopus 로고
    • Surface-enhanced Raman scattering in cancer detection and imaging
    • 1:CAS:528:DC%2BC3sXis1Onsr4%3D
    • Vendrell M, Maiti KK, Dhaliwal K, Chang YT (2013) Surface-enhanced Raman scattering in cancer detection and imaging. Trends Biotechnol 31(4):249-257. doi: 10.1016/j.tibtech.2013.01.013
    • (2013) Trends Biotechnol , vol.31 , Issue.4 , pp. 249-257
    • Vendrell, M.1    Maiti, K.K.2    Dhaliwal, K.3    Chang, Y.T.4
  • 26
    • 84880154922 scopus 로고    scopus 로고
    • Microfluidics and Raman microscopy: Current applications and future challenges
    • 1:CAS:528:DC%2BC3sXptFWjtbo%3D
    • Chrimes AF, Khoshmanesh K, Stoddart PR, Mitchell A, Kalantar-zadeh K (2013) Microfluidics and Raman microscopy: current applications and future challenges. Chem Soc Rev 42(13):5880-5906. doi: 10.1039/c3cs35515b
    • (2013) Chem Soc Rev , vol.42 , Issue.13 , pp. 5880-5906
    • Chrimes, A.F.1    Khoshmanesh, K.2    Stoddart, P.R.3    Mitchell, A.4    Kalantar-Zadeh, K.5
  • 27
    • 84873824984 scopus 로고    scopus 로고
    • Current status of matrix-assisted laser desorption ionisation-time of flight mass spectrometry in the clinical microbiology laboratory
    • 1:CAS:528:DC%2BC38XhvVynsrnK
    • Kok J, Chen SCA, Dwyer DE, Iredell JR (2013) Current status of matrix-assisted laser desorption ionisation-time of flight mass spectrometry in the clinical microbiology laboratory. Pathology 45(1):4-17. doi: 10.1097/PAT.0b013e32835be408
    • (2013) Pathology , vol.45 , Issue.1 , pp. 4-17
    • Kok, J.1    Chen, S.C.A.2    Dwyer, D.E.3    Iredell, J.R.4
  • 29
    • 84886921145 scopus 로고    scopus 로고
    • Culture independent Raman spectroscopic identification of urinary tract infection pathogens: A proof of principle study
    • 1:CAS:528:DC%2BC3sXhsVSisb%2FM
    • Kloss S, Kampe B, Sachse S, Rosch P, Straube E, Pfister W, Kiehntopf M, Popp J (2013) Culture independent Raman spectroscopic identification of urinary tract infection pathogens: a proof of principle study. Anal Chem 85(20):9610-9616. doi: 10.1021/ac401806f
    • (2013) Anal Chem , vol.85 , Issue.20 , pp. 9610-9616
    • Kloss, S.1    Kampe, B.2    Sachse, S.3    Rosch, P.4    Straube, E.5    Pfister, W.6    Kiehntopf, M.7    Popp, J.8
  • 30
    • 84869442998 scopus 로고    scopus 로고
    • Identification of Bacillus anthracis via Raman spectroscopy and chemometric approaches
    • 1:STN:280:DC%2BC3s%2FotFertg%3D%3D
    • Stockel S, Meisel S, Elschner M, Rosch P, Popp J (2012) Identification of Bacillus anthracis via Raman spectroscopy and chemometric approaches. Anal Chem 84(22):9873-9880. doi: 10.1021/ac302250t
    • (2012) Anal Chem , vol.84 , Issue.22 , pp. 9873-9880
    • Stockel, S.1    Meisel, S.2    Elschner, M.3    Rosch, P.4    Popp, J.5
  • 31
    • 84861501408 scopus 로고    scopus 로고
    • Raman spectroscopic detection of anthrax endospores in powder samples
    • 1:STN:280:DC%2BC38rlt1Kisg%3D%3D
    • Stockel S, Meisel S, Elschner M, Rosch P, Popp J (2012) Raman spectroscopic detection of anthrax endospores in powder samples. Angew Chem Int Ed 51(22):5339-5342. doi: 10.1002/anie.201201266
    • (2012) Angew Chem Int Ed , vol.51 , Issue.22 , pp. 5339-5342
    • Stockel, S.1    Meisel, S.2    Elschner, M.3    Rosch, P.4    Popp, J.5
  • 34
    • 84874090559 scopus 로고    scopus 로고
    • Detecting and tracking nosocomial methicillin-resistant Staphylococcus aureus using a microfluidic SERS biosensor
    • 1:CAS:528:DC%2BC3sXhtFWlurk%3D
    • Lu XN, Samuelson DR, Xu YH, Zhang HW, Wang S, Rasco BA, Xu J, Konkel ME (2013) Detecting and tracking nosocomial methicillin-resistant Staphylococcus aureus using a microfluidic SERS biosensor. Anal Chem 85(4):2320-2327. doi: 10.1021/ac303279u
    • (2013) Anal Chem , vol.85 , Issue.4 , pp. 2320-2327
    • Lu, X.N.1    Samuelson, D.R.2    Xu, Y.H.3    Zhang, H.W.4    Wang, S.5    Rasco, B.A.6    Xu, J.7    Konkel, M.E.8
  • 35
    • 84893476306 scopus 로고    scopus 로고
    • Simultaneous detection and quantification of three bacterial meningitis pathogens by SERS
    • 1:CAS:528:DC%2BC2cXhs1Ortbk%3D
    • Gracie K, Correa E, Mabbott S, Dougan JA, Graham D, Goodacre R, Faulds K (2014) Simultaneous detection and quantification of three bacterial meningitis pathogens by SERS. Chem Sci 5(3):1030-1040. doi: 10.1039/c3sc52875h
    • (2014) Chem Sci , vol.5 , Issue.3 , pp. 1030-1040
    • Gracie, K.1    Correa, E.2    Mabbott, S.3    Dougan, J.A.4    Graham, D.5    Goodacre, R.6    Faulds, K.7
  • 36
    • 78349288080 scopus 로고    scopus 로고
    • Towards detection and identification of circulating tumour cells using Raman spectroscopy
    • 1:CAS:528:DC%2BC3cXhsVejsr%2FN
    • Neugebauer U, Bocklitz T, Clement JH, Krafft C, Popp J (2010) Towards detection and identification of circulating tumour cells using Raman spectroscopy. Analyst 135(12):3178-3182
    • (2010) Analyst , vol.135 , Issue.12 , pp. 3178-3182
    • Neugebauer, U.1    Bocklitz, T.2    Clement, J.H.3    Krafft, C.4    Popp, J.5
  • 37
    • 84881611664 scopus 로고    scopus 로고
    • Raman spectroscopy and partial least squares analysis in discrimination of peripheral cells affected by Huntington's disease
    • 1:CAS:528:DC%2BC3sXhtVCrtLfK
    • Muratore M (2013) Raman spectroscopy and partial least squares analysis in discrimination of peripheral cells affected by Huntington's disease. Anal Chim Acta 793:1-10. doi: 10.1016/j.aca.2013.06.012
    • (2013) Anal Chim Acta , vol.793 , pp. 1-10
    • Muratore, M.1
  • 38
    • 84881137428 scopus 로고    scopus 로고
    • Identification of different subsets of lung cells using Raman microspectroscopy and whole cell nucleus isolation
    • 1:CAS:528:DC%2BC3sXhtFOltbvL
    • Pijanka JK, Stone N, Rutter AV, Forsyth N, Sockalingum GD, Yang Y, Sule-Suso J (2013) Identification of different subsets of lung cells using Raman microspectroscopy and whole cell nucleus isolation. Analyst 138(17):5052-5058. doi: 10.1039/c3an00968h
    • (2013) Analyst , vol.138 , Issue.17 , pp. 5052-5058
    • Pijanka, J.K.1    Stone, N.2    Rutter, A.V.3    Forsyth, N.4    Sockalingum, G.D.5    Yang, Y.6    Sule-Suso, J.7
  • 39
    • 84873579478 scopus 로고    scopus 로고
    • Detection and identification of cancerous murine fibroblasts, transformed by murine sarcoma virus in culture, using Raman spectroscopy and advanced statistical methods
    • 1:CAS:528:DC%2BC3sXitFChsL8%3D
    • Salman A, Shufan E, Zeiri L, Huleihel M (2013) Detection and identification of cancerous murine fibroblasts, transformed by murine sarcoma virus in culture, using Raman spectroscopy and advanced statistical methods. Biochim Biophys Acta 1830(3):2720-2727. doi: 10.1016/j.bbagen.2012.11.023
    • (2013) Biochim Biophys Acta , vol.1830 , Issue.3 , pp. 2720-2727
    • Salman, A.1    Shufan, E.2    Zeiri, L.3    Huleihel, M.4
  • 40
    • 84906948948 scopus 로고    scopus 로고
    • Rapid and label-free identification of normal spermatozoa based on image analysis and micro-Raman spectroscopy
    • Huang Z, Chen G, Chen X, Wang J, Chen J, Lu P, Chen R (2013) Rapid and label-free identification of normal spermatozoa based on image analysis and micro-Raman spectroscopy. J Biophotonics 7(9):671-675. doi: 10.1002/jbio.201300003
    • (2013) J Biophotonics , vol.7 , Issue.9 , pp. 671-675
    • Huang, Z.1    Chen, G.2    Chen, X.3    Wang, J.4    Chen, J.5    Lu, P.6    Chen, R.7
  • 41
    • 84873254701 scopus 로고    scopus 로고
    • Non-invasive identification of proteoglycans and chondrocyte differentiation state by Raman microspectroscopy
    • 1:CAS:528:DC%2BC3sXhvFGrt78%3D
    • Pudlas M, Brauchle E, Klein TJ, Hutmacher DW, Schenke-Layland K (2013) Non-invasive identification of proteoglycans and chondrocyte differentiation state by Raman microspectroscopy. J Biophotonics 6(2):205-211. doi: 10.1002/jbio.201200064
    • (2013) J Biophotonics , vol.6 , Issue.2 , pp. 205-211
    • Pudlas, M.1    Brauchle, E.2    Klein, T.J.3    Hutmacher, D.W.4    Schenke-Layland, K.5
  • 42
    • 84872053713 scopus 로고    scopus 로고
    • Subcellular spectroscopic markers, topography and nanomechanics of human lung cancer and breast cancer cells examined by combined confocal Raman microspectroscopy and atomic force microscopy
    • 1:CAS:528:DC%2BC3sXhslGluw%3D%3D
    • McEwen GD, Wu Y, Tang M, Qi X, Xiao Z, Baker SM, Yu T, Gilbertson TA, DeWald DB, Zhou A (2013) Subcellular spectroscopic markers, topography and nanomechanics of human lung cancer and breast cancer cells examined by combined confocal Raman microspectroscopy and atomic force microscopy. Analyst 138(3):787-797. doi: 10.1039/c2an36359c
    • (2013) Analyst , vol.138 , Issue.3 , pp. 787-797
    • McEwen, G.D.1    Wu, Y.2    Tang, M.3    Qi, X.4    Xiao, Z.5    Baker, S.M.6    Yu, T.7    Gilbertson, T.A.8    Dewald, D.B.9    Zhou, A.10
  • 43
    • 84864694332 scopus 로고    scopus 로고
    • Identification of abnormal stem cells using Raman spectroscopy
    • 1:CAS:528:DC%2BC38XhtFOhtrrN
    • Harkness L, Novikov SM, Beermann J, Bozhevolnyi SI, Kassem M (2012) Identification of abnormal stem cells using Raman spectroscopy. Stem Cells Dev 21(12):2152-2159. doi: 10.1089/scd.2011.0600
    • (2012) Stem Cells Dev , vol.21 , Issue.12 , pp. 2152-2159
    • Harkness, L.1    Novikov, S.M.2    Beermann, J.3    Bozhevolnyi, S.I.4    Kassem, M.5
  • 45
    • 80455176616 scopus 로고    scopus 로고
    • Toward label-free Raman-activated cell sorting of cardiomyocytes derived from human embryonic stem cells
    • Pascut FC, Goh HT, George V, Denning C, Notingher I (2011) Toward label-free Raman-activated cell sorting of cardiomyocytes derived from human embryonic stem cells. J Biomed Opt 16(4):045002. doi: 10.1117/1.3570302
    • (2011) J Biomed Opt , vol.16 , Issue.4 , pp. 045002
    • Pascut, F.C.1    Goh, H.T.2    George, V.3    Denning, C.4    Notingher, I.5
  • 46
    • 84874527729 scopus 로고    scopus 로고
    • Quantitative analysis of the redox states of cytochromes in a living L929 (NCTC) cell by resonance Raman microspectroscopy
    • 1:CAS:528:DC%2BC3sXjsFektr8%3D
    • Kakita M, Okuno M, Hamaguchi HO (2013) Quantitative analysis of the redox states of cytochromes in a living L929 (NCTC) cell by resonance Raman microspectroscopy. J Biophotonics 6(3):256-259. doi: 10.1002/jbio.201200042
    • (2013) J Biophotonics , vol.6 , Issue.3 , pp. 256-259
    • Kakita, M.1    Okuno, M.2    Hamaguchi, H.O.3
  • 47
    • 0025873479 scopus 로고
    • Laser irradiation and Raman spectroscopy of single living cells and chromosomes: Sample degradation occurs with 514.5 nm but not with 660 nm laser light
    • 1:STN:280:DyaK3MzgtFWqsA%3D%3D
    • Puppels GJ, Olminkhof JH, Segers-Nolten GM, Otto C, De Mul FF, Greve J (1991) Laser irradiation and Raman spectroscopy of single living cells and chromosomes: sample degradation occurs with 514.5 nm but not with 660 nm laser light. Exp Cell Res 195(2):361-367
    • (1991) Exp Cell Res , vol.195 , Issue.2 , pp. 361-367
    • Puppels, G.J.1    Olminkhof, J.H.2    Segers-Nolten, G.M.3    Otto, C.4    De Mul, F.F.5    Greve, J.6
  • 49
    • 33745686170 scopus 로고    scopus 로고
    • Studies on stress-induced changes at the subcellular level by Raman microspectroscopic mapping
    • 1:CAS:528:DC%2BD28XktlKmtrk%3D
    • Krafft C, Knetschke T, Funk RH, Salzer R (2006) Studies on stress-induced changes at the subcellular level by Raman microspectroscopic mapping. Anal Chem 78(13):4424-4429
    • (2006) Anal Chem , vol.78 , Issue.13 , pp. 4424-4429
    • Krafft, C.1    Knetschke, T.2    Funk, R.H.3    Salzer, R.4
  • 50
    • 77957340867 scopus 로고    scopus 로고
    • Identification and differentiation of single cells from peripheral blood by Raman spectroscopic imaging
    • 1:CAS:528:DC%2BC3cXhtFKktb%2FM
    • Neugebauer U, Clement JH, Bocklitz T, Krafft C, Popp J (2010) Identification and differentiation of single cells from peripheral blood by Raman spectroscopic imaging. J Biophotonics 3(8-9):579-587
    • (2010) J Biophotonics , vol.3 , Issue.8-9 , pp. 579-587
    • Neugebauer, U.1    Clement, J.H.2    Bocklitz, T.3    Krafft, C.4    Popp, J.5
  • 51
    • 84869414363 scopus 로고    scopus 로고
    • Noninvasive imaging of intracellular lipid metabolism in macrophages by Raman microscopy in combination with stable isotopic labeling
    • Matthaus C, Krafft C, Dietzek B, Brehm BR, Lorkowski S, Popp J (2012) Noninvasive imaging of intracellular lipid metabolism in macrophages by Raman microscopy in combination with stable isotopic labeling. Anal Chem 84(20):8549-8556. doi: 10.1021/ac3012347
    • (2012) Anal Chem , vol.84 , Issue.20 , pp. 8549-8556
    • Matthaus, C.1    Krafft, C.2    Dietzek, B.3    Brehm, B.R.4    Lorkowski, S.5    Popp, J.6
  • 52
    • 0042977275 scopus 로고    scopus 로고
    • Raman microspectroscopy: A comparison of point, line, and wide-field imaging methodologies
    • Schlücker S, Schaeberle MD, Huffman SW, Levin IW (2003) Raman microspectroscopy: a comparison of point, line, and wide-field imaging methodologies. Anal Chem 75(16):4312-4318
    • (2003) Anal Chem , vol.75 , Issue.16 , pp. 4312-4318
    • Schlücker, S.1    Schaeberle, M.D.2    Huffman, S.W.3    Levin, I.W.4
  • 53
    • 84875524370 scopus 로고    scopus 로고
    • Raman and SERS microscopy for molecular imaging of live cells
    • 1:CAS:528:DC%2BC3sXjsFCls7Y%3D
    • Palonpon AF, Ando J, Yamakoshi H, Dodo K, Sodeoka M, Kawata S, Fujita K (2013) Raman and SERS microscopy for molecular imaging of live cells. Nat Protoc 8(4):677-692. doi: 10.1038/nprot.2013.030
    • (2013) Nat Protoc , vol.8 , Issue.4 , pp. 677-692
    • Palonpon, A.F.1    Ando, J.2    Yamakoshi, H.3    Dodo, K.4    Sodeoka, M.5    Kawata, S.6    Fujita, K.7
  • 54
    • 84928377187 scopus 로고    scopus 로고
    • Complexity of fatty acid distribution inside human macrophages on single cell level using Raman micro-spectroscopy
    • 1:CAS:528:DC%2BC2cXhtVSltrbK
    • Stiebing C, Matthäus C, Krafft C, Keller AA, Weber K, Lorkowski S, Popp J (2014) Complexity of fatty acid distribution inside human macrophages on single cell level using Raman micro-spectroscopy. Anal Bioanal Chem 406(27):7037-7046. doi: 10.1007/s00216-014-7927-0
    • (2014) Anal Bioanal Chem , vol.406 , Issue.27 , pp. 7037-7046
    • Stiebing, C.1    Matthäus, C.2    Krafft, C.3    Keller, A.A.4    Weber, K.5    Lorkowski, S.6    Popp, J.7
  • 55
    • 84885015322 scopus 로고    scopus 로고
    • Direct comparison of fatty acid ratios in single cellular lipid droplets as determined by comparative Raman spectroscopy and gas chromatography
    • 1:CAS:528:DC%2BC3sXhsFehu7jM
    • Schie IW, Nolte L, Pedersen TL, Smith Z, Wu J, Yahiatene I, Newman JW, Huser T (2013) Direct comparison of fatty acid ratios in single cellular lipid droplets as determined by comparative Raman spectroscopy and gas chromatography. Analyst 138(21):6662-6670. doi: 10.1039/c3an00970j
    • (2013) Analyst , vol.138 , Issue.21 , pp. 6662-6670
    • Schie, I.W.1    Nolte, L.2    Pedersen, T.L.3    Smith, Z.4    Wu, J.5    Yahiatene, I.6    Newman, J.W.7    Huser, T.8
  • 56
    • 46149090832 scopus 로고    scopus 로고
    • An integrated optofluidic platform for Raman-activated cell sorting
    • 1:CAS:528:DC%2BD1cXnvFehsLk%3D
    • Lau AY, Lee LP, Chan JW (2008) An integrated optofluidic platform for Raman-activated cell sorting. Lab Chip 8(7):1116-1120
    • (2008) Lab Chip , vol.8 , Issue.7 , pp. 1116-1120
    • Lau, A.Y.1    Lee, L.P.2    Chan, J.W.3
  • 58
    • 79953175999 scopus 로고    scopus 로고
    • Tumour cell identification by means of Raman spectroscopy in combination with optical traps and microfluidic environments
    • 1:CAS:528:DC%2BC3MXktVSisLs%3D
    • Dochow S, Krafft C, Neugebauer U, Bocklitz T, Henkel T, Mayer G, Albert J, Popp J (2011) Tumour cell identification by means of Raman spectroscopy in combination with optical traps and microfluidic environments. Lab Chip 11(8):1484-1490
    • (2011) Lab Chip , vol.11 , Issue.8 , pp. 1484-1490
    • Dochow, S.1    Krafft, C.2    Neugebauer, U.3    Bocklitz, T.4    Henkel, T.5    Mayer, G.6    Albert, J.7    Popp, J.8
  • 59
    • 84878410186 scopus 로고    scopus 로고
    • Quartz microfluidic chip for tumour cell identification by Raman spectroscopy in combination with optical traps
    • 1:CAS:528:DC%2BC3sXhvFWnur4%3D
    • Dochow S, Beleites C, Henkel T, Mayer G, Albert J, Clement J, Krafft C, Popp J (2013) Quartz microfluidic chip for tumour cell identification by Raman spectroscopy in combination with optical traps. Anal Bioanal Chem 405:2743-2746
    • (2013) Anal Bioanal Chem , vol.405 , pp. 2743-2746
    • Dochow, S.1    Beleites, C.2    Henkel, T.3    Mayer, G.4    Albert, J.5    Clement, J.6    Krafft, C.7    Popp, J.8
  • 61
    • 84861094498 scopus 로고    scopus 로고
    • Preparation and characterization of multicore SERS labels by controlled aggregation of gold nanoparticles
    • 1:CAS:528:DC%2BC38XmvVKnurc%3D
    • Freitag I, Neugebauer U, Csaki A, Fritzsche W, Krafft C, Popp J (2012) Preparation and characterization of multicore SERS labels by controlled aggregation of gold nanoparticles. Vib Spectrosc 60:79-84
    • (2012) Vib Spectrosc , vol.60 , pp. 79-84
    • Freitag, I.1    Neugebauer, U.2    Csaki, A.3    Fritzsche, W.4    Krafft, C.5    Popp, J.6
  • 62
    • 68749083557 scopus 로고    scopus 로고
    • Generalized approach to SERS-active nanomaterials via controlled nanoparticle linking, polymer encapsulation, and small-molecule infusion
    • 1:CAS:528:DC%2BD1MXot1eiu7c%3D
    • Braun GB, Lee SJ, Laurence T, Fera N, Fabris L, Bazan GC, Moskovits M, Reich NO (2009) Generalized approach to SERS-active nanomaterials via controlled nanoparticle linking, polymer encapsulation, and small-molecule infusion. J Phys Chem C 113(31):13622-13629. doi: 10.1021/jp903399p
    • (2009) J Phys Chem C , vol.113 , Issue.31 , pp. 13622-13629
    • Braun, G.B.1    Lee, S.J.2    Laurence, T.3    Fera, N.4    Fabris, L.5    Bazan, G.C.6    Moskovits, M.7    Reich, N.O.8
  • 63
    • 79952209996 scopus 로고    scopus 로고
    • Detection of circulating tumor cells in human peripheral blood using surface-enhanced Raman scattering nanoparticles
    • 1:CAS:528:DC%2BC3MXisFCgu7o%3D
    • Wang X, Qian X, Beitler JJ, Chen ZG, Khuri FR, Lewis MM, Shin HJC, Nie S, Shin DM (2011) Detection of circulating tumor cells in human peripheral blood using surface-enhanced Raman scattering nanoparticles. Cancer Res 71(5):1526-1532. doi: 10.1158/0008-5472.can-10-3069
    • (2011) Cancer Res , vol.71 , Issue.5 , pp. 1526-1532
    • Wang, X.1    Qian, X.2    Beitler, J.J.3    Chen, Z.G.4    Khuri, F.R.5    Lewis, M.M.6    Shin, H.J.C.7    Nie, S.8    Shin, D.M.9
  • 64
    • 60349119849 scopus 로고    scopus 로고
    • Surface-enhanced Raman scattering imaging of HER2 cancer markers overexpressed in single MCF7 cells using antibody conjugated hollow gold nanospheres
    • 1:CAS:528:DC%2BD1MXit1Oksrw%3D
    • Lee S, Chon H, Lee M, Choo J, Shin SY, Lee YH, Rhyu IJ, Son SW, Oh CH (2009) Surface-enhanced Raman scattering imaging of HER2 cancer markers overexpressed in single MCF7 cells using antibody conjugated hollow gold nanospheres. Biosens Bioelectron 24(7):2260-2263. doi: 10.1016/j.bios.2008.10.018
    • (2009) Biosens Bioelectron , vol.24 , Issue.7 , pp. 2260-2263
    • Lee, S.1    Chon, H.2    Lee, M.3    Choo, J.4    Shin, S.Y.5    Lee, Y.H.6    Rhyu, I.J.7    Son, S.W.8    Oh, C.H.9
  • 67
    • 77649090526 scopus 로고    scopus 로고
    • Bioinspired nanocorals with decoupled cellular targeting and sensing functionality
    • 1:CAS:528:DC%2BC3cXislKlsro%3D
    • Wu LY, Ross BM, Hong S, Lee LP (2010) Bioinspired nanocorals with decoupled cellular targeting and sensing functionality. Small 6(4):503-507. doi: 10.1002/smll.200901604
    • (2010) Small , vol.6 , Issue.4 , pp. 503-507
    • Wu, L.Y.1    Ross, B.M.2    Hong, S.3    Lee, L.P.4
  • 68
    • 67749106305 scopus 로고    scopus 로고
    • Surface-enhanced Raman scattering tags for rapid and homogeneous detection of circulating tumor cells in the presence of human whole blood
    • 1:CAS:528:DC%2BD1cXhsVOjsrfF
    • Sha MY, Xu H, Natan MJ, Cromer R (2008) Surface-enhanced Raman scattering tags for rapid and homogeneous detection of circulating tumor cells in the presence of human whole blood. J Am Chem Soc 130(51):17214-17215. doi: 10.1021/ja804494m
    • (2008) J Am Chem Soc , vol.130 , Issue.51 , pp. 17214-17215
    • Sha, M.Y.1    Xu, H.2    Natan, M.J.3    Cromer, R.4
  • 69
    • 84888372429 scopus 로고    scopus 로고
    • Quintuple-modality (SERS-MRI-CT-TPL-PTT) plasmonic nanoprobe for theranostics
    • 1:CAS:528:DC%2BC3sXhvVejtbrI
    • Liu Y, Chang Z, Yuan HK, Fales AM, Vo-Dinh T (2013) Quintuple-modality (SERS-MRI-CT-TPL-PTT) plasmonic nanoprobe for theranostics. Nanoscale 5(24):12126-12131. doi: 10.1039/c3nr03762b
    • (2013) Nanoscale , vol.5 , Issue.24 , pp. 12126-12131
    • Liu, Y.1    Chang, Z.2    Yuan, H.K.3    Fales, A.M.4    Vo-Dinh, T.5
  • 70
    • 80053629266 scopus 로고    scopus 로고
    • Quantitative ratiometric discrimination between noncancerous and cancerous prostate cells based on neuropilin-1 overexpression
    • 1:CAS:528:DC%2BC3MXhtlWksrvE
    • Pallaoro A, Braun GB, Moskovits M (2011) Quantitative ratiometric discrimination between noncancerous and cancerous prostate cells based on neuropilin-1 overexpression. Proc Natl Acad Sci U S A 108(40):16559-16564. doi: 10.1073/pnas.1109490108
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.40 , pp. 16559-16564
    • Pallaoro, A.1    Braun, G.B.2    Moskovits, M.3
  • 71
    • 67650064945 scopus 로고    scopus 로고
    • SERS microscopy: Nanoparticle probes and biomedical applications
    • 1:CAS:528:DC%2BD1MXptVGhurw%3D
    • Schluecker S (2009) SERS microscopy: nanoparticle probes and biomedical applications. ChemPhysChem 10(9-10):1344-1354. doi: 10.1002/cphc.200900119
    • (2009) ChemPhysChem , vol.10 , Issue.9-10 , pp. 1344-1354
    • Schluecker, S.1
  • 72
    • 0036500712 scopus 로고    scopus 로고
    • Simple multiplex genotyping by surface-enhanced resonance Raman scattering
    • 1:CAS:528:DC%2BD38XnvVGgsQ%3D%3D
    • Graham D, Mallinder BJ, Whitcombe D, Watson ND, Smith WE (2002) Simple multiplex genotyping by surface-enhanced resonance Raman scattering. Anal Chem 74(5):1069-1074. doi: 10.1021/ac0155456
    • (2002) Anal Chem , vol.74 , Issue.5 , pp. 1069-1074
    • Graham, D.1    Mallinder, B.J.2    Whitcombe, D.3    Watson, N.D.4    Smith, W.E.5
  • 74
    • 84894191479 scopus 로고    scopus 로고
    • Actively targeted in vivo multiplex detection of intrinsic cancer biomarkers using biocompatible SERS nanotags
    • Dinish US, Balasundaram G, Chang YT, Olivo M (2014) Actively targeted in vivo multiplex detection of intrinsic cancer biomarkers using biocompatible SERS nanotags. Sci Rep 4:4075. doi: 10.1038/srep04075
    • (2014) Sci Rep , vol.4 , pp. 4075
    • Dinish, U.S.1    Balasundaram, G.2    Chang, Y.T.3    Olivo, M.4
  • 75
    • 84882987612 scopus 로고    scopus 로고
    • Rapid and sensitive phenotypic marker detection on breast cancer cells using surface-enhanced Raman scattering (SERS) imaging
    • 1:CAS:528:DC%2BC3sXhsFGqsLzP
    • Lee S, Chon H, Lee J, Ko J, Chung BH, Lim DW, Choo J (2014) Rapid and sensitive phenotypic marker detection on breast cancer cells using surface-enhanced Raman scattering (SERS) imaging. Biosens Bioelectron 51:238-243. doi: 10.1016/j.bios.2013.07.063
    • (2014) Biosens Bioelectron , vol.51 , pp. 238-243
    • Lee, S.1    Chon, H.2    Lee, J.3    Ko, J.4    Chung, B.H.5    Lim, D.W.6    Choo, J.7
  • 76
    • 84865597500 scopus 로고    scopus 로고
    • Single cell analysis using surface enhanced Raman scattering (SERS) tags
    • 1:CAS:528:DC%2BC38XlvFynsLc%3D
    • Nolan JP, Duggan E, Liu E, Condello D, Dave I, Stoner SA (2012) Single cell analysis using surface enhanced Raman scattering (SERS) tags. Methods 57(3):272-279. doi: 10.1016/j.ymeth.2012.03.024
    • (2012) Methods , vol.57 , Issue.3 , pp. 272-279
    • Nolan, J.P.1    Duggan, E.2    Liu, E.3    Condello, D.4    Dave, I.5    Stoner, S.A.6
  • 77
    • 84873630708 scopus 로고    scopus 로고
    • Surface-enhanced Raman scattering dye-labeled au nanoparticles for triplexed detection of leukemia and lymphoma cells and SERS flow cytometry
    • 1:CAS:528:DC%2BC3sXktFSnug%3D%3D
    • MacLaughlin CM, Mullaithilaga N, Yang GS, Ip SY, Wang C, Walker GC (2013) Surface-enhanced Raman scattering dye-labeled au nanoparticles for triplexed detection of leukemia and lymphoma cells and SERS flow cytometry. Langmuir 29(6):1908-1919. doi: 10.1021/la303931c
    • (2013) Langmuir , vol.29 , Issue.6 , pp. 1908-1919
    • MacLaughlin, C.M.1    Mullaithilaga, N.2    Yang, G.S.3    Ip, S.Y.4    Wang, C.5    Walker, G.C.6
  • 78
    • 84890387175 scopus 로고    scopus 로고
    • Discriminating neoplastic and normal brain tissues in vitro through Raman spectroscopy: A principal components analysis classification model
    • 1:CAS:528:DC%2BC3sXhvV2hsL3O
    • Aguiar RP, Silveira L, Falcao ET, Pacheco MTT, Zangaro RA, Pasqualucci CA (2013) Discriminating neoplastic and normal brain tissues in vitro through Raman spectroscopy: a principal components analysis classification model. Photomed Laser Surg 31(12):595-604. doi: 10.1089/pho.2012.3460
    • (2013) Photomed Laser Surg , vol.31 , Issue.12 , pp. 595-604
    • Aguiar, R.P.1    Silveira, L.2    Falcao, E.T.3    Pacheco, M.T.T.4    Zangaro, R.A.5    Pasqualucci, C.A.6
  • 79
    • 77956473213 scopus 로고    scopus 로고
    • Differentiating normal and basal cell carcinoma human skin tissues in vitro using dispersive Raman spectroscopy: A comparison between principal components analysis and simplified biochemical models
    • 1:CAS:528:DC%2BC3MXltleltw%3D%3D
    • Bodanese B, Silveira L, Albertini R, Zangaro RA, Pacheco MTT (2010) Differentiating normal and basal cell carcinoma human skin tissues in vitro using dispersive Raman spectroscopy: a comparison between principal components analysis and simplified biochemical models. Photomed Laser Surg 28:S119-S127. doi: 10.1089/pho.2009.2565
    • (2010) Photomed Laser Surg , vol.28 , pp. S119-S127
    • Bodanese, B.1    Silveira, L.2    Albertini, R.3    Zangaro, R.A.4    Pacheco, M.T.T.5
  • 81
    • 79955965484 scopus 로고    scopus 로고
    • Evaluation of linear discriminant analysis for automated Raman histological mapping of esophageal high-grade dysplasia
    • Hutchings J, Kendall C, Shepherd N, Barr H, Stone N (2010) Evaluation of linear discriminant analysis for automated Raman histological mapping of esophageal high-grade dysplasia. J Biomed Opt 15(6):066015. doi: 10.1117/1.3512244
    • (2010) J Biomed Opt , vol.15 , Issue.6 , pp. 066015
    • Hutchings, J.1    Kendall, C.2    Shepherd, N.3    Barr, H.4    Stone, N.5
  • 82
    • 84884345259 scopus 로고    scopus 로고
    • Diagnosis of tumors during tissue-conserving surgery with integrated autofluorescence and Raman scattering microscopy
    • 1:CAS:528:DC%2BC3sXhsFOhsbnI
    • Kong K, Rowlands CJ, Varma S, Perkins W, Leach IH, Koloydenko AA, Williams HC, Notingher I (2013) Diagnosis of tumors during tissue-conserving surgery with integrated autofluorescence and Raman scattering microscopy. Proc Natl Acad Sci U S A 110(38):15189-15194. doi: 10.1073/pnas.1311289110
    • (2013) Proc Natl Acad Sci U S A , vol.110 , Issue.38 , pp. 15189-15194
    • Kong, K.1    Rowlands, C.J.2    Varma, S.3    Perkins, W.4    Leach, I.H.5    Koloydenko, A.A.6    Williams, H.C.7    Notingher, I.8
  • 84
    • 77951572390 scopus 로고    scopus 로고
    • Investigation of support vector machines and Raman spectroscopy for lymph node diagnostics
    • 1:CAS:528:DC%2BC3cXlt1Chs78%3D
    • Sattlecker M, Bessant C, Smith J, Stone N (2010) Investigation of support vector machines and Raman spectroscopy for lymph node diagnostics. Analyst 135(5):895-901
    • (2010) Analyst , vol.135 , Issue.5 , pp. 895-901
    • Sattlecker, M.1    Bessant, C.2    Smith, J.3    Stone, N.4
  • 85
  • 86
    • 84880043336 scopus 로고    scopus 로고
    • Method development: Raman spectroscopy-based histopathology of oral mucosa
    • 1:CAS:528:DC%2BC3sXnsFGmtLo%3D
    • Cals FLJ, Schut TCB, Koljenovic S, Puppels GJ, de Jong RJB (2013) Method development: Raman spectroscopy-based histopathology of oral mucosa. J Raman Spectrosc 44(7):963-972. doi: 10.1002/jrs.4318
    • (2013) J Raman Spectrosc , vol.44 , Issue.7 , pp. 963-972
    • Cals, F.L.J.1    Schut, T.C.B.2    Koljenovic, S.3    Puppels, G.J.4    De Jong, R.J.B.5
  • 87
    • 84898921838 scopus 로고    scopus 로고
    • Raman spectroscopy enables noninvasive biochemical characterization and identification of the stage of healing of a wound
    • 1:CAS:528:DC%2BC2cXivFWmsrg%3D
    • Jain R, Calderon D, Kierski PR, Schurr MJ, Czuprynski CJ, Murphy CJ, McAnulty JF, Abbott NL (2014) Raman spectroscopy enables noninvasive biochemical characterization and identification of the stage of healing of a wound. Anal Chem 86(8):3764-3772. doi: 10.1021/ac500513t
    • (2014) Anal Chem , vol.86 , Issue.8 , pp. 3764-3772
    • Jain, R.1    Calderon, D.2    Kierski, P.R.3    Schurr, M.J.4    Czuprynski, C.J.5    Murphy, C.J.6    McAnulty, J.F.7    Abbott, N.L.8
  • 88
    • 84875953880 scopus 로고    scopus 로고
    • Advances in optical biopsy-correlation of malignancy and cell density of primary brain tumors using Raman microspectroscopic imaging
    • 1:CAS:528:DC%2BC38XhsF2rsbnM
    • Krafft C, Belay B, Bergner N, Romeike BF, Reichart R, Kalff R, Popp J (2012) Advances in optical biopsy-correlation of malignancy and cell density of primary brain tumors using Raman microspectroscopic imaging. Analyst 137(23):5533-5537
    • (2012) Analyst , vol.137 , Issue.23 , pp. 5533-5537
    • Krafft, C.1    Belay, B.2    Bergner, N.3    Romeike, B.F.4    Reichart, R.5    Kalff, R.6    Popp, J.7
  • 89
    • 84861229379 scopus 로고    scopus 로고
    • Unsupervised unmixing of Raman microspectroscopic images for morphological analysis of non-dried brain tumor specimens
    • 1:CAS:528:DC%2BC38Xislygurc%3D
    • Bergner N, Krafft C, Geiger KD, Kirsch M, Schackert G, Popp J (2012) Unsupervised unmixing of Raman microspectroscopic images for morphological analysis of non-dried brain tumor specimens. Anal Bioanal Chem 403(3):719-725
    • (2012) Anal Bioanal Chem , vol.403 , Issue.3 , pp. 719-725
    • Bergner, N.1    Krafft, C.2    Geiger, K.D.3    Kirsch, M.4    Schackert, G.5    Popp, J.6
  • 90
    • 84893653133 scopus 로고    scopus 로고
    • Hyperspectral unmixing of Raman micro-images for assessment of morphological and chemical parameters in non-dried brain tumor specimens
    • 1:CAS:528:DC%2BC3sXht1CnsLbJ
    • Bergner N, Medyukhina A, Geiger KD, Kirsch M, Schackert G, Krafft C, Popp J (2013) Hyperspectral unmixing of Raman micro-images for assessment of morphological and chemical parameters in non-dried brain tumor specimens. Anal Bioanal Chem 405(27):8719-8728. doi: 10.1007/s00216-013-7257-7
    • (2013) Anal Bioanal Chem , vol.405 , Issue.27 , pp. 8719-8728
    • Bergner, N.1    Medyukhina, A.2    Geiger, K.D.3    Kirsch, M.4    Schackert, G.5    Krafft, C.6    Popp, J.7
  • 91
    • 44449136469 scopus 로고    scopus 로고
    • Noninvasive molecular imaging of small living subjects using Raman spectroscopy
    • 1:CAS:528:DC%2BD1cXltVyjtrk%3D
    • Keren S, Zavaleta C, Cheng Z, de la Zerda A, Gheysens O, Gambhir SS (2008) Noninvasive molecular imaging of small living subjects using Raman spectroscopy. Proc Natl Acad Sci U S A 105(15):5844-5849. doi: 10.1073/pnas.0710575105
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.15 , pp. 5844-5849
    • Keren, S.1    Zavaleta, C.2    Cheng, Z.3    De La Zerda, A.4    Gheysens, O.5    Gambhir, S.S.6
  • 92
    • 84870451724 scopus 로고    scopus 로고
    • Gold nanorods for ovarian cancer detection with photoacoustic imaging and resection guidance via Raman imaging in living mice
    • 1:CAS:528:DC%2BC38XhsFOntLfP
    • Jokerst JV, Cole AJ, Van de Sompel D, Gambhir SS (2012) Gold nanorods for ovarian cancer detection with photoacoustic imaging and resection guidance via Raman imaging in living mice. ACS Nano 6(11):10366-10377. doi: 10.1021/nn304347g
    • (2012) ACS Nano , vol.6 , Issue.11 , pp. 10366-10377
    • Jokerst, J.V.1    Cole, A.J.2    Van De Sompel, D.3    Gambhir, S.S.4
  • 93
    • 85013568574 scopus 로고    scopus 로고
    • Diagnosis and screening of cancer tissues by fiber-optic probe Raman spectroscopy
    • 1:CAS:528:DC%2BC3sXhtlSqu7zP
    • Krafft C, Dochow S, Latka I, Dietzek B, Popp J (2012) Diagnosis and screening of cancer tissues by fiber-optic probe Raman spectroscopy. Biomed Spectrosc Imaging 1:39-55
    • (2012) Biomed Spectrosc Imaging , vol.1 , pp. 39-55
    • Krafft, C.1    Dochow, S.2    Latka, I.3    Dietzek, B.4    Popp, J.5
  • 94
    • 84866402273 scopus 로고    scopus 로고
    • In vivo characterization of atherosclerotic plaque depositions by Raman-probe spectroscopy and in vitro CARS microscopic imaging on a rabbit model
    • Matthäus C, Dochow S, Bergner G, Lattermann A, Romeike B, Marple E, Krafft C, Dietzek B, Brehm B, Popp J (2012) In vivo characterization of atherosclerotic plaque depositions by Raman-probe spectroscopy and in vitro CARS microscopic imaging on a rabbit model. Anal Chem 84(18):7845-7851
    • (2012) Anal Chem , vol.84 , Issue.18 , pp. 7845-7851
    • Matthäus, C.1    Dochow, S.2    Bergner, G.3    Lattermann, A.4    Romeike, B.5    Marple, E.6    Krafft, C.7    Dietzek, B.8    Brehm, B.9    Popp, J.10
  • 95
    • 77957825221 scopus 로고    scopus 로고
    • Raman spectroscopic imaging for in vivo detection of cerebral brain metastases
    • 1:CAS:528:DC%2BC3cXhtVKhsbrI
    • Kirsch M, Schackert G, Salzer R, Krafft C (2010) Raman spectroscopic imaging for in vivo detection of cerebral brain metastases. Anal Bioanal Chem 398(4):1707-1713
    • (2010) Anal Bioanal Chem , vol.398 , Issue.4 , pp. 1707-1713
    • Kirsch, M.1    Schackert, G.2    Salzer, R.3    Krafft, C.4
  • 98
    • 84879628307 scopus 로고    scopus 로고
    • Near-infrared-excited confocal Raman spectroscopy advances in vivo diagnosis of cervical precancer
    • Duraipandian S, Zheng W, Ng J, Low JJH, Ilancheran A, Huang ZW (2013) Near-infrared-excited confocal Raman spectroscopy advances in vivo diagnosis of cervical precancer. J Biomed Opt 18(6):067007. doi: 10.1117/1.jbo.18.6.067007
    • (2013) J Biomed Opt , vol.18 , Issue.6 , pp. 067007
    • Duraipandian, S.1    Zheng, W.2    Ng, J.3    Low, J.J.H.4    Ilancheran, A.5    Huang, Z.W.6
  • 99
    • 79953101717 scopus 로고    scopus 로고
    • In vivo diagnosis of esophageal cancer using image-guided Raman endoscopy and biomolecular modeling
    • 1:CAS:528:DC%2BC3MXkvVylsb4%3D
    • Bergholt MS, Zheng W, Lin K, Ho KY, Teh M, Yeoh KG, So JBY, Huang Z (2011) In vivo diagnosis of esophageal cancer using image-guided Raman endoscopy and biomolecular modeling. Technol Cancer Res Treat 10(2):103-112
    • (2011) Technol Cancer Res Treat , vol.10 , Issue.2 , pp. 103-112
    • Bergholt, M.S.1    Zheng, W.2    Lin, K.3    Ho, K.Y.4    Teh, M.5    Yeoh, K.G.6    So, J.B.Y.7    Huang, Z.8
  • 101
    • 84887965467 scopus 로고    scopus 로고
    • High-sensitivity, real-time, ratiometric imaging of surface-enhanced Raman scattering nanoparticles with a clinically translatable Raman endoscope device
    • Garai E, Sensarn S, Zavaleta CL, Van de Sompel D, Loewke NO, Mandella MJ, Gambhir SS, Contag CH (2013) High-sensitivity, real-time, ratiometric imaging of surface-enhanced Raman scattering nanoparticles with a clinically translatable Raman endoscope device. J Biomed Opt 18(9):096008. doi: 10.1117/1.jbo.18.9.096008
    • (2013) J Biomed Opt , vol.18 , Issue.9 , pp. 096008
    • Garai, E.1    Sensarn, S.2    Zavaleta, C.L.3    Van De Sompel, D.4    Loewke, N.O.5    Mandella, M.J.6    Gambhir, S.S.7    Contag, C.H.8
  • 103
    • 84880677216 scopus 로고    scopus 로고
    • Widefield quantitative multiplex surface enhanced Raman scattering imaging in vivo
    • McVeigh PZ, Mallia RJ, Veilleux I, Wilson BC (2013) Widefield quantitative multiplex surface enhanced Raman scattering imaging in vivo. J Biomed Opt 18(4). doi: 10.1117/1.jbo.18.4.046011
    • (2013) J Biomed Opt , vol.18 , Issue.4
    • McVeigh, P.Z.1    Mallia, R.J.2    Veilleux, I.3    Wilson, B.C.4
  • 104
    • 84908432332 scopus 로고    scopus 로고
    • Using surface-enhanced Raman scattering nanoparticles and a hand-held Raman scanner
    • 1:CAS:528:DC%2BC2cXht12gtb7N
    • Karabeber H, Huang R, Iacono P, Samii JM, Pitter K, Holland EC, Kircher MF (2014) Using surface-enhanced Raman scattering nanoparticles and a hand-held Raman scanner. ACS Nano 8(10):9755-9766. doi: 10.1021/nn503948b
    • (2014) ACS Nano , vol.8 , Issue.10 , pp. 9755-9766
    • Karabeber, H.1    Huang, R.2    Iacono, P.3    Samii, J.M.4    Pitter, K.5    Holland, E.C.6    Kircher, M.F.7
  • 107
    • 84868699374 scopus 로고    scopus 로고
    • Towards automated segmentation of cells and cell nuclei in nonlinear optical microscopy
    • Medyukhina A, Meyer T, Schmitt M, Romeike BF, Dietzek B, Popp J (2012) Towards automated segmentation of cells and cell nuclei in nonlinear optical microscopy. J Biophotonics 5(11-12):878-888
    • (2012) J Biophotonics , vol.5 , Issue.11-12 , pp. 878-888
    • Medyukhina, A.1    Meyer, T.2    Schmitt, M.3    Romeike, B.F.4    Dietzek, B.5    Popp, J.6
  • 108
    • 84886893976 scopus 로고    scopus 로고
    • Automated seeding-based nuclei segmentation in nonlinear optical microscopy
    • Medyukhina A, Meyer T, Heuke S, Vogler N, Dietzek B, Popp J (2013) Automated seeding-based nuclei segmentation in nonlinear optical microscopy. Appl Opt 52(28):6979-6994. doi: 10.1364/ao.52.006979
    • (2013) Appl Opt , vol.52 , Issue.28 , pp. 6979-6994
    • Medyukhina, A.1    Meyer, T.2    Heuke, S.3    Vogler, N.4    Dietzek, B.5    Popp, J.6
  • 109
  • 113
    • 84857269288 scopus 로고    scopus 로고
    • Chemoselective imaging of mouse brain tissue via multiplex CARS microscopy
    • Pohling C, Buckup T, Pagenstecher A, Motzkus M (2011) Chemoselective imaging of mouse brain tissue via multiplex CARS microscopy. Biomed Opt Express 2(8):2110-2116
    • (2011) Biomed Opt Express , vol.2 , Issue.8 , pp. 2110-2116
    • Pohling, C.1    Buckup, T.2    Pagenstecher, A.3    Motzkus, M.4
  • 115
    • 77952531766 scopus 로고    scopus 로고
    • Multiplex coherent anti-Stokes Raman spectroscopy images intact atheromatous lesions and concomitantly identifies distinct chemical profiles of atherosclerotic lipids
    • 1:CAS:528:DC%2BC3cXmtlaktb4%3D
    • Kim SH, Lee ES, Lee JY, Lee BS, Park JE, Moon DW (2010) Multiplex coherent anti-Stokes Raman spectroscopy images intact atheromatous lesions and concomitantly identifies distinct chemical profiles of atherosclerotic lipids. Circ Res 106(8):1332-U1358. doi: 10.1161/circresaha.109.208678
    • (2010) Circ Res , vol.106 , Issue.8 , pp. 1332-U1358
    • Kim, S.H.1    Lee, E.S.2    Lee, J.Y.3    Lee, B.S.4    Park, J.E.5    Moon, D.W.6
  • 116
    • 84891911824 scopus 로고    scopus 로고
    • Characterization of collagen and cholesterol deposition in atherosclerotic arterial tissue using non-linear microscopy
    • 1:CAS:528:DC%2BC2cXnt1ahsQ%3D%3D
    • Cicchi R, Matthaus C, Meyer T, Lattermann A, Dietzek B, Brehm BR, Popp J, Pavone FS (2014) Characterization of collagen and cholesterol deposition in atherosclerotic arterial tissue using non-linear microscopy. J Biophotonics 7(1-2):135-143. doi: 10.1002/jbio.201300055
    • (2014) J Biophotonics , vol.7 , Issue.1-2 , pp. 135-143
    • Cicchi, R.1    Matthaus, C.2    Meyer, T.3    Lattermann, A.4    Dietzek, B.5    Brehm, B.R.6    Popp, J.7    Pavone, F.S.8
  • 119
    • 84857704547 scopus 로고    scopus 로고
    • On being second
    • (2012) On being second. Nat Methods 9(3):209-209
    • (2012) Nat Methods , vol.9 , Issue.3 , pp. 209-209


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