High-sensitivity, real-time, ratiometric imaging of surface-enhanced Raman scattering nanoparticles with a clinically translatable Raman endoscope device

Journal of Biomedical Optics

Volumn 18, Issue 9, 2013, Pages

  Garai, Ellis ^a,c   Sensarn, Steven ^b,c   Zavaleta, Cristina L ^b,c   Van De Sompel, Dominique ^b,c   Loewke, Nathan O ^a,c   Mandella, Michael J ^c   Gambhir, Sanjiv S ^b,c   Contag, Christopher H ^b,c  

^a Stanford University   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

endoscopy; optical design; optical devices; Raman effect; Raman spectroscopy; real time imaging

Indexed keywords

HARDWARE AND SOFTWARE; MODELING AND SIMULATING; RATIOMETRIC IMAGING TECHNIQUES; REALTIME IMAGING; RELATIVE CONCENTRATION; SURFACE ENHANCED RAMAN SCATTERING (SERS); TARGETED NANOPARTICLE; VARYING WORKING DISTANCE;

ENDOSCOPY; GRAPHICAL USER INTERFACES; IMAGING TECHNIQUES; OPTICAL DESIGN; OPTICAL DEVICES; RAMAN SCATTERING; RAMAN SPECTROSCOPY; SURFACE SCATTERING; WASHING;

NANOPARTICLES;

RAMAN SPECTROSCOPY; SCANNING; WASHING;

GLASS FIBER; NANOPARTICLE;

ALGORITHM; ARTICLE; CHEMISTRY; COLON; COMPUTER SIMULATION; ENDOSCOPE; EQUIPMENT; EQUIPMENT DESIGN; HUMAN; LIMIT OF DETECTION; METHODOLOGY; PRINCIPAL COMPONENT ANALYSIS; RAMAN SPECTROMETRY; SIGNAL PROCESSING; DEVICES; PROCEDURES;

ALGORITHMS; COLON; COMPUTER SIMULATION; ENDOSCOPES; EQUIPMENT DESIGN; HUMANS; LIMIT OF DETECTION; NANOPARTICLES; OPTICAL FIBERS; PRINCIPAL COMPONENT ANALYSIS; SIGNAL PROCESSING, COMPUTER-ASSISTED; SPECTRUM ANALYSIS, RAMAN;

EID: 84887965467     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.JBO.18.9.096008     Document Type: Article

References (47)

1. R. Siegel, D. Naishadham, and A. Jemal, "Cancer statistics, 2012,"
2. CA Cancer J. Clin. 62(1), 10-29 (2012).
3. A. Jemal et al., "Global cancer statistics," CA Cancer J. Clin. 61(2), 69-90 (2011).
4. R. M. Soetikno et al., "Prevalence of nonpolypoid (flat and depressed) colorectal neoplasms in asymptomatic and symptomatic adults," JAMA 299(9), 1027-1035 (2008). (Pubitemid 351347059)
5. J. V. Jokerst and S. S. Gambhir, "Molecular imaging with theranostic nanoparticles," Acc. Chem. Res. 44(10), 1050-1060 (2011).
6. C. L. Zavaleta, M. F. Kircher, and S. S. Gambhir, "Ramans effect on molecular imaging," J. Nucl. Med. 52(12), 1839-1844 (2011).
7. W. E. Doering et al., "SERS as a foundation for nanoscale, optically detected biological labels," Adv. Mater. 19(20), 3100-3108 (2007). (Pubitemid 350044443)
8. M. Fleischmann, P. J. Hendra, and A. J. McQuillan, "Raman spectra of pyridine adsorbed at a silver electrode," Chem. Phys. Lett. 26(2), 163-166 (1974).
9. M. Y. Sha et al., "Surface-enhanced Raman scattering tags for rapid and homogeneous detection of circulating tumor cells in the presence of human whole blood," J. Am. Chem. Soc. 130(51), 17214-17215 (2008).
10. E. Smith and G. Dent, Modern Raman Spectroscopy: A Practical Approach, J. Wiley, Hoboken, NJ (2005).
11. K. Kneipp, "Surface-enhanced Raman scattering," Physics Today 60(11), 40 (2007).
12. K. Kneipp, M. Moskovits, and H. Kneipp, Surface-Enhanced Raman Scattering: Physics and Applications, Springer, Berlin, New York (2006).
13. C. L. Haynes, A. D. McFarland, and R. P. V. Duyne, "Surface-enhanced Raman spectroscopy," Anal. Chem. 77(17), 338-A (2005).
14. S. Keren et al., "Noninvasive molecular imaging of small living subjects using Raman spectroscopy," Proc. Natl. Acad. Sci. USA 105(15), 5844-5849 (2008). (Pubitemid 351758460)
15. C. L. Zavaleta et al., "Multiplexed imaging of surface enhanced Raman scattering nanotags in living mice using noninvasive Raman spectroscopy," Proc. Natl. Acad. Sci. USA 106(32), 13511-13516 (2009).
16. X. M. Qian and S. M. Nie, "Single-molecule and single-nanoparticle SERS: from fundamental mechanisms to biomedical applications," Chem. Soc. Rev. 37(5), 912-920 (2008).
17. A. S. Thakor et al., "The fate and toxicity of Raman-active silica-gold nanoparticles in mice," Sci. Transl. Med. 3(79), 79ra33 (2011).
18. A. S. Thakor et al., "Oxidative stress mediates the effects of Ramanactive gold nanoparticles in human cells," Small 7(1), 126-136 (2011).
19. C. L. Zavaleta et al., "Preclinical evaluation of Raman nanoparticle biodistribution for their potential use in clinical endoscopy imaging," Small 7(15), 2232-2240 (2011).
20. M. G. Shim et al., "In vivo near-infrared Raman spectroscopy: Demonstration of feasibility during clinical gastrointestinal endoscopy," Photochem. Photobiol. 72(1), 146-150 (2000).
21. Z. Huang et al., "Raman spectroscopy of in vivo cutaneous melanin," J Biomed. Opt. 9(6), 1198-1205 (2004). (Pubitemid 40168134)
22. Z. Huang et al., "Rapid near-infrared Raman spectroscopy system for real-time in vivo skin measurements," Opt. Lett. 26(22), 1782-1784 (2001). (Pubitemid 33693859)
23. Z. Huang et al., "Near-infrared Raman spectroscopy for optical diagnosis of lung cancer," Int. J. Cancer 107(6), 1047-1052 (2003). (Pubitemid 37429849)
24. M. A. Short et al., "Development and preliminary results of an endoscopic Raman probe for potential in vivo diagnosis of lung cancers," Opt. Lett. 33(7), 711-713 (2008). (Pubitemid 351571465)
25. Y. Komachi et al., "Micro-optical fiber probe for use in an intravascular Raman endoscope," Appl. Opt. 44(22), 4722-4732 (2005). (Pubitemid 41145920)
26. A. Mahadevan-Jansen et al., "Near-infrared Raman spectroscopy for in vitro detection of cervical precancers," Photochem. Photobiol. 68(1), 123-132 (1998). (Pubitemid 128472342)
27. A. Mahadevan-Jansen et al., "Development of a fiber optic probe to measure NIR Raman spectra of cervical tissue in vivo," Photochem. Photobiol. 68(3), 427-431 (1998). (Pubitemid 128472731)
28. A. Robichaux-Viehoever et al., "Characterization of Raman spectra measured in vivo for the detection of cervical dysplasia," Appl. Spectrosc. 61(9), 986-993 (2007). (Pubitemid 47441734)
29. A. Molckovsky et al., "Diagnostic potential of near-infrared Raman spectroscopy in the colon: Differentiating adenomatous from hyperplastic polyps," Gastrointest. Endosc. 57(3), 396-402 (2003). (Pubitemid 36350806)
30. M. V. Schulmerich et al., "Transcutaneous Raman spectroscopy of murine bone in vivo," Appl. Spectrosc. 63(3), 286-295 (2009).
31. A. M. Mohs et al., "Hand-held spectroscopic device for in vivo, and intraoperative tumor detection: Contrast enhancement, detection sensitivity, and tissue penetration," Anal. Chem. 82(21), 9058-9065 (2010).
32. R. J. Mallia et al., "Filter-based method for background removal in high-sensitivity wide-field-surface-enhanced Raman scattering imaging in vivo," J. Biomed. Opt. 17(7), 076017 (2012).
33. P. Z. McVeigh et al., "Development of a widefield SERS imaging endoscope," Proc. SPIE 8217, 821704 (2012).
34. P. Z. McVeigh et al., "Widefield quantitative multiplex surface enhanced Raman scattering imaging in vivo," J. Biomed. Opt. 18(4), 046011 (2013).
35. C. L. Zavaleta et al., "A Raman-based endoscopic strategy for multiplexed molecular imaging," Proc. Natl. Acad. Sci. USA 110(25), E2288-2297 (2013).
36. B. R. Lutz et al., "Spectral analysis of multiplex Raman probe signatures," ACS Nano 2(11), 2306-2314 (2008).
37. X. Qian et al., "In vivo tumor targeting and spectroscopic detection with surface-enhanced Raman nanoparticle tags," Nat. Biotechnol. 26(1), 83-90 (2008).
38. J. T. Liu et al., "Quantifying cell-surface biomarker expression in thick tissues with ratiometric three-dimensional microscopy," Biophys. J. 96(6), 2405-2414 (2009).
39. J. T. Liu et al., "Ratiometric 3-D scanning cytometer for quantifying cell-surface biomarker expression within intact tissues," in Novel Techniques in Microscopy, Optical Society of America (2009).
40. K. M. Tichauer et al., "Advantages of a dual-tracer model over reference tissue models for binding potential measurement in tumors," Phys. Med. Biol. 57(20), 6647-6659 (2012).
41. J. V. Jokerst et al., "Affibody-functionalized gold-silica nanoparticles for Raman molecular imaging of the epidermal growth factor receptor," Small 7(5), 625-633 (2011).
42. C. Zavaleta et al., "Noninvasive Raman spectroscopy in living mice for evaluation of tumor targeting with carbon nanotubes," Nano Lett. 8(9), 2800-2805 (2008).
43. F. L. Pedrotti, L. M. Pedrotti, and L. S. Pedrotti, Introduction to Optics, Pearson/Prentice Hall, Upper Saddle River, NJ (2007).
44. A. Ben-Israel and T. N. E. Greville, Generalized Inverses: Theory and Applications, Wiley, New York (1974).
45. D. Van de Sompel et al., "A hybrid least squares and principal component analysis algorithm for Raman spectroscopy," PLoS One 7(6), e38850 (2012).
46. P. Ghenuche et al., "Kagome hollow-core photonic crystal fiber probe for Raman spectroscopy," Opt. Lett. 37(21), 4371-4373 (2012).
47. P. I. Ookagbare and M. D. Morris, "Fluorocarbon fiber-optic Raman probe for non-invasive Raman spectroscopy," Appl. Spectrosc. 66(6), 728-730 (2012).